San Francisco 49ers betting odds lines ML ATS OU

First look: Cincinnati Bengals at San Francisco 49ers odds and lines

Looking at Sunday’s Cincinnati Bengals at San Francisco 49ers Week 8 NFL odds, lines and trends. Here’s what you need to know.

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The Cincinnati Bengals (3-3) and San Francisco 49ers (5-2) meet for a Week 8 matchup at Levi’s Stadium in Santa Clara, Calif. Kickoff is scheduled for 4:25 p.m. ET (CBS). Below, we look at Bengals vs. 49ers odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Bengals opened 0-2 straight up (SU), before winning 3 of the past 4 games. That includes a 17-13 win over the Seattle Seahawks prior to the bye in Week 7. Cincinnati is 3-0 SU and 2-0-1 against the spread (ATS) in 3 games against the NFC West Division, and 0-3 SU/ATS against all other teams.

The 49ers were on the short end of a 22-17 road loss on Monday night in Minnesota, and now they face the short week. San Francisco opened 5-0 SU, but it has dropped 2 in a row, losing by a combined total of 7 points while failing to cover in each as a favorite.

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Bengals at 49ers odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 5:35 a.m. ET.

Moneyline (ML): Bengals +180 (bet $100 to win $180) | 49ers -215 (bet $215 to win $100)
Against the spread (ATS): Bengals +5.5 (-115) | 49ers -5.5 (-105)
Over/Under (O/U): 45.5 (O: -110 | U: -110)

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2023 betting stats

ML: Bengals 3-3 | 49ers 5-2
ATS: Bengals 2-3-1 | 49ers 4-3
O/U: Bengals 2-4 | 49ers 3-3-1

Bengals at 49ers head-to-head

These teams last met Dec. 12, 2021, in Cincinnati, with the 49ers picking up a 26-23 overtime win as a 1-point favorite. The road team has won each of the past 4 meetings since 2011, while the road team is also 4-0 ATS during that span.

The last time these teams played in the Bay Area was Dec. 20, 2015, and the Bengals came away with a 24-14 win behind 2 TD runs by Jeremy Hill, and a TD reception from QB A.J. McCarron to TE Tyler Kroft. It’s been a while since the Bengals have visited the 49ers at home.

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First look: San Francisco 49ers at Minnesota Vikings odds and lines

Looking at Monday’s San Francisco 49ers at Minnesota Vikings Week 7 NFL odds, lines and trends. Here’s what you need to know.

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The San Francisco 49ers (5-1) and the Minnesota Vikings (2-4) meet for Monday Night Football in Week 7 at U.S. Bank Stadium in Minneapolis. Kickoff is scheduled for 8:15 p.m. ET (ABC/ESPN). Below, we look at 49ers vs. Vikings odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The 49ers took their 1st loss of the season Sunday in Cleveland, falling by a 19-17 score to the Browns. Rookie PK Jake Moody misfired on a a 41-yard game-winning field goal attempt with :06 left in regulation, as the Browns won outright as an 8.5-point underdog.

To make matters worse, the Niners saw both RB Christian McCaffrey (oblique, ribs) and WR Deebo Samuel (shoulder) exit early, and each player is a question mark for Week 7. At least they have an extra day to heal.

The 49ers saw a 3-game cover streak snapped, while the total pushed at most shops. The Over is still 3-1-1 in the past 5 games overall, while going 1-1-1 in 3 outings on the road.

The Vikings scratched out a 19-13 victory in the rain and wind in Chicago, covering a 3-point number. Minnesota has done its best work on the road, going 2-1 SU and 2-0-1 ATS. At home, the Vikings are 0-3 SU/ATS. The Under cashed Sunday, and it is 5-1 overall, including 3-0 at home.

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49ers at Vikings odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:51 a.m. ET.

Moneyline (ML): 49ers -300 (bet $300 to win $100) | Vikings +240 (bet $100 to win $240)
Against the spread (ATS): 49ers -7 (-110) | Vikings +7 (-110)
Over/Under (O/U): 44 (O: -110 | U: -110)

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2023 betting stats

ML: 49ers 5-1 | Vikings 2-4
ATS: 49ers 4-2 | Vikings 2-3-1
O/U: 49ers 3-2-1 | Vikings 1-5

49ers at Vikings head-to-head

The last meeting in this series was Nov. 28, 2021, in Santa Clara, as the 49ers won 34-26 as a 4-point favorite. The Over (49) cashed in that matchup, snapping a 4-game Under streak in the series.

San Francisco has won 3 of the past 4 meetings outright, while also covering 3 of the past 4 in the series. The home team has won and covered 5 straight meetings, too, with the home team winning 6 in a row. The road team last won outright when the Vikings won 27-7 at Candlestick Park on Dec. 9, 2007.

This will be the 50th meeting with the 49ers ahead 25-23-1, including 5-1 in the postseason.

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First look: San Francisco 49ers at Cleveland Browns odds and lines

Looking at Sunday’s San Francisco 49ers at Cleveland Browns Week 6 NFL odds, lines and trends. Here’s what you need to know.

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The San Francisco 49ers (5-0) and the Cleveland Browns (2-2) meet on Sunday for a Week 6 matchup at Cleveland Browns Stadium. Kickoff is scheduled for 1 p.m. ET (FOX). Below, we look at 49ers vs. Browns odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The 49ers remain 1 of 2 unbeaten teams in the NFL after dismantling the Dallas Cowboys 42-10 on Sunday Night Football. RB Christian McCaffrey scored a touchdown in his 14th straight game.

The Niners have scored 30 or more points in every game this season, including a 30-7 road win against the Pittsburgh Steelers in Week 1, an AFC North Division opponent.

The 49ers easily covered against the Cowboys, and they’re now 4-1 against the spread (ATS), with covers in 3 straight. The Over has cashed in back-to-back games, and 3 of the past 4 outings. The Under cashed in Week 1 in the 1st meeting vs. an AFC opponent.

The Browns are coming off a bye week. QB Deshaun Watson missed the game prior to the bye due to a shoulder injury. He is expected to be ready for Week 6. Cleveland has alternated wins and losses in the first 4 weeks, while also alternating covers and non-covers. The Under is 3-1 in 4 outings. This is Cleveland’s 1st game vs. an NFC foe this season.

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49ers at Browns odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 6:11 a.m. ET.

Moneyline (ML): 49ers -188 (bet $188 to win $100) | Browns +158 (bet $100 to win $158)
Against the spread (ATS): 49ers -3.5 (-110) | Browns +3.5 (-110)
Over/Under (O/U): 41.5 (O: -105 | U: -115)

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2023 betting stats

ML: 49ers 5-0 | Browns 2-2
ATS: 49ers 4-1 | Browns 2-2
O/U: 49ers 3-2 | Browns 1-3

49ers at Browns head-to-head

These teams haven’t met since Oct. 7, 2019, a 31-3 victory by the 49ers at Levi’s Stadium in Santa Clara.

The last time these teams met at Cleveland Browns Stadium, the Browns picked up a 24-10 win with Johnny Manziel at QB as 2.5-point favorites as the Under (43) cashed on Dec. 13, 2015.

The home team has won and covered each of the past 4 games in the series. The last time the road team won was a 13-12 win by the Browns in Candlestick Park on Sept. 21, 2003.

This will the 30th all-time meeting with the Browns leading 19-10.

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First look: Dallas Cowboys at San Francisco 49ers odds and lines

Looking at Sunday’s Dallas Cowboys at San Francisco 49ers Week 5 NFL odds, lines and trends. Here’s what you need to know.

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The Dallas Cowboys (3-1) pay a visit to the San Francisco 49ers (4-0) Sunday in a battle of NFC powerhouses. Kickoff from Levi’s Stadium is set for 8:20 p.m. ET (NBC). Below, we look at Cowboys vs. 49ers odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

Dallas routed the New England Patriots 38-3 as 6-point favorites on Sunday as QB Dak Prescott completed 28 of 34 passes for 261 yards and 1 TD. But it was the Dallas defense that took the game over. The Cowboys’ defensive unit scored TDs on a fumble return and an interception while forcing 3 turnovers and 2 sacks.

San Francisco stayed undefeated by picking up a 35-16 win Sunday vs. the Arizona Cardinals as 14-point favorites. RB Christian McCaffrey had a career-high 4 TDs. QB Brock Purdy hit 20 of 21 passes for 283 yards and had 2 TDs. His 95% completion percentage vs. Arizona set a franchise record.

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Cowboys at 49ers odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 11:54 p.m. ET.

Moneyline (ML): Cowboys +146 (bet $100 to win $146) | 49ers -174 (bet $174 to win $100)
Against the spread (ATS): Cowboys +3.5 (-115) | 49ers -3.5 (-105)
Over/Under (O/U): 45.5 (O: -110 | U: -110)

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2023 betting stats

ML: Cowboys 3-1 | 49ers 4-0
ATS: Cowboys 3-1 | 49ers 3-1
O/U: Cowboys 2-2 | 49ers 2-2

Cowboys vs. 49ers head-to-head

The all-time series between these 2 storied franchises is 19-19-1. The Niners have won the last 2 meetings, both in the playoffs. San Francisco beat Dallas 19-12 in 2023’s NFC Divisional round and 23-17 in 2022’s NFC Wild Card round.

The Cowboys lead 6-4 in the last 10 meetings and are 4-1 in the last 5 meetings in San Francisco.

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First look: Arizona Cardinals at San Francisco 49ers odds and lines

Looking at Sunday’s Arizona Cardinals at San Francisco 49ers Week 4 NFL odds, lines and trends. Here’s what you need to know.

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The Arizona Cardinals (1-2) visit the San Francisco 49ers (3-0) Sunday in Week 4. Kickoff from Levi’s Stadium is at 4:25 p.m. ET (FOX). Below, we look at Cardinals vs. 49ers odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Cardinals picked up their first win of the season in Week 3, defeating the Dallas Cowboys 28-16 as 11-point home underdogs. Arizona rushed for 222 yards in its 3rd straight game vs. the NFC East.

The 49ers improved to 3-0 with a 30-12 win over the New York Giants as 10.5-point favorites on Thursday Night Football. QB Brock Purdy has thrown 4 touchdown passes without an interception so far this season.

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Cardinals at 49ers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:53 p.m. ET.

Moneyline (ML): Cardinals +600 (bet $100 to win $600) | 49ers -900 (bet $900 to win $100)
Against the spread (ATS): Cardinals +14 (-110) | 49ers -14 (-xxx)
Over/Under (O/U): 43.5 (O: -110 | U: -110)

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2023 betting stats

ML: Cardinals 1-2 | 49ers 3-0
ATS: Cardinals 3-0 | 49ers 2-1
O/U: Cardinals 2-1 | 49ers 1-2

Cardinals vs. 49ers head-to-head

Dating back to 1961, the 49ers lead the all-time series 34-29. They won both meetings last season and have won 4 of the last 7 meetings.

Purdy is 2-0 in 2 career starts against the Cardinals and has 3 touchdown passes with no interceptions.

Cardinals QB Josh Dobbs has never played against the 49ers.

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First look: New York Giants at San Francisco 49ers odds and lines

Looking at Thursday’s New York Giants at San Francisco 49ers Week 3 NFL odds, lines and trends. Here’s what you need to know.

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The New York Giants (1-1) and the San Francisco 49ers (2-0) meet on Thursday Night Football at Levi’s Stadium in Santa Clara, Calif. Kickoff is scheduled for 8:15 p.m. ET (Prime Video). Below, we look at Giants vs. 49ers odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Giants opened the season with a 40-0 egg-laying at home on Sunday Night Football against the Dallas Cowboys. In Week 2, it appeared history would repeat itself, as New York was down 20-0 at halftime against the Arizona Cardinals. However, the G-Men rallied for a 31-28 road win.

The victory came with a price, however, as RB Saquon Barkley suffered an ankle injury late in the game. X-rays were negative, but he’ll have an MRI to determine the severity. He could be a question mark with the quick turnaround. If so, RB Matt Breida might be in line to start against his original NFL club.

The 49ers went on the road in Week 1 and spanked the Pittsburgh Steelers 30-7 for the cover and Under. San Francisco then hit the road for a 30-23 victory against the Los Angeles Rams, failing to cover after LA coach Sean McVay elected to kick a field goal with :00 left in regulation, angering plenty. The Over cashed in the divisional battle, too.

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Giants at 49ers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 4:56 a.m. ET.

Moneyline (ML): Giants +350 (bet $100 to win $350) | 49ers -450 (bet $450 to win $100)
Against the spread (ATS): Giants +10 (-110) | 49ers -10 (-110)
Over/Under (O/U): 45 (O: -110 | U: -110)

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2023 betting stats

ML: Giants 1-1 | 49ers 2-0
ATS: Giants 0-2 | 49ers 1-1
O/U: Giants 1-1 | 49ers 1-1

Giants at 49ers head-to-head

This is the 1st regular-season meeting since Sept. 27, 2020, in the Meadowlands, with the 49ers coming away with a 36-9 victory, covering a 3-point number as the Over (44) just came in.

The last time these teams met in the Bay Area, the G-Men shocked the Niners 27-23 on Nov. 12, 2018, as 3-point underdogs as the Over (45) cashed. The 49ers are 4-1 ATS in the past 5 meetings, while the Over has cashed in 4 straight in the series.

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First look: San Francisco 49ers at Los Angeles Rams odds and lines

Looking at Xday’s VFullname at HFullname Week X NFL odds, lines and trends. Here’s what you need to know.

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After blowing out each of their opponents in Week 1, the Los Angeles Rams (1-0) and the San Francisco 49ers (1-0) will square off on Sunday afternoon at SoFi Stadium in Inglewood, Calif. Kickoff is set for 4:05 p.m. ET (FOX). Below, we look at 49ers vs. Rams odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The 49ers crushed the Pittsburgh Steelers on Sunday, cruising to a 30-7 win after jumping out to a 20-0 lead in the 1st half. QB Brock Purdy had 220 yards and 2 TDs, both to WR Brandon Aiyuk.

The Rams also made a statement in the season opener, dominating the Seattle Seahawks in a 30-13 victory. LA allowed just 12 second-half yards to the Seahawks and outscored them 23-0 in the final 30 minutes, showing the defense may be better than expected.

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49ers at Rams odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 9:45 a.m. ET.

Moneyline (ML): 49ers -300 (bet $300 to win $100) | Rams +240 (bet $100 to win $240)
Against the spread (ATS): 49ers -7 (-110) | Rams +7 (-110)
Over/Under (O/U): 42.5 (O: -110 | U: -110)

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2023 betting stats

ML: 49ers 1-0 | Rams 1-0
ATS: 49ers 1-0 | Rams 1-0
O/U: 49ers 0-1 | Rams 0-1

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49ers vs. Rams head-to-head

The 49ers and Rams meet twice a year, sometimes 3 times if both make the playoffs. But in the last 4 seasons, the 49ers have owned the Rams in the regular season. The 49ers are 8-0 in their last 8 regular-season games against the Rams, which dates back to the 2019 season.

The Rams have 1 win since then, which came in the NFC Championship Game in January 2022, but the 49ers have had their number in regular-season meetings.

In their last 10 matchups, the 49ers are 8-2 straight-up and ATS while the Under is 6-4. The 49ers have covered the spread in 7 straight games against LA.

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First look: San Francisco 49ers at Pittsburgh Steelers odds and lines

Looking at Sunday’s San Francisco 49ers at Pittsburgh Steelers Week 1 NFL odds, lines and trends. Here’s what you need to know.

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The San Francisco 49ers will travel to take on the Pittsburgh Steelers in the season opener for both teams Sunday at 1 p.m. (FOX). Below, we look at 49ers vs. Steelers odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

After an offseason of whining about what could have been, 49ers fans will have a chance to finally prove it on the field Sunday against the Pittsburgh Steelers.

Starting QB Brock Purdy has made a great recovery and Sam Darnold was able to beat out Trey Lance as the backup. Lance, who never lived up to being the No. 3 overall pick in the draft, was traded to the Dallas Cowboys. With Darnold now the only backup to Purdy, San Fransisco will have to hope its QB luck changes in 2023.

The Steelers had a sluggish start to the 2022 season. Rookie QB Kenny Pickett took a long time to find his comfort level. When he did, he found a connection with WR George Pickens. After a full season of workouts, this could become the next great QB-WR duo for the Steelers. If Najee Harris can return to his rookie form of 2 years ago (307 carries, 1,200 yards, 7 TDs), the Steelers offense could once again shine bright.

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49ers at Steelers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 10:26 p.m. ET.

Moneyline (ML): 49ers -145 (bet $145 to win $100) | Steelers +120 (bet $100 to win $120)
Against the spread (ATS): 49ers -2.5 (-110) | Steelers +2.5 (-110)
Over/Under (O/U): 41 (O: -110 | U: -110)

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2022 betting stats

ML: 49ers 15-5 | Steelers 9-8
ATS: 49ers 13-7 | Steelers 10-6-1
O/U: 49ers 10-10 | Steelers 7-10

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49ers vs. Steelers head-to-head

These teams have not met since the 2019 season, which the 49ers won 24-20 but failed to cover as 6-point home favorites. They are 2-2 in the past 4 meetings, dating back to 2007, with the home team going 4-0 straight up and the Steelers cashing 3-1 ATS.

The 2019 was the only time the underdog covered in the past 4 contests. One of these trends will lose Sunday as Pittsburgh is the underdog and the home team.

Both teams will have a 2nd-year QB leading their offenses. But only Pickett comes into the game completely healthy and with no concerns.

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First look: San Francisco 49ers at Philadelphia Eagles odds and lines

Looking at Sunday’s San Francisco 49ers at Philadelphia Eagles NFC title game odds, lines and trends. Here’s what you need to know.

The San Francisco 49ers (15-4) visit the Philadelphia Eagles (15-3) in the NFC Championship Game Sunday. Kickoff from Lincoln Financial Field is set for 3 p.m. ET (FOX). Below, we look at 49ers vs. Eagles odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The 49ers won their 12th consecutive game Sunday, beating the Dallas Cowboys 19-12 in the Divisional Round. Second-seeded San Francisco, which was a 3.5-point home favorite, was able to pull out the victory and rookie QB Brock Purdy improved to 7-0 as a starter. The win marked the 2nd season in a row that San Francisco beat Dallas in the playoffs.

The Eagles are coming off a 38-7 Divisional Round blowout win as 8-point home favorites vs. the New York Giants Saturday in a game many expected to be close. The Eagles, who had the advantage of a bye the previous week as the No. 1 seed, jumped out to a 14-0 lead after the opening quarter and led 28-0 at the half. Philadelphia finished with 416 total yards, while holding New York to 227. Philly won the turnover battle (1-0), had double the 1st downs (26-13) and led time of possession (35:43 to 24:17).

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49ers at Eagles odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 4:26 a.m. ET.

Moneyline (ML): 49ers +145 (bet $100 to win $145) | Eagles -125 (bet $125 to win $100)
Against the spread (ATS): 49ers +2.5 (-105) | Eagles -2.5 (-115)
Over/Under (O/U): 45.5 (O: -108 | U: -112)

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2022 betting stats (including postseason)

ML: 49ers 15-4 | Eagles 15-3
ATS: 49ers 13-6 | Eagles 9-9
O/U: 49ers 10-9 | Eagles 10-8

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49ers vs. Eagles head-to-head

Sunday will mark the 36th meeting between these franchises. The 49ers lead the all-time series 20-14-1, including a 14-0 shutout at home in a 1996 NFC Wild Card Game — the only time these 2 met in the postseason.

Philly won 5 straight vs. San Francisco from 2005-10, but San Francisco leads the series 3-2 since. They last met in Week 2 of 2021 with the 49ers winning 17-11 as 3-road favorites.

Purdy has never faced the Eagles, while Philly QB Jalen Hurts is 0-1 as a starter vs. the 49ers. Hurts threw for 190 yards (12 of 23 attempts) with no TDs or INTs in the 2021 contest and played sparingly against the 49ers in 2020 — his rookie season — with just 3 carries and no pass attempts.

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First look: Dallas Cowboys at San Francisco 49ers odds and lines

Looking at Sunday’s Dallas Cowboys at San Francisco 49ers Divisional Round NFL odds, lines and trends. Here’s what you need to know.

The Dallas Cowboys (13-5) and San Francisco 49ers (14-4) meet in the Divisional Round of the NFL playoffs on Sunday with a chance to advance to the NFC Championship Game. Kickoff from Levi’s Stadium will be at 6:30 p.m. ET (FOX). Below, we look at Cowboys vs. 49ers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Cowboys eliminated the Tampa Bay Buccaneers with a 31-14 road win Monday. It was their 1st-ever win against QB Tom Brady, and also their first road playoff win since 1993. QB Dak Prescott led the Cowboys with 4 passing TDs and a rushing TD, dominating the Bucs through the air with a near-perfect performance.

The 49ers crushed the Seattle Seahawks 41-23 at home Saturday. They trailed 17-16 at halftime but outscored Seattle 25-6 in the 2nd half to advance to the Divisional Round. QB Brock Purdy threw 3 TDs and 332 yards and rushed for another score in his playoff debut. San Francisco covered the spread as a 10-point favorite.

Also see: All Divisional Round odds and lines

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Cowboys vs. 49ers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 12:43 p.m. ET.

Moneyline (ML): Cowboys +160 (bet $100 to win $160) | 49ers -190 (bet $190 to win $100)
Against the spread (ATS): Cowboys +3.5 (-113) | 49ers -3.5 (-107)
Over/Under (O/U): 46 (O: -109 | U: -111)

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2022-23 betting stats (including postseason)

ML: Cowboys 13-5 | 49ers 14-4
ATS: Cowboys 10-7-1 | 49ers 12-6
O/U: Cowboys 8-9-1 | 49ers 10-8

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Cowboys vs. 49ers head-to-head

This is the 2nd straight year the Cowboys and 49ers will meet in the playoffs. San Francisco beat the Cowboys 23-17 in the Wild Card Round last year, eventually making it to the NFC Championship Game. This is the 39th all-time meeting between these storied franchises.

It will also be the 9th time they meet in the playoffs, with the Cowboys holding a 5-3 edge in their postseason matchups with San Francisco.

In the last 7 meetings between these teams, the Cowboys are 4-2-1 ATS and the total has gone Over 4 times. Dallas is also 5-2 SU against the 49ers in their last 7 games but they’ve lost their last 2 playoff games against San Francisco.

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