Clemson at Louisville college basketball odds, picks and best bets

Previewing Saturday’s Clemson Tigers at Louisville Cardinals sports betting odds and lines, with college basketball betting picks and tips.

The Clemson Tigers (10-8) visit the Louisville Cardinals (16-3) in a Saturday matinee at the KFC Yum! Center in Louisville, Ky. Tip-off is set for 2 p.m. ET. We analyze the Clemson-Louisville odds and betting lines, with college basketball betting advice and tips around this matchup.

Clemson at Louisville: Three things you need to know

1. Louisville — the No. 5 team in the nation on the USA Today Sports Coaches Poll — is on a roll with five straight wins. This surge is coming on the heels of bracketing the New Year with losses to Kentucky (Dec. 28) and Florida State (Jan. 4). The Cardinals have been dialed in from distance, shooting 42.6% from 3-point range over the five straight wins.

2. While it certainly isn’t one, this game feels like a tussle for the ACC, as both teams have recently defeated the now-No. 8 Duke Blue Devils: Clemson Jan. 14 and Louisville Jan. 18.

3. Other recent wins for UL — the non-Duke victories — haven’t been all that commanding, but can the Tigers capitalize on the road, where they haven’t looked great overall? Clemson is weak on the offensive boards and hasn’t created a lot of turnovers lately.

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Clemson at Louisville: Odds, betting lines and picks

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 9:55 a.m. ET.


Louisville 69, Clemson 61

Moneyline (ML)

LOUISVILLE (-556) is a fair price, worthy of consideration in middling a double-digit spread. In other words — a play on the Cardinals for the straight-up win and on the Tigers carrying the points.

Against the Spread (ATS)

The Tigers are 8-2 against the spread in their last 10 games as an underdog. The Cardinals are 1-3-1 ATS in their last five games as a favorite. The underdog is 4-1 ATS over the last five meetings between these ACC foes.

The lean is on CLEMSON (+10.5, -125), but it’s only a slight lean.

Over/Under (O/U)

The Over is 5-1 in Clemson’s last six games and 5-1 in Louisville’s last six Saturday games. The strongest play of these three is the OVER 127 (-125).

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