First look: San Francisco 49ers at Pittsburgh Steelers odds and lines

Looking at Sunday’s San Francisco 49ers at Pittsburgh Steelers Week 1 NFL odds, lines and trends. Here’s what you need to know.

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The San Francisco 49ers will travel to take on the Pittsburgh Steelers in the season opener for both teams Sunday at 1 p.m. (FOX). Below, we look at 49ers vs. Steelers odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

After an offseason of whining about what could have been, 49ers fans will have a chance to finally prove it on the field Sunday against the Pittsburgh Steelers.

Starting QB Brock Purdy has made a great recovery and Sam Darnold was able to beat out Trey Lance as the backup. Lance, who never lived up to being the No. 3 overall pick in the draft, was traded to the Dallas Cowboys. With Darnold now the only backup to Purdy, San Fransisco will have to hope its QB luck changes in 2023.

The Steelers had a sluggish start to the 2022 season. Rookie QB Kenny Pickett took a long time to find his comfort level. When he did, he found a connection with WR George Pickens. After a full season of workouts, this could become the next great QB-WR duo for the Steelers. If Najee Harris can return to his rookie form of 2 years ago (307 carries, 1,200 yards, 7 TDs), the Steelers offense could once again shine bright.

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49ers at Steelers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 10:26 p.m. ET.

  • Moneyline (ML): 49ers -145 (bet $145 to win $100) | Steelers +120 (bet $100 to win $120)
  • Against the spread (ATS): 49ers -2.5 (-110) | Steelers +2.5 (-110)
  • Over/Under (O/U): 41 (O: -110 | U: -110)

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2022 betting stats

  • ML: 49ers 15-5 | Steelers 9-8
  • ATS: 49ers 13-7 | Steelers 10-6-1
  • O/U: 49ers 10-10 | Steelers 7-10

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49ers vs. Steelers head-to-head

These teams have not met since the 2019 season, which the 49ers won 24-20 but failed to cover as 6-point home favorites. They are 2-2 in the past 4 meetings, dating back to 2007, with the home team going 4-0 straight up and the Steelers cashing 3-1 ATS.

The 2019 was the only time the underdog covered in the past 4 contests. One of these trends will lose Sunday as Pittsburgh is the underdog and the home team.

Both teams will have a 2nd-year QB leading their offenses. But only Pickett comes into the game completely healthy and with no concerns.

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First look: Seattle Seahawks at San Francisco 49ers odds and lines

Looking at Saturday’s Seattle Seahawks at San Francisco 49ers Wild Card Game NFL odds, lines and trends. Here’s what you need to know.

The Seattle Seahawks (9-8) and San Francisco 49ers (13-4) will open the postseason slate on Saturday afternoon when they square off at Levi’s Stadium in the Wild Card round. Kickoff is set for 4:30 p.m. ET (FOX). Below, we look at Seahawks vs. 49ers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Seahawks got into the playoffs with the help of the Detroit Lions, who took down the Green Bay Packers on Sunday night after the Seahawks beat the Los Angeles Rams 19-16 in overtime. Had the Packers beaten the Lions in the final Week 18 game, the Seahawks would have been eliminated.

The 49ers are cruising into the postseason, winning their last 10 games after starting the season 3-4. The 49ers blew out the Arizona Cardinals 38-13 covering a double-digit spread and it was their 7th win by 10-plus points since Week 8. San Francisco ended the season with the No. 1 defense in points and yards allowed, as well as the 5th-ranked offense in total yards despite being led by 3rd-string QB Brock Purdy.

Also see: All Wild Card round odds and lines

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Seahawks at 49ers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:29  p.m. ET.

  • Moneyline (ML): Seahawks +410 (bet $100 to win $410) | 49ers -525 (bet $520 to win $100)
  • Against the spread (ATS): Seahawks +10 (-109) | 49ers -10 (-111)
  • Over/Under (O/U): 43 (O: -110 | U: -110)

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2022 betting stats

  • ML: Seahawks 9-8 | 49ers 13-4
  • ATS: Seahawks 7-10 | 49ers 11-6
  • O/U: Seahawks 8-9 | 49ers 9-8

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Seahawks vs. 49ers head-to-head

This will be the 3rd meeting of the season between these NFC West rivals. The 49ers swept the Seahawks during the regular season, beating them 27-7 in Week 2 and 21-13 on the road in Week 15. Prior to this season, the 49ers had lost 4 games in a row to Seattle dating back to the start of the 2020 campaign.

In the last 10 meetings between the Seahawks and 49ers, they’ve each won 5 games ATS and straight-up. The Over/Under is 6-3-1 in that same span, though the Under has hit in each of the last 2 games.

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First look: Seattle Seahawks at San Francisco 49ers odds and lines

Looking at Sunday’s Seattle Seahawks at San Francisco 49ers Week 2 NFL odds, lines and trends. Here’s what you need to know.

The Seattle Seahawks (1-0) and San Francisco 49ers (0-1) meet Sunday for a Week 2 contest at Levi’s Stadium. Kickoff is set for at 4:05 p.m. ET (FOX). Below, we look at Seahawks vs. 49ers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

Seattle is coming off a triumph over the Denver Broncos on Monday Night Football. The Seahawks scored all of their 17 points over the first 28 minutes of clock time and then held on for a 17-16 win. They won the game despite racking up just 253 total yards.

The 49ers lost a 19-10 game at the Chicago Bears Sunday. In rainy conditions, QB Trey Lance was held to a 13-for-28 mark in passing the football. The ‘Niners lost despite holding the Bears to just 204 total yards.

Also seeAll Week 2 odds and lines

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Seahawks at 49ers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 9:22 a.m. ET.

  • Money line: Seahawks +330 (bet $100 to win $330) | 49ers -420 (bet $420 to win $100)
  • Against the spread (ATS): Seahawks +8.5 (-112) | 49ers -8.5 (-108)
  • Over/Under (O/U): 42.5 (O: -108 | U: -112)

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2022 betting stats

  • ML: Seahawks 1-0 | 49ers 0-1
  • ATS: Seahawks 1-0 | 49ers 0-1
  • O/U: Seahawks 0-1 | 49ers 0-1

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Seahawks vs. 49ers head-to-head

Seattle beat San Francisco twice last season, both times in 1-score games. Six of the last 7 games between these NFC West foes have been decided by 8 points or fewer.

The all-time history between the Seahawks and 49ers includes 47 games; Seattle is 30-17 across those games.

Seattle earned ATS wins in both games last season and is 3-1 ATS in the last 4 series meetings. The Over is 3-1 across those same 4 games.

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First look: Seattle Seahawks at San Francisco 49ers odds and lines

Looking at Sunday’s Seattle Seahawks at San Francisco 49ers Week 4 NFL odds, lines and trends. Here’s what you need to know.

In their first of two meetings this season, the Seattle Seahawks (1-2) will visit the San Francisco 49ers (2-1) on Sunday. Kickoff from Levi’s Stadium will be at 4:05 p.m. ET. Below, we look at the Seahawks vs. 49ers odds and lines; check back for our NFL picks and predictions.

The Seahawks have dropped two straight after beating the Indianapolis Colts in Week 1, losing to the Tennessee Titans in overtime and getting blown out by the Minnesota Vikings Sunday, 30-17.

It’s been a shaky start to the year for Seattle, which has allowed the most yards in the NFL through three weeks. QB Russell Wilson has been great once again, throwing seven touchdown passes and no interceptions so far.

The 49ers lost to the Green Bay Packers on a last-second field goal Monday night, falling 30-28 at home. QB Jimmy Garoppolo remains the starter over QB Trey Lance, with San Francisco ranking 16th in passing yards and 19th in total offense. The defense has been just average, too, ranking 16th in yards allowed and 17th in points allowed through three games.

Seahawks at 49ers odds, spread and line

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 11:11 a.m. ET.

  • Money line: Seahawks +125 (bet $100 to win $125) | 49ers -155 (bet $155 to win $100)
  • Against the spread (ATS): Seahawks +2.5, +105 (bet $100 to win $105) | 49ers -2.5, -130 (bet $130 to win $100)
  • Total (O/U): 51.5, Over -115 (bet $115 to win $100) | Under -105 (bet $105 to win $100)

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2021 betting stats:

  • ML: Seahawks 1-2 | 49ers 2-1
  • ATS: Seahawks 1-2 | 49ers 1-2
  • O/U: Seahawks 1-2 | 49ers 2-1

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Seahawks at 49ers head-to-head

The Seahawks have had the 49ers’ number in recent years and own the all-time series lead 28-17. Seattle swept San Francisco last season and has won 12 of the last 14 games against the 49ers dating back to 2014. They’ve each scored at least 21 points in each of the last five meetings.

The Seahawks beat San Francisco 26-23 in Week 17 last season, which came after they won the first meeting of the season, 37-27, back in November. The only losses by Seattle to the 49ers since 2014 came on Dec. 29, 2019 (26-21) and Dec. 16, 2018 (26-23 in OT).

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

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