First look: Dallas Cowboys at San Francisco 49ers odds and lines

Looking at Sunday’s Dallas Cowboys at San Francisco 49ers Week 5 NFL odds, lines and trends. Here’s what you need to know.

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The Dallas Cowboys (3-1) pay a visit to the San Francisco 49ers (4-0) Sunday in a battle of NFC powerhouses. Kickoff from Levi’s Stadium is set for 8:20 p.m. ET (NBC). Below, we look at Cowboys vs. 49ers odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

Dallas routed the New England Patriots 38-3 as 6-point favorites on Sunday as QB Dak Prescott completed 28 of 34 passes for 261 yards and 1 TD. But it was the Dallas  defense that took the game over. The Cowboys’ defensive unit scored TDs on a fumble return and an interception while forcing 3 turnovers and 2 sacks.

San Francisco stayed undefeated by picking up a 35-16 win Sunday vs. the Arizona Cardinals as 14-point favorites. RB Christian McCaffrey had a career-high 4 TDs. QB Brock Purdy hit 20 of 21 passes for 283 yards and had 2 TDs. His 95% completion percentage vs. Arizona set a franchise record.

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Cowboys at 49ers odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 11:54 p.m. ET.

  • Moneyline (ML): Cowboys +146 (bet $100 to win $146) | 49ers -174 (bet $174 to win $100)
  • Against the spread (ATS): Cowboys +3.5 (-115) | 49ers -3.5 (-105)
  • Over/Under (O/U): 45.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Cowboys 3-1 | 49ers 4-0
  • ATS: Cowboys 3-1 | 49ers 3-1
  • O/U: Cowboys 2-2 | 49ers 2-2

Cowboys vs. 49ers head-to-head

The all-time series between these 2 storied franchises is 19-19-1. The Niners have won the last 2 meetings, both in the playoffs. San Francisco beat Dallas 19-12 in 2023’s NFC Divisional round and 23-17 in 2022’s NFC Wild Card round.

The Cowboys lead 6-4 in the last 10 meetings and are 4-1 in the last 5 meetings in San Francisco.

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First look: Dallas Cowboys at San Francisco 49ers odds and lines

Looking at Sunday’s Dallas Cowboys at San Francisco 49ers Divisional Round NFL odds, lines and trends. Here’s what you need to know.

The Dallas Cowboys (13-5) and San Francisco 49ers (14-4) meet in the Divisional Round of the NFL playoffs on Sunday with a chance to advance to the NFC Championship Game. Kickoff from Levi’s Stadium will be at 6:30 p.m. ET (FOX). Below, we look at Cowboys vs. 49ers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Cowboys eliminated the Tampa Bay Buccaneers with a 31-14 road win Monday. It was their 1st-ever win against QB Tom Brady, and also their first road playoff win since 1993. QB Dak Prescott led the Cowboys with 4 passing TDs and a rushing TD, dominating the Bucs through the air with a near-perfect performance.

The 49ers crushed the Seattle Seahawks 41-23 at home Saturday. They trailed 17-16 at halftime but outscored Seattle 25-6 in the 2nd half to advance to the Divisional Round. QB Brock Purdy threw 3 TDs and 332 yards and rushed for another score in his playoff debut. San Francisco covered the spread as a 10-point favorite.

Also seeAll Divisional Round odds and lines

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Cowboys vs. 49ers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 12:43 p.m. ET.

  • Moneyline (ML): Cowboys +160 (bet $100 to win $160) | 49ers -190 (bet $190 to win $100)
  • Against the spread (ATS): Cowboys +3.5 (-113) | 49ers -3.5 (-107)
  • Over/Under (O/U): 46 (O: -109 | U: -111)

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2022-23 betting stats (including postseason)

  • ML: Cowboys 13-5 | 49ers 14-4
  • ATS: Cowboys 10-7-1 | 49ers 12-6
  • O/U: Cowboys 8-9-1 | 49ers 10-8

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Cowboys vs. 49ers head-to-head

This is the 2nd straight year the Cowboys and 49ers will meet in the playoffs. San Francisco beat the Cowboys 23-17 in the Wild Card Round last year, eventually making it to the NFC Championship Game. This is the 39th all-time meeting between these storied franchises.

It will also be the 9th time they meet in the playoffs, with the Cowboys holding a 5-3 edge in their postseason matchups with San Francisco.

In the last 7 meetings between these teams, the Cowboys are 4-2-1 ATS and the total has gone Over 4 times. Dallas is also 5-2 SU against the 49ers in their last 7 games but they’ve lost their last 2 playoff games against San Francisco.

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