College Football Expert Picks, Predictions: Week 5

College football expert picks and predictions for Week 5 highlighted by Arkansas at Alabama, Michigan at Iowa, and NC State at Clemson

College football expert picks, predictions for Week 5, including Arkansas at Alabama, Michigan at Iowa, and NC State at Clemson


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College Football Expert Picks, Predictions: Week 5

* next to the pick means the team will win, but not cover.
Click on each game for the game preview and CFN Prediction

Utah State at BYU

Line: BYU -24, o/u: 60.5

Eric Bolin, RazorbacksWire.com: BYU
Evan Bredeson, CornhuskersWire.com: BYU
Tony Cosolo, ColoradoBuffaloesWire.com: BYU*
Jeff Feyerer, CFN: BYU
Pete Fiutak, CFN: BYU
Cami Griffin, LonghornsWire.com: BYU
Dan Harralson, VolsWire.com: BYU*
Phil Harrison, BuckeyesWire.com: BYU*
Jeremy Mauss, MWwire.com BYU*
Kevin McGuire, NittanyLionsWire.com: BYU
Big Game Ben Niewoehner, CFN BYU
E, CFN BYU*
Tyler Nettuno, LSUTigerswire.com BYU
Zack Pearson, TarHeelswire.com BYU
Nick Shepkowski, FightingIrishWire.com: BYU
Scott Steehn, WinnersandWhiners.com: BYU
Joe Vitale, UGAWire.com: BYU
Clucko the Chicken (a coin flip), CFN: Utah State
CONSENSUS PICK: BYU

Week 5 College Football Expert Picks
Utah State at BYU | Tulane at Houston
UTSA at Middle Tenn | SDSU at Boise St
Washington at UCLA | New Mexico at UNLV
Michigan at Iowa | Kentucky at Ole Miss
Oklahoma at TCU | Purdue at Minnesota
Alabama at Arkansas | Rutgers at Ohio St
Okla St at Baylor | Northwestern at Penn St
Wake Forest at Florida St | TA&M at Miss St
LSU at Auburn | Georgia at Missouri
NC St at Clemson | West Virginia at Texas
Arizona State at USC | Stanford at Oregon
Results So Far | NFL Week 4 Experts Picks

NEXT: Tulane at Houston Expert Picks, Predictions

ACC Predictions, Schedule, Game Previews, Lines, TV: Week 5

ACC college football game previews and schedule for Week 5 of the 2022 season

ACC schedule and previews for all of the Week 5 games, highlighted by NC State at Clemson, Wake Forest at Florida State and Virginia at Duke


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Click on each game for the preview and prediction

Results So Far
Straight Up 39-8, ATS 21-24-2, o/u 35-11-1 

Saturday, October 1

Louisville at Boston College

12:00, ACC Network
Line: Louisville -15.5, o/u: 51

Wake Forest at Florida State

3:30, ABC
Line: Florida State -7, o/u: 64

Virginia Tech at North Carolina

3:30, ACC Network
Line: North Carolina -9.5, o/u: 51.5

Wagner at Syracuse

5:00, ACC Network/ESPN+
Line: Syracuse -55, o/u: 60

NC State at Clemson

7:30, ABC
Line: Clemson -6.5, o/u: 39.5

Virginia at Duke

7:30, ESPN3
Line: Duke -2.5, o/u: 49

Georgia Tech at Pitt

8:00, ACC Network
Line: Pitt -22, o/u: 49

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Roundup: Overrated, Underrated, What it all Means
CFN 1-131 Rankings | Bowl Projections
What 12-Team Playoff Would Look Like
Hot Seat Coach Rankings after Week 4
Think, Know, Believe: Football Smack Talk

Syracuse vs Wagner Prediction, Game Preview

Syracuse vs Wagner game preview, prediction, and breakdown for the Week 5 game on Saturday, October 1

Syracuse vs Wagner prediction, game preview, how to watch. Week 5, Saturday, October 1


Syracuse vs Wagner How To Watch

Date: Saturday, October 1
Game Time: 5:00 ET
Venue: JMA Wireless Dome, Syracuse, NY
How To Watch: ESPN+/ACC Network
Record: Syracuse (4-0), Wagner (0-3)
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Roundup: Overrated, Underrated, What it all Means
CFN 1-131 Rankings | Bowl Projections
What 12-Team Playoff Would Look Like
Hot Seat Coach Rankings after Week 4
Think, Know, Believe: Football Smack Talk
Contact/Follow @ColFootballNews & @PeteFiutak

Syracuse vs Wagner Game Preview

Why Wagner Will Win

The Seahawks might be having their share of issues, but they’re not screwing up.

Penalties aren’t an issue over the first three games, there hasn’t been a lost fumble, and the four interceptions are mostly because the offense has to keep throwing to try getting back in games.

Syracuse turned the ball over four times in the close win over Virginia, penalties have been a huge issue, and …

NFL Expert Picks, Week 4

Why Syracuse Will Win

Syracuse should be able to put this away fast.

Wagner has defensive problems on third down, the offense doesn’t do much of anything right, and scoring has been like pulling teeth with just seven points in each of the last two games and just ten points in the second half so far this year.

Syracuse will use this to tune up with a BRUTAL slate coming up next – NC State, at Clemson, Notre Dame at Pitt, Florida State, at Wake Forest …

– Schedules, Previews CollegeNFL

What’s Going To Happen

Get going, get the win, get the stars on the sidelines as soon as humanly possible.

The Orange won’t have to work too hard to get to 5-0, but they won’t do anything special after the first few drives.

The Seahawks will struggle to score against the Syracuse twos and threes – Rutgers beat them 66-7 a few weeks ago – and there won’t be any drama.

There are two weeks off before the ACC season kicks back in, so the Orange coaching staff will keep the main guys in for a half and coast from there.

CFN Expert Picks, Week 5

Syracuse vs Wagner Prediction, Line

Syracuse 55, Wagner 3
Line: Syracuse -55, o/u: 60
ATS Confidence out of 5: 1
Syracuse vs Wagner Must See Rating (out of 5): 1

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College Football Predictions, Schedule, Game Previews, Scoreboard: Week 5

College football predictions, schedule, game previews and TV listings for Week 5

College football schedule, predictions, game previews, lines, scoreboard, and TV listings for Week 5 of the season.


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Week 5 Schedules, Game Previews, Predictions
ACC | AAC | Big Ten | Big 12 | C-USA
IND | MAC | M-West | Pac-12 | SEC | Sun Belt
CFN Expert Picks: Week 5 
Click on each game for the preview and prediction

ACC College Football Schedule, Predictions, Lines: Week 5

Results So Far
Straight Up 39-8, ATS 21-24-2, o/u 35-11-1 

Saturday, October 1

Louisville at Boston College
12:00, ACC Network
Line: Louisville -15.5, o/u: 51

Wake Forest at Florida State
3:30, ABC
Line: Florida State -7, o/u: 64

Virginia Tech at North Carolina
3:30, ACC Network
Line: North Carolina -9.5, o/u: 51.5

Wagner at Syracuse
5:00, ACC Network/ESPN+
Line: Syracuse -55, o/u: 60

NC State at Clemson
7:30, ABC
Line: Clemson -6.5, o/u: 39.5

Virginia at Duke
7:30, ESPN3
Line: Duke -2.5, o/u: 49

Georgia Tech at Pitt
8:00, ACC Network
Line: Pitt -22, o/u: 49

Week 5 Schedules, Game Previews, Predictions
ACC | AAC | Big Ten | Big 12 | C-USA
IND | MAC | M-West | Pac-12 | SEC | Sun Belt
CFN Expert Picks: Week 5 

NEXT: American Athletic Conference College Football Schedule, Predictions, Lines: Week 5

Georgia Tech vs Pitt Prediction, Game Preview

Georgia Tech vs Pitt game preview, prediction, and breakdown for the Week 5 game on Saturday, October 1

Georgia Tech vs Pitt prediction, game preview, how to watch. Week 5, Saturday, October 1


Georgia Tech vs Pitt How To Watch

Date: Saturday, October 1
Game Time: 8:00 ET
Venue: Acrisure Stadium, Pittsburgh, PA
How To Watch: ACC Network
Record: Georgia Tech (1-3), Pitt (3-1)
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Roundup: Overrated, Underrated, What it all Means
CFN 1-131 Rankings | Bowl Projections
What 12-Team Playoff Would Look Like
Hot Seat Coach Rankings after Week 4
Think, Know, Believe: Football Smack Talk
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Georgia Tech vs Pitt Game Preview

Why Georgia Tech Will Win

Welcome to the Brent Key era at Georgia Tech.

The pressure is off, there’s no more speculation about the future of Geoff Collins or whether or not the direction of the program is changing – it is – and no the players can go out and just play.

So is this team doing anything right? The coach got canned four games in, so not really, but there’s a good enough pass rush to bother Kedon Slovis to keep him from getting comfortable.

On the offensive side, the running game that only busted out against Western Carolina has decent enough parts to be dangerous.

Lost in the rough start is that Clemson is good. Ole Miss is good. Going to UCF  is tough. The Yellow Jacket schedule wasn’t easy to start, and now Jeff Sims and the offense get to go against a pass defense that struggled against West Virginia and Tennessee, and …

NFL Expert Picks, Week 4

Why Pitt Will Win

The coaching change isn’t going to make the Georgia Tech pass defense better.

Slovis should do just fine with a wee bit of time. The Yellow Jackets were able to hold down UCF’s passing game that doesn’t do a whole lot, but Clemson’s DJ Uiagalelei and Jaxson Dart from Ole Miss were able to put up yards, even if it wasn’t always pretty.

Pitt has a bad mix of things that could take away what the offense wants to do.

The team is great at controlling the clock – Pitt is first in the ACC in time of possession, and Georgia Tech is last – with a pass rush that should live in the backfield.

However …

– Schedules, Previews CollegeNFL

What’s Going To Happen

The Georgia Tech offense might be more dangerous.

The one thing the coaching change might do is get Sims on the move more with a faster pace to the attack. The O should open it up a bit, take more shots down the field, and …

The Pitt defense will generate too much pressure and ruin most of those plans before they can get going.

The cold and the rain expected on Saturday night won’t help.

Georgia Tech – just like in the other three losses – will have way too hard of a time scoring.

CFN Expert Picks, Week 5

Georgia Tech vs Pitt Prediction, Line

Pitt 34, Georgia Tech 17
Line: Pitt -22, o/u: 49
ATS Confidence out of 5: 1.5
Georgia Tech vs Pitt Must See Rating (out of 5): 2

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Virginia vs Duke Prediction, Game Preview

Virginia vs Duke game preview, prediction, and breakdown for the Week 5 game on Saturday, October 1

Virginia vs Duke prediction, game preview, how to watch. Week 5, Saturday, October 1


Virginia vs Duke How To Watch

Date: Saturday, October 1
Game Time: 7:30 ET
Venue: Wallace Wade Stadium, Durham, NC
How To Watch: ESPN3
Record: Virginia (2-2), Duke (3-1)
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Roundup: Overrated, Underrated, What it all Means
CFN 1-131 Rankings | Bowl Projections
What 12-Team Playoff Would Look Like
Hot Seat Coach Rankings after Week 4
Think, Know, Believe: Football Smack Talk
Contact/Follow @ColFootballNews & @PeteFiutak

Virginia vs Duke Game Preview

Why Virginia Will Win

Eventually the offense will get going.

It’s been night-and-day different – that’s a nice way of saying awful – compared to the 2021 version that bombed away all over the place, but the parts are still in place to do a whole lot more.

Brennan Armstrong almost pulled out the Syracuse game last week – the Cavaliers lost 22-20 – and now he gets a Duke defense that failed miserably against the two teams on the schedule so far that can throw.

Northwestern threw for 435 yards against the Blue Devils, and Kansas star Jalon Daniels went off for 324 last week to go along with the team’s 213-yard ground game.

Armstrong is too good for the O – especially on third downs – to be this bad. Virginia is 118th in the nation in third down conversions, and Duke is dead last in the ACC in third down D.

Or …

NFL Expert Picks, Week 4

Why Duke Will Win

Maybe Virginia’s offense just isn’t very good.

The line is getting Armstrong beaten up, the running game hasn’t been able to take over when needed, and between the ten turnovers and the team’s 31 penalties, there are WAY too many mistakes.

Duke might not be perfect, but it’s not screwing up – the two turnovers so far weren’t any big deal.

The passing game has been effective because the O line leads the ACC in pass prediction, and …

– Schedules, Previews CollegeNFL

What’s Going To Happen

Can the Virginia pass rush be enough to get this done?

The offense isn’t playing well, but the defense has stepped up with a ton of sacks, the D forced four takeaways against both Illinois and Syracuse, and the offense should be able to finally move against a Blue Devil defense that clunked against the two Power Five teams on the slate.

There won’t be anything pretty about this. It’s supposed to be cold, rainy, and the wind is going to be a problem.

It’ll come down to defense and running game, and Virginia will be better in both areas.

CFN Expert Picks, Week 5

Virginia vs Duke Prediction, Line

Virginia 21, Duke 20
Line: Duke -2.5, o/u: 49
ATS Confidence out of 5: 1.5
Virginia vs Duke Must See Rating (out of 5): 2.5

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Clemson vs NC State Prediction, Game Preview

Clemson vs NC State game preview, prediction, and breakdown for the Week 5 game on Saturday, October 1

Clemson vs NC State prediction, game preview, how to watch. Week 5, Saturday, October 1


Clemson vs NC State How To Watch

Date: Saturday, October 1
Game Time: 7:30 ET
Venue: Memorial Stadium, Clemson, SC
How To Watch: ABC
Record: Clemson (4-0), NC State (4-0)
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Roundup: Overrated, Underrated, What it all Means
CFN 1-131 Rankings | Bowl Projections
What 12-Team Playoff Would Look Like
Hot Seat Coach Rankings after Week 4
Think, Know, Believe: Football Smack Talk
Contact/Follow @ColFootballNews & @PeteFiutak

Clemson vs NC State Game Preview

Why NC State Will Win

Devin Leary. Your table is ready.

The NC State quarterback pulled off the win over the Tigers last year with a brilliant 238-yard day with four touchdowns, but he has yet to get going against anyone good.

Oh sure, he took target practice against UConn and Charleston Southern, but he struggled against East Carolina and only hit the short-range throws against Texas Tech.

Clemson has an NFL defensive front, and the offense has started to put it all together, but the secondary is getting ripped.

Furman threw too easily, Louisiana Tech bombed away for over 300 yards, and Sam Hartman earned himself a job in some NFL team’s quarterback room with a 337-yard, six-touchdown day last week.

The Wolfpack defense has been every bit the wall it was expected to be. It came up with four takeaways in the 27-14 win over Texas Tech, the secondary has seven picks on the year, and the run defense is holding up well.

On the other side, the offensive line has been great in pass protection giving Leary time, but …

NFL Expert Picks, Week 4

Why Clemson Will Win

DJ Uiagalelei is starting to ball out.

He has been much maligned for not being consistent, the offense not moving well enough, and for not being likely-star-in-waiting Cade Klubnik, but the team needed him to show up against Wake Forest and he came through large.

For all the slings and arrow, he’s hitting 64% of his passes for 1,033 yards and ten scores with just one pick – and with 169 yards and a rushing score – in four games.

Now it’s redemption time.

Leary was fantastic, the NC State defense was great, and Clemson still almost won last year even though Uiagalelei had an awful day in the 27-21 double overtime loss.

The offensive line has been good enough in pass protection, the running game has been solid, and the Clemson defensive front seven is the Clemson defensive front seven.

The secondary might be having issues, but the defensive line isn’t allowing much of anything on the ground and it’s making a slew of plays in the backfield.

– Schedules, Previews CollegeNFL

What’s Going To Happen

The Clemson defense is going to get it done in what should be lousy conditions. It’s not supposed to be too bad by game time, but it’ll definitely be wet out.

Leary will be good against the struggling Clemson secondary, but for the first time this year the running game will have to deal with a brick wall of a defensive front.

For all of Clemson’s sputters and coughs on offense, it’s not turning the ball over enough to matter.

No, the O won’t be held to 215 yards of total offense this time around. It won’t go off, but it’ll be good enough to let the defense take care of the rest.

CFN Expert Picks, Week 5

Clemson vs NC State Prediction, Line

Clemson 27, NC State 23
Line: Clemson -6.5, o/u: 39.5
ATS Confidence out of 5: 2
Clemson vs NC State Must See Rating (out of 5): 5

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North Carolina vs Virginia Tech Prediction, Game Preview

North Carolina vs Virginia Tech game preview, prediction, and breakdown for the Week 5 game on Saturday, October 1

North Carolina vs Virginia Tech prediction, game preview, how to watch. Week 5, Saturday, October 1


North Carolina vs Virginia Tech How To Watch

Date: Saturday, October 1
Game Time: 3:30 ET
Venue: Kenan Stadium, Chapel Hill, NC
How To Watch: ACC Network
Record: North Carolina (3-1), Virginia Tech (2-2)
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Roundup: Overrated, Underrated, What it all Means
CFN 1-131 Rankings | Bowl Projections
What 12-Team Playoff Would Look Like
Hot Seat Coach Rankings after Week 4
Think, Know, Believe: Football Smack Talk
Contact/Follow @ColFootballNews & @PeteFiutak

North Carolina vs Virginia Tech Game Preview

Why Virginia Tech Will Win

So what’s going right with the Hokies?

It’s going to be a process before things start to come together under new head coach Brent Pry, but the defense hasn’t been bad.

West Virginia was balanced and moved with ease in the 33-10 win last week, but overall the Hokie D has been great on third downs, the secondary has been solid, and the 218 rushing yards by the Mountaineers was the first time this year anyone has been able to move on the ground.

On the flip side, the North Carolina run defense has been abysmal. Everyone is getting fat running on the Tar Heels with Appalachian State, Georgia State, and Notre Dame combining for close to 800 rushing yards with six scores.

Virginia Tech hasn’t been able to run well so far, but it has to try.

NFL Expert Picks, Week 4

Why North Carolina Will Win

Yeah, Virginia Tech’s defense has technically been okay so far, but playing Old Dominion, Boston College, and Wofford had something to do with that.

The North Carolina defense might not know the season has started, but the offensive side is rolling with ease, it’s averaging 47 points per game, and it’s averaging over 500 yards per game.

Get up fast, make Virginia Tech have to crank up the passing game, and all should be fine. Hokie QB Grant Wells might put up some yards, but the offense isn’t converting off the decent drives.

– Schedules, Previews CollegeNFL

What’s Going To Happen

Can North Carolina finally have an easy game against an FBS team?

It’s the team’s own fault for not being able to do enough defensively, but Virginia Tech doesn’t have the pop to do much once the scoring starts rolling.

The Tar Heels will rely mostly on the ground game to start, and then Drake Maye and the passing attack will take over as the Hokie D gets picked apart.

CFN Expert Picks, Week 5

North Carolina vs Virginia Tech Prediction, Line

North Carolina 34, Virginia Tech 24
Line: North Carolina -9.5, o/u: 51.5
ATS Confidence out of 5: 3
North Carolina vs Virginia Tech Must See Rating (out of 5): 2

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Florida State vs Wake Forest Prediction, Game Preview

Florida State vs Wake Forest game preview, prediction, and breakdown for the Week 5 game on Saturday, October 1

Florida State vs Wake Forest prediction, game preview, how to watch. Week 5, Saturday, October 1


Florida State vs Wake Forest How To Watch

Date: Saturday, October 1
Game Time: 3:30 ET
Venue: Doak Campbell Stadium, Tallahassee, FL
How To Watch: ABC
Record: Florida State (4-0), Wake Forest (3-1)
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Roundup: Overrated, Underrated, What it all Means
CFN 1-131 Rankings | Bowl Projections
What 12-Team Playoff Would Look Like
Hot Seat Coach Rankings after Week 4
Think, Know, Believe: Football Smack Talk
Contact/Follow @ColFootballNews & @PeteFiutak

Florida State vs Wake Forest Game Preview

Why Wake Forest Will Win

Sam Hartman almost pulled it off.

Clemson is Clemson – it had the defense and it had the guys to pull off the 51-45 win last week over the Demon Deacons – but Hartman balled out with his third straight 300-yard game since returning from the blood clot issue and hit the Tigers for six touchdown passes and a slew of deep plays.

Florida State hasn’t seen anything like Hartman and the Wake Forest passing game.

Jayden Daniels was able to hit the midrange passes in LSU’s loss to the Noles, and he almost pulled off the win with a late rally. Louisville’s Malik Cunningham threw for 243 yards, and even Boston College’s dying offense was able to connect on a slew of short range throws.

Florida State has to get ready to crank up the offense, but …

NFL Expert Picks, Week 4

Why Florida State Will Win

Can the Wake Forest defense hold up?

The pass rush is good, and the run defense hasn’t been too bad, but DJ Uiagalelei came up with a terrific passing day for Clemson. Now it’s Jordan Travis’s turn.

He might not be the flashiest of quarterbacks in a huge year for the position, but the veteran has been accurate, he’s coming up with the explosive downfield plays, and his team is 4-0 after he bombed away for over 300 yards in the 44-14 win over Boston College.

As good as Travis is, the FSU passing game isn’t going to be able to keep up yard for yard with what Hartman brings, but it’s the rushing attack that should take over.

– Schedules, Previews CollegeNFL

What’s Going To Happen

The Seminoles lead the ACC in rushing, they’re great at controlling the ball and the tempo, and they’ll have the O on the field for over 35 minutes.

And the weather? After so much worry and concern about Hurricane Ian pummeling Tallahassee, it shifted away. It’s going to be in the mid-80s with minimal wind and little chance of rain.

The conditions will be perfect for a shootout. Florida State will come up with more from the running game to take over late in the thriller.

CFN Expert Picks, Week 5

Florida State vs Wake Forest Prediction, Line

Florida State 45, Wake Forest 40
Line: Florida State -7, o/u: 64
ATS Confidence out of 5: 2
Florida State vs Wake Forest Must See Rating (out of 5): 4.5

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Louisville vs Boston College Prediction, Game Preview

Louisville vs Boston College game preview, prediction, and breakdown for the Week 5 game on Saturday, October 1

Louisville vs Boston College prediction, game preview, how to watch. Week 5, Saturday, October 1


Louisville vs Boston College How To Watch

Date: Saturday, October 1
Game Time: 12:00 ET
Venue: Alumni Stadium, Chestnut Hill, MA
How To Watch: ACC Network
Record: Louisville (2-2), Boston College (1-3)
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Roundup: Overrated, Underrated, What it all Means
CFN 1-131 Rankings | Bowl Projections
What 12-Team Playoff Would Look Like
Hot Seat Coach Rankings after Week 4
Think, Know, Believe: Football Smack Talk
Contact/Follow @ColFootballNews & @PeteFiutak

Louisville vs Boston College Game Preview

Why Louisville Will Win

If you’re going to be a pass-only offense, you need to be able to pass.

Boston College doesn’t do the whole running thing – averaging just under 60 yards per game – but the passing attack isn’t making up for it.

The team has playmakers in QB Phil Jurkovec and WR Zay Flowers, but there’s no downfield passing attack for an offense that’ struggling to get to 20 points to go along with an ACC-worst 283 yards per game.

The Louisville defense is coming off one of its best performances of the season in a 41-3 win over USF, and it’s not going to allow anything against the run.

Boston College can’t pass protect, Louisville is among the best in the country at getting to the quarterback, and …

NFL Expert Picks, Week 4

Why Boston College Will Win

Jurkovec might be able to dink and dunk on the Cardinals to death.

UCF and USF struggled to complete the basic passes, but Syracuse’s Garrett Shrader and Florida State’s combination of Jordan Travis and Tate Rodemaker were able to combine to hit 70% of their throws for 266 yards and four scores.

No, the Boston College offense isn’t working, but Jurkovec should be able to make just enough easy throws to keep things moving.

Considering the overall struggles, the Eagles have to own the mistake battle. They need to be +2 in turnover margin, and at least +4 in penalties.

– Schedules, Previews CollegeNFL

What’s Going To Happen

What about Boston College would suggest that it’s ready to pull off a good win?

It couldn’t do anything against a bad Virginia Tech team, and it couldn’t get going against Rutgers or Florida State.

Louisville has a whole slew of problems, but it should be able to run without too many problems on the BC front, and the defense will do its part. The team wins when the D is okay.

The Louisville D will be okay.

CFN Expert Picks, Week 5

Louisville vs Boston College Prediction, Line

Louisville 31, Boston College 17
Line: Louisville -15.5, o/u: 51
ATS Confidence out of 5: 1.5
Louisville vs Boston College Must See Rating (out of 5): 2

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