Notre Dame Fighting Irish betting odds line spread pick predictions best bets – Page 4

North Carolina at Notre Dame odds, picks and predictions

Analyzing Wednesday’s North Carolina at Notre Dame odds and lines, with college basketball expert picks, predictions and best bets.

The North Carolina Tar Heels (16-11, 8-8 ACC) face the Notre Dame Fighting Irish (10-17, 2-14) in South Bend Wednesday at 9 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the North Carolina vs. Notre Dame odds, and make our expert college basketball picks, predictions and bets.

This will be a rematch of an 81-64 home win for the Tar Heels as 12-point favorites on Jan. 7. Since then, both teams have struggled.

UNC is 5-6 since beating the Irish and is 1-5 in February. It has lost its last 2 games by 8 points each to Miami and N.C. State after defeating Clemson by 20 on Feb. 11.

Notre Dame is on a 5-game losing streak and is 2-9 since the loss to UNC. Despite the losses, the Irish have been keeping games close. Only 1 of the 5 losses in the current streak was by more then 6 points and despite their struggles, Notre Dame is 10-7 at home. UNC is 2-7 on the road.

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North Carolina at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 10:51 a.m. ET.

Moneyline (ML): North Carolina -290 (bet $290 to win $100) | Notre Dame +210 (bet $100 to win $210)
Against the spread (ATS): North Carolina -6.5 (-105) | Notre Dame +6.5 (-115)
Over/Under (O/U): 148.5 (O: -105 | U: -115)

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North Carolina at Notre Dame picks and predictions

Prediction

North Carolina 73, Notre Dame 68

Moneyline

PASS.

UNC on the moneyline might just be the safest play in this game. The spread is tough and so is the total. But I am not willing to risk -290 to bet on it. Nor should you. If you want to make a play on this number, add it in as part of a larger parlay to get better value.

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Against the spread

NOTRE DAME +6.5 (-115).

Only 1 of Notre Dame’s last 5 losses would have been larger than this spread.

All the trends favor Notre Dame. UNC is 1-6 ATS in its last 7 overall games, 1-10-1 ATS in its last 12 road games against teams with winning home records and are 0-7 ATS in its last 7 Wednesday games.

The Tar Heels have not been covering and they will fail to do so again Wednesday on the road.

Over/Under

UNDER 148.5 (-115).

Both teams come into this game struggling to score. UNC has gone Under in 5 of its last 6 road games. Notre Dame is 7-1-1 to the Under in its last 9 games following an ATS victory.

Both UNC and Notre Dame are terrible on defense. UNC ranks 261st at 72.6 points per game while Notre Dame is 247th at 72 PPG. It will not matter in this game as both will find it difficult to find the basket and the 148.5 number will not be threatened. As long as this total stays above 145.5, I like the Under.

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Notre Dame at Duke odds, picks and predictions

Analyzing Tuesday’s Notre Dame at Duke odds and lines, with college basketball expert picks, predictions and best bets.

The Notre Dame Fighting Irish (10-15, 2-12 ACC) and Duke Blue Devils (17-8, 8-6) meet Tuesday at Cameron Indoor Stadium in Durham, N.C. Tip-off is scheduled for 7 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Notre Dame vs. Duke game odds, and make our expert college basketball picks, predictions and bets.

Notre Dame has been in a tailspin in coach Mike Brey’s final season at the helm, although it was reported he won’t be officially retiring after his tenure with the Fighting Irish. ND has dropped 3 games in a row, and 7 of its last 8, while going just 4-14 against the spread (ATS) across the past 18 games overall.

Duke had posted 3 straight impressive wins from Jan. 28-Feb. 4, including a win in the Battle of the Blues over rival North Carolina, but it has suffered back-to-back losses on the road at Miami and Virginia. The Blue Devils are also just 3-11 ATS in the past 14 games overall, so something’s gotta give.

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Notre Dame at Duke odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:43 a.m. ET.

Moneyline (ML): Notre Dame +500 (bet $100 to win $500) | Duke -800 (bet $800 to win $100)
Against the spread (ATS): Notre Dame +11.5 (-105) | Duke -11.5 (-115)
Over/Under (O/U): 140.5 (O: -110 | U: -110)

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Notre Dame at Duke picks and predictions

Prediction

Duke 75, Notre Dame 67

Moneyline

PASS.

Duke (-800) is way too expensive, even to include in a parlay. Focus on the spread or total in this game instead.

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Against the spread

NOTRE DAME +11.5 (-105) is worth the play, as the 2023 version of Duke has been mediocre at best and has no business laying double digits against anyone right now.

The last time Duke laid double digits was New Year’s Eve against Florida State, covering in a win. However, it is just 1-4 ATS in the past 5 games overall when laying 10 or more points.

Over/Under

OVER 140.5 (-115) is the lean, but play it lightly.

The Over has been the dominant side for the Fighting Irish of late, going 8-1-2 in the past 11 games overall and cashing at an 18-7-1 clip in the past 26 games on the road.

The Over is also 20-7-2 in the past 29 home games for Duke when facing a team with a losing road record.

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Florida State at Notre Dame odds, picks and predictions

Analyzing Tuesday’s Florida State at Notre Dame odds and lines, with college basketball expert picks, predictions and best bets.

The Florida State Seminoles (5-13, 3-4 ACC) battle the Notre Dame Fighting Irish (9-9, 1-6) Tuesday. Tip from Purcell Pavilion is set for 7 p.m. ET (ESPNU). Below, we analyze Tipico Sportsbook’s lines around the Florida State vs. Notre Dame odds, and make our expert college basketball picks, predictions and bets.

Florida State lost 67-58 to Virginia Saturday, but covered as a 10-point home underdog. The Seminoles are 8-10 against the spread (ATS) on the season and 0-4 straight up in true road games. They have, however, covered 7 of their last 10 games.

Notre Dame lost to Syracuse 78-73 Saturday, winning outright as a 5.5-point road underdog. The Fighting Irish are 4-14 ATS on the season yet are 9-3 straight up at home. They are 2-8 ATS over their last 10 games and 1-4 ATS over their last 5. Notre Dame ranks 38th in the nation in 3-point shooting (37.9%).

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Florida State at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:32 a.m. ET.

Moneyline (ML): Off the board (OTB)
Against the spread (ATS): Florida State +4.5 (-105) | Notre Dame -4.5 (-115)
Over/Under (O/U): 140.5 (O: -110 | U: -110)

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Florida State at Notre Dame picks and predictions

Prediction

Notre Dame 74, Florida State 71

Moneyline

This game was OTB at the time of publishing, but both sides will likely be lacking value when it does open.

PASS.

Against the spread

BET FLORIDA STATE +4.5 (-105).

FSU won 73-72 at home when these teams met on Dec. 21, winning outright as a 2-point underdog. Notre Dame lost yet despite that it shot 51% from the field and 47% from deep, respectively 4% and 15% better than Florida State.

Those should even out, and making up for the difference in location, this game should again be a close battle. The Fighting Irish are just 1-4 ATS over their last 5, losing 4 of those games outright and failing to cover as a favorite in 2.

Considering the Fighting Irish’s lacking play as of late and how the first round went, back FLORIDA STATE +4.5 (-105).

Over/Under

LEAN OVER 140.5 (-110).

Notre Dame has gone Over in 4 straight games, and it has a lacking defense, ranking 327th in opponents’ field goal percentage (46.2%). It has allowed 70 or more points to its opponent in 5 straight games. Notre Dame is 5-2 O/U in conference games.

Florida State is 3-4 O/U in conference games and has gone Over in 4 of its last 6 games. FSU has scored 75 or more in 2 of its last 3. Put it all together and back the OVER 140.5 (-110).

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Notre Dame at North Carolina odds, picks and predictions

Analyzing Saturday’s Notre Dame at North Carolina odds and lines, with college basketball expert picks, predictions and best bets.

The Notre Dame Fighting Irish (8-7, 0-4 ACC) battle the North Carolina Tar Heels (10-5, 2-2) Saturday. Tip from the Dean Smith Center is set for 11:30 a.m. ET (ESPN2). Below, we analyze Tipico Sportsbook’s lines around the Notre Dame vs. North Carolina odds, and make our expert college basketball picks, predictions and bets.

North Carolina took down Wake Forest 88-79 Wednesday but failed to cover as a 10-point home favorite. The Tar Heels are just 4-10-1 against the spread (ATS) this season. They are a perfect 7-0 straight up at home though. North Carolina has failed to cover 3 straight but is 3-3 ATS over its last 6. UNC ranks 24th in the nation in points per game (81.4).

Notre Dame was upset as a 2.5-point road favorite at Boston College 70-63 Tuesday. The Fighting Irish are only 3-12 ATS, including 2-8 ATS over their last 10. Notre Dame’s strength is shooting from deep, ranking 43rd in 3-point field-goal percentage (37.7%), according to Covers.com.

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Notre Dame at North Carolina odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 11:47 p.m. ET.

Moneyline (ML): Notre Dame +525 (bet $100 to win $525) | North Carolina -850 (bet $100 to win $850)
Against the spread: Notre Dame +12.5 (-110) | North Carolina -12.5 (-110)
Over/Under (O/U): 144.5 (O: -110 | U: -110)

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Notre Dame at North Carolina picks and predictions

Prediction

North Carolina 78, Notre Dame 71

Moneyline

PASS.

North Carolina’s -850 price is way too risky even with UNC being 8-0 at home and Notre Dame 0-2 on the road (not counting neutral-site games). A North Carolina (-850) moneyline is unplayable, even in a parlay.

Against the spread

LEAN NOTRE DAME +12.5 (-110).

North Carolina is just 3-4 ATS at home this season and has failed to cover 3 in a row, 1 of which was at home (the 9-point win over Wake Forest). The Tar Heels are just 3-6-1 ATS over their last 10, so they haven’t been defeating opponents by as much as books would think lately.

As for the Fighting Irish, they have been awful ATS as well, posting just a 3-12 record. However, they do hold opponents to 31.8% from deep, and the Tar Heels have snipers.

With a spread of this size in a conference game, BACK NOTRE DAME +12.5 (-110) to limit their opponents’ 3-point shooting and keep the game reasonably close.

Over/Under

BET OVER 144.5 (-110).

While Notre Dame should be able to slow down North Carolina’s shooters, it ranks 316th in opponents’ field-goal percentage at 46.1% (according to NCAA.org). So, the high-octane Tar Heels attack mixed with the Fighting Irish’s overall defensive inefficiencies should be the perfect combination for points to be scored and the Over to cash.

The Fighting Irish score 69.7 points per game as well, so they hold their own offensively. They’ve gone Over in 3 of their last 5. North Carolina has gone Over in 5 straight and is 9-6 O/U this season.

Ultimately, OVER 144.5 (-110) is my FAVORITE BET in this contest.

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Miami at Notre Dame odds, picks and predictions

Analyzing Friday’s Miami at Notre Dame odds and lines, with college basketball expert picks, predictions and best bets.

The No. 16 Miami Hurricanes (12-1, 3-0 ACC) visit Notre Dame (8-5, 0-2) Friday. Tip from Purcell Pavilion is set for 2 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Miami vs. Notre Dame odds, and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the USA TODAY Sports Coaches Poll.

Miami beat Virginia 66-64 on Dec. 20 when it last took the court, winning outright as a 3.5-point home underdog. The Hurricanes are 7-6 against the spread (ATS) and 9-0 straight up at home. Miami has covered 5 of its last 7. It has seen success behind a highly efficient attack, knocking down 48.1% of its field goal attempts (46th in the nation).

Notre Dame took down Jacksonville 59-43 at home Tuesday, covering as 8.5-point home favorites. The Fighting Irish are just 3-10 ATS this season and save covered just 1 of their last 6 games. However, they are a strong 8-2 straight up at home. Notre Dame’s strength is when it can get to the line, ranking 6th in the nation in free-throw percentage (79.7%).

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Miami at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9 a.m. ET.

Moneyline (ML): Miami -150 (bet $150 to win $100) | Notre Dame +125 (bet $100 to win $125)
Against the spread (ATS): Miami -3.5 (+100) | Notre Dame +3.5 (-120)
Over/Under (O/U): 144.5 (O: -105 | U: -115)

Miami at Notre Dame picks and predictions

Prediction

Miami 74, Notre Dame 68

Moneyline

PASS.

Miami (-150) is 9-0 at home, but anything can happen in ACC play. This line has moved down a bit, but I still don’t feel like there is enough value here.

Against the spread

BET MIAMI -3.5 (-110).

Miami has covered 5 of its last 7 and is an impressive 12-1 straight up this season. It has shown it is worth playing it to win by 4 — only has 2 of its 12 wins by fewer than 4 points this season.

Notre Dame may have covered its last game but has been awful for bettors this season with just a 3-10 ATS record.

The Fighting Irish have failed to cover 5 of their last 6. They also didn’t cover their lone road game, a 73-72 loss at Florida State, closing as 2-point road favorites.

Back MIAMI -3.5 (-110).

Over/Under

LEAN UNDER 144.5 (-115).

Both teams have played more to the Under this season. Miami is 5-8 O/U with Notre Dame 6-7 O/U. The Fighting Irish have gone Under in 7 of their last 10.

Miami has gone Under in its last 2 ACC games and in 6 of its last 8 overall.

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Gator Bowl: South Carolina vs. Notre Dame odds, picks and predictions

Analyzing Friday’s South Carolina vs. Notre Dame Gater Bowl odds and lines, with college football expert picks, predictions and best bets.

The No. 19 South Carolina Gamecocks (8-4) take on the No. 20 Notre Dame Fighting Irish (8-4) Friday. Kickoff from TIAA Bank Field in Jacksonville is at 3:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the South Carolina vs. Notre Dame odds, and make our expert college football picks and predictions.

Rankings courtesy of AFCA Coaches Poll powered by USA TODAY sports

After a strong start to his tenure in 2021, coach Shane Beamer has had an even better season in 2022 for the Gamecocks. South Carolina is in a 2nd straight bowl game with transfer QB Spencer Rattler leading the offense. Few Gamecocks will be unable to play in this game other than their top 2 TE, and this gives them an advantage over the Irish who will be without star TE Michael Mayer.

Notre Dame will not only be without Mayer as starting QB Drew Pine has decided to transfer and will not play. The Irish are forced to turn to QB Tyler Buchner, who began 2022 as their starter but was sidelined by a shoulder injury that required surgery. He will be rusty and, with Mayer out, will have few options on the offensive side to count on in this game.

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South Carolina vs. Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 1:30 p.m. ET.

Moneyline (ML): South Carolina +135 (bet $100 to win $135) | Notre Dame -155 (bet $155 to win $100)
Against the spread (ATS): South Carolina +3 (-109) | Notre Dame -3 (-111)
Over/Under (O/U): 50.5 (O: -111 | U: -109)

South Carolina vs. Notre Dame picks and predictions

Prediction

South Carolina 24, Notre Dame 20

Moneyline

BET SOUTH CAROLINA (+135).

South Carolina will have a fuller complement of weapons while Notre Dame will be without Pine and Mayer, and this will make all the difference

This will be a lower-scoring affair but South Carolina will prevail and taking them on the moneyline is my favorite play in this game.

Against the spread

PASS.

Stick with the better value on the South Carolina moneyline.

Over/Under

BET UNDER 50.5 (-109).

The Irish will struggle to keep up their end of the bargain with their missing weapon, and the defense for the Irish is good and will be able to hold down the Gamecocks. Both teams scoring in the low 20s should be expected, and we’re more likely to see the UNDER 50.5 (-109) connect than we are to see Buchner knock off the rust after missing 4 months.

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Notre Dame vs. Georgia odds, picks and predictions

Analyzing Sunday’s Notre Dame vs. Georgia odds and lines, with college basketball expert picks, predictions and best bets.

The Notre Dame Fighting Irish (7-3) will travel to Atlanta to take on the Georgia Bulldogs (7-3) Sunday at 5:30 p.m. ET (ESPN2). Below, we analyze Tipico Sportsbook’s lines around the Notre Dame vs. Georgia odds, and make our expert college basketball picks, predictions and bets.

After a week off to think about it, Notre Dame finally plays another game after being beaten 79-64 at home against Marquette last Sunday. The Irish have only played once away from their home court this season, a 63-51 loss to St. Bonaventure. Sunday’s neutral site game, only 75 miles from the Georgia campus, will be another tricky game for Notre Dame to avoid a 3rd loss in its last 4 games.

Georgia, in its 1st season under Michael White after firing Tim Crean last season, has started out strong. But the SEC road ahead will be difficult. This is not the football field and Georgia will not have more talent than the other schools. In this game, the Bulldogs will be the undermanned team. Georgia last played on Dec. 4, a 79-77 loss to Georgia Tech, although they covered as 4.5-point underdogs.

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Notre Dame vs. Georgia odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:34 a.m. ET.

Moneyline (ML): Notre Dame -160 (bet $160 to win $100) | Georgia +130 (bet $100 to win $130)
Against the spread (ATS): Notre Dame -3.5 (-105) | Georgia +3.5 (-115)
Over/Under (O/U): 133.5 (O: -110 | U: -110)

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Notre Dame vs. Georgia picks and predictions

Prediction

Notre Dame 64, Georgia 59

Moneyline

PASS.

Despite losing 2 of 3, Notre Dame is the better squad in this game. A-160 line is alright as part of a parlay, but for making a straight wager, it is just a bit too high.

Against the spread

BET NOTTRE DAME -3.5 (-105).

Notre Dame is rested and ready to go. After a 15-point loss to Marquette on Sunday and a 1-point loss to Syracuse, the Irish will look to get back on track in a game against a middling SEC team with some hope of making the NCAA Tournament. Notre Dame is better. They will show it here as they take care of the Bulldogs and the -3.5 (-115) spread.

Over/Under

BET UNDER 133.5 (-110).

Neither of these teams are offensive juggernauts. Both are 4-6 going Over in their games this season. This game will be like Saturday’s Houston-Virginia game in which 2 defensive minded teams played to a final of 69-61. These 2 teams are not as talented and the score may even be a bit lower. That game finished with a total of 113.5. This one is a full 20 points higher, which is too much of a cushion. Under 133.5 (-110) is my favorite play.

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Marquette at Notre Dame odds, picks and predictions

Analyzing Sunday’s Marquette at Notre Dame odds and lines, with college basketball expert picks, predictions and best bets.

The Marquette Golden Eagles (7-3) travel to South Bend to take on the Notre Dame Fighting Irish (7-2) Sunday at 4 p.m. ET (ESPN2). Below, we analyze Tipico Sportsbook’s lines around the Marquette vs. Notre Dame odds, and make our expert college basketball picks, predictions and bets.

Despite being less than 300 miles apart, these 2 schools have not met on the court since 2013.

After demolishing Baylor 96-70 on Nov. 29, the Golden Eagles have been less then stellar. They lost 80-77 at home to Wisconsin as a favorite on Dec. 3 and then did not cover as 18.5-point favorites in a 90-78 win against North Carolina Central on Tuesday.

The Fighting Irish were a slight underdog when they beat Michigan State 70-52 on Nov. 30, but then lost as a 6.5-point favorites to a bad Syracuse team 62-61 and failed to cover as 14-point favorites against an overmatched Boston University, winning 81-75.

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Marquette at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:45 a.m. ET.

Moneyline (ML): Marquette -125 (bet $125 to win $100) | Notre Dame +105 (bet $100 to win $105)
Against the spread (ATS): Marquette -1.5 (-105) | Notre Dame +1.5 (-115)
Over/Under (O/U): 145.5 (O: -105 | U: -115)

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Minnesota at Purdue picks and predictions

Prediction

Marquette 75, Notre Dame 68

Moneyline

PASS.

If you feel Notre Dame will win, this is the way to wager. Marquette is better and despite being on the road, will win and cover. Therefor passing on the ML is the way to play this game.

Against the spread

BET MARQUETTE -1.5 (-105).

Marquette plays to its opponents. It beat Baylor by 26 and lost by 3 to Wisconsin. Notre Dame is the opposite. They beat the teams they should and lose to the better teams like Marquette.

With this game being in South Bend, this could backfire. But I like Marquette to cover -1.5 by quite a bit here. This is my favorite play in this game.

Over/Under

BET UNDER 145.5 (-115)

Combined this season, these 2 teams are 10-8-1 to the Over. But this game will be a bit different with both playing keep-away for parts of this game. There may be some streaks of points, but there will also be far too many dry spells for this game to confidently go over. This is not a strong play for me. But 145.5 is just slightly too high to make a confident play on. So, I will instead go Under 145.5 (-115).

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Michigan State at Notre Dame odds, picks and predictions

Analyzing Wednesday’s Michigan State at Notre Dame odds and lines, with college basketball expert picks, predictions and best bets.

The Michigan State Spartans (5-2) and Notre Dame Fighting Irish (5-1) meet Wednesday in South Bend. Tip time at Purcell Pavilion will be at 9:15 p.m. ET (ESPN2). Below, we analyze Tipico Sportsbook’s lines around the Michigan State vs. Notre Dame odds, and make our expert college basketball picks, predictions and bets.

Michigan State snuck by Portland 78-77 in a Sunday game of the Phil Knight Invitational. The favored-by-6.5 Spartans were undone by 14 3-pointers in the win over the Pilots. The against-the-spread (ATS) loss marked MSU’s 3rd in its last 4 games.

The Fighting Irish last played Friday, dropping a 63-51 decision to St. Bonaventure. UND’s 51 points marked a season low.

The game is part of the ACC/Big Ten Challenge. Michigan State and Notre Dame last met on Nov. 28, 2020, when the Spartans topped the Irish 80-70.

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Michigan State at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:44 p.m. ET.

Moneyline: Michigan State -125 (bet $125 to win $100) | Notre Dame +105 (bet $100 to win $105)
Against the spread (ATS): Michigan State -1.5 (-115) | Notre Dame +1.5 (-105)
Over/Under (O/U): 139.5 (O: -115 | U: -105)

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Michigan State at Notre Dame picks and predictions

Prediction

Michigan State 70, Notre Dame 64

Moneyline

MSU is the superior defensive and rebounding team in this matchup. This game is a jump in class for the Irish, and the Notre Dame shooting numbers (56% effective field goal) are suspect and likely due some regression.

The Spartans’ performances the last few weeks, even in their loss to Alabama last Thursday, spell a team that can be pegged as a 60% proposition in this game. And that makes for value on Michigan State -125. But at the current prices, many bettors may not want to spend 15 cents for a point (vs. the -1.5 ATS action below). So PASS unless prices change.

Against the spread

The Fighting Irish are 1-6 ATS in their last 7 home games. Notre Dame figures to be in a fade spot here.

TAKE MICHIGAN STATE -1.5 (-115).

Over/Under

These teams player slow-tempo ball, and we can expected a game flow not overly infused with turnovers, 2nd-chance points, and free throws.

PLAY THE UNDER 139.5 (-105).

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Notre Dame at USC odds, picks and predictions

Analyzing Saturday’s Notre Dame at USC odds and lines, with college football expert picks, predictions and best bets.

The Notre Dame Fighting Irish (8-3) visit the USC Trojans (10-1) Saturday at 7:30 p.m. ET (ABC). Below, we analyze Tipico Sportsbook’s lines around the Notre Dame vs. USC odds, and make our expert college football picks and predictions.

USC is No. 5 in the AFCA Coaches Poll powered by USA TODAY sports, while Notre Dame is No. 15. The Trojans are No. 6 in the College Football Playoff Rankings.

In what started off as a promising year under 1st-year coach Marcus Freeman, Notre Dame lost its first 2 games, falling to Ohio State and Marshall. Along with a season-ending injury to QB Tyler Buchner, the Irish were behind the 8-ball heading into the rest of their season. A 16-14 loss to visiting Stanford Oct. 15 ended any hope Notre Dame had to make a New Year’s 6 Bowl. Now, the Irish would like nothing better than to knock the Trojans out of playoff contention in this traditional rivalry in the final week of the regular season.

USC kept its playoff hopes alive with a 48-45 comeback win on the road as a 2-point favorite against then-No. 16 UCLA last weekend. The Trojans trailed 14-0 after 1 quarter and 24-20 early in the 3rd before mounting the comeback behind QB Caleb Williams (470 passing yards, 2 passing TDs, 1 rushing TD) and a finally healthy WR Jordan Addison (11 catches, 178 yards, 1 TD). Williams and Addison should have a big night Saturday as Notre Dame doesn’t have the secondary to stop them.

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Notre Dame at USC odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday 2:49 a.m. ET.

Moneyline (ML): Notre Dame +170 (bet $100 to win $170) | USC -210 (bet $210 to win $100)
Against the spread (ATS): Notre Dame +5 (-109) | USC -5 (-111)
Over/Under (O/U): 64.5 (O: -111 | U: -109)

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Notre Dame at USC picks and predictions

Prediction

USC 45, Notre Dame 29

Moneyline

PASS.

USC (-210) has all the motivation it should need in this game with a chance to make the College Football Playoffs. A loss would wipe out any hope of doing so.

USC will prevail, but the -210 price is too high. I could see adding it to a multi-team parlay, however.

Against the spread

BET USC -5 (-111).

USC has a dreadful defense. It was bad in 2021 and under new defensive coordinator Alex Grinch and it has not improved in 2022. But the offense is great and can put up points. It put up 48 against UCLA Saturday only a week after putting up 55 against Colorado. Notre Dame, with Drew Pyne at QB, does not have the horses to keep up.

The Irish scored a 44-0 shutout victory over visiting Boston College last Saturday, covering as 19.5-point favorites. But BC was missing its top 6 offensive linemen due to injury. USC is not Boston College and Notre Dame’s 5-game win streak stops Saturday in the Coliseum.

Over/Under

BET OVER 64.5 (-111).

It is simple. USC can score, but it also can’t stop other teams from scoring. This means a lot of points to be had in this matchup and 64.5 is just too low.

This number is likely to jump before game time. If it stays under 67.5, I like it. OVER 64.5 (-111) is my FAVORITE PLAY in this game.

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If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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