New York Giants at New England Patriots odds, picks and prediction

Analyzing Thursday’s New York Giants at New England Patriots odds and lines, with expert NFL picks, predictions and best bets.

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The New York Giants and New England Patriots meet in their preseason opener Thursday. Kickoff from Gillette Stadium is set for 7 p.m. ET (NFL Network). Below, we analyze Tipico Sportsbook‘s lines around the Giants vs. Patriots odds, and make our best NFL picks, predictions and bets.

The Giants aren’t likely to play QB Daniel Jones and the starting offense much in this one. He and RB Saquon Barkley have been injury prone, and the weather forecast calls for potential showers and storms with breezy conditions.

The Patriots won all 3 of their preseason games last season, including a visit to the Meadowlands against the Giants. New England should be able to spoil head coach Brian Daboll’s preseason debut.

Giants at Patriots odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at noon ET.

  • Money line (ML): Giants -130 (bet $130 to win $100) | Patriots +105 (bet $100 to win $105)
  • Against the spread (ATS): Giants -2.5 (-108) | Patriots +2.5 (-112)
  • Over/Under (O/U): 33.5 (O: -115 | U: -105)

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Giants at Patriots picks and predictions

Prediction

Patriots 16, Giants 13

Money line

The PATRIOTS (+105) aren’t likely to run their 1st-team players out there much in this preseason opener. However, head coach Bill Belichick has plenty of depth to work with and New England has taken the preseason games very serious in recent seasons. Look for New England to get it done on its home turf.

Against the spread

The PATRIOTS +2.5 (-112) will likely have plenty of success confusing backup QBs Tyrod Taylor and Davis Webb for the Giants. Not sure what Vegas was thinking here, favoring the G-Men on the road. Take advantage.

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Over/Under

The UNDER 33.5 (-105) is a strong play. Traditionally we see lower-scoring affairs in the preseason, especially in the early-week games. The starters will play minimally, if at all, and the defensive units are usually well ahead of the reserves on offense. Toss in the fact we could see some slippery conditions due to showers, and the Under looks really good.

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New England Patriots at Buffalo Bills odds, picks and prediction

Analyzing Saturday’s Super Wild Card Weekend New England Patriots at Buffalo Bills odds and lines, with expert NFL picks, predictions and best bets.

For the third time this season, the AFC East-champion Buffalo Bills (11-6) and New England Patriots (10-7) face off in a big AFC East matchup. This time, it happens during the Super Wild Card Weekend. The game is slated for 8:15 p.m. EST, Saturday at Highmark Stadium. We analyze the Patriots vs. Bills odds and lines, and make our best NFL picks, predictions and bets.

They split games this season; both played during December, so the squads are very familiar with each other. New England won 14-10 at Buffalo Dec. 6, while Buffalo took care of business with a 33-21 road victory Dec. 26, as the two went back-and-forth atop the AFC East.

The Patriots have won four of the last five in Buffalo — the one loss coming last season. Granted, New England has looked very different at quarterback the past two seasons.

In its early December win, Patriots QB Mac Jones attempted just three passes, completing two for 19 yards in poor, windy weather conditions. Instead, they relied on RBs Damien Harris and Rhamondre Stevenson, who combined for 34 carries. Patriots head coach Bill Belichick is the ultimate game master; him relying heavily on the ground game and not on his rookie quarterback tonight would not be surprising.

Weather — at least very cold temps — will play a factor again. While wind is only predicted at 5 m.p.h., it’s expected to be just 4 degrees.

The Bills offense runs through QB Josh Allen, who has been in MVP consideration again this season. He has, however, struggled at home vs. New England:

  • 2021: 15/30, 145 pass yards, 1 TD, 0 INT, 1 FumL, 2 sacks
  • 2020: 11/18, 154 pass yards, 0 TD, 1 INT, 1 sack
  • 2019: 13/28, 153 pass yards, 0 TD, 3 INT, 4 sacks

Also see: All Wild Card odds and lines

Patriots at Bills odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 8:50 a.m. ET.

  • Money line: Patriots +190 (bet $100 to win $190) | Bills -240 (bet $240 to win $100)
  • Against the spread (ATS): Patriots +5.5 (-112) | Bills -5.5 (-108)
  • Over/Under (O/U): 43.5 (O: -117 | U: -103)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Patriots at Bills key injuries

Patriots

  • RB Damien Harris (hamstring) questionable
  • WR Jakobi Meyers (thigh) questionable
  • OT Isaiah Wynn (hip/ankle) OUT
  • DE Lawrence Guy (shoulder) questionable
  • LB Dont’a Hightower (knee) questionable
  • S Adrian Phillips (knee) questionable
  • PK Nick Folk (shoulder) questionable

Bills

  •  No injuries

Let’s Make This Interesting

Place your legal sports bets online in New Jersey and Colorado with Tipico Sportsbook, a trusted, global sports-betting leader. Iowa, get ready, Tipico is coming to your state soon! New customer offer: Deposit $10 or more, get $100 in instant bet credits! 21+, see Tipico.com for Terms and Conditions. Bet now!

Patriots at Bills odds, lines, predictions and picks

Prediction

Bills 19, Patriots 17

Money line

The Bills are the more talented team, and at -240, the juice on an outright win isn’t too pricey, but my confidence in them winning outright is waning on game day. Belichick will have the Patriots ready with a successful blueprint.

But which Buffalo team will show up?

It’s not that long ago (Nov. 21) Buffalo lost 41-15 at home to the Colts, or 9-6 to the Jaguars on the road. They beat the teams they should have (Panthers, Falcons and Jets) in December but went 1-2 versus playoff teams (New England twice, Tampa Bay), including that loss to this New England team.

I have no problem sprinkling a half-unit on the Patriots at +190 pulling an upset, but it isn’t the best bet to focus on, and I’d prefer to have wiggle room getting some points. PASS.

Against the spread

That said, I’m definitely digging the +5.5 line (-112) for the underdog Patriots, which feels about two points or more too wide in what should be a slow-paced, low-scoring, tight game in freezing temps. 

The Patriots are 10-7 ATS and 6-2 ATS on the road this season. Buffalo is 9-6-2 ATS, but 6-3 at home.

In the last three matchups in Buffalo, just 4.3 points separated the teams on average, with six points being the largest margin in a 2019 New England victory.

Hit the PATRIOTS +5.5 (-112) to cover for a full unit.

Over/Under

Only one of the past five meetings between these teams in Buffalo has gone over 40 points. On the season, Buffalo is 8-9 vs. the O/U, while New England is 9-8.

Both teams rushed for better than 2,150 yards — ranking in the top eight in the league — during the regular season, and both squads use multiple players to get the job done. That kills clock quickly. Look for long, sustained drives and ball-possession football to be the game script from both teams keeping the scoring opportunities lower and driving the score down.

Love the UNDER (43.5, -103) play here for at least a unit, maybe two.

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New England Patriots at Miami Dolphins odds, picks and prediction

Analyzing Sunday’s New England Patriots at Miami Dolphins odds and lines, with expert NFL picks, predictions and best bets.

The New England Patriots (10-6) head to South Beach Sunday for their Week 18 game with the Miami Dolphins (8-8) at Hard Rock Stadium. Kickoff is set for 4:25 p.m. ET. Below, we look at the Patriots vs. Dolphins odds and lines, and make our best NFL picks, predictions and bets.

New England clinched an AFC playoff berth and can still win the AFC East with a victory and if the New York Jets upset the Buffalo Bills.

The Patriots also have an outside shot at the AFC’s 1-seed but need to win Sunday and for the Bills, Kansas City Chiefs and Tennesee Titans to lose.

New England snapped a two-game losing skid in Week 17 by waxing the Jacksonville Jaguars 50-10 at home as a 17.5-point favorite. New England is 10-6 ATS and 8-8 O/U.

Miami was eliminated from playoff contention last week after getting blasted by the Titans 34-3 as a 3-point road underdog.

The Dolphins entered Week 17 on a seven-game winning streak after starting 1-7 but their magic ran out. The Dolphins are 8-7-1 ATS and 6-10 O/U.

Miami has won and covered versus New England in three of its past four meetings including on the road earlier this season 17-16 as a 3.5-point underdog.

Also seeBet Slippin’ Podcast: NFL Week 18 picks and predictions

Patriots at Dolphins odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:26 a.m. ET.

  • Money line: Patriots -300 (bet $300 to win $100) | Dolphins +230 (bet $100 to win $230)
  • Against the spread (ATS): Patriots -6.5 (-108) | Dolphins +6.5 (-112)
  • Over/Under (O/U): 39.5 (O: -117 | U: -103)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Patriots at Dolphins key injuries

Patriots

  • DB Kyle Dugger (hand) out
  • LB Dont’a Hightower (knee) out
  • David Andrews (shoulder) questionable
  • DT Christian Barmore (knee) questionable
  • Nick Folk (knee) questionable
  • RB Damien Harris (hamstring) questionable
  • WR Jakobi Meyers (thigh) questionable
  • DB Adrian Phillips (knee) questionable
  • OL Isaiah Wynn (hip) questionable

Dolphins

  • None.

Let’s Make This Interesting

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Patriots at Dolphins odds, lines, predictions and picks

Prediction

Dolphins 23, Patriots 17

Money line

SPRINKLE on the DOLPHINS (+230) because it’s a fat payout and I feel that good about Miami plus the points.

This line suggests that the Dolphins will mail it in Sunday and already be making their offseason plans. However, I reject that notion because Miami could’ve given up on its season after falling to 1-7.

Dolphins QB Tua Tagovailoa still has to prove he’s Miami’s franchise QB moving forward and there’s no better way to do that than to beat New England to end the season.

Patriots QB Mac Jones is still a rookie and has struggled in recent weeks. Jones has a 58.2% completion rate with a 5 TD/4 INT ratio and a 76.7 QB Rating in his last four games.

Dolphins head coach Brian Flores is a defensive mastermind from the Bill Belichick coaching tree and can install pressure and coverage schemes to confuse Jones.

Again, the plan is to SPRINKLE on the DOLPHINS (+230) and bet more on Miami plus the points.

Against the spread

Definitely BET the DOLPHINS +6.5 (-112) heavier than or instead of their money line.

Miami is 7-2 ATS in its past nine home games against New England and the home team is 15-4 ATS in the last 19 Patriots-Dolphins meetings.

The DOLPHINS +6.5 (-112) is my favorite wager in this contest.

Over/Under

PASS since my prediction aligns very closely to the projected total so I cannot call it either way.

The Under is too obvious since it’s cashed in four of the past five Patriots-Dolphins meetings. But, it’s hard not going Over a total set below 40 points.

Also seeNFL Week 18 odds and lines

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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Jacksonville Jaguars at New England Patriots odds, picks and prediction

Analyzing Sunday’s Jacksonville Jaguars New England Patriots odds and lines, with expert NFL picks, predictions and best bets.

On Sunday, the Jacksonville Jaguars (2-13) will travel to Gilette Stadium for a 1 p.m. ET kickoff with the New England Patriots (9-6). Below, we look at the Jaguars vs. Patriots odds and lines, and make our best NFL picks, predictions and bets.

The Patriots are coming into this game still having yet to clinch a playoff position. After snapping a seven-game winning streak against the Colts two weeks ago, the Patriots dropped a game last week against the Bills.

Led by rookie QB Mac Jones, the Patriots have leaned on a league-best defense and a dominant run game. That should be all they need against a QB Trevor Lawrence-led Jags.

The Jags have been among the worst teams in the league, heavily relying on the No. 1 overall pick. They’re coming off a discouraging loss in New York to the Jets.

Also seeBet Slippin’ Podcast: NFL Week 17 picks and predictions

Jaguars at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 10:30 a.m. ET.

  • Money line: Jaguars +700 (bet $100 to win $700) | Patriots -1200 (bet $1,200 to win $100)
  • Against the spread (ATS): Jaguars +16.5 (-112) | Patriots -16.5 (-108)
  • Over/Under (O/U): 41.5 (O: -110 | U: -110)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Jaguars at Patriots key injuries

Jaguars

  • TE James O’Shaughnessy (hip) out

Patriots

  • WR Nelson Agholor (concussion) out
  • RB Damien Harris (hamstring) questionable
  • DB Kyle Dugger (hamstring) questionable
  • LB Dont’a Hightower (knee) questionable

Let’s Make This Interesting

Place your legal sports bets online in New Jersey and Colorado with Tipico Sportsbook, a trusted, global sports-betting leader. Iowa, get ready, Tipico is coming to your state soon! New customer offer: Deposit $10 or more, get $100 in instant bet credits! 21+, see Tipico.com for Terms and Conditions. Bet now!

Jaguars at Patriots odds, lines, predictions and picks

Prediction

Patriots 27, Jaguars 13

Money line

PASS on the money line. I like New England here. So does everyone else. At -1200, it’s just not worth the value. The Pats are 8-1 vs. the Jags in the 2000s.

Against the spread

“LEAN” to the JAGUARS +16.5 (-112).

If there’s one thing that Jacksonville isn’t bad at, it’s stopping the run. The Jaguars rank 14th in opponents’ yards per rush attempt.

While the Jaguars rank 24th in opponents’ rushing yards per game, Jacksonville’s defensive style allows for opponents to run at them. If Harris misses this game, the Patriots run game will be even more hampered.

The Patriots rank 23rd in opponents’ rushing yards per game. If the Jags stick with the ground game and do what they do best defensively, they’ll have a shot to hang with New England.

The Jags haven’t cashed many ATS tickets this season, but at the same time, the Patriots are just 3-3 ATS as home favorites.

Over/Under

BET on the UNDER 41.5 (-110). The Jags offense just hasn’t been there this season. They’re tied with Chicago for the 26th-most yards per game.

The Jags have lived or died by No. 1 overall pick Lawrence. Scoring by far the fewest points per game at 14.5 PPG, the Jags have died by Lawrence more often. He has just a 58.7% completion rate.

The Patriots should heavily limit him, and with their run-heavy offense, they should run the clock down and move on to Week 18. The Pats have scored over 25 points in just two of the last seven weeks.

Also see: All Week 17 odds and lines

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and, soon, IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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Buffalo Bills at New England Patriots odds, picks and prediction

Analyzing Sunday’s Buffalo Bills at New England Patriots Week 16 odds and lines, with expert NFL picks, predictions and best bets.

The Buffalo Bills (8-6) and New England Patriots (9-5) meet in a crucial AFC East showdown Sunday at 1 p.m. ET (on CBS). Below, we look at the Bills vs. Patriots odds and lines, and make our best NFL picks, predictions and bets.

The Patriots lead the Bills by one game atop the division. New England took the first head-to-head meeting of the season 14-10 as a 3-point road underdog in Week 13.

In gusty winds, New England QB Mac Jones only attempted 3 passes, completing 2 for 19 yards, and the defense held the Bills to a season-low 230 offensive yards.

RB Damien Harris finished with 111 rushing yards, including a 64-yard touchdown, as the Pats outrushed the host Bills 222 to 99.

The Bills had a chance to take the lead late when they faced 1st-and-10 at the Patriots’ 14-yard line with 2:30 to go, but a 1-yard run followed by three incomplete passes sealed the New England victory.

Also see: All Week 16 odds and lines

Bills at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:54 a.m. ET.

  • Money line: Bills -105 (bet $105 to win $100) | Patriots -115 (bet $115 to win $100)
  • Against the spread (ATS): Bills +0.5 (-105) | Patriots -0.5 (-115)
  • Over/Under (O/U): 43.5 (O: -110 | U: -110)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Bills at Patriots key injuries

Bills

  • None

Patriots

  • WR Nelson Agholor (concussion) out
  • WR Rhamondre Stevenson (illness) out
  • C David Andrews (shoulder) questionable
  • DT Christian Barmore (knee) questionable
  • LB Ja’Whaun Bentley (ribs, ankle) questionable
  • RB Brandon Bolden (knee) questionable
  • K Nick Folk (knee) questionable
  • RB Damien Harris (hamstring) questionable
  • WR N’Keal Harry (hip) questionable
  • DB Adrian Phillips (knee) questionable

Let’s Make This Interesting

Place your legal sports bets online in New Jersey and Colorado with Tipico Sportsbook, a trusted, global sports-betting leader. Iowa, get ready, Tipico is coming to your state soon! New customer offer: Deposit $10 or more, get $100 in instant bet credits! 21+, see Tipico.com for Terms and Conditions. Bet now!

Bills at Patriots odds, lines, predictions and picks

Prediction

Patriots 30, Bills 24

Money line

PASS and just focus on the spread as they’re the exact same price.

New England is 3-4 straight-up (SU) at home and 3-2 as a home favorite, while Buffalo is 4-3 SU on the road and 1-1 as a road underdog.

Plus, Buffalo QB Josh Allen is 2-4 in his career vs. the Pats.

Against the spread

NEW ENGLAND -0.5 (-115) is the STRONGEST PLAY – 1½ times your usual wager.

The Patriots had not only won seven in a row, they covered seven in a row until a 27-17 loss at the Indianapolis Colts last week in a Saturday matchup.

They are 4-3 ATS at home this season, including 3-0 ATS in their last three at Gillette Stadium. New England is also 5-0 in its last five as a favorite.

The Bills, who snapped a two-game skid with a 31-14 home victory vs. the Carolina Panthers in Week 15, are 2-3 SU/ATS in their last five games.

They have been inconsistent against the spread. They are 4-3 ATS on the road and 0-4 ATS in their last four games following a SU win.

Over/Under

OVER 43.5 (-110) is the way to go.

Don’t expect a game like the last Bills-Pats meeting when New England only threw the ball 3 times. That was in extremely windy conditions.

The O/U is 7-0 in Buffalo’s last seven games as an underdog, including 5-0 in its last five as a road dog.

Plus, the O/U is 4-0 in New England’s last four home games.

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and, soon, IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

JOHNNY’S RECORD W-L SP ROI
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2021 NFL 17-15 7-7 -2.009
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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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New England Patriots at Indianapolis Colts odds, picks and prediction

Analyzing Saturday’s New England Patriots at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

The New England Patriots (9-4) are on the road against the Indianapolis Colts (7-6) Saturday as both teams come off their bye week. Kickoff from Lucas Oil Stadium is set for 8:20 p.m. ET. Below, we look at the Patriots vs. Colts odds and lines, and make our best NFL picks, predictions and bets.

The Patriots might be the hottest team in football as winners of their last seven games. Last time out they were on the road at the Buffalo Bills in Week 13, and high winds and resulted in the Patriots only throwing three times for 19 yards while rushing for 222 yards. New England has allowed a total of 36 points across its last five games.

The Colts are also on a bit of a run as winners of four of their last five games. Their only loss in that stretch was a 38-31 home defeat to the Tampa Bay Buccaneers. Indianapolis’ most impressive win of the season was undoubtedly a 41-15 dismantling of the Bills in Week 11 when it rushed for 264 yards.

Patriots at Colts odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 9:44 a.m. ET.

  • Money line: Patriots +115 (bet $100 to win $115) | Colts -140 (bet $140 to win $100)
  • Against the spread (ATS): Patriots +2.5 (-103) | Colts -2.5 (-117)
  • Over/Under (O/U): 44.5 (O: -108 | U: -112)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Patriots at Colts key injuries

Patriots

  • RB Damien Harris (hamstring) out
  • RB Brandon Bolden (knee) questionable
  • C David Andrews (shoulder) questionable
  • LB Ja’Whaun Bentley (ribs) questionable
  • OL Trent Brown (calf, wrist) questionable
  • PK Nick Folk (knee) questionable
  • Adrian Phillips (knee) questionable

Colts

  • C Ryan Kelly (knee, illness, personal) questionable
  • DT Antwaun Woods (calf) out
  • DT Grover Stewart (illness) questionable

Let’s Make This Interesting

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Patriots at Colts odds, lines, predictions and picks

Prediction

Patriots 24, Colts 20

Money line

It’s honestly shocking that the Patriots are underdogs in this one. They’ve won seven straight and are allowing 7.2 points per game over their last five. The Colts are playing well too, but they’re heavily reliant on RB Jonathan Taylor.

Bill Belichick is known for taking away a team’s best playmaker and you can bet he and the Patriots are going to sell out to stop the Colts’ run game, forcing QB Carson Wentz to beat them through the air — which he’ll struggle to do.

Bet the PATRIOTS (+115) to win outright.

Against the spread

The Patriots are 15-6 and 11-9-1 against the spread (ATS) coming off a bye since 2000. The Colts are also coming off a bye, but games like this typically lean the Patriots way with Belichick having an extra week to study and prepare for an opponent.

The Patriots are also 7-0 ATS during their seven-game win streak, while the Colts are only 3-3 ATS in their last six games.

Take the PATRIOTS +2.5 (-103).

Over/Under

Even considering how well the Patriots defense has been playing, the total has still managed to go Over four times in their last seven games. That’s because outside of their win against the Bills in those blistery conditions, the Patriots have scored at least 24 points eight times since Week 5.

This is an offense that’s going to efficiently move the ball and avoid costly turnovers. The Colts play a similar style of offense, which is why I think the total will go UNDER 44.5 (-112).

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New England Patriots at Buffalo Bills odds, picks and prediction

Analyzing Monday Night Football’s New England Patriots at Buffalo Bills odds and lines, with expert NFL picks, predictions and best bets.

The New England Patriots (8-4) visit the Buffalo Bills (7-4) in a pivotal AFC East clash in the Week 13 Monday Night Football game. Kickoff is scheduled for 8:15 p.m. ET from Highmark Stadium. Below, we look at the Patriots vs. Bills odds and lines, and make our best NFL picks, predictions and bets.

The Patriots are the hottest team in football, having won their last six games after starting the season 2-4. Their most recent win came in a 36-13 blowout of the visiting Tennessee Titans in Week 12. What’s most impressive about their winning streak is that all but one of their victories have been by at least 18 points.

The Bills cruised to an easy 31-6 win over the New Orleans Saints Thanksgiving Day, bouncing back from an embarrassing 41-15 home loss to the Indianapolis Colts the week prior. Since their bye in Week 7, the Bills are just 3-2 with losses to the Colts and the Jacksonville Jaguars, and with wins over the Miami Dolphins, New York Jets and Saints.

Patriots at Bills odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 12:20 p.m. ET.

  • Money line: Patriots +122 (bet $100 to win $122) | Bills -150 (bet $150 to win $100)
  • Against the spread (ATS): Patriots +2.5 (+102) | Bills -2.5 (-125)
  • Over/Under (O/U): 40.5 (O: -117 | U: -103)

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Patriots at Bills key injuries

Patriots

  • C David Andrews (shoulder) questionable
  • DL Christian Barmore (knee) questionable
  • LB Ja’Whaun Bentley (ribs) questionable
  • OL Trent Brown (calf) questionable
  • K Nick Folk (knee) questionable

Bills

  • OL Cody Ford (bicep) questionable

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Patriots at Bills odds, lines, predictions and picks

Prediction

Patriots 20, Bills 17

Money line

The PATRIOTS (+122) are on an absolute tear and although some of their opponents were on the weaker side, they did beat the Los Angeles Chargers, Cleveland Browns and Titans during their winning streak.

The winning continues Monday night against the Bills, who have been wildly inconsistent, particularly on offense.

Pats head coach Bill Belichick will draw up a game plan to bottle up Bills QB Josh Allen, forcing him into a turnover or two.

BET PATRIOTS (+122) to win outright, having beaten the Bills in seven of their last 10 meetings.

Against the spread

New England covered the spread in all six games during its recent winning streak and is now 8-4 ATS this season. The Bills are surprisingly 6-4-1 ATS despite losing to the Jags and getting blown out by the Colts. They did have blowout wins over the Dolphins, Washington, Houston Texans and Kansas City Chiefs earlier in the season.

All of Buffalo’s wins have been by at least 15 points. So, when it wins, it does so comfortably.

I just don’t think this is a game the Bills win, and I love getting the points with the Patriots on the road. BET PATRIOTS +2.5 (+102).

Over/Under

These are two of the highest-scoring teams in football. The Patriots average 28.0 points per game (PPG), while the Bills average 29.6.

They’re also two of the best defenses as the Patriots rank first in least points allowed (15.8 PPG) and the Bills are second (16.5 PPG).

Given how many turnovers each defense forces and how turnover-prone the opposing quarterbacks are, this will be a lower-scoring game in Buffalo.

BET NDER 40.5 (-103).

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Tennessee Titans at New England Patriots odds, picks and prediction

Analyzing Sunday’s Tennessee Titans at New England Patriots odds and lines, with expert NFL picks, predictions and best bets.

The Tennessee Titans (8-3) attempt to maintain their status as the No. 1 seed in the AFC as they are on the road against the red-hot New England Patriots (7-4). Kickoff for this pivotal AFC game is at 1 p.m. ET at Gillette Stadium. Below, we look at the Titans vs. Patriots odds and lines, and make our best NFL picks, predictions and bets.

The Titans had a six-game winning streak snapped last weekend when they lost 22-13 to the Houston Texans. They held Houston to only 190 yards of offense but turned the ball over five times. QB Ryan Tannehill threw a career-high four interceptions.

The Patriots have won five in a row. They have allowed a total of 13 combined points in their last three games. Rookie QB Mac Jones has been solid. Jones has completed 70.2% of his passes for 2,540 yards, 14 touchdowns and eight interceptions.

Also see: All Week 12 odds and lines

Titans at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 1:36 p.m. ET.

  • Money line: Titans +250 (bet $100 to win $250) | Patriots -320 (bet $320 to win $100)
  • Against the spread (ATS): Titans +6.5 (-103) | Patriots -6.5 (-117)
  • Over/Under (O/U): 43.5 (O: -108 | U: -112)

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Titans at Patriots key injuries

Titans

  • RB Jeremy McNichols (concussion) out
  • WR A.J. Brown (chest) IR-out
  • G Nate Davis (concussion) out
  • LB Rashaan Evans (ankle) out
  • LB David Long (hamstring) out
  • CB Greg Mabin (ankle) out
  • DT Teair Tart (ankle) out
  • TE Geoff Swaim (concussion) questionable
  • LB Jayon Brown (quadriceps) questionable
  • CB Elijah Molden (groin) questionable

Patriots

  • RB Damien Harris (neck) questionable
  • RB Rhamondre Stevenson (knee) questionable
  • TE Hunter Henry (neck) questionable
  • TE Jonnu Smith (shoulder) questionable
  • OT Trent Brown (calf) questionable
  • DT Christian Barmore (knee) questionable
  • LB Dont’a Hightower (ankle) questionable
  • LB Ja’Whaun Bentley (knee) questionable
  • K Nick Folk (knee) questionable
  • P Jake Bailey (knee) questionable

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Titans at Patriots odds, lines, predictions and picks

Prediction

Patriots 20, Titans 17

Money line

The Titans have weathered a lot this season. They enter this week with a ton of injuries. However, the defense has stepped up over the last few weeks, allowing an average of 18.3 points in the last five games.

However, without both Brown and Julio Jones, who is on injured reserve, as well as being without Derrick Henry, who is also on IR, Tennessee will not be able to generate enough offense.

The Patriots, on the other hand, have been great defensively as well, having allowed a total of 13 points in three weeks.

Because of the line where it is, though, PASS on the money line.

Against the spread

The Titans failed to cover the spread in their last two games but are 7-4 ATS overall this season. They have not covered the spread in any of their three losses.

The Pats are also 7-4 ATS but they have covered the spread in their last five games. The Titans will keep this game close. Ultimately, the Pats will do too much but the Titans will cover.

Take the TITANS +6.5 (-103).

Over/Under

The Titans are allowing an average of 18.6 points per game over their last five games. The Patriots are allowing only 10 points per game over their last five.

That combined with the Titans’ best offensive players being out means a low-scoring game.

Take UNDER 43.5 (-112).

Also seeBet Slippin’ Podcast: NFL Week 12 picks and predictions

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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New England Patriots at Atlanta Falcons odds, picks and prediction

Analyzing Thursday’s New England Patriots at Atlanta Falcons odds and lines, with expert NFL picks, predictions and best bets.

The New England Patriots (6-4) visit the Atlanta Falcons (4-5) in Week 11 for Thursday Night Football at Mercedes-Benz Stadium in Atlanta. Kickoff is scheduled for 8:20 p.m. ET. Below, we look at the Patriots vs. Falcons odds and lines, and make our best NFL picks, predictions and bets.

The Patriots roughed up the Cleveland Browns 45-7 in Week 10, winning and covering for the fourth consecutive game. The Pats are averaging 37.5 PPG across the past four outings, while yielding 12.5 PPG. The Over is 5-1 in the past six for the Patriots.

The Falcons scored a season-low three points last weekend at the Dallas Cowboys, getting trucked 43-3. While Atlanta is 1-2 SU/ATS across the past three games, at least they’re 2-0 SU/ATS this season vs. AFC East teams with the Over hitting in each outing.

Also see: All Week 11 odds and lines

Patriots at Falcons odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Wednesday at 7:21 p.m. ET.

  • Money line: Patriots -290 (bet $290 to win $100) | Falcons +225 (bet $100 to win $225)
  • Against the spread (ATS): Patriots -6.5 (-110) | Falcons +6.5 (-110)
  • Over/Under (O/U): 47.5 (O: -105 | U: -115)

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Patriots at Falcons key injuries

Patriots

  • P Jake Bailey (knee) questionable
  • OL Trent Brown (calf) questionable
  • DB Kyle Dugger (ankle) questionable
  • K Nick Folk (knee) questionable
  • LB Dont’a Hightower (ankle) questionable
  • OL Shaq Mason (abdomen) questionable
  • CB Jalen Mills (forearm) questionable
  • TE Jonnu Smith (shoulder) questionable
  • LB Kyle Van Noy (groin) questionable
  • DE Deatrich Wise Jr. (illness) questionable

Falcons

  • RB Cordarrelle Patterson (ankle) questionable
  • S Jaylinn Hawkins (ankle) questionable
  • TE Hayden Hurst (ankle) out

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Patriots at Falcons odds, lines, predictions and picks

Prediction

Patriots 30, Falcons 16

Money line

Patriots (-290) will cost you nearly three times your return. That’s just too expensive. Last Thursday night’s upset by the Miami Dolphins of the favored Baltimore Ravens should serve as a cautionary tale.

AVOID.

Against the spread

The PATRIOTS -6.5 (-110) have been playing very good football lately, looking like the contender we’ve known for the better part of the past two decades. New England “should” be able to win this one by at least one touchdown, but that’s always risky business on the road, so go lightly.

Over/Under

The UNDER 47.5 (-115) is the play here. It’s all about the Under lately in Thursday night tilts, going 7-1 across the past eight games. The short week is tough, and scoring is at a premium with the quick turnaround. Take advantage, and ride the trend hard.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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Cleveland Browns at New England Patriots odds, picks and prediction

Analyzing Sunday’s Cleveland Browns at New England Patriots Week 10 odds and lines, with expert NFL picks, predictions and best bets.

The Cleveland Browns (5-4) travel to meet the New England Patriots (5-4) Sunday for a Week 10 matchup at Gillette Stadium in Foxboro, Mass. Kick-off is scheduled for 1 p.m. ET. Below, we look at the Browns vs. Patriots odds and lines, and make our best NFL picks, predictions and bets.

The Browns picked up a huge win at Cincinnati last week, winning 41-16. That’s the good news. The bad news is the Browns will be without RB Nick Chubb, as he is on the reserve/COVID list, so RB D’Ernest Johnson will get the start.

The Patriots also have issues in the backfield, as RB Damien Harris is out with a concussion. RB Rhamondre Stevenson is still in the protocol and has a chance.

If not, it will be RB Brandon Bolden tasked with the start.

Browns at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 11:15 p.m. ET.

  • Money line: Browns +110 (bet $100 to win $110) | Patriots -135 (bet $135 to win $100)
  • Against the spread (ATS): Browns +2.5 (-108) | Patriots -2.5 (-112)
  • Over/Under (O/U): 44.5 (O: -112 | U: -108)

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Browns at Patriots key injuries

Browns

  • RB Nick Chubb (reserve/COVID) out
  • LB Jeremiah Owusu-Koramoah (ankle) questionable
  • CB Greedy Williams (shoulder) questionable

Patriots

  • RB Damien Harris (concussion) out
  • LB Dont’a Hightower (ankle) questionable
  • TE Jonnu Smith (shoulder) questionable
  • RB Rhamondre Stevenson (concussion) questionable
  • LB Kyle Van Noy (groin) questionable

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Browns at Patriots odds, lines, predictions and picks

Prediction

Patriots 22, Browns 19

Money line

The PATRIOTS (-135) are a good play if you want to avoid the points. This isn’t terribly out of line or expensive. With so many uncertainties at key positions on both sides of the ball, this is the way to go.

Against the spread

The PATRIOTS -2.5 (-112) are worth playing lightly, although I’d prefer to just play them straight up. The Browns +2.5 (-108) are 11-29-2 ATS across the past 43 against winning teams, although they are 5-1 ATS in the past six as a road underdog.

New England has owned this series, at least against the number, going 6-2 ATS in the past eight meetings, including 4-1 ATS in the past five in Foxboro. But all of that success was with a guy named QB Tom Brady under center.

Over/Under

The UNDER 44.5 (-108) is worth a look, as both teams will have key personnel either sidelined or not at 100 percent.

My only concern is that with both teams missing key parts of the run game, perhaps there is more of an aerial attack. Passing is never good for the Over.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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