10 Best College Football Predictions Against The Spread: Week 12. Big Week, Big Games, Big Picks

There’s no messing around with the 10 best college football predictions against the spread. These are the biggest games in the biggest week so far.

What college football games appear to be the best bets and the best picks going into Week 12? The 10 best predictions against the spread are the biggest games in the biggest week so far. 


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Week 12 Fearless Predictions, Game Previews 
CFN Week 12 Experts Picks: College
CFN Week 11 Experts Picks: NFL 
Week 12 Schedule, Game Times, Game Previews
Game Previews ACC | Big Ten | Big 12 | Pac-12 | SEC
College Football Playoff Rankings Reaction

Contact/Follow @ColFootballNews & @PeteFiutak

Results So Far ATS: 69-53-1

No goofing around

No gimmicks – the Kansas train finally came to a crashing halt, and in spectacular fashion. However, that was an overall plus to save my bacon after an offseason lobbying effort to get everyone to go over on the KU season win total of 1 or 1.5.

No obscure Group of Five on Group of Five action – because, to be honest, I couldn’t find anything.

No, it’s time to gear up and get in shape for what’s coming with the monster Thanksgiving Week around the corner – I’ll do this Wednesday before the Thursday and Friday games and then another version Friday night – leading into the conference championships leading into the bowl games.

But first, a bonus pick because I can’t resist, and because I’m not messing with a streak after falling into last week’s calls of Utah State outright over San Jose State (48-17 Aggies) and Nevada covering the 3 against San Diego State (SDSU 23-21).

It’s arguably the biggest game of the weekend, and I’m not going with it because I’m compromised.

For nine months I picked Utah to beat Oregon outright, and now 1) I hate Utah giving away points, 2) the pick fits my narrative, and that’s not a good thing – forgive the nauseating pretentiousness; I just chugged a latte at 2 am – and 3) I was yelled at by Oregon people that it’s not going to be as obvious as Oregon loses to Utah, Oregon beats Oregon State, Oregon beats Utah for Pac-12 Championship and goes on to beat random-good Big Ten team in the Rose Bowl.

Whatever. Of course that’s what’s going to happen. Utah -3. (BTW, biggest badass game preview photo ever for that.)

10 biggest college football games, 10 biggest college football picks. Here we go, starting with …

Click on each game for the preview

10. Virginia at Pitt

LINE Pitt -14.5
ATS PICK Virginia

Forgive me for doing this for a second week in a row.

Last week I loved the over in Virginia-Notre Dame, but that was based on Cavalier QB Brennan Armstrong playing. As it turned out, he couldn’t go with his injured rib and the team was a disaster in the 28-3 Irish win that didn’t come within ten miles of the total.

I might change this on the fly if news comes out about Armstrong one way or another, but at the moment the line is based on him not playing.

If he plays – and I’m guessing he tries everything to get out there with the Coastal Division still up for grabs – the line might plummet fast and the 14.5 should be a gift. However, that doesn’t quite jibe with the point total of 66.5.

If he’s not playing, UNDER if you can still get the 66.5. If he is playing, stay away from the total.

CFN Week 12 Experts Picks: College

9. SMU at Cincinnati

LINE Cincinnati -11
ATS PICK Cincinnati

I know this goes completely against my unwavering belief that Cincinnati not obliterating everyone with this schedule of meh is a disqualifier for the College Football Playoff, but I don’t believe in SMU at all.

No, Cincinnati hasn’t been as good as it should’ve been against awful teams, but yeah, Navy is quirky, and yeah, Tulsa is tough – and loses after bringing a decent fight – and the team did pull away from Tulane and USF.

SMU has been good enough over the last few years to get to the big stage, and then lose. Last year it was the 42-13 loss to Cincinnati. In 2019 it was the 54-48 loss to Memphis, and in 2018 – granted, that team was just okay – it was a 48-20 loss to UCF.

Cincinnati QB Desmond Ridder is playing better lately than he’s getting credit for, the lack of a consistent running game shouldn’t matter in this, and …

If this 2021 Bearcat ride ends, I think it happens either at East Carolina next week or against Houston in the AAC Championship.

CFN Week 11 Experts Picks: NFL

8. Oklahoma State at Texas Tech

LINE Oklahoma State -10.5
ATS PICK Oklahoma State

Interim head man Sonny Cumbie is coaching up this Texas Tech team through a tough situation. It fought well in a loss to Kansas State, got picked apart by Oklahoma, and then pulled off a Big 12 game-changer with a win over Iowa State. However …

Oklahoma State is fabulous.

This defense is incredible – it has yet to allow more than 24 points and gave up just 23 total in the last three games – the offense is finding its stride, and for all of his Mike Gundyness, Mike Gundy is really, really good at this and has his team peaking at the right time.

Texas Tech freshman QB Donovan Smith looks like a superstar to build around after ripping up Iowa State. However, Iowa State doesn’t get into the backfield like Oklahoma State does.

Donovan, meet the No. 1 pass rush and No. 3 defense in college football.

NEXT: College Football Pick Against The Spread No. 7: Nebraska at Wisconsin

Big Ten Predictions, Schedule, Game Previews, Lines, TV: Week 12

Big Ten Schedule, Game Previews, Predictions for Week 12: Michigan State at Ohio State, Purdue vs Northwestern, Rutgers at Penn State, Illinois at Iowa, Michigan at Maryland, Nebraska at Wisconsin, Minnesota at Indiana

Big Ten college football predictions, schedule, game previews, lines, how to watch, and TV listings for Week 11 of the season.


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Click on each game for game preview & prediction

Big Ten Results So Far
SU: 68-24, ATS: 62-30, Point Total: 56-35-1

Week 12 College Football Schedule, Predictions, Game Previews

Saturday, November 20

Michigan State at Ohio State

12:00, ABC
Line: Ohio State -19, o/u: 67

Purdue vs Northwestern (in Wrigley Field)

12:00, BTN
Line: Purdue -11, o/u: 47.5

Rutgers at Penn State

12:00, BTN
Line: Penn State -17.5, o/u: 47

Illinois at Iowa

2:00, FS1
Line: Iowa -12, o/u: 38.5

Michigan at Maryland

3:30, BTN
Line: Michigan -15, o/u: 56.5

Nebraska at Wisconsin

3:30, ABC
Line: Wisconsin -9.5, o/u: 42

Minnesota at Indiana

3:30, BTN
Line: Minnesota -7, o/u: 43.5

CFN Week 12 Expert Picks

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Fearless Predictions of Every Game
Bowl Projections | Rankings

College Football Expert Picks, Predictions: Week 12

College football expert picks and predictions for Week 12’s biggest games including Michigan State at Ohio State, Wake Forest at Clemson, Oregon at Utah, UCLA at USC, and Arkansas at Alabama

College football expert picks, predictions for Week 12, highlighted by Michigan State at Ohio State, Wake Forest at Clemson, Oregon at Utah, UCLA at USC, and Arkansas at Alabama


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* next to the pick means the team will win, but not cover.
Click on each game for the game preview and CFN Prediction

CFN Fearless Predictions & Game Previews

Week 12 College Football Expert Picks
WMU at EMU | NIU at Buffalo
CMU at Ball St | Louisville at Duke
Arizona at Wash St | SDSU at UNLV
Michigan St at Ohio St | Iowa St at OU
Wake Forest at Clemson | Illinois at Iowa
Ga Tech at Notre Dame | Arkansas at Bama
SMU at Cincinnati | Michigan at Maryland
Nebraska at Wisconsin | Florida at Missouri
UCLA at USC | Baylor at Kansas State
Auburn at South Carolina | Oregon at Utah
Virginia at Miami | Oklahoma St at Tex Tech
Arizona St at Oregon St | Col St at Hawaii
Results So Far | Week 12 Schedule  

Western Michigan at Eastern Michigan

7:30, ESPN2
Line: Western Michigan -5.5, o/u: 68

Patrick Conn, LSUTigersWire.com WMU
Adam Dubbin, GatorsWire.com WMU
Jeff Feyerer, CFN: WMU
Pete Fiutak, CFN: EMU
Dan Harralson, VolsWire.com: WMU*
Phil Harrison, BuckeyesWire.com: WMU
Jeremy Mauss, MWwire.com: EMU
Johnny Rosenstein, SportsBookWire.com: WMU*
Nick Shepkowski, FightingIrishWire.com: WMU
Joe Vitale, UGAWire.com: WMU
Clucko the Chicken, CFN: WMU
CONSENSUS PICK: WMU

NEXT: Northern Illinois at Buffalo Expert Picks, Predictions

10 Best Predictions Against The Spread: Week 13. It’s a B1G Week

What ten college football games appear to be the best bets and the best picks against the spread going into Week 13? Here you go. Enjoy.

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What ten college football games appear to be the best bets and the best picks against the spread going into Week 13? Here you go. Enjoy.


Week 13 Fearless Predictions, Game Previews 
ACC | Big Ten | Big 12 | Pac-12 | SEC
CFN Fearless Predictions & Game Previews
Week 13 Expert Picks & Predictions


Contact @PeteFiutak

10 Best ATS Picks So Far: 65-58


Click on each game for the game preview and fearless prediction.

And the ten games that appear to be a wee bit favorable are …

10. Samford at Auburn

LINE: Auburn -48.5
Live Stream: fuboTV (click to watch for free)
ATS PICK: Samford
Bet on this, BetMGM latest line

For those of you new to the program, here’s the tried-and-true, blind-faith belief system that’s worked really, really well this year.

If the world wants to give a team 40 points or more, you take them, you say “thank you,” and you move on.

There are a whole slew of things that have to happen to win by more than 40 points – it’s actually hard to do.

Sometimes a team shows mercy – like Ohio State did against Rutgers last week – and sometimes a team isn’t good enough to win by a bazillion, like Northwestern not covering against UMass.

However, there are a few things to take into account when it comes to the FBS vs. FCS matchups late in the season. 1) Is it the final home game for the FBSer? If it is, the starters will likely stay in a bit longer. Alabama is coming to Auburn next week. 2) Does the team need a week off to rest everyone?

You ready to play the deep cut on this?

The last two times Auburn played a wipeout paycheck game at home before going to Alabama, it won it brutal blowouts – by 53 over Liberty last year, and 55-0 against Alabama A&M in 2016. However …

The last few times it was the game BEFORE Senior Day – like it is this year? 42-14 over ULM in 2017, 56-34 over Idaho in 2015, 35-16 over Samford in 2011, 62-24 over UT Chattanooga in 2010, and 37-20 over UT Martin in 2008.

The gods are handing you 48.5 points AND a wacky trend/streak?

In this case, Samford actually has a fun enough offense that it can luck its way into a touchdown or two against the backups.

And from the Department of Oh Screw It, We’ve Come This Far With The Theme …

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9. Arkansas at LSU

LINE: LSU -43.5
Live Stream: fuboTV (click to watch for free)
ATS PICK: Arkansas
Bet on this, BetMGM latest line

Take everything that was just said about the FBS vs. FCS thing, and apply it to this.

The Arkansas Razorbacks will get up Saturday morning up 43.5-0.

LSU can win the SEC West with a victory, but it has bigger fish to fry next week against Texas A&M and the week after against Georgia in – most likely – the SEC Championship.

It’s not Senior Day – that’s next week – so this is just about coming up with an instant wipeout and then sitting everyone possible. Also, as dominant as LSU has been, it hasn’t won a game by more than 43 against an FBS team since the 55-3 win over Georgia Southern in the opener.

One more thing. After what happened last week to Tua Tagovailoa, but watch out for some teams to be a bit spooked about how long the superstar starting quarterback keeps playing in a blowout.

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8. Pitt at Virginia Tech

LINE: Virginia Tech -3.5
Live Stream: fuboTV (click to watch for free)
ATS PICK: Virginia Tech
Bet on this, BetMGM latest line

Stick with the hot hand. It’s the last home game of the year for a Virginia Tech team that’s in the thick of the ACC Coastal hunt. Pitt is, too, but the Hokies have rolled in their last two games, played Notre Dame well, and has won five of their last six games. Pitt is hot, too – winning six of its last seven – but the Hokies are sharper. You’re only giving away an extra half point taking the home team.

7. Nevada at Fresno State

LINE: Fresno State -14
Live Stream: fuboTV (click to watch for free)
ATS PICK: Nevada
Bet on this, BetMGM latest line

This isn’t the Fresno State of the last two years. The defense isn’t nearly as nasty, it  lost three of its last four, and the only win so far by more than 14 is over UNLV. The Bulldogs just played San Diego State – and lost – while Nevada has had two weeks off since winning on the road in San Diego. The Wolf Pack were blown away by Utah State and Wyoming on the road by a total score of 67-13 in their previous two road games, but the Bulldogs just aren’t that potent.

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6. Nebraska at Maryland

LINE: Nebraska -4.5
Live Stream: fuboTV (click to watch for free)
ATS PICK: Nebraska
Bet on this, BetMGM latest line

Nebraska has last four straight and five of its last six. It can’t seem to do much of anything right, and that includes only scoring 13 in a win over a miserable Northwestern team. However, the offense started to click last week against Wisconsin, Adrian Martinez played well, and the team wasn’t that bad in a 37-21 loss.

Maryland is rested after two weeks off, and it’s the home finale, but it hasn’t come closer than six of anyone but Rutgers since losing to Temple 20-17 back in mid-September. Basically, Nebraska is bad, but Maryland is a whole lot worse.

NEXT: The Top Five Picks of the Week Against the Spread

Big Ten Predictions, Schedule, Game Previews, Lines, TV: Week 13

Check out all the fearless predictions, game previews, lines and TV listings for Week 13 of the Big Ten season.

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Check out all the fearless predictions, game previews, lines and TV listings for Week 13 of the Big Ten season.


Results So Far: SU 75-15, ATS 42-43-1, o/u: 52-31-2

Click on each game for game preview & prediction

Penn State at Ohio State

12:00 FOX | Get Tickets
Live Stream: fuboTV (click to watch for free)
BetMGM Line: Ohio State -18.5, o/u: 57.5
Bet on this with BetMGM 

Minnesota at Northwestern

12:00 ABC | Get Tickets
Live Stream: fuboTV (click to watch for free)
BetMGM Line: Minnesota -13.5, o/u: 39.5
Bet on this with BetMGM 

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Illinois at Iowa

12:00 BTN | Get Tickets
Live Stream: fuboTV (click to watch for free)
BetMGM Line: Iowa -15.5, o/u: 46.5
Bet on this with BetMGM 

Michigan State at Rutgers

12:00 FS1 | Get Tickets
Live Stream: fuboTV (click to watch for free)
BetMGM Line: Michigan State -20.5, o/u: 43.5
Bet on this with BetMGM 

Michigan at Indiana

3:30 ESPN | Get Tickets
Live Stream: fuboTV (click to watch for free)
BetMGM Line: Michigan -9, o/u: 52.5
Bet on this with BetMGM 

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Nebraska at Maryland

3:30 BTN | Get Tickets
Live Stream: fuboTV (click to watch for free)
BetMGM Line: Nebraska -4, o/u: 62
Bet on this with BetMGM 

Purdue at Wisconsin

4:00 FOX | Get Tickets
Live Stream: fuboTV (click to watch for free)
BetMGM Line: Wisconsin -24.5, o/u: 48
Bet on this with BetMGM 

– CFN Fearless Predictions & Game Previews

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