Wofford at Duke odds, picks and predictions

Analyzing Saturday’s Wofford at Duke odds and lines, with college basketball expert picks, predictions and best bets.

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The Wofford Terriers (1-2) and the No. 6 Duke Blue Devils (2-1) meet at Cameron Indoor Stadium Saturday at noon ET (ACC Network). Let’s analyze BetMGM Sportsbook’s lines around the Wofford vs. Duke odds as we make our expert college basketball picks and predictions.

Wofford fell to 0-2 against Division I opponents, getting upset 71-68 by Presbyterian Wednesday as a 5.5-point road favorite with the Under (146) hitting. Wofford G Corey Tripp scored a team-high 15 points with a game-high 6 assists in the loss.

Duke suffered its first loss Tuesday, falling 77-72 as a 5.5-point favorite to No. 18 Kentucky in a neutral-site clash in Atlanta — the Under (159.5) cashed. Duke struggled from beyond the arc, shooting just 4-for-24 (16.7%) while Kentucky hit 10 of 25 (40.0%). F Cooper Flagg, Duke’s star freshman, finished with game-highs in points (26) and rebounds (11) in the defeat.

– RankingsUSA TODAY Sports Men’s Basketball Coaches Poll

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Wofford at Duke odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:54 a.m. ET.

  • Moneyline (ML): Wofford +2000 (bet $100 to win $2,000) | Duke -10000 (bet $10,000 to win $100)
  • Against the spread (ATS): Wofford +25.5 (-105) | Duke -25.5 (-115)
  • Over/Under (O/U): 147.5 (O: -115 | U: -105)

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Wofford at Duke picks and predictions

Prediction

Duke 87, Troy 60

Moneyline

PASS.

There’s no way anyone should consider betting Duke (-10000) at this price. That’s risking $100 to win a $1 — not a wise sports gambling strategy. However, when looking at the spread, things get more enticing.

Against the spread

BET DUKE -25.5 (-115).

This will be the third meeting between Duke and Wofford. The Blue Devils won the previous 2 matchups, both at home — in 2014 and 2019 — and by 29 points each.

Coming off their first loss of the season, Duke is primed to respond decisively. The Blue Devils’ 2 victories this season were by 42 and 36 points, covering spreads of 33.5 and 32, respectively. Flagg, coming off an impressive showing against Kentucky, is set to shine against Wofford’s subpar defense.

The Terriers, 0-2 ATS against Division I teams, also lost to Lipscomb by 9. Duke, 2-0 ATS all-time vs. Wofford, should easily cover this spread.

Over/Under

BET UNDER 147.5 (-105).

This matchup should finish similar to the previous 2 meetings where Duke averaged 85 points and Wofford 56. Wofford ranks 358th in possessions per game (63.1) and has yet to face a team of Duke’s caliber. The Terriers have gone Under in both of their D-I games this season, failing to score 70 points and likely staying under 60 here. Duke ranks 129th in possessions per game (74.4) and won’t push the tempo, favoring the UNDER (147.5) in this contest.

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Kentucky vs. Duke odds, picks and predictions

Analyzing Tuesday’s Kentucky vs. Duke odds and lines, with college basketball expert picks, predictions and best bets.

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The No. 18 Kentucky Wildcats (2-0) battle the No. 6 Duke Blue Devils (2-0) in the State Farm Champions Classic on Tuesday. Tip from State Farm Arena in Atlanta is scheduled for 9 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s college basketball odds around the Kentucky vs. Duke odds, and make our expert college basketball picks and predictions.

Kentucky beat the Bucknell Bison 100-72 on Saturday, pushing as a 28-point home favorite. G Koby Brea led all scorers with 20 points while C Amari Williams added a double-double (13 points, 14 rebounds).

Duke trounced the Army Black Knights 100-58 on Friday while covering as a 33.5-point home favorite. G Kon Knueppel scored a team-high 15 points with Duke getting double-doubles from G Cooper Flagg (13  points, 11 rebounds) and C Khaman Maluach (11 points, 14 rebounds).

– Rankings: USA TODAY Sports Men’s Basketball Coaches Poll

Stream select live college basketball games and full replays: Get ESPN+

Kentucky vs. Duke odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college basketball odds  Lines last updated at 9:45 a.m. ET.

  • Moneyline (ML): Kentucky +225 (bet $225 to win $100) | Duke -185 (bet $185 to win $100)
  • Against the spread (ATS): Kentucky +5.5 (-110) | Duke -5.5 (-110)
  • Over/Under (O/U): 160.5 (O: -110 | U: -110)

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Kentucky vs. Duke picks and predictions

Prediction

Duke 91, Kentucky 83

Moneyline

PASS.

There is minimal value on the Blue Devils (-185) to win on Tuesday.

Against the spread

LEAN DUKE -5.5 (-110).

Duke has scored 100 and 96 points in its 2 games and all of its starters have been getting involved. Knueppel and Flagg provide an edge to the Blue Devils that Kentucky will have a difficult time keeping up with. The size of the Blue Devils will be the difference-maker on Tuesday.

Over/Under

BET OVER 160.5 (-110).

Both teams have hit the Over in their 2 games, with Duke scoring 100 and 96 points while Kentucky has scored 103 and 100 points. Both teams flourish by speeding up the pace and knocking down transition shots, which is what will be the focus for both defenses heading into a difficult matchup. But both teams have displayed its ability to score.

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College sports coverage from USA TODAY Sports Media Group:
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Army at Duke odds, picks and predictions

Analyzing Friday’s Army at Duke odds and lines, with college basketball expert picks, predictions and best bets.

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The Army Black Knights (1-0) visit the Duke Blue Devils (1-0) on Friday. Tip from Cameron Indoor Stadium is scheduled for 6 p.m. ET (ACC Network). Let’s analyze BetMGM Sportsbook’s college basketball odds around the Army vs. Duke odds, and make our expert college basketball picks and predictions.

Army opened its season with a 67-59 win over the Albany Great Danes on Monday while covering as a 1.5-point home favorite. F Josh Scovens led all scorers with 22 points as only 3 Army players scored in double figures.

Duke opened its season on Monday with a 96-62 win over the Maine Black Bears while covering as a 32-point home favorite. G Kon Knueppel led 6 players scoring in double-figures with a game-high 22 points.

Duke is No. 5 in the USA TODAY Sports Men’s Basketball Coaches Poll.

Stream select live college basketball games and full replays: Get ESPN+

Army at Duke odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college basketball odds  Lines last updated at 11:01 a.m. ET,

  • Moneyline (ML): Off the board
  • Against the spread (ATS): Army +33.5 (-110) | Duke -33.5 (-110)
  • Over/Under (O/U): 142.5 (O: -110 | U: -110)

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Army at Duke picks and predictions

Prediction

Duke 89, Army 53

Moneyline

PASS.

Duke is such a heavy favorite on Friday that the moneyline is off the board. And ignore one if it appears.

Against the spread

LEAN DUKE -33.5 (-110).

While Duke is such a heavy favorite, it displayed its ability in its season opener with a 34-point cover win over Maine that involved multiple players getting involved on both ends of the court. Army had just 3 players in double-digits and struggled against Albany, a far lesser opponent than Duke will prove to be.

Over/Under

BET UNDER 142.5 (-110).

Army went way Under 142.5 in its first game, scoring 67 and limiting Albany to 59 at home. It will not have the same success defensively on Friday and it will struggle to keep up offensively, which will be the reason the Under hits. Duke held Maine to just 62 points in its opener.

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Maine at Duke odds, picks and predictions

Analyzing Monday’s Maine at Duke odds and lines, with college basketball expert picks, predictions and best bets.

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The Maine Black Bears and the 5th-ranked Duke Blue Devils meet at Cameron Indoor Stadium Monday in the regular season opener for both teams. Tip-off is scheduled for 7 p.m. ET (ACC Network) Let’s analyze FanDuel Sportsbook’s college basketball odds around the Maine vs. Duke odds, and make our expert college basketball picks and predictions.

The Black Bears are predicted to finish in the middle of the pack in the America East Conference (AEC). Maine’s top players are the 2 starters in the backcourt, Jaden Clayton and Kellen Tynes. Maine went 15-17 in the regular season in 2023-24, while going 18-12 against the spread (ATS), with the Under going 18-10-2.

There is a lot of anticipation over Duke’s season, as the Cooper Flagg era begins. Ironically, he is a native of the state of Maine. In fact, Flagg grew up just 36 miles from the campus of the University of Maine.

The Blue Devils are considered the favorites in the ACC, with holdovers Caleb Foster and Tyrese Proctor, as well as incoming prospects Flagg, Isaiah Evans, Kon Knueppel and Khaman Maluach.

This is just the 2nd-ever meeting between these teams on the hardwood. Duke pounded Maine 94-55 at Cameron on Dec. 3, 2016.

– Rankings: USA TODAY Sports Men’s Basketball Coaches Poll

Stream select live college basketball games and full replays: Get ESPN+

Maine at Duke odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college basketball odds. Lines last updated Monday at 6:58 a.m. ET.

  • Moneyline (ML): Maine +4000 (bet $100 to win $4,000) | Duke -50000 (bet $50,000 to win $100)
  • Against the spread (ATS): Maine +29.5 (-110) | Duke -29.5 (-110)
  • Over/Under (O/U): 134.5 (O: -115 | U: -105)

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Maine at Duke picks and predictions

Prediction

Duke 87, Maine 56

Moneyline

It shouldn’t need to be stated, but you can’t play Duke (-50000), even as part of a multi-leg parlay. Playing this heavy of a favorite means a 20-cent profit for every $100 risked. To make any kind of money whatsoever, you’d need to risk tons of money. It’s silly, but we’ll mention it anyway, but a wager of $10,000 would net a profit of $20.

AVOID.

Against the spread

DUKE -29.5 (-110) has a tremendous mix of talent, and this is easily coach Jon Scheyer’s best recruiting class since taking the reins from Coach K. Knueppel led the team with 18.0 points per game (PPG) in 2 exhibition games, while hitting 52.9% (9-of-17) from behind the 3-point line.

Duke has won 42 consecutive openers since 1981. This is the 17th consecutive season the Blue Devils are ranked in the preseason Top 10.

Over/Under

OVER 134.5 (-115) is a strong play in the opener, and easily the best on the board.

Duke dropped 92 points in a 92-54 win over Dartmouth in last season’s opener, and you can expect a similar offensive show from the Blue Devils. Maine won’t have to do much heavy lifting to get this one over the finish line.

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Duke at Miami odds, picks and predictions

Analyzing Saturday’s Duke at Miami odds and lines, with college football expert picks, predictions and best bets.

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The No. 5 Miami Hurricanes (8-0, 4-0 ACC) welcome the Duke Blue Devils (6-2, 2-2)  to Hard Rock Stadium Saturday. Kickoff is set for noon ET (ABC). Let’s analyze BetMGM Sportsbook’s college football odds around the Duke vs. Miami odds, and make our expert college football picks and predictions. Rankings are courtesy of US LBM Coaches Poll.

Miami clobbered the FSU Seminoles 36-14 in Week 9, but failed to cover as a 23-point favorite. Miami might have a perfect record, but it is just 1-3 against the spread (ATS) in its last 4 games, having won 3 of those games by just 1 score. The Hurricanes are led by QB Cam Ward, who has 24 TDs and 5 INTs in 8 games.

The Blue Devils won 5 in a row to start the season, but have stumbled over the last few weeks. They lost 24-14 to the Georgia Tech Yellow Jackets in Week 6 and then lost the SMU Mustangs 28-27 in overtime last Saturday, closing as an 11-point underdog. Duke has been a solid side for bettors though, having a 5-2-1 ATS record and going 4-0-1 ATS in its last 5 games.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Duke at Miami odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 7:01 a.m. ET.

  • Moneyline (ML): Duke +900 (bet $100 to win $900) | Miami -1600 (bet $1,600 to win $100)
  • Against the spread (ATS): Duke +20.5 (-110) | Miami -20.5 (-110)
  • Over/Under (O/U): 54.5 (O: -110 | U: -110)

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Duke at Miami picks and predictions

Prediction

Miami 38, Duke 24

Moneyline

PASS.

The Hurricanes should come out on top, especially playing at home. However, they aren’t worth a play as a far too expensive (-1600) favorite. The Blue Devils (+900) have struggled as of late and aren’t worth a play to pull off the upset.

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Against the spread

BET DUKE +20.5 (-110).

The Hurricanes just haven’t impressed over the last month, and it hasn’t been Ward’s fault. The offense is clicking, but their defense hasn’t held up against even subpar opponents. Miami has allowed 34 or more points in 3 of its last 4 games.

The Blue Devils offense has played well enough, scoring 20 or more points in 3 of their last 4 games, to keep this game relatively close. Duke has yet to allow more than 30 points in a game and has allowed over 24 just once. Expect the Blue Devils to play well enough to keep this within 21 points.

Back DUKE +20.5 (-110).

Over/Under

BET OVER 54.5 (-110).

The Hurricanes have been aggressive offensively throughout the season. They have scored 36 or more points in all 8 games, and they have topped 41  points 5 times.

Miami’s lacking defense over the last few weeks is key as well. It is 3-1 O/U in its last 4 games and is 6-1-1 O/U on the season. Duke went Over against SMU and is 3-3-1 O/U in its last 7.

Considering those trends, back OVER 54.5 (-110).

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SMU at Duke odds, picks and predictions

Analyzing Saturday’s SMU at Duke odds and lines, with college football expert picks, predictions and best bets.

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The SMU Mustangs (6-1, 3-0 ACC) meet the Duke Blue Devils (6-1, 2-1) in a Saturday night ACC battle in Durham. The contest at Wallace Wade Stadium will kick off at 8 p.m. ET (ACC Network). Let’s analyze BetMGM Sportsbook’s college football odds around SMU vs. Duke odds, and make our expert college football picks and predictions.

Southern Methodist is No. 22 in the US LBM Coaches Poll. The Mustangs roll into Durham on a 4-game win streak and have scored 45.5 points per game (PPG) over that stretch. SMU is playing its 3rd straight game on the road.

Duke has ridden close-game results to its fine midseason mark. The Blue Devils — whose 17.3 PPG allowed is the best average in the ACC — are 4-0 in games decided by 1 score.

US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

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SMU at Duke odds

Provided by BetMGM Sportsbook | FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 12:33 p.m. ET.

  • Moneyline: SMU -450 (bet $450 to win $100) | Duke +340 (bet $100 to win $340)
  • Against the spread (ATS): SMU -11.5 (-110) | Duke +11.5 (-110)
  • Over/Under (O/U): 48.5 (O: -115 | U: -105)

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SMU at Duke picks and predictions

Prediction

SMU 28, Duke 21

Moneyline

Too much juice here. PASS.

Against the spread

Look for Southern Methodist, playing its 3rd road game (with a West Coast trip in that mix) since Oct. 5, to be a fade-worthy candidate in trying to cover by this big number. The Mustangs are plus-7 in turnover margin; they are a plus-6 over their 4-game win streak. And they will be taking on a Duke squad which excels in causing havoc, especially in the front 7. The Devils are solid enough all the way around on defense and should find some turnover and/or field-position success in this night game at home.

On offense, Duke may well need some short fields. But if playing from behind, they are a) at least doing so against an SMU defense that yields a ton of explosive plays, and b) going against a Mustangs defense that has been awful in the red zone. In 21 trips inside the 20, SMU foes have tallied 16 TDs and a pair of field goals.

BACK THE BLUE DEVILS +11.5 (-110).

Over/Under

The Over is 3-1 across SMU’s last 4 games.

On a good-weather night in Durham and with the Blue Devils logging somewhat faster pace-of-play numbers of late, the OVER 48.5 (-115) is worth a sliver of a lean.

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College sports coverage from USA TODAY Sports Media Group:
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Florida State at Duke odds, picks and predictions

Analyzing Friday’s Florida State at Duke odds and lines, with college football expert picks, predictions and best bets.

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The Florida State Seminoles (1-5, 1-4 ACC) and Duke Blue Devils (5-1, 1-1) clash in a Friday showdown in Durham. Kickoff from Wallace Wade Stadium is scheduled for 7 p.m. ET (ESPN2). Let’s analyze BetMGM Sportsbook’s college football odds around the Florida State vs. Duke odds, and make our expert college football picks and predictions.

Florida State heads into this game off a bye week. The Seminoles last played Oct. 5, dropping a 29-13 home game against Clemson. FSU was doubled up in total yardage in that game 500 to 250, and the Seminole offense has yet to crank out even 300 yards in a single game.

Duke, also coming off a bye week, was tripped up 24-14 at Georgia Tech in its last game (Oct. 5). The Blue Devils were outperformed in 3rd and 4th-down plays in that contest, and the Yellow Jackets ran 80 plays to the Devils’ 51.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports 

Stream select live college football games and full replays: Get ESPN+

Florida State at Duke odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Thursday at 4 p.m. ET.

  • Moneyline: Florida State +130 (bet $100 to win $135) | Duke -155 (bet $155 to win $100)
  • Against the spread (ATS): Florida State +3 (-115) | Duke -3 (-105)
  • Over/Under (O/U): 42.5 (O: -110 | U: -110)

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Florida State at Duke picks and predictions

Prediction

Blue Devils 24, Seminoles 17

Moneyline

Duke is adept at creating havoc, and Florida State has often been pushed into passing downs by abysmal performance rates on early downs. On offense, the Blue Devils figure to be able to stay on schedule with a short passing game. In the red zone, DU has turned its last 9 trips into 7 TDs, and for the season the Devils are the better offense in punching in 6s.

DUKE (-155) has solid value.

Against the spread

Look for better return per the risk on the ML. PASS.

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Over/Under

The Under has cashed in 5 of FSU’s 6 games, and the Under is 4-2 across DU’s last 6 league games and 8-4 in the Blue Devils’ last dozen October games.

Both sides rank in the bottom half of FBS plays-per-game rankings; the Seminoles rank in the bottom 20%.

Florida State is adept in preventing 6s in opposing drives that reach the red zone. The Seminoles struggle in producing TDs on their own such drives. Down-and-distance-wise, both schools lean toward more clock-eating run plays than average.

Last year’s meeting cashed on an Over 49, but that game had 3 scoring drives under 50 yards in length, 2 defense/special teams scores and a garbage-time TD.

BACK THE UNDER 42.5 (-110) in this Friday nighter in Durham.

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College sports coverage from USA TODAY Sports Media Group:
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Duke at Georgia Tech odds, picks and predictions

Analyzing Saturday’s Duke at Georgia Tech odds and lines, with college football expert picks, predictions and best bets.

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The Duke Blue Devils (5-0, 1-0 ACC) visit the Georgia Tech Yellow Jackets (3-2, 1-2) Saturday. Kick from Bobby Dodd Stadium is scheduled for 8 p.m. ET (ACC Network). Let’s analyze BetMGM Sportsbook’s college football odds around the Duke vs. Georgia Tech odds, and make our expert college football picks and predictions.

Duke enters Saturday undefeated after narrowly defeating rival UNC 21-20 and covering as a 1.5-point home underdog. QB Maalik Murphy went 15-of-34 for 209 yards with a touchdown while his top receiver, WR Jordan Moore, hauled in 4 receptions for 80 yards. On the ground, RB Star Thomas carried the ball 30 times for 166 yards and a TD.

Georgia Tech fell 31-19 Sept. 21 against Louisville while failing to cover as a 9.5-point road underdog. QB Haynes King went 21-of-32 for 312 yards with WR Malik Rutherford grabbing 7 receptions for 113 yards. On the ground, King led the way and carried the ball 14 times for 58 yards and a TD.

US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

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Duke at Georgia Tech odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 11:30 a.m. ET.

  • Moneyline (ML): Duke +270 (bet $100 to win $270) | Georgia Tech -350 (bet $350 to win $100)
  • Against the spread (ATS): Duke +9.5 (-105) | Georgia Tech -9.5 (-115)
  • Over/Under (O/U): 53.5 (O: -105 | U: -115)

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Duke at Georgia Tech picks and predictions

Prediction

Georgia Tech 24, Duke 20

Moneyline

PASS.

While this could be a good opportunity to make money on Duke at +270, Georgia Tech is 10-1 under coach Brent Key following a loss while their offense is also one of only 3 teams in the nation to have not allowed a sack.

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Against the spread

BET DUKE +9.5 (-105).

Duke mounted a 21-0 run last week to come back and beat UNC and has not lost a game this season. It has covered the spread in 3 of its last 4 games including both games this season as an underdog. It has also scored 26 points or more in 4 of its 5 games. Georgia Tech has failed to cover the spread in 2 of its last 3 weeks and has allowed 31 points in each of those 2 games.

Over/Under

BET UNDER 53.5 (-115).

The Yellow Jackets have hit the Under in 4 of their 5 games this season while scoring 28 or fewer points in 3 of their 5 games. The Blue Devils have failed to hit the Over in 2 of their last 3 weeks and have allowed 21 or fewer points in each game this season.

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North Carolina at Duke odds, picks and predictions

Analyzing Saturday’s North Carolina at Duke odds and lines, with college football expert picks, predictions and best bets.

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The North Carolina Tar Heels (3-1) and the Duke Blue Devils (4-0) meet Saturday at Wallace Wade Stadium in Durham, N.C., for the ACC opener for both sides. Kickoff is scheduled for 4 p.m. ET (ESPN2). Let’s analyze BetMGM Sportsbook’s college football odds around the North Carolina vs. Duke odds, and make our expert college football picks and predictions.

North Carolina was embarrassed last week against visiting James Madison, as the Dukes dropped 53 on it — in the 1st half! JMU left Chapel Hill with $500K from the Tar Heels and a 70-50 victory. UNC was favored by 10.5 points as the Over (48) was nearly tripled up.

The Tar Heels offense has scored 38 or more points in 3 straight games, but UNC is 0-3 against the spread (ATS) in the past 3 outings and 0-3-1 ATS in 4 games to date. The Over and Under have alternated in each of the 4 contests.

Duke has won all 4 games to date, scoring 26 or more points in each outing. The Blue Devils have covered 2 of the past 3 outings, while the Over is 2-0-1 in the 3-game span.

The Tar Heels lead the all-time series 66-40-4, according to the UNC media guide, including wins in the past 5 meetings. That means the Victory Bell, awarded to the winner of this rivalry on the gridiron, has resided in Chapel Hill since Nov. 10, 2018. However, Duke has covered the previous 2 meetings, including a wild 47-45 2OT loss in Chapel Hill Nov. 11, 2023, as a 10-point underdog. The Over is 3-1 in the past 4 in the series.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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North Carolina at Duke odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 7:21 p.m. ET.

  • Moneyline (ML): North Carolina +120 (bet $100 to win $120) | Duke -145 (bet $145 to win $100)
  • Against the spread: North Carolina +2.5 (-105) | Duke -2.5 (-115)
  • Over/Under (O/U): 56 (O: -110 | U: -110)

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North Carolina at Duke picks and predictions

Prediction

North Carolina 32, Duke 29

Moneyline

NORTH CAROLINA (+120) is a solid play straight up at plus-money, as it takes the short ride up US 15-501 looking to bring the Victory Bell back down the road with another win over its rivals.

Duke (-145) is 4-0 straight up this season, but it struggled to shake off UConn at home 2 weeks ago and Northwestern took the Blue Devils to 2OT in Evanston before Duke won 26-20. The Blue Devils even struggled against FCS Elon for a majority of the opener before pulling away.

While the Blue Devils should find plenty of room against the leaky UNC defense, the Tar Heels look to have a much more powerful offense.

Against the spread

Playing North Carolina +2.5 (-105) and laying money, rather than playing it straight up at plus-money, makes little sense, unless you believe Duke -2.5 (-115) will win outright, but only by 1 or 2 points.

PASS.

Over/Under

OVER 56 (-110) is a strong play in this rivalry game. It has cashed in 3 of the previous 4 meetings.

Duke has hit high on the total at a 2-0-1 clip in the past 3 outings, and Duke has scored 26 or more points on offense in each of its 4 games.

For UNC, the offense has racked up 38 or more points in 3 consecutive games, and the defense was obviously a disaster last weekend.

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Duke at Northwestern odds, picks and predictions

Analyzing Friday’s Duke at Northwestern odds and lines, with college football expert picks, predictions and best bets.

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The Duke Blue Devils (1-0) and Northwestern Wildcats (1-0) clash Friday  in Evanston, Illinois. Kickoff at Martin Stadium will be at 9 p.m. ET (FS1). Below, we analyze BetMGM Sportsbook’s .. FanDuel Sportsbook’s lines around the Duke vs. Northwestern odds, and make our expert college football picks and predictions.

Duke scored in every quarter and did not allow any points until the final minute of its 26-3 season-opening win Aug. 30 vs. FCS Elon. QB Maalik Murphy helped make up for a lackluster Blue Devil ground game with a 26-of-40, 291-yard passing performance.

Northwestern opened its season — and its new temporary lakeside gridiron facility — with a dominant defensive performance in a 13-6 victory Aug. 31 over Miami (Ohio). The Wildcats held MU to just 267 total yards.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Duke at Northwestern odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:28 p.m. ET.

  • Moneyline: Duke +115 (bet $100 to win $115) | Northwestern -135 (bet $135 to win $100)
  • Against the spread (ATS): Duke +2.5 (-105) | Northwestern -2.5 (-115)
  • Over/Under (O/U): 37 (O: -110 | U: -110)

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Duke at Northwestern picks and predictions

Prediction

Duke 21, Northwestern 17

Moneyline

Duke and Northwestern met last Sept. 16 in Durham, N.C. The Blue Devils won that game 38-14 and since 2017 have won 5 straight against the Wildcats.

Duke is the lean here, but with a low-total scoring environment, look to leverage the Devils plus the points.

PASS.

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Against the spread

Look for the visitors to leverage a field-position edge and better big-play abilities. Expect NU to struggle in punching drives into the end zone.

QB Riley Leonard is gone, having transferred to Notre Dame. But last year’s Duke triumph was built more on the ground game. The Devils racked up 268 rushing yards in the 22-point victory.

BET DUKE +2.5 (-105).

Over/Under

The Over cashed in last year’s meeting and is 2-1 across the last 3 DU-NU games. The total has gone Over in 7 of Duke’s last 8 games on the road.

Peg both defenses as being mostly untested in August games against non-power-conference foes. In the exposed-to-Lake Michigan stadium, wind could be more of a factor than it was in the Wildcats-Redhawks game last week. But there is enough upside to the Duke offense and the two sides getting decent ground gains to warrant a play on the OVER 37 (-110).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTWFollow SportsbookWire on Twitter/X and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:
Alabama / Arkansas / Auburn / Clemson / Colorado / DukeFlorida / Florida StateGeorgia / Iowa / KentuckyLSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / UCLA / USC / WashingtonWisconsin / Recruiting / Transfer portal / College Football Playoffs / College Sports Wire / High School

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