Clemson Tigers betting odds line spread pick predictions best bets – Page 4

Clemson at Virginia odds, picks and predictions

Analyzing Tuesday’s Clemson at Virginia odds and lines, with college basketball expert picks, predictions and best bets.

The Clemson Tigers (21-8, 13-5 ACC) take on the No. 12 Virginia Cavaliers (21-6, 13-5) Tuesday at John Paul Jones Arena. Tip-off is scheduled for 7 p.m. ET. (ACC Network). Below, we analyze Tipico Sportsbook’s lines around the Clemson vs. Virginia odds, and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the USA TODAY Sports Coaches Poll.

The Tigers covered as 5.5-point road underdogs in their 96-71 victory over North Carolina State on Saturday. Clemson is tied for the 4th-best record in the ACC despite not being ranked.

The Cavaliers lost 71-63 to North Carolina on Saturday as they were unable to cover as 4.5-point road underdogs. Virginia has lost 2 games in a row but has still won 7 of its last 10 games.

This will be the first meeting between Clemson and Virginia this season. The Tigers and the Cavaliers have alternated covering the spread in the last 6 meetings.

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Clemson at Virginia odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:15 a.m. ET.

Moneyline (ML): Clemson +220 (bet $100 to win $220) | Virginia -270 (bet $270 to win $100)
Against the spread (ATS): Clemson +6.5 (-115) | Virginia -6.5 (-105)
Over/Under (O/U): 129.5 (O: -110 | U: -110)

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Clemson at Virginia picks and predictions

Prediction

Virginia 68, Clemson 65

Moneyline

AVOID.

Even with Virginia being 13-1 at home this season, taking the Cavaliers (-270) straight up isn’t advised at the current odds, especially with them losing 2 straight games.

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Against the spread

CLEMSON +6.5 (-115) is the pick in this ACC matchup. The Tigers are playing solid basketball recently and are 11-7 ATS against conference opponents this season.

The Cavaliers are 0-4 ATS in their last 4 games overall and the road team is 6-0 ATS in the last 6 meetings between these programs.

Over/Under

With Clemson being a formidable offensive squad, OVER 129.5 (-110) is the lean in this contest. The Tigers average 75.7 points per game (88th in the nation) and they convert 79.5% of their free throws (2nd).

Clemson is 6-1 to the Over in its last 7 road games and 6-0 in its last 6 games overall.

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Syracuse at Clemson odds, picks and predictions

Analyzing Wednesday’s Syracuse at Clemson odds and lines, with college basketball expert picks, predictions and best bets.

The Syracuse Orange (16-11, 9-7 ACC) face the Clemson Tigers (19-8, 11-5) Wednesday at Littlejohn Coliseum. Tip-off is at 7 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook’s lines around the Syracuse vs. Clemson odds, and make our expert college basketball picks, predictions and bets.

The Orange were blown out 77-55 by Duke on Saturday as 1-point underdogs at home. Syracuse is 5-5 in its last 10 games.

The Tigers lost 83-73 to Louisville on Saturday despite being 10.5-point road favorites. Clemson has lost 4 of its last 5 games, but still owns the 4th-best conference record.

This is the only regular-season meeting between the Orange and the Tigers. The home team has won 7 straight meetings.

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Syracuse at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:17 a.m. ET.

Moneyline (ML): Syracuse +145 (bet $100 to win $145) | Clemson -190 (bet $190 to win $100)
Against the spread (ATS): Syracuse +3.5 (-105) | Clemson -3.5 (-115)
Over/Under (O/U): 143.5 (O: -105 | U: -115)

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Syracuse at Clemson picks and predictions

Prediction

Clemson 77, Syracuse 71

Moneyline

AVOID.

Clemson should be able to secure the win at home, but taking the Tigers straight up at the current odds (-190) isn’t advised with how they’ve performed recently.

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Against the spread

CLEMSON -3.5 (-115) is the lean in this ACC showdown with the Tigers playing at home, where they are 13-1. Clemson convert 80% of their free throws, 2nd in the nation.

Clemson is 4-1 ATS in its last 5 home games and the home team is 6-1 ATS in the last 7 meetings between these programs.

Over/Under

OVER 143.5 (-105) seems like the ideal choice with Clemson likely being able to take advantage of Syracuse’s zone defense. The Tigers are making 36% of their 3-pointers (81st in the nation) and C PJ Hall should have success on the offensive glass.

The Orange are 6-1 to the Over in their last 7 road games and the Tigers have hit the Over in 4 straight games.

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Miami at Clemson odds, picks and predictions

Analyzing Saturday’s Miami at Clemson odds and lines, with college basketball expert picks, predictions and best bets.

The No. 21 Miami Hurricanes (17-5, 8-4 ACC) and No. 19 Clemson Tigers (18-5, 10-2) meet Saturday at Littlejohn Coliseum. Tip-off is scheduled for 3 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook’s lines around the Miami vs. Clemson game odds, and make our expert college basketball picks, predictions and bets.

The Hurricanes picked up a 92-83 win over Virginia Tech last time out at home Tuesday. Miami is 1-4 SU in the past 5 games on the road, including 4-straight losses outside of the state of Florida. However, The U is a solid 5-2 ATS across the past 7 games overall.

The Tigers were shocked at Boston College Tuesday night, snapping a 3-game winning streak. Clemson has failed to cover in the past 2 games, too, and it is trying to avoid its first 3-game, non-cover streak since opening the season 0-4 ATS in the first 4 games.

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Miami at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:40 a.m. ET.

Moneyline (ML): Miami +110 (bet $100 to win $110) | Clemson -130 (bet $130 to win $100)
Against the spread (ATS): Miami +1.5 (-105) | Clemson -1.5 (-115)
Over/Under (O/U): 146.5 (O: -110 | U: -110)

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Miami at Clemson picks and predictions

Prediction

Miami 70, Clemson 68

Moneyline

Miami (+110) is worth a sprinkle here as they have a good shot at the W here as short ‘dogs.

Take MIAMI +110.

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Against the spread

MIAMI +1.5 (-105) has had its issues on the road lately, winning only at lowly Florida State in the past 5 trips. However, the Canes are a very respectable 20-6 ATS in the past 26 road outings overall.

Clemson -1.5 (-115) has lost the past 2 meetings in this series, too, while going 0-4 ATS in the previous 4 matchups, and 1-6 ATS in the past 7 in the series overall. The ML is more lucrative, but the spread is there if you want a point of insurance.

Over/Under

UNDER 146.5 (-110) is the way to go here. The number has been steamed up from 141.5 over the last 12 hours.

The Under is 6-1-1 in the past 8 road games for Miami, while cashing at a 5-1 clip in the past 6 games after a straight-up win. The Under is 4-1 in the past 5 games at home for Clemson, too.

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Georgia Tech at Clemson odds, picks and predictions

Analyzing Tuesday’s Georgia Tech at Clemson odds and lines, with college basketball expert picks, predictions and best bets.

The Georgia Tech Yellow Jackets (8-11, 1-8 ACC) and No. 23 Clemson Tigers (16-4, 8-1) meet Tuesday. Tip-off from Littlejohn Coliseum is scheduled for 9 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook’s lines around the Georgia Tech vs. Clemson odds, and make our expert college basketball picks, predictions and bets.

The Yellow Jackets have dropped 5 in a row since the team’s last victory against the Miami Hurricanes at home on Jan. 4. Georgia Tech is just 3-8 ATS in the last 11 games.

Clemson eased by Virginia Tech 51-50 on Saturday as a 1-point favorite, bouncing back from a 87-77 loss at Wake Forest in the previous outing. Clemson is 7-2 ATS in the last 9 games. The Tigers crushed the Yellow Jackets 79-66 in Atlanta on Dec. 21, cashing as a 2-point favorite as the Over connected.

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Georgia Tech at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:27 a.m. ET.

Moneyline (ML): Georgia Teach +425 (bet $100 to win $425) | Clemson -650 (bet $650 to win $100)
Against the spread (ATS): Georgia Tech +10.5 (-105) | Clemson -10.5 (-115)
Over/Under (O/U): 138.5 (O: -115 | U: -105)

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Georgia Tech at Clemson picks and predictions

Prediction

Clemson 75, Georgia Tech 63

Moneyline

PASS.

Not worth pursuing anyway with Clemson so heavily favored.

Against the spread

CLEMSON -10.5 (-115)

The Tigers pounded Georgia Tech by 13 points on the road in the 1st meeting, and there’s no reason to believe the Yellow Jackets will be much better in the 2nd installment.

Georgia Tech is 1-4 ATS in the last 5 road games, while going 1-8 ATS in the previous 9 tries against teams with a winning overall mark.

Clemson is 7-2 ATS in the last 9 games overall, while cashing in 4 of the last 5 games at home.

Over/Under

UNDER 138.5 (-105) is the lean, but go with a half-unit at best.

The Under is connected in 6 of the last 7 road games for the Yellow Jackets, while going 6-1 in the last 7 road games against a team with a winning home mark.

The Under is also 5-2 for Clemson in the last 7 games against teams with a losing overall record, too.

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Clemson at Wake Forest odds, picks and predictions

Analyzing Tuesday’s Clemson at Wake Forest odds and lines, with college basketball expert picks, predictions and best bets.

The No. 19 Clemson Tigers (15-3, 7-0 ACC) and Wake Forest Demon Deacons (13-5, 5-2) meet Tueaday at Lawrence Joel Veterans Memorial Stadium in Winston-Salem, N.C. Tip-off is scheduled for 9 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook’s lines around the Clemson vs. Wake Forest odds, and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the USA TODAY Sports Coaches Poll.

The Tigers are the only unbeaten team in ACC play and are 1 1/2 games clear of the Miami Hurricanes. Clemson keeps proving it isn’t a fluke, covering a 1.5-oint line in a 72-64 win over Duke on Saturday. The Tigers are a solid 6-1 ATS in the last 7 games.

The Demon Deacons are also playing good basketball lately, winning 5 of the last 6 games. That includes a 22-point road win at Boston College on Saturday. The Over has cashed in 7 in a row for Wake.

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Clemson at Wake Forest odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:37 a.m. ET.

Moneyline (ML): Clemson +130 (bet $100 to win $130) | Wake Forest -160 (bet $160 to win $100)
Against the spread (ATS): Clemson +2.5 (-105) | Wake Forest -2.5 (-115)
Over/Under (O/U): 145.5 (O: -115 | U: -105)

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Clemson at Wake Forest picks and predictions

Prediction

Clemson 77, Wake Forest 75

Moneyline

CLEMSON (+130) keeps getting little respect from the books, and all it does is keep winning. Clemson is a perfect 7-0 inside the ACC, but it has still been an underdog in 3 of the last 4 games. It has won each of those outings straight up as an underdog.

Clemson roughed up Wake Forest 77-57 in the first meeting on Dec. 2, so what makes anybody think the Deacs are going to do a 180 here?

Against the spread

CLEMSON +2.5 (-105) is an impressive 6-1 ATS in the last 7 games overall, while going 5-2 ATS in the last 7 games on the road. It is also 18-7-2 ATS in the previous 27 against teams with a winning overall record.

Wake Forest -2.5 (-115) has covered 6 of the last 8 games at “The Joel,” including a rousing win over Duke. However, again, the Deacs lost by 20 in the 1st meeting, and it’s hard to back a team which was so very bad the 1st time around.

Over/Under

OVER 145.5 (-115) might be the best play on the board in this ACC tilt.

The Over is a respectable 8-4 in the last 12 games for the Tigers. And the Over is 7-0 in the last 7 games overall for the Deacs, while going 5-2 in the last 7 games at home. The Over is also 9-3 in the last 12 at home against teams with a winning road record.

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Duke at Clemson odds, picks and predictions

Analyzing Saturday’s Duke at Clemson odds and lines, with college basketball expert picks, predictions and best bets.

The No. 21 Duke Blue Devils (13-4, 4-2 ACC) battle the Clemson Tigers (14-3, 6-0) at Littlejohn Coliseum Saturday. Tip is set for 5 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook’s lines around the Duke vs. Clemson odds, and make our expert college basketball picks, predictions and bets.

The Blue Devils beat Pittsburgh 77-69 Wednesday, failing to cover as 9-point home favorites. Duke is 1-5 against the spread (ATS) over its last 6 games and just 7-10 against the spread (ATS) on the season and 1-2 straight up on the road. The Blue Devils’ strength is defense, allowing just 62.9 points per game (35th).

The Tigers beat Louisville 83-70 Wednesday, but they failed to cover as 15.5-point home favorites. The Tigers are 9-8 ATS on the season and a perfect 9-0 straight up at home. They are 5-1 ATS over their last 6. Clemson’s strength is offense, ranking 17h in the country in 3-point shooting percentage (38.9%).

Rankings courtesy of the USA TODAY Sports Coaches Poll.

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Duke at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11 a.m. ET.

Moneyline (ML): Duke -120 (bet $120 to win $100) | Clemson +100 (bet $100 to win $100)
Against the spread (ATS): Duke -1.5 (-110) | Clemson +1.5 (-110)
Over/Under (O/U): 140.5 (O: -105 | U: -115)

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Duke at Clemson picks and predictions

Prediction

Clemson 73, Duke 69

Moneyline

PASS.

Simply put, I think the Tigers win, but the spread should pose a better value. Clemson has losses this season of 2 points, 3 points and 18 points which suggests it can typically either win or keep games close.

With that in mind, I would snag the point instead of playing them outright.

Against the spread

BET CLEMSON +1.5 (-110).

The big difference between these two teams is how they have played in the respective site and how they’ve played conference opponents.

Duke is 1-5 ATS in conference games while Clemson is 5-1 ATS against ACC opponents. Duke is also 1-2 straight up (SU) on the road and 0-3 ATS on the road. Clemson is 4-5 ATS at home and 9-0 SU.

The Tigers are still being underrated by the market here, and I would back CLEMSON +1.5 (-110).

Over/Under

LEAN OVER 140.5 (-105).

Clemson ranks 60th in the nation in field goal percentage (47.2%) and 18th in 3-point percentage. It has gone Over in 2 straight games and in 6 of its last 8. Clemson is 6-3 O/U at home. While Duke is 7-10 O/U this season, it is 4-2 O/U in its last 6 games.

With the Blue Devils being one of the best free-throw shooting teams in the NCAA and this is expected to be a close game that could have late-game fouling, back the OVER 140.5 (-115).

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Orange Bowl: Clemson vs. Tennessee odds, picks and predictions

Analyzing Friday’s Clemson vs. Tennessee odds and lines, with college football expert picks, predictions and best bets.

The No. 11 Clemson Tigers (11-2) and the No. 6 Tennessee Volunteers (10-2) meet Friday in Miami for the Capital One Orange Bowl. Kickoff is scheduled for 8 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Clemson vs. Tennessee, and make our expert college football picks and predictions.

Rankings courtesy of AFCA Coaches Poll powered by USA TODAY Sports

Clemson ended its season with a 39-10 victory against North Carolina, finishing 8-0 in the ACC and 11-2 overall with both losses coming within the final 5 weeks of the season. The Tigers finished 7-6 against the spread (ATS) and had an Over/Under record of 7-6. Clemson’s offense put up an average of 404.6 yards per game, good for 55th in the nation, while their defense allowed only 20.1 PPG to rank 19th-best.

Tennessee capped off its season with a 56-0 victory against Vanderbilt to finish 2nd in the SEC East (6-2) behind Georgia. Tennessee looked unstoppable after a 62-59 victory against Alabama, but a knee injury to Heisman-hopeful QB Hendon Hooker derailed the season.

The Vols also fell victim to South Carolina in their 2nd-to-last game, getting blown out 63-38. The Volunteers finished the season 9-3 ATS with an Over/Under record of 7-5. Their offense ranked tops in the nation with 538.3 YPG while their defense ranked 44th giving up 23.5 PPG. Although they enter Friday as the underdog, the Vols can play with flare and keep things interesting.

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Clemson vs. Tennessee odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 12:26 p.m. ET.

Moneyline (ML): Clemson -230 (bet $230 to win $100) | Tennessee +180 (bet $100 to win $180)
Against the spread (ATS): Clemson -6 (-109) | Tennessee +6 (-111)
Over/Under (O/U): 63.5 (O: -108 | U: -112)

Clemson vs. Tennessee picks and predictions

Prediction

Clemson 38, Tennessee 28

Moneyline

PASS.

The odds do not present enough reward for the risk involved.

Against the spread

BET CLEMSON -6 (-109).

The Tennessee offense is only a shell of what it was under Hooker, especially with top WRs Jalin Hyatt and Cedric Tillman opting to head for the NFL Draft instead of playing.

Expect Clemson to be able to maintain a solid lead throughout. The Tigers are 4-0 ATS in their last 4 bowl games whereas the Volunteers are 0-4 ATS in their previous 4 neutral site games.

Over/Under

LEAN OVER 63.5 (-108).

Tennessee has the top-ranked offense in the nation, scoring an average of 47.3 PPG and Clemson’s ranked 25th at 34.7 PPG..

For Clemson, the Over is 4-0 in its last 4 games after allowing 20 or fewer points in its previous game and 4-0 in its last 4 following a straight-up win of 20 or more points. For what it’s worth, the Over is 4-0 in Tennessee’s last 4 Friday games.

Although some time has passed since their season finale, Clemson was starting to find its offensive identity, scoring at least 30 points in each of its final 4 games.

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ACC Championship: Clemson vs. North Carolina odds, picks and predictions

Analyzing Saturday’s Clemson vs. North Carolina ACC Championship Game odds and lines, with expert picks, predictions and best bets.

The No. 8 Clemson Tigers (10-2, 8-0 ACC) meet the No. 17 North Carolina Tar Heels (9-3, 6-2) Saturday at Bank of America Stadium in Charlotte. Kickoff is scheduled for 8 p.m. ET (ABC). Below, we analyze Tipico Sportsbook’s lines around the Clemson vs. North Carolina odds, and make our expert college football picks and predictions.

Ranking courtesy of AFCA Coaches Poll powered by USA TODAY sports

The Tigers are looking to rebound after a disappointing 31-30 loss at home to rival South Carolina in the regular-season finale, ending any chances of a shot at the College Football Playoffs. Clemson is just 2-2 SU in the last 4 games, while going 2-3 ATS in the last 5 games.

The Tar Heels were also bested by their rivals in the season finale, falling to NC State 30-27 in double overtime. UNC clinched the Coastal Division with a win Nov. 12 at Wake Forest, and proceeded to drop the final 2 games. The Under is 3-1 in the last 4 games for North Carolina.

These teams didn’t meet during the regular season and last played in 2019. The Tigers have won 4 straight in the series that started in 1897 and lead 38-15-1.

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Clemson vs. North Carolina odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 12:06 p.m. ET.

Moneyline (ML): Clemson -300 (bet $300 to win $100) | North Carolina +240 (bet $100 to win $240)
Against the spread: Clemson -8 (-109) | North Carolina +8 (-111)
Over/Under (O/U): 63.5 (O: -109 | U: -111)

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Clemson vs. North Carolina picks and predictions

Prediction

Clemson 34, North Carolina 30

Moneyline

Clemson (-300) is a little on the expensive side, costing you 3 times your potential return. That’s too much risk, and not enough reward, even if North Carolina (+240) has dropped 2 in a row and comes in with zero momentum.

PASS.

Against the spread

NORTH CAROLINA +8 (-111) is worth playing, even though the Tar Heels come in with very little momentum. QB Drake Maye has been among the most consistent quarterbacks in the ACC, and he and WR Josh Downs have had quite the rapport. Maye was even getting some Heisman attention prior to the 2-game skid.

Clemson -8 (-109) probably would have been the suggested play before the Tigers collapse against South Carolina in the finale. Now, there is doubt, especially as the Tigers will need to push the tempo to try to keep up with the high-octane Tar Heels attack. This will be a fun game to watch, and a game decided by 1 score.

Over/Under

OVER 63.5 (-109) is the lean, but go with a small-unit wager only.

UNC has rolled up 480.9 total yards per game to rank 11th in the country, while putting up 320.9 passing yards per game to check in 8th. The offense also has 37.1 PPG to rank 15th in the nation.

On the flip side, the Tar Heels D has made strides late in the season, but it is still very giving, allowing 30.3 PPG overall.

Clemson is good for 34.3 PPG to rank 27th in the nation, and this team allows just 20.9 PPG. But the UNC offense should be able to do much better than that.

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Wake Forest at Clemson odds, picks and predictions

Analyzing Friday’s Wake Forest at Clemson odds and lines, with college basketball expert picks, predictions and best bets.

The Wake Forest Demon Deacons (7-1, 0-0 ACC) and Clemson Tigers (6-2, 0-0) open their ACC play Friday at Littlejohn Coliseum. The opening tip will be at 7 p.m. ET (ACC Network Extra). Below, we analyze Tipico Sportsbook’s lines around the Wake Forest vs. Clemson odds, and make our expert college basketball picks, predictions and bets.

Wake Forest has won 3 straight games since falling 77-75 in overtime to Loyola Marymount Nov. 20. All 3 wins have been straight-up and against the number, including the Deacons’ last game when they beat the Wisconsin Badgers 78-75 as a 6-point road underdog Tuesday.

The Tigers also downed a Big Ten foe Tuesday when they covered as 2-point favorites with a 101-94 overtime win over Penn State. Clemson shot 50.8% from the floor and 52.4% from 3-point range in that win over the Nittany Lions. Since Nov. 15, the Tigers have shot 49.1% and 41%, respectively, in those categories.

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Wake Forest at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:25 a.m. ET.

Moneyline: Wake Forest +130 (bet $100 to win $130) | Clemson -160 (bet $160 to win $100)
Against the spread (ATS): Wake Forest +2.5 (-105) | Clemson -2.5 (-115)
Over/Under (O/U): 142.5 (O: -110 | U: -110)

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Wake Forest at Clemson picks and predictions

Prediction

Clemson 72, Wake Forest 68

Moneyline

The host Tigers (-160) are a lean at the current price but really only an actionable value at -150 or better. PASS.

Against the spread

The Tigers have gone 7-2 ATS in the last 9 Wake-Clemson meetings, including 2 straight ATS wins by double-digit margins.

Clemson has played a couple of foes at the Quadrant 1 and 2 levels and is 2-0 ATS in those games (vs. Iowa Nov. 25 and vs. PSU Tuesday). The ATS win over Iowa (in a 74-71 loss) was instructive, as it was a slow (Clemson)-vs.-fast (Iowa) match-up as is this game against Wake Forest which has a top-quartile tempo number.

Clemson has 4 high-impact players that are upperclassmen. Look for the home five to log an impressive performance in this ACC lid-lifter.

BACK THE TIGERS -2.5 (-115).

Over/Under

Peg this match-up for a bit of shooting regression, but a likely exchange of Clemson points of turnovers and Wake Forest points at the line counter that regression just enough to make this a total to LAY OFF.

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South Carolina at Clemson odds, picks and predictions

Analyzing Saturday’s South Carolina at Clemson odds and lines, with college football expert picks, predictions and best bets.

The South Carolina Gamecocks (7-4) meet the No. 8 Clemson Tigers (10-1) Saturday in a non-conference tilt at Memorial Stadium in Clemson, S.C. Kickoff is scheduled for noon ET (ABC). Below, we analyze Tipico Sportsbook’s lines around the South Carolina vs. Clemson odds, and make our expert college football picks and predictions.

Rankings courtesy of AFCA Coaches Poll powered by USA TODAY sports

The Gamecocks pulled off the giant upset over then-No. 5 Tennessee last weekend, winning 63-38 as a 23.5-point underdog. South Carolina would love to spoil the CFP hopes of another rival this weekend, but it is a much taller order on the road.

Clemson leads the all-time series 72-42-4, including victories in each of the past 7 meetings. In fact, while this is an intense rivalry, lately, it hasn’t even been close. The Tigers won 30-0 in Columbia last season, and it has taken each of the past 5 in the series by at least 21 points.

The Tigers are ranked No. 7 in the College Football Playoff rankings, and need a miracle to work their way into the top 4. It helped that South Carolina won last week against Tennessee, a team Clemson was competing with for a spot in the CFP, but it hurts that North Carolina lost to NC State Friday. A win by Clemson over UNC in the ACC Championship Game won’t look nearly as impressive now.

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South Carolina at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:20 a.m. ET.

Moneyline (ML): South Carolina +440 (bet $100 to win $440) | Clemson -600 (bet $600 to win $100)
Against the spread: South Carolina +14.5 (-112) | Clemson -14.5 (-108)
Over/Under (O/U): 52.5 (O: -111 | U: -109)

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South Carolina at Clemson picks and predictions

Prediction

Clemson 33, South Carolina 24

Moneyline

Clemson (-600) will cost 6 times the potential return, and that’s way too expensive in a rivalry game. Yes, the Tigers have had their way with the Gamecocks in recent years, but South Carolina is flying high and brimming with confidence after a giant win against Tennessee last weekend.

AVOID.

Against the spread

SOUTH CAROLINA +14.5 (-112) is a good play as long as this line stays at or above two touchdowns.

In previous years, Clemson -14.5 would seem like a gift as it has dusted South Carolina by an average of 31.8 points per game in the past 5 meetings. But USC has a lot of momentum after paddling Tennessee at Williams-Brice Stadium in Columbia last weekend.

The Gamecocks might not be able to get all the way over the hump to topple the Tigers, but they should be able to keep it within 2 TDs.

Over/Under

Play OVER 52.5 (-111), but don’t expect it to be easy.

Sure, South Carolina dropped 63 on Tennessee last weekend, but that’s an anomaly. The USC offense has been rather middling this season, posting 377.9 total yards per game to rank 78th in the nation, while running for just 129.5 yards per outing to check in 96th. The offense has scored 31.7 PPG to rank 42nd overall.

Clemson is also good, but not great, on offense, going for 34.7 PPG, while allowing just 20.0 PPG. The Tigers won’t get run over like the Vols last weekend, but we should still see a healthy score into the mid-50’s here. Just go lightly.

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