Louisiana Tech at Clemson odds, picks and predictions

Analyzing Saturday’s Louisiana Tech at Clemson odds and lines, with college football expert picks, predictions and best bets.

The Louisiana Tech Bulldogs (1-1) travel to Death Valley to take on the Clemson Tigers (2-0) Saturday. Kickoff is 8 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook‘s lines around the Louisiana Tech vs. Clemson odds, and make our expert college football picks and predictions.

The Bulldogs enter the game coming off a 52-17 win against FCS school Stephen F. Austin after an opening 52-24 loss against the Missouri Tigers. QB Parker McNeil led the way with 197 yards passing along with 3 TDs while RB Marquis Crosby added 196 yards rushing and 2 TDs. WRs Tre HarrisGriffin Hebert, and Smoke Harris each had a TD reception as the Bulldogs offense totaled 515 yards. They will hope for some explosive plays to get on the board early against a much stronger Clemson team.

The Tigers beat FCS school Furman last week 35-12 after a 41-10 win over Georgia Tech in the opener. QB DJ Uiagalelei had 21 completions for 231 yards, 1 TD and 1 INT while RB Will Shipley rushed for 68 yards with 2 TDs on 10 carries. In an atypical fashion, the Tigers struggled to bury their opponent. They had 2 turnovers and gave up more yards than they gained (384-376). They also had 6 penalties for 45 yards.

Clemson has beaten Louisiana Tech the 3 times they’ve played with the last meeting in 2006.

Clemson is No. 4 in the AFCA Coaches Poll powered by USA TODAY Sports.

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Louisiana Tech at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 8:29 a.m. ET.

  • Money line (ML): Louisiana Tech +2000 (bet $100 to win $,2000) | Clemson -10000 (bet $10,000 to win $100)
  • Against the spread (ATS): Louisiana Tech +33.5 (-112) | Clemson -33.5 (-108)
  • Over/Under (O/U): 53.5 (O: -112 | U: -108)

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Louisiana Tech at Clemson picks and predictions

Prediction

Clemson 45, Louisiana Tech 13

Money line

PASS. The -10000 odds will not return the rewards to make the risk worth the play.

Against the spread

LOUISIANA TECH +33.5 (-112).

The Bulldogs are a sound team coming off a game in which they were able to fine-tune their strengths. Although the Tigers will most likely separate themselves by halftime, LA Tech should be able to score enough points to cover. Furthermore, Clemson is just 1-8 ATS in September in their last 9 games.

Over/Under

UNDER 53.5 (-112).

This is not the offensive-dominant Clemson team that we have seen in previous years, rather the defense is the strong point of this team. For that reason, the under is a strong play. The under is 4-0 in the previous 4 Tigers games overall and 5-0-1 in their last 6 non-conference games.

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Furman at Clemson odds, picks and predictions

Analyzing Saturday’s Furman at Clemson odds and lines, with college football expert picks, predictions and best bets.

The Clemson Tigers (1-0) welcome the Furman Paladins (1-0) to Clemson Memorial Stadium Saturday. Kickoff is set for 3:30 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook‘s lines around the Furman at Clemson school odds, and make our expert college football picks and predictions.

Clemson is coming into this match after knocking off Georgia Tech 41-10 Labor Day night. The Tigers didn’t look like they were going to cover the 24-point spread for most of the battle but a 17-0 fourth quarter did the trick.

QB DJ Uiagalelei threw for 210 yards and a touchdown. He played well, but this was more about the Tigers’ top-notch defense, which allowed just 164 passing yards and 73 rushing yards.

As for Furman, it will be a heavy underdog despite a 52-0 win against North Greenville in its first game of the season. Starting QB Tyler Huff threw for 189 yards and 2 touchdowns. He completed 10 of 12 pass attempts before giving way to QB Jace Wilson (8-for-9, 77 passing yards) late in the first half.

The Paladins did have 4 players go for at least 49 rushing yards in their season opener. While unlikely, the road side may look to find some traction in their ground game.

Clemson is No. 4 in the AFCA Coaches Poll powered by USA TODAY Sports.

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Furman at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:56 a.m. ET.

  • Money line (ML): Off the board
  • Against the spread (ATS): Furman +44.5 (-115) | Clemson -44.5 (-105)
  • Over/Under (O/U): Off the board

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Furman at Clemson picks and predictions

Prediction

Clemson 59, Furman 10

Money line

PASS.

Even if there’s a money line posted before kickoff, don’t even consider it.

Against the spread

BET CLEMSON -44.5 (-105).

Clemson didn’t look great for most of last week’s game against Georgia Tech, but its defense said it all.

The biggest thing about these programs laced with high-level recruits is that they simply have a huge size difference. Clemson is going to win the middle and dominate the trenches.

That will ultimately help Clemson crush the rushing game and also limit what Furman does, especially since most of its offense came on the ground in its season-opening win.

In the Tigers’ 2 games against non-Power 5 teams last season, they beat South Carolina State by 46 (49-3) and Connecticut by 37 (44-7), the latter of which should be better than Furman.

Clemson should be able to come out on top easily and by a lot in this one.

Over/Under

The total is currently off the board at Tipico Sportsbook, but I would lean OVER on any O/U line UP TO 54.0 POINTS.

Furman did look great in its opener, but again the size in the trenches is what will matter.

With Clemson likely set to play backups for most of the second half if it leads big, expect Furman to generate some offense and be able to get on the board.

Clemson has held its opponent scoreless in just 2 games over the last 5 seasons. Furman should score, and given its Week 1 dominance, it may get on the board more than once.

Given the Clemson defensive strength, it’s just a lean, but I could see the Tigers scoring 54-plus points by themselves.

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Clemson vs. Georgia Tech odds, picks and predictions

Analyzing Monday’s Clemosn vs. Georgia Tech odds and lines, with college football expert picks, predictions and best bets.

The Clemson Tigers and Georgia Tech Yellow Jackets meet at Mercedes-Benz Stadium in Atlanta Monday. Kickoff is scheduled for 8 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook‘s lines around the Clemson vs. Georgia Tech odds, and make our expert college football picks and predictions.

The Tigers had a down year in 2021 by its recent standards. Clemson is hungry to get back to the ACC Championship Game, as well as to the College Football Playoffs. Clemson went 10-3 with a bowl win last season, and there aren’t many places where that’s considered mediocre.

The Yellow Jackets put up a strong fight against the Tigers in Death Valley last September, falling 14-8 while easily cashing as 27.5-point underdogs as the Under cashed. Georgia Tech didn’t win, but put up a much better effort after getting crushed 73-7 in Atlanta in October 2020.

Monday’s meeting is the 88th between the schools. Clemson has won 7 in a row and 9 of the last 10, but Georgia Tech leads the all-time series 51-34-2.

Clemson is ranked No. 4 in the AFCA Coaches Poll powered by USA TODAY Sports.

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Clemson vs. Georgia Tech odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 1:37 a.m. ET.

  • Money line (ML): Clemson -2000 (bet $2,000 to win $100) | Georgia Tech +900 (bet $100 to win $900)
  • Against the spread (ATS): Clemson -23.5 (-110) | Georgia Tech +23.5 (-110)
  • Over/Under (O/U): 50.5 (O: -117 | U: -103)

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Clemson vs. Georgia Tech picks and predictions

Prediction

Clemson 38, Georgia Tech 17

Money line

Clemson (-2000) will cost you 20 times your potential return, and that’s just too much risk for not enough reward. Over the course of a season, that’s a losing betting strategy picking heavy favorites.

PASS.

Against the spread

GEORGIA TECH +23.5 (-110) will be playing just a few miles from campus, so it could be argued that this is essentially a home game. But 1, that didn’t make much difference in 2020 when Clemson won by 66 at Bobby Dodd. And 2, Clemson’s campus is a short ride down I-85 to Atlanta, so there will be plenty of orange-clad fans at full throat.

The Yellow Jackets are the play here, though, as the Tigers offense struggled last season. Georgia Tech’s D held Clemson to just 14 points on its home field. While QB D.J. Uiagalelei should be much better in his 2nd full season, the Yellow Jackets are no longer the pushover they used to be. Look for Georgia Tech to at least hang around and keep it within 3 TDs.

Over/Under

OVER 50.5 (-117) is worth playing lightly.

We saw the Under cash in last season’s meeting at Death Valley, but the Over hit in Atlanta in 2020. The Over is also 5-2 in the last 7 ACC games for the Yellow Jackets, too. This won’t be a track meet, but it also won’t be a defensive slog like last year’s battle, either.

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Duke at Clemson odds, picks and prediction

Analyzing Thursday’s Duke at Clemson odds and lines, with college basketball expert picks, predictions and best bets.

The No. 6 Duke Blue Devils (19-4, 9-3 ACC) travel to Littlejohn Coliseum in Clemson, S.C., Thursday to take on the Clemson Tigers (12-11, 4-8). Tip-off is scheduled for 8 p.m. ET. Below, we look at the Duke vs. Clemson odds and lines, and make our expert college basketball picks, predictions and bets.

Duke had a five-game win streak snapped when they lost a 69-68 heartbreaker at home to the Virginia Cavaliers Tuesday as an 11-point favorite. The Blue Devils have recorded half of their losses at home.

Duke has the 17th-ranked offense with 80.2 points per game. Led by freshman phenom F Paulo Banchero, the Blue Devils are 13-8-2 ATS this season.

The Tigers are 13-9-1 ATS despite barely being over .500 on the season. They’ve lost three of their last four outings but did lose to Duke by 2 points in late January. The Tigers are led by 6-foot-10 F PJ Hall, who is averaging 15.3 points per game.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Duke at Clemson odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:44 a.m. ET.

  • Money line: Duke -290 (bet $290 to win $100) | Clemson +225 (bet $100 to win $225)
  • Against the spread (ATS): Duke -6.5 (-110) | Clemson +6.5 (-110)
  • Over/Under (O/U): 141.5 (O: -115 | U: -107)

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Duke at Clemson odds, lines, picks and predictions

Prediction

Duke 78, Clemson 66

Money line

PASS on the money line.

Duke is the superior team in terms of talent, but betting -290 for a team on the road is never wise. Similarly, the Tigers likely won’t have the weapons to pull off the upset, making their +225 line unplayable.

Against the spread

BET on DUKE -6.5 (-110).

Duke has oddly been better at covering on the road this season. The Blue Devils are 4-2 ATS on the road, covering in their last three games away from home. Duke is also a perfect 3-0 ATS following a win this season.

Clemson is just 5-6-1 ATS in conference teams, whereas Duke is 7-5 ATS.

The Blue Devils are 17th in field goal percentage and the Tigers 142nd in opponents’ field goal percentage and I’ll take the side that’s been hotter in this situation and shown more throughout the season.

Over/Under

Slight “LEAN” to the OVER 141.5 (-115).

The Over has been the preferred side in Clemson games. The Tigers are 13-10 O/U overall and 8-3 O/U at home. Clemson averages 72.8 points per game.

While this battle was a 71-69 showdown in the first meeting and the Under 145.5 hit, I’d prefer the higher end with the total dropping by 4 points in the rematch.

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Clemson at Duke odds, picks and prediction

Analyzing Tuesday’s Clemson at Duke odds and lines, with college basketball expert picks, predictions and best bets.

On Tuesday, the Clemson Tigers (11-8) will travel to Cameron Indoor Stadium to take on the No. 7 Duke Blue Devils (15-3). Tip-off is scheduled for 7 p.m. ET. Below, we look at the Clemson at Duke odds and lines, and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Duke is coming into this game as one of the better covering teams in the nation with a 10-6-2 against the spread (ATS) record. As a home favorite, they’re 7-4-2.

However, Duke is just 3-2 over their last 5 including a 2-point home loss to Miami (FL). They’ll be strong favorites as Clemson comes to town. However, Clemson has also proven to cover at a high rate, 10-8-1 ATS.

They’re entering this matchup coming off a 27-point home win over Pittsburgh, a much-needed victory as they were riding a three-game losing streak. Clemson is 0-0-1 against ranked opponents this season.

Clemson at Duke odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Odds for a full list. Lines last updated at 2:20 p.m. ET.

  • Money line: Clemson +520 (bet $100 to win $520) | Duke -800 (bet $800 to win $100)
  • Against the spread (ATS): Clemson +11.5 (-108) | Duke -11.5 (-112)
  • Over/Under (O/U): 145.5 (O: -110 | U: -110)

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Clemson at Duke odds, lines, picks and predictions

Prediction

Duke 78, Clemson 70

Money line

PASS on the money line.

Given Duke recently lost at home, betting 8.5 units on a win to return one just isn’t good value. Similarly, Clemson has lost 3 of their last 4, so I wouldn’t bank on upset either.

Against the spread

BET on CLEMSON +11.5 (-108).

When you look at how Duke has fared during conference play, it doesn’t show the same dominance. They’re 4-3 ATS but are covering by -1.7 points on average.

As for Clemson, they’re 3-5 ATS in ACC play. Clemson also lost by just 5 on the road to Miami (FL) whereas Miami went into Cameron Indoor and took down Duke.

Given that Clemson is forcing 11.9 turnovers per game in conference play (Duke averaged the conference’s 4th-most at 12.4 per game) and ranks second in opponents’ offensive rebounds, I’d give them a slight edge to cover. The backdoor cover is also a clear possibility with this size of margin.

Over/Under

“LEAN” to the OVER 145.5 (-110).

Clemson’s defense just isn’t quite there. They allow 73.2 points per game on the season. Meanwhile, the Blue Devils are topping 82 on the season, and keep that at 77.1 in conference play.

Duke is 9-9 O/U this season with Clemson at 11-8 O/U on the season. They’re respectively 3-4 O/U and 4-4 O/U in conference play.

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Cheez-It Bowl: Clemson vs. Iowa State odds, picks and prediction

Analyzing Wednesday’s Clemson Tigers vs. Iowa State Cyclones Cheez-It Bowl odds and lines, with college football expert picks, predictions and best bets.

The No. 22 Clemson Tigers (9-3) will take on the Iowa State Cyclones (7-5) in the Cheez-It Bowl in Orlando Wednesday. Kickoff from the Camping World Stadium is set for 5:45 p.m. ET. Below, we look at the Clemson vs. Iowa State odds and lines, and make our expert college football picks, predictions and bets.

Clemson came into this season with sky-high expectations, having been one of the best programs in college football over the last few seasons. It lost 10-3 to now-No. 2 Georgia in its season opener and lost to current-No. 18 NC State 27-21 in overtime three games later.

Clemson may have had a mediocre offense, but its defense is elite. It allowed the second-fewest points in the nation (15.0 points per game). The Tigers were just 4-8 against the spread (ATS) this season, while the Cyclones were marginally better at 5-7.

While the Cyclones do have a more dynamic offense, one that features both a quarterback with over 2,800 yards and running back with over 1,400 yards, their main strength is also in their defense, one that allows the 10th fewest yards per game.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Clemson vs. Iowa State odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:48 a.m. ET.

  • Money line: Clemson -140 (bet $140 to win $100) | Iowa State +115 (bet $100 to win $115)
  • Against the spread (ATS): Clemson -2.5 (-115) | Iowa State +2.5 (-107)
  • Over/Under (O/U): 44.5 (O: -110 | U: -110)

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Clemson vs. Iowa State odds, lines, picks and predictions

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Prediction

Clemson 23, Iowa State 17

Money line

PASS. I’ll take the Clemson spread for 25 more cents on the dollar. Given that value, I’d rather play the points and wouldn’t feel comfortable enough in the Tigers to put much on a -140 money line regardless.

Against the spread

“LEAN” to CLEMSON -2.5 (-115) as its defense should be able to put it on the Cyclones offense. The Cyclones average almost 170 yards per game. Freeing up their pass game by moving the chains on the ground has been a routine for Iowa State.

They’ll be battling a Clemson rush defense that ranks ninth in the country in opponents’ rushing yards. It is a legit group with several highly-touted recruits.

Also, Cyclones leading rusher RB Breece Hall will not be playing, so that takes their offense down a huge notch.

His absence will give a huge boost to the Tigers. It must be QB Brock Purdy who gives the Cyclones any chance, and I’d rather bet for the Tigers defense than against it in this situation.

Over/Under

BET UNDER 44.5 (-110) as the Cyclones will be down their leading rusher and the Clemson offense has been inconsistent at best all season. The Clemson offense ranks 103rd in passing nationally and 56th in rushing.

Bad news for Clemson is that Iowa State has a top-25 rush defense. It should be able to limit what Clemson does best. Given Hall’s absence and the Tigers’ elite defense, I’d bank on fewer points.

Per pregame.com, we’re seeing some reverse-line movement with the vast majority of the money on the Over, but this total moving from 45 down to 44.5. The sportsbooks like their positions, and you should, too.

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College sports coverage from USA TODAY Sports Media Group:

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Clemson at South Carolina odds, picks and prediction

Analyzing Saturday’s Clemson at South Carolina odds and lines, with college football expert picks, predictions and best bets.

The Clemson Tigers (8-3, 6-2 ACC) head to Columba, S.C., to take on the South Carolina Gamecocks (6-5, 3-5 SEC) Saturday. Kickoff for the 118th edition of this rivalry game is 7:30 p.m. ET. Below, we look at the Clemson at South Carolina odds and lines, and make our expert college football picks, predictions and bets.

Clemson has recovered from a disastrous start to its season—the Tigers were 4-3, 0-7 ATS through their first seven games—to reel off four straight wins, three of which have covered the spread. The offense has picked things up, averaging 38.0 points per game over the last four contests, while the defense (319.7 yards per game; 15th nationally) has been excellent all year.

Rankings according to the AFCA Coaches Poll powered by USA TODAY Sports.

South Carolina is also finishing strong under first-year head coach Shane Beamer. The Gamecocks are coming off a 21-17 win vs. Auburn and also beat Florida 40-17 Nov. 6. The offense has been hampered by injuries at quarterback as it’s averaging just 332.2 yards per game (111th nationally) and 26.5 points per game (104th).

Clemson at South Carolina odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 7:45 a.m. ET.

  • Money line: Clemson -500 (bet $500 to win $100) | South Carolina +330 (bet $100 to win $330)
  • Against the spread (ATS): Clemson -10.5 (-115) | South Carolina +10.5 (-107)
  • Over/Under (O/U): 43.5 (O: -108 | U: -112)

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Clemson at South Carolina odds, lines, picks and predictions

Prediction

Clemson 30, South Carolina 17

Money line

We can’t really make a case for South Carolina winning this game, and the payout is too low for Clemson, so PASS on the money line.

Against the spread

It’s hard to see how South Carolina is going to put up many points with a fourth-string quarterback going up against a defense that has allowed 16.8 points per game this year. Further, Clemson’s running game is starting to wake up and should make hay against South Carolina’s 93rd-ranked rushing defense (171.4 yards per game).

The Tigers are on a six-game winning streak over South Carolina, and only one of those games has been close. Look for CLEMSON -10.5 (-115) to roll.

Over/Under

This is a low number and the Over has hit in three of these teams’ last four games. Look for Clemson to do most of the heavy lifting with its improved offense, while the defense will allow just enough points to take this OVER 43.5 (-108).

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Wake Forest at Clemson odds, picks and prediction

Analyzing Saturday’s Wake Forest Demon Deacons at Clemson Tigers odds and lines, with college football expert picks, predictions and best bets.

The No. 12 Wake Forest Demon Deacons (9-1, 6-1 in ACC) face off with the Clemson Tigers (7-3, 5-2) in an ACC Atlantic game at Memorial Stadium with the kickoff scheduled for noon E.T. Below, we look at the Wake Forest vs. Clemson odds and lines, and make our expert college football picks, predictions and bets.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Wake Forest bounced back from its first loss of the season to beat the NC State Wolfpack 45-42 as 1-point road favorites in Week 11. The Demon Deacons are 5-5 ATS and 5-5 O/U with the 68th-toughest schedule, according to USA TODAY’s Jeff Sagarin.

Clemson won its third straight game by pummeling the UConn Huskies 44-7 but failed to cover as 41-point home favorites. This will be the first Clemson team to not make the College Football Playoff since 2014.

The Tigers are 2-8 ATS and 3-6-1 O/U with the 51st-ranked strength of schedule, according to Sagarin.

Clemson thrashed Wake Forest 37-13 as 34-point favorites last season but the Tigers obviously lost a lot of pieces including former QB Trevor Lawrence.

However, Demon Deacons QB Sam Hartman played in last year’s Clemson-Wake Forest game. Hartman completed 11-of-21 passes for 182 yards.

Wake Forest at Clemson odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 2 p.m. ET.

  • Money line: Wake Forest +160 (bet $100 to win $160) | Clemson -200 (bet $200 to win $100)
  • Against the spread (ATS): Wake Forest +4.5 (-112) | Clemson -4.5 (-108)
  • Over/Under (O/U): 56.5 (O: -115 | U: -107)

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Wake Forest at Clemson odds, lines, picks and predictions

Prediction

Clemson 30, Wake Forest 23

Money line

PASS because I “lean” to Clemson laying the points but wouldn’t play the Tigers outright at that price. It is funny though that a disastrous season at Clemson could still end in a nine-win year.

The bottom line for me is that I have faith even Clemson’s terrible offense can have success against Wake Forest’s Swiss cheese defense. Whereas I don’t expect any offense to have success vs. Clemson’s defense.

Don’t get me wrong, there are a couple of offenses this season that have done alright against the Tigers. But, Clemson’s defense still ranks seventh in the nation in predicted points added (PPA) and eighth in success rate.

Against the spread

“LEAN” to CLEMSON -4.5 (-108) because this is just a game Wake Forest is supposed to lose. The Demon Deacons could finish with an 11-win season, which seems insane considering Wake Forest’s defense ranks 103rd in PPA and 111th in success rate.

Also, there’s been a “line freeze” in the betting market. Circa Sports in Las Vegas opened this game with Clemson laying 5 points.

According to Pregame.com, nearly 80% of the action is on Wake Forest but this line has only moved a half-point. A profitable spot when betting college sports is fading ranked teams on the road in conference play.

GIMME a CLEMSON -4.5 (-108) at home and looking to spoil an overrated conference foe’s season that the public is betting against.

Over/Under

“LEAN” to the UNDER 56.5 (-107) because I think Clemson’s defense is going to show up in its final home game of the season.

Also, the oddsmakers have adjusted their totals for how prolific Wake Forest’s offense has been this year. Again, Wake Forest is 5-5 O/U and the Demon Deacons have scored a combined 33 points in four seasons vs. Clemson.

Sure, this Wake Forest offense is better than the previous four, but a vast majority of the public is betting the Over in this one as well. Again, let’s fade the market and HIT the UNDER 56.5 (-107) for a light wager.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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UConn at Clemson odds, picks and prediction

Analyzing Saturday’s UConn Huskies at Clemson Tigers odds and lines, with college football expert picks, predictions and best bets.

The UConn Huskies (1-8) visit Clemson Memorial Stadium to take on the Clemson Tigers (6-3) Saturday. Kickoff for the non-conference tilt is scheduled for noon ET. Below, we look at the UConn at Clemson odds and lines, and make our expert college football picks, predictions and bets.

The Tigers have had a relatively disappointing season after being projected to contend for a CFP spot. Clemson still has talent at all positions, but losses to Pitt, NC State and Georgia will continue to haunt it.

Clemson’s offensive line has been a problem all season long, but it should hold up against a pitiful UConn team. The Huskies have just one win and will have no business hanging around in this game.

They’ve beaten Yale but have since lost to Middle Tennessee by 31. They’ve lost games by 45 and 49 to currently unranked teams. It’s been a brutal season that may get even rougher Saturday.

UConn at Clemson odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 11:31 p.m. ET.

  • Money line: Off the board
  • Against the spread (ATS): UConn +40.5 (-105) | Clemson -40.5 (-120)
  • Over/Under (O/U): 51.5 (O: -107 | U: -115)

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UConn at Clemson odds, lines, picks and predictions

Prediction

Clemson 45, UConn 3

Money line

PASS, obviously. There aren’t any odds because it just wouldn’t make sense to allow any ultra-rich bettor to slap $100,000 on this one. The upset possibility just isn’t here.

Against the spread

BET CLEMSON -40.5 (-120) as the Tigers have been a solid team this season. Are they a top-10 team in the nation? No. But they have handled subpar teams.

They defeated SC State by 46. Aside from that, they really haven’t had any gimme games. This is one of them. Clemson is almost averaging 150 yards on the ground.

UConn allows almost 200 yards per game. Clemson should run all over the Huskies and should score with ease. UConn averages the 124th most points in the FBS at just over 16 per game.

This one should be all Tigers.

Over/Under

“LEAN” to UNDER 51.5 (-115) as Clemson’s passing game has been nonexistent.

While I think the Tigers defense should get the best of a UConn team that’s struggled to move the ball, betting the Under is about the incompetent Tigers pass game.

With superstar QB Trevor Lawrence off to the NFL, QB D.J. Uiagalelei took over, and Clemson has struggled heavily, ranking in the bottom third in the FBS in passing yards per game.

Given that and the strength in the run game, especially with that being a clock-killing strategy, expect the Under to hit.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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College sports coverage from USA TODAY Sports Media Group:

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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Clemson at Louisville odds, picks and prediction

Analyzing Saturday’s Clemson at Louisville odds and lines, with college football expert picks, predictions and best bets.

The Clemson Tigers (5-3, 4-2 ACC) pay a visit to Cardinal Stadium for a tilt with the Louisville Cardinals (4-4, 2-3) Saturday at 7:30 p.m. ET. Below, we look at the Clemson vs. Louisville odds and lines, and make our expert college football picks, predictions and bets.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Clemson defeated Florida State 30-20 last Saturday. The Tigers held the Seminoles to just 241 total yards and a combined 4-for-14 mark on third and fourth downs.

As shaky as Clemson has been offensively this season (113th FBS in yards per game and points per game), the Tigers have been solid stopping opponents. Clemson has held foes to 15.3 points per game, which ranks third nationally.

The Cardinals were on the downside of a 28-13 game at NC State last Saturday. Louisville returns home after losing three of its last four games overall. The Cards are 5-1 in their last six home games dating back to last season.

Clemson at Louisville odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10:05 a.m. ET.

  • Money line: Clemson -190 (bet $190 to win $100) | Louisville +155 (bet $100 to win $155)
  • Against the spread (ATS): Clemson -3.5, -108  | Louisville +3.5, -112
  • Over/Under (O/U): 46.5, O: -112 | U: -108

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Clemson at Louisville odds, lines, picks and predictions

Prediction

Louisville 24, Clemson 21

Money line

Clemson is perhaps getting a bit too much of a recency bias boost here. It comes after a win over a brand name Florida State, but FSU is a shaky-at-best brand in its current state. The Tigers’ offense is just simply in permanent-fade purgatory.

In points allowed vs. yardage allowed, the Clemson defense is out too far over its skis. The opposite holds true for Louisville.

BACK THE CARDINALS (+155).

Against the spread

The Tigers are 0-5 ATS in their last five games following a straight-up win.

The Cardinals are 6-0 ATS in their last six games after scoring less than 20 points in their previous game and 6-3 ATS across their last nine conference home games.

With Clemson playing its third road game in four weeks, BACK LOUISVILLE +3.5 (-112).

Over/Under

Too many reasons to not line both sides of this figure: PASS.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Colorado / Florida / Georgia / LSU / Michigan / Michigan State / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / USC / Wisconsin / College Football News

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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