Clemson Tigers betting odds line spread pick predictions best bets – Page 3

Wake Forest at Clemson odds, picks and predictions

Analyzing Friday’s Wake Forest at Clemson odds and lines, with college basketball expert picks, predictions and best bets.

The Wake Forest Demon Deacons (7-1, 0-0 ACC) and Clemson Tigers (6-2, 0-0) open their ACC play Friday at Littlejohn Coliseum. The opening tip will be at 7 p.m. ET (ACC Network Extra). Below, we analyze Tipico Sportsbook’s lines around the Wake Forest vs. Clemson odds, and make our expert college basketball picks, predictions and bets.

Wake Forest has won 3 straight games since falling 77-75 in overtime to Loyola Marymount Nov. 20. All 3 wins have been straight-up and against the number, including the Deacons’ last game when they beat the Wisconsin Badgers 78-75 as a 6-point road underdog Tuesday.

The Tigers also downed a Big Ten foe Tuesday when they covered as 2-point favorites with a 101-94 overtime win over Penn State. Clemson shot 50.8% from the floor and 52.4% from 3-point range in that win over the Nittany Lions. Since Nov. 15, the Tigers have shot 49.1% and 41%, respectively, in those categories.

Check out: USA TODAY Sports Coaches Poll

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Wake Forest at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:25 a.m. ET.

Moneyline: Wake Forest +130 (bet $100 to win $130) | Clemson -160 (bet $160 to win $100)
Against the spread (ATS): Wake Forest +2.5 (-105) | Clemson -2.5 (-115)
Over/Under (O/U): 142.5 (O: -110 | U: -110)

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Wake Forest at Clemson picks and predictions

Prediction

Clemson 72, Wake Forest 68

Moneyline

The host Tigers (-160) are a lean at the current price but really only an actionable value at -150 or better. PASS.

Against the spread

The Tigers have gone 7-2 ATS in the last 9 Wake-Clemson meetings, including 2 straight ATS wins by double-digit margins.

Clemson has played a couple of foes at the Quadrant 1 and 2 levels and is 2-0 ATS in those games (vs. Iowa Nov. 25 and vs. PSU Tuesday). The ATS win over Iowa (in a 74-71 loss) was instructive, as it was a slow (Clemson)-vs.-fast (Iowa) match-up as is this game against Wake Forest which has a top-quartile tempo number.

Clemson has 4 high-impact players that are upperclassmen. Look for the home five to log an impressive performance in this ACC lid-lifter.

BACK THE TIGERS -2.5 (-115).

Over/Under

Peg this match-up for a bit of shooting regression, but a likely exchange of Clemson points of turnovers and Wake Forest points at the line counter that regression just enough to make this a total to LAY OFF.

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South Carolina at Clemson odds, picks and predictions

Analyzing Saturday’s South Carolina at Clemson odds and lines, with college football expert picks, predictions and best bets.

The South Carolina Gamecocks (7-4) meet the No. 8 Clemson Tigers (10-1) Saturday in a non-conference tilt at Memorial Stadium in Clemson, S.C. Kickoff is scheduled for noon ET (ABC). Below, we analyze Tipico Sportsbook’s lines around the South Carolina vs. Clemson odds, and make our expert college football picks and predictions.

Rankings courtesy of AFCA Coaches Poll powered by USA TODAY sports

The Gamecocks pulled off the giant upset over then-No. 5 Tennessee last weekend, winning 63-38 as a 23.5-point underdog. South Carolina would love to spoil the CFP hopes of another rival this weekend, but it is a much taller order on the road.

Clemson leads the all-time series 72-42-4, including victories in each of the past 7 meetings. In fact, while this is an intense rivalry, lately, it hasn’t even been close. The Tigers won 30-0 in Columbia last season, and it has taken each of the past 5 in the series by at least 21 points.

The Tigers are ranked No. 7 in the College Football Playoff rankings, and need a miracle to work their way into the top 4. It helped that South Carolina won last week against Tennessee, a team Clemson was competing with for a spot in the CFP, but it hurts that North Carolina lost to NC State Friday. A win by Clemson over UNC in the ACC Championship Game won’t look nearly as impressive now.

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South Carolina at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:20 a.m. ET.

Moneyline (ML): South Carolina +440 (bet $100 to win $440) | Clemson -600 (bet $600 to win $100)
Against the spread: South Carolina +14.5 (-112) | Clemson -14.5 (-108)
Over/Under (O/U): 52.5 (O: -111 | U: -109)

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South Carolina at Clemson picks and predictions

Prediction

Clemson 33, South Carolina 24

Moneyline

Clemson (-600) will cost 6 times the potential return, and that’s way too expensive in a rivalry game. Yes, the Tigers have had their way with the Gamecocks in recent years, but South Carolina is flying high and brimming with confidence after a giant win against Tennessee last weekend.

AVOID.

Against the spread

SOUTH CAROLINA +14.5 (-112) is a good play as long as this line stays at or above two touchdowns.

In previous years, Clemson -14.5 would seem like a gift as it has dusted South Carolina by an average of 31.8 points per game in the past 5 meetings. But USC has a lot of momentum after paddling Tennessee at Williams-Brice Stadium in Columbia last weekend.

The Gamecocks might not be able to get all the way over the hump to topple the Tigers, but they should be able to keep it within 2 TDs.

Over/Under

Play OVER 52.5 (-111), but don’t expect it to be easy.

Sure, South Carolina dropped 63 on Tennessee last weekend, but that’s an anomaly. The USC offense has been rather middling this season, posting 377.9 total yards per game to rank 78th in the nation, while running for just 129.5 yards per outing to check in 96th. The offense has scored 31.7 PPG to rank 42nd overall.

Clemson is also good, but not great, on offense, going for 34.7 PPG, while allowing just 20.0 PPG. The Tigers won’t get run over like the Vols last weekend, but we should still see a healthy score into the mid-50’s here. Just go lightly.

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Louisville at Clemson odds, picks and predictions

Analyzing Saturday’s Louisville at Clemson odds and lines, with college football expert picks, predictions and best bets.

The Louisville Cardinals (6-3, 3-3 ACC) meet the No. 12 Clemson Tigers (8-1, 6-0) Saturday at Memorial Stadium in Clemson, S.C. Kickoff is scheduled for 3:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook‘s lines around the Louisville vs. Clemson odds, and make our expert college football picks and predictions.

The Cardinals posted an impressive 34-10 win over James Madison last week, winning and covering for the 4th consecutive game. Louisville’s win also clinched bowl eligibility, and it is now 6-2 against the spread (ATS) in the last 8 games.

The Tigers were shocked 35-14 on the road against Notre Dame, and it tumbled to No. 10 in the College Football Playoff rankings as a result.

Clemson’s 14 points last week was a season low, as it had 27 or more points in every previous game this season. The Tigers have failed to cover the last 2 games, and they’re 3-5 ATS in the last 8 games.

Check out: AFCA Coaches Poll powered by USA TODAY sports

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Louisville at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:27 a.m. ET.

Moneyline (ML): Louisville +220 (bet $100 to win $220) | Clemson -280 (bet $280 to win $100)
Against the spread: Louisville +7 (-112) | Clemson -7 (-108)
Over/Under (O/U): 52 (O: -110 | U: -110)

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Louisville at Clemson picks and predictions

Prediction

Clemson 33, Louisville 21

Moneyline

Clemson (-280) will cost you nearly 3 times your potential return, and that’s just too risky for a team coming off a 21-point loss last weekend.

PASS.

Against the spread

Take CLEMSON -7 (-108) laying the touchdown. Really, this could go either way. The Tigers could pout, and respond horribly to last weekend’s disappointment, or it could come back home, respond favorably, and get back on track by taking out its aggressions on Louisville +7 (-112).

I am banking on the latter, as Clemson is a well-coached team with plenty of experience, and it won’t let the disappointment of last week’s loss ruin the season. Clemson is still unbeaten in the ACC, and on track to represent the Atlantic Division in Charlotte.

Over/Under

OVER 52 (-110) is the lean, but play this very lightly.

Nearly all of the trends point to an Over result here. Clemson has cashed the Over in 5 of the last 7 games, while going 4-1 in the last 5 against teams with a winning record.

The Over has cashed in 4 of the last 5 inside the ACC for Louisville, too, while going 9-4 in the last 13 games in the month of November. The Over is 4-1 in the last 5 meetings in this series, too.

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Clemson at Notre Dame odds, picks and predictions

Analyzing Saturday’s Clemson Tigers at Notre Dame Fighting Irish odds and lines, with college football expert picks and predictions.

The No. 5 Clemson Tigers (8-0) and Notre Dame Fighting Irish (5-3) clash Saturday at Notre Dame Stadium in South Bend. Kickoff is scheduled for 7:30 p.m. ET (NBC). Below, we analyze Tipico Sportsbook‘s lines around the Clemson vs. Notre Dame odds, and make our expert college football picks and predictions.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Clemson enters this game off back-to-back, 1-score victories followed by a Week 9 bye. The Tigers, the No. 4 team in the first College Football Playoff rankings of the season, survived a somewhat shaky defensive effort in an Oct. 15 win over Florida State (34-28). They overcame 4 turnovers in an Oct. 22 victory over Syracuse (27-21).

The Fighting Irish took down Syracuse Saturday (a week after the Orange fell to Clemson). Notre Dame easily covered a 1.5-point spread in a 41-24 triumph that saw the Irish held an opposing offense under 300 total yards (286) for a 2nd straight week and a 3rd time in 4 weeks. In total defense for the season, UND ranks 28th in FBS (334.5 yards per game).

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Clemson at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 12:01 p.m. ET.

Moneyline: Clemson -190 (bet $190 to win $100) | Notre Dame +155 (bet $100 to win $155)
Against the spread (ATS): Clemson -3.5 (-110) | Notre Dame +3.5 (-110)
Over/Under (O/U): 44.5 (O: -107 | U: -115)

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Clemson at Notre Dame picks and predictions

Prediction

Clemson 24, Notre Dame 17

Moneyline

Its likely the true odds are buried between these prices. PASS.

Against the spread

The Notre Dame run defense may be a bit overrated when looking at analytic measures. Clemson has the ground game to take advantage of this deficit.

And look for the Tigers to finish on the plus side of the field and have the havoc-causing defense to produce a short field or two.

The lean, however, is small. Consider a partial-unit play on CLEMSON -3.5 (-110).

Over/Under

Both Clemson and Notre Dame figure as perhaps a bit too far over their skis in 3rd-down defense. The Irish have been awful in red-zone defense, allowing 20 TDs in as many trips.

The weather report calls for high winds, but figure both sides being able to have enough value drives to spiral this game into the 40s by the 4th quarter.

BACK THE OVER 44.5 (-107).

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Syracuse at Clemson odds, picks and predictions

Analyzing Saturday’s Syracuse at Clemson odds and lines, with college football expert picks, predictions and best bets.

The No. 14 Syracuse Orange (6-0, 3-0 ACC) and the No. 5 Clemson Tigers (7-0, 5-0) play Saturday at Memorial Stadium. Kickoff is scheduled for noon ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Syracuse vs. Clemson odds, and make our expert college football picks and predictions.

The Orange head south looking to stay unbeaten and climb to the top of the ACC Atlantic Division standings. Syracuse is coming off a 24-9 home win over NC State as a 3-point favorite last time out, moving to 5-1 ATS overall on the season.

The Tigers are not only 7-0 overall, and 5-0 inside the ACC, but they’re 4-0 in the Atlantic Division. A win here won’t quite clinch the division and punch their ticket to the ACC Championship Game, but it will move the Tigers much closer after having already topped Florida State, NC State and Wake Forest.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

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Syracuse at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:08 a.m. ET.

Moneyline (ML): Syracuse +440 (bet $100 to win $440) | Clemson -650 (bet $650 to win $100)
Against the spread (ATS): Syracuse +13.5 (-108) | Clemson -13.5 (-112)
Over/Under (O/U): 50.5 (O: -107 | U: -115)

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Syracuse at Clemson picks and predictions

Prediction

Clemson 30, Syracuse 20

Moneyline

Clemson (-650) will cost you over 6 times your potential return, and that’s just too much risk for not enough return. Syracuse usually plays the Tigers tough, so that’s even more of a problem.

AVOID.

Against the spread

SYRACUSE +13.5 (-108) heads into this one with a 5-1 ATS mark across the past 6 outings, while going 5-2 ATS in the past 7 on the road and 9-4 ATS in the previous 13 ACC games. Coach Dino Babers has this team playing well, RB Sean Tucker is a star in the making and WR Oronde Gadsden II can help spread the field.

This isn’t a boring Orange offense that has the tools to just hang for a half. Syracuse can go the whole 60 minutes and will give Clemson its most difficult test yet. If this game were in upstate New York, we might be considering an upset.

Over/Under

UNDER 50.5 (-115) is the lean here.

The Under has cashed in each of Syracuse’s past 4 ACC games and is 5-2 in its last 7 games overall.

The Over has hit in 4 of the last 5 games overall for Clemson, but the Under is 4-1-1 in its last 6 following a cover, and, more importantly, the Under has hit in 5 of the previous 6 meetings in this series.

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Clemson at Florida State odds, picks and predictions

Analyzing Saturday’s Clemson at Florida State odds and lines, with college football expert picks, predictions and best bets.

The Clemson Tigers (6-0, 4-0 ACC) visit the Florida State Seminoles (4-2, 2-2) Saturday in a classic ACC matchup. Kickoff from Doak Campbell Stadium is slated for 7:30 p.m. ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Clemson vs. Florida State odds, and make our expert college football picks and predictions.

Clemson comes into this game looking to get back to the national championship for the 1st time since 2019, and wins in games like this are key to get them into the playoffs this year. This will be their 4th straight conference game and they’ve won the previous 3 over Wake Forest (51-45 in 2 OT), NC State (30-20) and last week vs. Boston College (31-3). QB DJ Uiagalelei is still looking to silence some of his critics from last season. So far on the year he is completing 64% of his passes (122 of 190 attempts) for 1,462 yards with 14 TDs and only 2 INTs.

Florida State is looking to defeat its 1st ranked opponent this season. They started their season with 4 straight wins, but have dropped their last 2 — Oct. 1 vs. #22 Wake Forest (31-21) and last week vs. #14 NC State (19-17). QB Jordan Travis is completing 62% of his passes (98 of 156 attempts) for 1,407 yards with 9 TDs and only 3 INTs.

Clemson is No. 5 in the AFCA Coaches Poll powered by USA TODAY Sports.

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Clemson at Florida State odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 6:03 p.m. ET.

Moneyline (ML): Clemson -200 (bet $200 to win $100) | Florida State +160 (bet $100 to win $160)
Against the spread (ATS): Clemson -3.5 (-115) | Florida State +3.5 (-107)
Over/Under (O/U): 51.5 (O: -105 | U: -120)

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Clemson at Florida State picks and predictions

Prediction

Clemson 35, Florida State 14

Moneyline

BET CLEMSON -200

Though pricey, this bet is your best bet. Clemson here isn’t too heavily favored for me to believe that the risk here is not worth the reward. For this game I would bet on Clemson, even as the away team. Florida State is not an easy place to play, but Clemson is used to that type of atmosphere. Florida State is a scrappy team with a lot of talent, but this Clemson team has their eyes on a national championship, and I don’t see them losing this game.

Against the spread

BET CLEMSON -3.5 (-110)

If you’re uncomfortable with the risk of betting the moneyline in this game then this is your bet. I could very easily see Florida State putting up a fight in this game, I think the 1st half will be very close, but in the end the Tigers will show why they’re ranked 5th in the nation. The Tigers were able to beat #10 ranked NC State by 10, and that team is much better than this Florida State team. The Seminoles have proven they have some ability to score against good teams which is why I predict they will score at least 2 TDs, but that won’t be enough to make this a close game.

Over/Under

LEAN UNDER 51.5 (-120)

This is your riskiest bet. Both these offenses have the ability to score, but I have a lot of faith in Clemson’s defense to be able to string together multiple stops throughout this game. Clemson has not scored less than 30 points in any of its last 3 games, and I see that trend continuing this weekend. The only thing that worries me about this bet is the fact that Clemson allowed Wake Forest to score 45 points and NC State to score 20. While both of those teams are better than this FSU team, that causes some concern for me.

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Clemson at Boston College odds, picks and predictions

Analyzing Saturday’s Clemson at Boston College odds and lines, with college football expert picks, predictions and best bets.

The Clemson Tigers (5-0, 3-0 ACC) take on the Boston College Eagles (2-3, 1-2) Saturday. Kickoff from Alumni Stadium is scheduled for 7:30 p.m. ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Clemson vs. Boston College odds, and make our expert college football picks and predictions.

Clemson beat NC State 30-20 at home last Saturday. The game was close at halftime, with the Tigers up 13-10, but they were able to pull away in the 2nd half. QB DJ Uiagalelei went 21-of-30 passing with 209 yards and a touchdown while also carrying the ball 14 times for 73 yards and 2 TDs.

Eight different Tigers had at least 1 reception. TE Jake Briningstool led the team in receiving with 54 yards and a TD on 4 receptions. The Clemson defense stepped up forcing a fumble and making an interception, but the team hurt itself with 9 penalties for 95 yards.

The Eagles are coming off a 34-33 win at home against Louisville. QB Phil Jurkovec was 18-of-21 passing for 304 yards with 3 TDs and 1 INT. Boston College struggled in the run game with starting RB Pat Garwo III carrying the ball 12 times for only 66 yards.

Clemson is No. 5 in the AFCA Coaches Poll powered by USA TODAY Sports.

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Clemson at Boston College odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:40 a.m. ET.

Moneyline (ML): Clemson -1800 (bet $1,800 to win $100) | Boston College +1000 (bet $100 to win $1,000)
Against the spread (ATS): Clemson -20.5 (-115) | Boston College +20.5 (-107)
Over/Under (O/U): 48.5 (O: -110 | U: -110)

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Clemson at Boston College picks and predictions

Prediction

Clemson 38, Boston College 13

Moneyline

PASS.

The Clemson (-1800) moneyline is not worth the return for the risk involved in this play.

Against the spread

LEAN CLEMSON -20.5 (-115).

Barring a subpar performance including turnovers, Clemson should easily handle their business and win big.

Although 3 possessions are a lot for Clemson to cover, Boston College hasn’t performed up to par and has already suffered one blowout loss this season, 44-14 at Florida State in Week 4.

The Tigers are 5-1 ATS in their last 6 conference games and 4-1 ATS in their last 5 road games.

The Eagles are 1-6 ATS in their last 7 games overall and 1-5-1 in their last 7 home games against teams with winning records.

Over/Under

Take the OVER 48.5 (-110).

Uiagalelei and the Clemson offense have not scored fewer than 30 points in a game this season and have put up as many as 51; this is a team that is finding its offensive identity more and more each week.

Expect the Tigers to continue to put up big numbers this week. The Over is 5-1 in the Tigers’ last 6 conference games, so their AAC games have often been high-scoring battles.

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NC State at Clemson odds, picks and predictions

Analyzing Saturday’s NC State at Clemson odds and lines, with college football expert picks, predictions and best bets.

The NC State Wolfpack (4-0, 0-0 ACC) and Clemson Tigers (4-0, 2-0) meet Saturday at Frank Howard Field at Clemson Memorial Stadium. Kickoff is scheduled for 7:30 p.m. ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the NC State vs. Clemson odds, and make our expert college football picks and predictions.

NC State QB Devin Leary threw for 320 yards and 4 TDs in a 41-10 win at home vs. the UConn Huskies last Saturday. UConn RB Victor Rosa scored late in the 4th quarter as the Huskies covered the spread as 38-point underdogs.

The last time NC State left Clemson Memorial Stadium with a victory was a 38-6 win on Oct. 24, 2002.

Clemson hung on for a 51-45 2OT win at the No. 21 Wake Forest Demon Deacons last Saturday. Tigers QB DJ Uiagalelei threw for 375 yards and 5 TDs, but Clemson failed to cover the spread as 8-point favorites.

Clemson has won 36 consecutive home games.

This is the 1st time NC State and Clemson will face each other as top-10 teams.

NC State is No. 10 and Clemson 5th in the AFCA Coaches Poll powered by USA TODAY Sports.

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NC State at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 11:24 p.m. ET.

Money line (ML): NC State +240 (bet $100 to win $240) | Clemson -290 (bet $290 to win $100)
Against the spread (ATS): NC State +6.5 (+100) | Clemson -6.5 (-125)
Over/Under (O/U): 43.5 (O: -108 | U: -112)

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NC State at Clemson picks and predictions

Prediction

Clemson 20, NC State 17

Money line

PASS.

Clemson (-290) money line is too expensive, especially when NC State should make this a close game.

Against the spread

BET NC STATE +6.5 (+100).

NC State is 6-0 ATS after failing to cover the spread in its previous game. Expect the Wolfpack to also be extra focused for this matchup due to the historic nature of it and their lack of recent success at Clemson Memorial Stadium.

Over/Under

BET UNDER 43.5 (-112).

The Under is 6-1 in the last 7 head-to-head meetings in Clemson. The playoff ramifications of this matchup should also help the Under hit as both defenses will be extra focused. NC State’s defense allows just 11.8 points per game and should be able to limit Uiagalelei’s productivity.

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Clemson at Wake Forest odds, picks and predictions

Analyzing Saturday’s Clemson at Wake Forest odds and lines, with college football expert picks, predictions and best bets.

The Clemson Tigers (3-0, 1-0 ACC) and the Wake Forest Demon Deacons (3-0,0-0) meet Saturday at Truist Field in Winston-Salem, N.C. Kickoff is scheduled for noon ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Clemson vs. Wake Forest school odds, and make our expert college football picks and predictions.

The Tigers enter Saturday undefeated but have failed to cover large spreads in their last 2 outings. Clemson has allowed just 42 points across its 3 games, as the Under is 2-1 to start the year.

Wake Forest also comes in undefeated and faces a stiff test as it opens ACC play. The Demon Deacons have been one of the more prolific teams in the national on the offensive side of the ball, scoring 42 points per game to rank 21st.

Clemson is No. 5 and Wake Forest is No. 16 in the AFCA Coaches Poll powered by USA TODAY Sports.

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Clemson at Wake Forest odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6 a.m. ET.

Money line (ML): Clemson -300 (bet $300 to win $100) | Wake Forest +250 (bet $100 to win $250)
Against the spread (ATS): Clemson -7.5 (-108) | Wake Forest +7.5 (-112)
Over/Under (O/U): 55.5 (O: -110 | U: -110)

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Clemson at Wake Forest picks and predictions

Prediction

Clemson 27, Wake Forest 20

Money line

Clemson (-300) will cost you three times your potential return, and that’s risky business in a difficult road game at Wake Forest.

While Clemson has won each of its first 3 games by 23 or more points, this will easily be the most difficult opponent it has faced. The Tigers will have a chip on their shoulder after losing the Atlantic Division to the Deacs last season.

This is going to be a close game, and it’s not worth the risk for such a small return.

PASS.

Against the spread

WAKE FOREST +7.5 (-112) is the play here, especially because of the hook.

While Clemson is 4-0 ATS in its last 4 ACC games, including the Labor Day opener against Georgia Tech on a neutral field, the Tigers have just had a tough time with the Deacons for whatever reason.

Wake Forest is 7-3-1 ATS in the previous 11 meetings against Clemson in the Triad, and the Tigers are just 1-9 ATS in the past 10 appearances in September.

Over/Under

The UNDER 55.5 (-110) is worth a look here.

The Under is 5-1 in Clemson’s past 6 road games and is 22-7 in the past 29 games in September.

The Under has cashed in 7 of the last 10 home games for Wake Forest and is 9-3 in its last 12 games in September.

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Louisiana Tech at Clemson odds, picks and predictions

Analyzing Saturday’s Louisiana Tech at Clemson odds and lines, with college football expert picks, predictions and best bets.

The Louisiana Tech Bulldogs (1-1) travel to Death Valley to take on the Clemson Tigers (2-0) Saturday. Kickoff is 8 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook‘s lines around the Louisiana Tech vs. Clemson odds, and make our expert college football picks and predictions.

The Bulldogs enter the game coming off a 52-17 win against FCS school Stephen F. Austin after an opening 52-24 loss against the Missouri Tigers. QB Parker McNeil led the way with 197 yards passing along with 3 TDs while RB Marquis Crosby added 196 yards rushing and 2 TDs. WRs Tre Harris, Griffin Herbert, and Smoke Harris each had a TD reception as the Bulldogs offense totaled 515 yards. They will hope for some explosive plays to get on the board early against a much stronger Clemson team.

The Tigers beat FCS school Furman last week 35-12 after a 41-10 win over Georgia Tech in the opener. QB DJ Uiagalelei had 21 completions for 231 yards, 1 TD and 1 INT while RB Will Shipley rushed for 68 yards with 2 TDs on 10 carries. In an atypical fashion, the Tigers struggled to bury their opponent. They had 2 turnovers and gave up more yards than they gained (384-376). They also had 6 penalties for 45 yards.

Clemson has beaten Louisiana Tech the 3 times they’ve played with the last meeting in 2006.

Clemson is No. 4 in the AFCA Coaches Poll powered by USA TODAY Sports.

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Louisiana Tech at Clemson odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 8:29 a.m. ET.

Money line (ML): Louisiana Tech +2000 (bet $100 to win $,2000) | Clemson -10000 (bet $10,000 to win $100)
Against the spread (ATS): Louisiana Tech +33.5 (-112) | Clemson -33.5 (-108)
Over/Under (O/U): 53.5 (O: -112 | U: -108)

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Louisiana Tech at Clemson picks and predictions

Prediction

Clemson 45, Louisiana Tech 13

Money line

PASS. The -10000 odds will not return the rewards to make the risk worth the play.

Against the spread

LOUISIANA TECH +33.5 (-112).

The Bulldogs are a sound team coming off a game in which they were able to fine-tune their strengths. Although the Tigers will most likely separate themselves by halftime, LA Tech should be able to score enough points to cover. Furthermore, Clemson is just 1-8 ATS in September in their last 9 games.

Over/Under

UNDER 53.5 (-112).

This is not the offensive-dominant Clemson team that we have seen in previous years, rather the defense is the strong point of this team. For that reason, the under is a strong play. The under is 4-0 in the previous 4 Tigers games overall and 5-0-1 in their last 6 non-conference games.

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If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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College sports coverage from USA TODAY Sports Media Group:

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