Best NFL underdog picks and predictions for Week 3

Analyzing NFL Week 3 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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Six moneyline underdogs won their games outright in Week 2. Eight underdogs covered the spread, while 2 other games ended in a push.

For the 2nd week in a row, our 3 underdog picks went 3-0. The Arizona Cardinals covered the 5.5-point spread in a 31-28 loss to the New York Giants. The Los Angeles Rams, thanks to a last-second field goal, covered the 8.5-point spread in a 30-23 loss to the San Francisco 49ers, while the Baltimore Ravens beat the Cincinnati Bengals outright. We are 6-0 on underdog picks through 2 weeks.

Below, we analyze BetMGM Sportsbook NFL odds and lines, and tab the best NFL Week 3 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

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NFL underdog predictions: Week 3

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 11:01 a.m. ET. All games Sunday and ET unless noted.

TITANS +3.5 (-120) at Browns – 1 p.m. (CBS)

The Browns lost RB Nick Chubb for the season and QB Deshaun Watson has not looked good thus far this season.

The Titans have played 2 close games, losing by 1 point and winning by 3. They have allowed an average of only 65 rushing yards per game. The Browns have averaged 202 yards rushing a game but without Chubb and facing a tough rushing defense, it will be hard to do much offensively.

With both teams relying on the run game and their defenses, expect this to be slow, low-scoring and close.

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Eagles at BUCCANEERS +4.5 (-105) – Monday 7:15 p.m. (ABC)

The Bucs are a surprising 2-0 and are allowing only 54.0 rushing yards per game. Plus, Bucs QB Baker Mayfield has not thrown an interception yet.

The Eagles have relied on the run game (178.0 yards per game) as QB Jalen Hurts has not been as good in the pass game. The Eagles have allowed 24.0 points per game through 2 weeks.

Tampa’s defense should keep this game close.

RAMS (+125) at Bengals – Monday, 8:15 p.m. (ESPN)

QB Joe Burrow has not been good. He is averaging only 4.2 yards per passing attempt, having arguably the best trio of receivers in the league. He is also not 100%, dealing with a calf injury.

The Rams have been better than expected through 2 games. Even without WR Cooper Kupp, QB Matthew Stafford has over 300 passing yards in each game. Rookie WR Puka Nacua has 24 receptions for 266 yards in 2 games.

The Rams are No. 2 in the league in total offense. The Bengals are last.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Best NFL underdog picks and predictions for Week 2

Analyzing NFL Week 2 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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Week 1 of the NFL season usually brings surprises and last week was no different. Seven underdogs won their games outright and 9 covered the spread.

Our best underdog picks from last week went 3-0. The Detroit Lions not only covered the spread, they won outright. The Arizona Cardinals covered the 7-point spread against the Washington Commanders and the New York Jets, despite losing QB Aaron Rodgers for the season, beat the Buffalo Bills.

Let’s have similar success in Week 2.

Below, we analyze BetMGM Sportsbook’s NFL odds and lines, and tab the best NFL Week 2 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions

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NFL underdog predictions: Week 2

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 1:23 p.m. ET. All games Sunday and ET unless noted.

CARDINALS +5.5 (-105) vs. Giants – 4:05 p.m. (FOX)

We go to the Cardinals well again after they proved to be a much tougher defensive team than expected. They did to Washington what the Cowboys did to the Giants.

The Giants turned the ball over 3 times and were sacked 7 times. The Cardinals forced 3 turnovers and had 6 sacks. It looks like New York will be without LT Andrew Thomas.

I actually really like the Cardinals to win this game outright at +200, but they were so bad offensively (210 total yards and 150 excluding 2 plays on their first drive of the game) that the Giants could capitalize and squeak out a 3-point win.

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RAVENS +3.5 (-115) at Bengals – 1 p.m. (CBS)

Neither the Ravens nor the Bengals looked good in Week 1. However, Baltimore put up 25 points in a win over Houston.

The Bengals managed only 142 yards of offense in a 24-3 loss to Cleveland but it isn’t the offense that will be the reason for not covering the spread this week. They allowed Cleveland to rush for more than 200 yards.

Baltimore will be able to run the ball. The defense won’t have to shut down QB Joe Burrow like Cleveland did.

RAMS +8.5 (-115) vs. 49ers – 4:05 p.m. (FOX)

The Rams were one of the bigger surprises of Week 1, blowing out Seattle 30-13 on the road. QB Matthew Stafford had over 300 passing yards and 2 wideouts have over 100 yards, even with WR Cooper Kupp on injured reserve.

The 49ers looked dominant in their 30-7 win over Pittsburgh and have beaten the Rams in 8 straight regular-season contests, but the Rams held the Seahawks to only 85 rushing yards. Limiting RB Christian McCaffrey will keep this game close.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

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Best NFL underdog picks and predictions for Week 1

Analyzing NFL Week 1 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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The 2023 NFL season kicks off Thursday with the 1st of 16 games for the opening week. It will begin a year of surprises and upsets each week.

In 2022, underdogs won 34.3% of the games outright but were not a profitable bet overall as the underdogs on moneyline bets had a net -8.8% ROI (return on investment). However, spread bets on the underdog last season had an ROI of +6.4%.

Below, we analyze BetMGM Sportbook’s NFL odds and lines, and tab the best NFL Week 1 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

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NFL underdog predictions: Week 1

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 9:35 a.m. ET.

LIONS +4.5 (-110) at Chiefs — Thursday, 8:20 p.m. ET (NBC)

The Lions were involved in 8 games in the regular season a year ago that were decided by 4 or fewer points.

They are the favorite in the NFC North this season and face a Chiefs team, who despite being at home as the defending Super Bowl champions, will be without All-Pro DL Chris Jones, who is holding out in a contract dispute.

TE Travis Kelce, the Chiefs’ best pass catcher, is questionable with a bone bruise in his knee. While he probably plays, he won’t be 100%. I’m not quite confident enough in the +180 moneyline bet on the Lions, but they should at least keep this close down to the wire.

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CARDINALS +7 (-110) at Commanders — Sunday, 1 p.m. ET (FOX)

While the Cardinals are expected to be one of the worst teams in the NFL, the Commanders are projected to have the worst-scoring offense in the league.

The Cardinals starting defense, albeit in a handful of series in the preseason, did not allow any points. Their offense, with QB Josh Dobbs under center to start the year in place of an injured QB Kyler Murray, will likely be anemic but focused on ball control and running the football.

It will only be the 2nd NFL start for Commanders QB Sam Howell. Plus, they could be without WR Terry McLaurin, their best offensive player who has turf toe and is day to day, and DE Chase Young, their best pass rusher who has a neck injury.

This game has all the makings of a 17-13 or 16-10 stinker all over it.

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Bills at JETS (+115) — Monday, 8:20 p.m. ET (ESPN)

The Jets open at home with QB Aaron Rodgers making his debut for Gang Green. In his many years with the Green Bay Packers, he was known for some Week 1 stinkers (23-7 loss to Minnesota Vikings in 2022, 38-3 loss to New Orleans Saints in 2021), but those were always on the road.

New York has an upgraded offense with Rodgers and RB Dalvin Cook and had the No. 4 scoring defense in the league. They beat the Bills at home last season.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

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Best NFL underdog picks and predictions for Week 18

Analyzing NFL Week 18 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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We have reached the final week of the 2022 NFL season with games only on Saturday and Sunday in Week 18. In Week 17, only 4 underdogs won their games outright, but 8 dogs covered the spread.

Below, we analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 18 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

Of my 3 best underdog picks last week, 2 were correct. The Denver Broncos covered the spread against the Kansas City Chiefs and the Cleveland Browns beat the Washington Commanders outright. The Tennessee Titans did not cover against the Dallas Cowboys. 

With last week, my picks are 24-27 on the season.

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NFL underdog predictions: Week 18

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at Friday at 6:19 a.m. ET. All games Sunday and ET unless noted.

NEW YORK JETS (+115) at Miami Dolphins – 1 p.m. (FOX)

In a battle of 2 teams with 5-game losing streaks, I like the Jets. QB Mike White starts for the Jets, but the Dolphins aren’t sure who will start for them. QB Tua Tagovailoa is still recovering from a concussion and backup QB Teddy Bridgewater hurt his finger and couldn’t throw the ball to start the week.

The Dolphins have allowed 27.4 points per game in their losing streak. But that is paired with a Jets team that has averaged only 12 in their losing streak.

Something has to give and the New York defense will take advantage of the quarterback issues for Miami.

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CLEVELAND BROWNS (+120) at Pittsburgh Steelers – 1 p.m. (CBS)

The Browns have won 4 of their last 6 games and the defense has allowed only 14.0 points per game in that stretch.

The Steelers only average 17.5 points per game. They have won 3 straight and 5 of 6 but are only averaging 18.3 points per game in that stretch.

The Browns can spoil the Steelers streak of consecutive seasons without a losing record.

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TAMPA BAY BUCCANEERS +4 (-109) Atlanta Falcons – 1 p.m. (FOX)

Tampa Bay coach Todd Bowles is not planning on resting his starters although they could get pulled early. They have the No. 4 seed locked up but need to play better before the playoffs start and likely don’t want to end the regular season with a losing record.

The Falcons have only 2 wins in their last 8 games and those 2 wins came against a 3-win Chicago Bears team and a 4-win Arizona Cardinals team. They beat the Cardinals 20-19 last week on a last-second field goal and have not won a game by more than 3 points since Week 6.

More NFL Week 18 picks and predictions

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in OH, CO and NJ. Bet now!

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Best NFL underdog picks and predictions for Week 17

Analyzing NFL Week 17 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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Six underdogs picked up outright victories in Week 16 and 7 covered the spread in their games.

Below, we analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 7 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

My 3 best underdog picks went 1-2, as the Jacksonville Jaguars won their game outright as underdogs. But the Seattle Seahawks lost by 14 to the Kansas City Chiefs, failing to cover the 10.5-point spread, while the Atlanta Falcons lost by 8 when the spread was 7.5 points.

My picks are now 22-26 on the season.

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NFL underdog predictions: Week 17

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at Thursday at 11:38 a.m. ET. All games Sunday and ET unless noted.

DENVER BRONCOS +12 (-109) at Kansas City Chiefs – 1 p.m. (CBS)

The Broncos will get new life with a coaching change, which almost always brings extra focus in their 1st game.

The Broncos lost to the Chiefs by only 6 points earlier this season and 3 of the last 4 games between the 2 teams have been decided by single digits.

The Chiefs covered the spread at home for the 1st time last week against the Seahawks.

Check out: All Week 17 odds and lines

CLEVELAND BROWNS (+110) at Washington Commanders – 1 p.m. (FOX)

The Commanders are returning to QB Carson Wentz as the team has not won a game in the last month. The Commanders are 2-4 when he starts.

The Browns have lost 2 of their last 3 games but are only allowing opponents to score only 14.8 points per game in their last 5 contests.

The Commanders have not covered the spread in the last 3 weeks.

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Dallas Cowboys at TENNESSEE TITANS +12.5 (-110) – Thursday 8:15 p.m. (Prime Video)

The Cowboys are a tough team to trust. It took overtime to beat the Eagles last week with backup QB Gardner Minshew playing. They have 5 wins of more than 12 points, but only 1 in the last 5 weeks.

The Titans have lost 5 games in a row and 2 have been by at least 14 points.

The Cowboys are 3-3 ATS on the road and the Titans are 3-4 ATS at home.

It’s just too many point to lay for the Cowboys.

More NFL Week 17 picks and predictions

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in OH, CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Best NFL underdog picks and predictions for Week 16

Analyzing NFL Week 16 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

In Week 15, only 4 underdogs won their games outright. However, 9 covered the spread. That included the Indianapolis Colts, who covered the 3.5-point spread in the greatest collapse in NFL history, as they saw a 33-0 lead turn into a 39-36 overtime loss.

Below, we analyze analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 16 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

As for my underdog picks, 2 of the 3 teams covered. The Houston Texans covered the 14-point spread in a 30-24 overtime loss to the Kansas City Chiefs, the New York Giants beat the Washington Commanders 20-12 outright as 4-point underdogs, but the Tampa Bay Buccaneers lost 34-13 to the Cincinnati Bengals, failing to cover the 3.5-point spread.

Overall this season, my underdog picks are 21-24. Here we go for this week’s picks.

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NFL underdog predictions: Week 16

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at Thursday at 11:08 a.m. ET. All games Saturday and ET unless noted.

JACKSONVILLE JAGUARS (+115) at New York Jets – Thursday, 8:15 p.m. (Prime Video)

The Jaguars have won 3 of their last 4 games, including a 40-34 overtime win last week over the Dallas Cowboys. They have scored 28 or more points in those 3 wins. QB Trevor Lawrence has 7 TD passes and 1 INT in the last 2 weeks.

The Jags are 3-0-1 ATS in their last 4 games against AFC teams.

The Jets have lost 3 in a row and 4 of their last 5, averaging 13.5 points in their losses.

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SEATTLE SEAHAWKS +10 (-112) at Kansas City Chiefs – 1 p.m. (FOX)

The Chiefs have yet to cover the spread in a home game this season. They are 0-5-1 ATS on their home field.

The Seahawks have lost by double digits only once this season — in Week 2 27-7 to the NFC West champion San Francisco 49ers.

The Chiefs have won by more than 10 points only once in their last 6 games.

The Seahawks are 7th in scoring this season, averaging 25.4 points per game. They will be able to keep up with the Chiefs and their No. 1 scoring offense.

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ATLANTA FALCONS +7 (-106) at Baltimore Ravens –  1 p.m. (FOX)

The Falcons are 8-6 ATS this season and have lost by more than 7 points only once in the last 7 weeks.

Five of the Ravens’ 9 wins have been by less than 7 points. They have only 1 win in their last 5 games by more than 7.

The Ravens have not covered the spread this season at home, going 0-5-1 ATS there.

More NFL Week 16 picks and predictions

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in OH, CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

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Best NFL underdog picks and predictions for Week 15

Analyzing NFL Week 15 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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In Week 14 last week, 5 underdogs on the moneyline picked up upset wins — the Los Angeles Rams, Los Angeles Chargers, Carolina Panthers, Baltimore Ravens and Pittsburgh Steelers. Five covered the spread as underdogs.

Below, we analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 15 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

My underdog picks last week again went 1-2 as the New York Jets covered the spread against the Buffalo Bills, but the Tampa Bay Buccaneers were no match for the San Francisco 49ers and the Arizona Cardinals were beaten by the New England Patriots after QB Kyler Murray was lost for the season with a torn ACL.

On the season, my underdog picks are 19-23.

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NFL underdog predictions: Week 15

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at Thursday at 1:23 p.m. ET. All games Sunday and ET unless noted.

Kansas City Chiefs at HOUSTON TEXANS +14 (-115) –1 p.m. (CBS)

The Texans have lost by more than 14 points only once in the last 7 weeks. They lost to the Dallas Cowboys by only 4 points last week, losing a lead late in the 4th quarter.

The Chiefs are only 3-9-1 ATS on the season and managed to beat the 3-10 Denver Broncos by only 6 last week. They have 3 wins by more than 14 points but only 1 in their last 6 games.

Check out: All Week 15 odds and lines

Cincinnati Bengals at TAMPA BAY BUCCANEERS +3.5 (-110) – 4:25 (CBS)

After Tampa escaped with a win over the Saints, they were completely dominated by the 49ers 35-7. It was never close. Of course, that was going against the league’s No. 1 defense.

Cincinnati’s defense is 11th in points allowed (20.4 ppg) and 14th in yards (331.1 ypg), and they are only 20th against the pass (220.1 ypg), so QB Tom Brady will be able to get things going.

Tampa’s pass defense is 6th in the league so the Bucs will make things difficult for Joe Burrow. 

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NEW YORK GIANTS +4.5 (-110) at Washington Commanders – 8:20 p.m. (NBC)

These teams met 2 weeks ago and ended in a tie. Four of their last 5 meetings have been decided by 3 or fewer points.

The Giants have not won in their last 4 games. Washington has not lost in its last 4.

The Giants are 9-4 ATS on the season.

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

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Best NFL underdog picks and predictions for Week 14

Analyzing NFL Week 14 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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Week 13 of the NFL season was not kind to the underdog. Only 1 team, the Cincinnati Bengals, won a game outright as the underdog. A total of 6 underdogs covered the spread in Week 13.

Below, we analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 14 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

As for my picks last week, they went 1-2. The Detroit Lions covered the half-point spread, but the Tennessee Titans did not and the Miami Dolphins did not win their game.

That brings my running total for the season to 18-21.

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NFL underdog predictions: Week 14

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at Thursday at 2:03 p.m. ET. All games Sunday and ET unless noted.

TAMPA BAY BUCCANEERS +3.5 (-116) San Francisco 49ers – 4:25 p.m. (FOX)

The 49ers have the league’s No. 1 defense going against the league’s No. 26 scoring offense, as the Bucs average only 18.1 points per game.

The 49ers allow the fewest points (15.8) and the fewest yards (283.9) per game but they will now have Brock Purdy starting at quarterback in place of Jimmy Garoppolo. 

The 49ers are 9-29 with anyone other than Garoppolo starting since Kyler Shanahan became head coach.

Check out: All Week 14 odds and lines

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

NEW YORK JETS +10 (-109) at Buffalo Bills – 1  p.m. (CBS)

The Jets have not lost by double digits since Week 3. They even beat the Bills outright in Week 9.

The Bills have 5 wins this season by at least 10 points, but only 1 in the last 5 weeks (last week at New England).

The Jets have scored no fewer than 22 points with Mike White at QB the last 2 weeks. The Bills haven’t scored more than 31 since their bye week.

Play our free daily Pick’em Challenge and win! Play now!

New England Patriots at ARIZONA CARDINALS +2.5 (-112) – Monday 8:15 p.m. (ESPN)

The Patriots have not won a game when their opponent has scored 20 points or more. They have allowed 8.7 points per game in their wins and 29.0 points per game in their losses.

The Cardinals’ offense looked good in their Week 12 loss to the Los Angeles Chargers. If that carries over, they should be able to hit that 20-point mark.

In 4 of the Pats’ losses, they have allowed more than 130 rushing yards. Cardinals RB James Conner had 125 himself in the Cardinals’ loss to the Chargers.

The Cardinals are 3-1 when they rush for at least 130 yards as a team.

More NFL Week 14 picks and predictions

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

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Best NFL underdog picks and predictions for Week 13

Analyzing NFL Week 13 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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In Week 12, the underdog did not do well in terms of wins. In 16 NFL games played, only 5 underdogs on the moneyline won their games outright. However, there were 8 underdogs who covered the spread last week.

Below, we analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 13 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

I went 1-2 on my underdog picks last week, making me 17-19 on the season. The Detroit Lions kicked off the week on Thanksgiving by covering the spread, but the Houston Texans did not cover and the Arizona Cardinals did not win outright, losing to the Los Angeles Chargers by 1 point.

FOOTBALL NEVER STOPS
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NFL underdog predictions: Week 13

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at Thursday at 10:44 a.m. ET. All games Sunday and ET unless noted.

TENNESSEE TITANS +5 (-112) at Philadelphia Eagles — 1 p.m. (FOX)

The Titans are 8-3 ATS and covered the spread in 8 straight games before losing 20-16 to the Cincinnati Bengals as 1-point underdogs.

The Eagles are only 6-5 ATS this season and have failed to cover the spread in 3 of their last 4 games.

Tennessee, because of their No. 8 scoring defense and their ability to run the ball with RB Derrick Henry, they can keep any game close.

Check out: All Week 13 odds and lines

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Jacksonville Jaguars at DETROIT LIONS +0.5 (-107)  – 1 p.m. (FOX)

The Lions have covered the spread in 5 straight games and in 7 of their last 10 contests.

The Jaguars are 4-5-1 ATS in their last 10 games but are 2-0-1 ATS in their last 3.

The Jaguars have only won 1 game on the road this season.

Play our free daily Pick’em Challenge and win! Play now!

MIAMI DOLPHINS (+170) at San Francisco 49ers  – 4:05 p.m. (FOX)

The 49ers have won 4 straight games, but the Dolphins have a 5-game winning streak of their own.

The 49ers have the league’s No. 1 total defense, but face a Miami offense that has scored 30 or more in 4 straight games.

Miami’s ability to put points on the board will challenge the 49ers, especially since San Francisco’s running game has taken a hit with RB Elijah Mitchell  on injured reserve again and RB Christian McCaffrey dealing with a knee injury they have to manage.

If the Dolphins get a lead, the 49ers won’t be able to have the offensive balance that they need to win.

More NFL Week 13 picks and predictions

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Best NFL underdog picks and predictions for Week 12

Analyzing NFL Week 12 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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Thanksgiving Day means an accelerated start to Week 12, so before you sit down for some turkey and good fixings, it’s time to look at some underdog picks for the week.

Week 11 wasn’t a good week for the underdog. Only 3 underdogs — the Tennessee TitansDetroit Lions and Las Vegas Raiders — won outright, although 6 underdogs covered the spread in their losses, including the Indianapolis Colts and Carolina Panthers.

Below, we analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 12 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

All 3 of our best underdog picks from Week 11 hit — the Bears and Chargers covered the spread and the Raiders won outright — bringing our season record to 16-17.

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NFL underdog predictions: Week 12

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 11:16 a.m. ET. All games Sunday and ET unless noted.

Buffalo Bills at DETROIT LIONS +9.5 (-106) – Thursday, 12:30 p.m. ET (CBS)

The Lions have won 3 straight games and, of their 6 losses this season, they have lost by double digits only twice. Detroit has scored at least 30 points in 5 of its games and has a 6th with 27 points. It has proven the offense can keep games close.

The Bills have 4 double-digit wins, but 2 came in the first 2 weeks.

Buffalo is 5-4-1 ATS and Detroit is 6-4 ATS.

Check out: All Week 12 odds and lines

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

HOUSTON TEXANS +13 (-108) at Miami Dolphins – 1 p.m. (CBS)

The Texans have lost by more than 13 points only once this season and the Dolphins have only won by more than 13 points once.

The Texans are 1-8-1 but 4-5-1 ATS. Meanwhile, the Dolphins are 7-3 straight up and 5-5 ATS.

Play our free daily Pick’em Challenge and win! Play now!

Los Angeles Chargers at ARIZONA CARDINALS (+145) – 4:05 (CBS)

The Cardinals are expected to get QB Kyler Murray and WR Marquise Brown back this week. The Arizona offense works best when it can run the ball, which it does much better when Murray plays. The Chargers are awful against the run, ranking 30th in rushing yards allowed per game (148.4) and last in yards per carry allowed (5.5).

The Cardinals are 4-0 when opponents rush for fewer than 100 yards and 0-6 when they rush for 100 or more. The Chargers have only passed 100 rushing yards as a team twice this season.

More NFL Week 12 picks and predictions

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

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