Best NFL underdog picks and predictions for Week 15

Analyzing NFL Week 15 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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In Week 14 last week, 5 underdogs on the moneyline picked up upset wins — the Los Angeles Rams, Los Angeles Chargers, Carolina Panthers, Baltimore Ravens and Pittsburgh Steelers. Five covered the spread as underdogs.

Below, we analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 15 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

My underdog picks last week again went 1-2 as the New York Jets covered the spread against the Buffalo Bills, but the Tampa Bay Buccaneers were no match for the San Francisco 49ers and the Arizona Cardinals were beaten by the New England Patriots after QB Kyler Murray was lost for the season with a torn ACL.

On the season, my underdog picks are 19-23.

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NFL underdog predictions: Week 15

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at Thursday at 1:23 p.m. ET. All games Sunday and ET unless noted.

Kansas City Chiefs at HOUSTON TEXANS +14 (-115) –1 p.m. (CBS)

The Texans have lost by more than 14 points only once in the last 7 weeks. They lost to the Dallas Cowboys by only 4 points last week, losing a lead late in the 4th quarter.

The Chiefs are only 3-9-1 ATS on the season and managed to beat the 3-10 Denver Broncos by only 6 last week. They have 3 wins by more than 14 points but only 1 in their last 6 games.

Check out: All Week 15 odds and lines

Cincinnati Bengals at TAMPA BAY BUCCANEERS +3.5 (-110) – 4:25 (CBS)

After Tampa escaped with a win over the Saints, they were completely dominated by the 49ers 35-7. It was never close. Of course, that was going against the league’s No. 1 defense.

Cincinnati’s defense is 11th in points allowed (20.4 ppg) and 14th in yards (331.1 ypg), and they are only 20th against the pass (220.1 ypg), so QB Tom Brady will be able to get things going.

Tampa’s pass defense is 6th in the league so the Bucs will make things difficult for Joe Burrow. 

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NEW YORK GIANTS +4.5 (-110) at Washington Commanders – 8:20 p.m. (NBC)

These teams met 2 weeks ago and ended in a tie. Four of their last 5 meetings have been decided by 3 or fewer points.

The Giants have not won in their last 4 games. Washington has not lost in its last 4.

The Giants are 9-4 ATS on the season.

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Want to win your survivor pool? Who to take in Week 15

Breaking down the best strategies of how to win your NFL survivor pool as the season continues into Week 15.

NFL survivor pools are ending. A wacky year of results almost culminated in Week 14 with a Dallas Cowboys loss as 16.5-point favorites against the Houston Texans. Thank you, Lovie Smith, for bailing us out. Now we must find our way through another week of landmines and get to the promised land.

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

– All games Sunday and ET unless noted

The chalk: Kansas City Chiefs

Who they play: at Houston Texans – 1 p.m. (CBS)

We took Dallas against the Texans last week and it almost cost us. I do not see lightning striking twice. Especially with Dameon Pierce being downgraded to doubtful for this game.

If Pierce does not play, it will be hard for Houston to get anything done on offense. Brandin Cooks and Niko Collins missed last week. If both top receivers miss Week 15, the Texans will have no way to move the ball.

The Texans defense is young and they do not have the power to hold up to the likes of Patrick Mahomes and Travis Kelce. This game could get ugly quickly and coast to the end. We wish high school rules applied and we could get a running clock for the 2nd half. Kansas City is my favorite NFL Survivor Pool play in Week 15.

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Off the board: Cincinnati Bengals

Who they play: at Tampa Bay Buccaneers – 4:25 p.m. (CBS)

Tampa Bay looked terrible in a 35-7 loss to the San Francisco 49ers and Brock Purdy on Sunday. In only his 2nd game ever in the Bay Area where he grew up, Tom Brady looked like a 45-year-old QB again, something which has been happening far too often this season. Brady played his 1st game in the NFL before Purdy was even born

Coming back home to Tampa Bay will be good for the Buccaneers, but having to face the suddenly hot Bengals will not be a happy homecoming.

Despite losing WRs Tee Higgins and Tyler Boyd early in Sunday’s game against the Cleveland Browns. Cincinnati still won 23-10. Ja’Marr Chase had 10 receptions for 119 yards and 1 TD.

Joe Burrow has shown in recent weeks and in the past 2 years that he has a different demeanor then most. Joe Cool brings his game up a notch at the end of seasons and into the playoffs. With Tampa Bay on the down slide and the Bengals peaking at the perfect time, Cincinnati will go into the pirate ship and come out with its own booty. A win.

Play our free daily Pick’em Challenge and win! Play now!

Others to consider

Philadelphia Eagles: At Chicago Bears, 1 p.m. ET (FOX).

Buffalo Bills: vs. Miami Dolphins, 1 p.m. ET (NFL Network).

Want action on any of these games or other sports matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Dominick Petrillo on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

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