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The Kansas City Chiefs (9-0) renew their rivalry with the Buffalo Bills (8-2) Sunday. Kickoff from Highmark Stadium is set for 4:25 p.m. EST (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Chiefs vs. Bills odds, and make our expert NFL picks and predictions.
The Chiefs remain undefeated after cashing in a miracle last week in a 16-14 victory over the Denver Broncos. Denver rushed down the field and milked the clock to stage a 35-yard chip shot to win it as 7-point dogs, but KC blocked it to keep their streak alive. QB Patrick Mahomes threw for 266 yardsand a TD.
Buffalo won its fifth straight, covering as 4.5-point favorites in Indianapolis, to beat the Colts 30-20. QB Josh Allen was 22-for-37 for 280 yards, 0 TDs and 2 INTs, but ran in his first score in 4 weeks. RB James Cook added 80 rushing yards and a score.
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Chiefs at Bills odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated at 12:33 a.m. ET.
- Moneyline (ML): Chiefs +110 (bet $100 to win $110) | Bills -130 (bet $130 to win $100)
- Against the spread (ATS): Chiefs +2 (-110) | Bills -2 (-110)
- Over/Under (O/U): 46 (O: -110 | U: -110)
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Chiefs at Bills key injuries
Chiefs
- DE Charles Omenihu (knee) out
- RB Isiah Pacheco (ankle) out
Bills
- OT Spencer Brown (ankle) questionable
- WR Keon Coleman (wrist) out
- WR Amari Cooper (wrist) questionable
- TE Dalton Kincaid (knee) out
- LB Matt Milano (biceps) out
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Chiefs at Bills picks and predictions
Prediction
Bills 24, Chiefs 20
Moneyline
The Bills are missing a couple of key starters in Coleman and Kincaid, but Mahomes is really gimpy in the pocket with ankle and hip issues for KC. WR DeAndre Hopkins also popped up on the injury report this week with a knee issue.
This is going to be a gritty game where the running backs will be key. Allen’s legs to extend plays and get out of the pocket while Mahomes is a bit compromised physically is what turns the tables here.
You can take the Bills -130, but I prefer the spread. I would shift gears to JAMES COOK OVER 58.5 RUSHING YARDS (-120) or PATRICK MAHOMES UNDER 20.5 RUSHING YARDS (-110).
Against the spread
I’m all over BILLS -2 (-110) here. The Bills have won the last 3 regular-season meetings, but the Chiefs disposed of them in the last 3 playoff meetings. This is the number to strike at. The weather is going to be a little iffy (see below), and the running game + Allen’s legs will be the difference maker.
Over/Under
It’s expected to be in the high 40s with winds picking up to over 20 mph later in the game. There could also be light showers early on.
As such, take the UNDER 46.5 (-110). The last 5 finals in the regular season have been: 37, 44, 58, 43 and 26.
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