Iowa State at TCU odds, picks and prediction

Analyzing Tuesday’s Iowa State Cyclones at TCU Horned Frogs odds and lines, with college basketball expert picks, predictions and best bets in a Big 12 battle.

The Iowa State Cyclones (16-9, 3-9 Big 12) and TCU Horned Frogs (16-6, 5-5) are lined up for a Tuesday test in Fort Worth, Texas. The contest at Schollmaier Arena is slated to tip off at 9 p.m. ET. Below, we look at the Iowa State vs. TCU odds and lines, and make our expert college basketball picks, predictions and bets.

Iowa State dropped an overtime game to Kansas State Saturday and has lost four in a row. ISU is a defense-first team that plays in high-turnover games. Of late, the Cyclones have not shot the ball well enough to benefit from their efforts at the other end. In the losing streak, ISU has connected on just 37.7% of its looks from the field.

Texas Christian held the Cyclones to a 30.9% mark in a 59-44 win at ISU Jan. 22. TCU has dominated this series in recent seasons. The Frogs have won three in a row and eight of their last nine against Iowa State. Of late, TCU has had trouble with the turnover exchange and is just 3-3 over its last six games. Over that stretch, the Frogs’ average turnover margin is minus-4.5.

See alsoFerris Mowers Coaches Poll powered by USA TODAY Sports

Iowa State at TCU odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:34 p.m. ET.

  • Money line: Iowa State +155 (bet $100 to win $155) | TCU -190 (bet $190 to win $100)
  • Against the spread (ATS): Iowa State +3.5 (-105) | TCU -3.5 (-120)
  • Over/Under (O/U): 125.5 (O: -110 | U: -110)

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Iowa State at TCU odds, lines, picks and predictions

Prediction

TCU 62, Iowa State 60

Money line

AVOID at the current price. An Iowa State play would make sense closer to +160.

Against the spread

Across the last seven head-to-head meetings, the underdog has gone 6-1 ATS. That’s the lean here.

Iowa State is better than the results its hauling in lately. Some of that has been schedule-related, but the Cyclones were also up comfortably in their last contest before falling apart late.

Look for a solid ISU effort here. With the low-score environment, 3-and-a-hook is too many.

TAKE THE CYCLONES +3.5 (-105) on a small-to-moderate lean.

Over/Under

The pace for both teams has been on the wane of late. Figure this being a 2-by-2 battle with few 3’s and free throws. There is some ticket-cashing room on the UNDER 125.5 (-110).

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Iowa State at West Virginia odds, picks and prediction

Analyzing Tuesday’s Iowa State Cyclones at West Virginia Mountaineers odds and lines, with college basketball expert picks, predictions and best bets in a Big 12 battle..

The Iowa State Cyclones (16-7, 3-7 Big 12) visit WVU Coliseum to take on the West Virginia Mountaineers (13-9, 2-7) Tuesday. Tip-off is scheduled for 7 p.m. ET. Below, we look at the Iowa State vs. West Virginia odds and lines, and make our expert college basketball picks, predictions and bets.

The Mountaineers have lost seven in a row, recently dropping a 60-53 decision at home to then-No. 14, now-No. 9 Texas Tech Saturday. They also failed to cover as 5.5-point underdogs vs. the Red Raiders.

West Virginia is 9-13 against the spread (ATS) this season, including 2-8 ATS over its last 10 outings. G Taz Sherman, the Mountaineers’ leading scorer (18.9 points per game), missed the Texas Tech game (concussion protocol), didn’t practice Sunday and is uncertain for this contest.

Iowa State is 13-10 ATS this season and 4-6 in Big 12 play. West Virginia is the only team worse in Big 12 play ATS at 2-7.

Iowa State is led by 6-foot-4 G Izaiah Brockington, who averages team-highs in points (16.9) and rebounds (7.8). Despite his success, the Cyclones are just 2-4 straight up on the road.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Iowa State at West Virginia odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:13 a.m. ET.

  • Money line: Iowa State +105 (bet $100 to win $105) | West Virginia -130 (bet $130 to win $100)
  • Against the spread: Iowa State +1.5 (-112) | West Virginia -1.5 (-108)
  • Over/Under (O/U): 127.5 (O: -110 | U: -110)

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Iowa State at West Virginia odds, lines, picks and predictions

Prediction

Iowa State 67, West Virginia 64

Money line

BET IOWA STATE (+105).

West Virginia head coach Bob Huggins said that he hadn’t checked on Sherman’s status by Monday’s afternoon media session. That doesn’t seem like it’ll bode well for the star guard.

If that’s the case, G Sean McNeil (13.5 PPG) and F Jalen Bridges (9.0 PPG) will be tasked with leading West Virginia. If that’s the case, it’ll be tough for the Mountaineers to break their losing streak.

Despite Iowa State’s struggles on the road, it has marquee wins over now-No. 20 Texas and Texas Tech. The Cyclones are the more proven team and worth backing to win.

Against the spread

LEAN to IOWA STATE +1.5 (-112).

West Virginia has covered just 1 of its last 7. With the spread being so similar to the money line in this situation, I’d take the healthier side and side with the Cyclones to win.

Over/Under

LEAN to the OVER 127.5 (-110). This is a low total. With both teams averaging 68.0 points per game, I prefer the OVER here.

West Virginia is 12-10 O/U this season, including 8-2 in its last 10 games. In Big action, the Mountaineers are also 7-2 O/U, while the Cyclones are 5-5 O/U.

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Iowa State at Texas odds, picks and prediction

Analyzing Saturday’s Iowa State at Texas odds and lines, with college basketball expert picks, predictions and best bets.

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The No. 22 Iowa State Cyclones (16-6, 3-6 Big 12) travel to meet the No. 21 Texas Longhorns (16-6, 5-4) Saturday at the Frank Erwin Center in Austin, Texas. Tip-off is scheduled for 2 p.m. ET. Below, we look at the Iowa State vs. Texas odds and lines, and make our expert college basketball picks, predictions and bets.

The Cyclones are looking to get on track after another conference loss last time out against Kansas. Iowa State slipped to 3-6 inside the conference, and 4-6 SU after winning the first 12 games to open the season.

The Longhorns also suffered a loss in their most recent showing, falling 77-64 at Texas Tech Feb. 1. Texas has had trouble notching covers lately, going 1-5 ATS across the past six outings overall.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Iowa State at Texas odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8 a.m. ET.

  • Money line: Iowa State +320 (bet $100 to win $320) | Texas -420 (bet $420 to win $100)
  • Against the spread (ATS): Iowa State +8.5 (-112) | Texas -8.5 (-108)
  • Over/Under (O/U): 121.5 (O: -107 | U: -115)

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Iowa State at Texas odds, lines, picks and predictions

Prediction

Texas 69, Iowa State 64

Money line

Texas (-420) will cost you more than four times your potential return, and that’s just way too expensive considering the fact Iowa State (+320) won the first meeting by a 79-70 score, Jan. 15, as 2.5-point underdogs in the first meeting.

AVOID.

Against the spread

IOWA STATE +8.5 (-112) is the play catching points. The Cyclones are 5-2-1 ATS in the past eight games on the road, while going 9-3-1 ATS in the past 13 games as an underdog. One of those covers is a straight-up win over Texas -8.5 (-108) in the first meeting. Look for the Cyclones to keep it within single points.

Over/Under

The OVER 121.5 (-107) is a slam-dunk play in this Big 12 battle. The last time these teams met in Ames, Iowa, Jan. 15, the teams combined for 149 points with the total closing at 121. Scoring might not be as prolific in this one, but the game should be well Over. It’s hard to understand why the books set this one so low, but go with it.

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Kansas at Iowa State odds, picks and prediction

Analyzing Tuesday’s Kansas Jayhawks at Iowa State Cyclones odds and lines, with college basketball expert picks, predictions and best bets.

The No. 10 Kansas Jayhawks (17-3, 6-1 Big 12) and No. 22 Iowa State Cyclones (16-5, 3-5) clash in a Tuesday showdown in Ames, Iowa. Tip-off at Hilton Coliseum is slated for 7 p.m. ET (on ESPN). Below, we look at the Kansas vs. Iowa State odds and lines, and make our expert college basketball picks, predictions and bets.

Kansas dropped a non-conference home game to Kentucky 80-62 Saturday. The Wildcats outshot the Jayhawks 50.8% to 40.7% and were a plus-12 on the boards. The loss snapped a 17-game home winning streak for Kansas.

The Cyclones have won two in a row after losing four of five from Jan. 8-22. Despite Iowa State’s issues of late, it’s 3-1 over its last four home games. In a game that had four lead changes in the final 38 seconds, ISU lost at Kansas 62-61 Jan. 11 but covered the spread as a 13.5-point underdog.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Kansas at Iowa State odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:26 a.m. ET.

  • Money line: Kansas -200 (bet $200 to win $100) | Iowa State +160 (bet $100 to win $160)
  • Against the spread (ATS): Kansas -4.5 (-105) | Iowa State +4.5 (-120)
  • Over/Under (O/U): 137.5 (O: -115 | U: -107)

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Kansas at Iowa State odds, lines, picks and predictions

Prediction

Kansas 73, Iowa State 67

Money line

PASS.

Kansas is the lean, but the -200 price doesn’t make for value against the risk.

Against the spread

BACK KANSAS -4.5 (-105).

The Jayhawks are 4-0 ATS in their last four games following a double-digit loss at home. The Cyclones are 1-4 ATS in their last five home games versus teams over-.500 on the road. The favorite is 5-1 ATS in the last six meetings between these two programs, and the road team is 5-2 ATS in the last seven.

Kansas is the better shooting team, and that’s the case in the paint and beyond the arc. The Jayhawks will be plenty aware what ISU can do after last month’s meeting, and the Big 12’s fastest-paced team should bounce back with a strong effort after Saturday’s dud against Kentucky.

Over/Under

Figure an OVER 137.5 (-115) lean here, but consider a line watch. Get more value on an evenly-priced 137.5. Or see if a lower figure becomes available.

The pace numbers for both sides have climbed of late. Look for the Jayhawks to push the tempo more in this game than in the meeting in Lawrence last month.

The Over is 11-2 in the Jayhawks’ last 13 road games against teams with a winning home record.

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Missouri at Iowa State odds, picks and prediction

Analyzing Saturday’s Missouri at Iowa State odds and lines, with college basketball expert picks, predictions and best bets.

The Missouri Tigers (8-11) visit the No. 24 Iowa State Cyclones (15-5) Saturday afternoon in Ames, Iowa. The battle at Hilton Coliseum is slated to tip off at 2 p.m. ET. Below, we look at the Missouri vs. Iowa State odds and lines and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Missouri is coming off a valiant effort in a 55-54 loss to No. 2 Auburn Tuesday. Mizzou led the game at multiple points of the second half, including inside the final two minutes.

Missouri held Auburn to a 30.0% mark from the floor, and that effort fits with a recent uptick in defensive performance. Over their last four games, the Tigers have held foes to a 36.4% mark.

Iowa State defeated Oklahoma State 84-81 in overtime Wednesday. The Cyclones drained 12 3-pointers in the game, their most since Nov. 11. G Izaiah Brockington hit 3 of those treys en route to scoring 26 points. The transfer from Penn State is shooting 39.5% from beyond the arc this season.

Missouri at Iowa State odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Odds for a full list. Lines last updated at 11 a.m. ET.

  • Money line: Missouri +420 (bet $100 to win $420) | Iowa State -600 (bet $600 to win $100)
  • Against the spread (ATS): Missouri +9.5 (-102) | Iowa State -9.5 (-122)
  • Over/Under (O/U): 128.5 (O: -112 | U: -108)

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Missouri at Iowa State odds, lines, picks and predictions

Prediction

Iowa State 70, Missouri 59

Money line

Mizzou may be getting too much attention off its near-win over Auburn. Iowa State is the more talented team here and playing on its home hardwood.

It perhaps takes a different-level bankroll to leverage spots like this, but ISU figures as a near-86% win probability in this contest. That makes for value on IOWA STATE (-600).

Against the spread

In this series, the favorite is 5-1 ATS in the last six meetings. ISU is allowing just 61.0 points per game: Mizzou is 4-14 ATS in its last 18 games against team’s yielding 64-or-better.

The battle between two slower-tempo teams sets up as a low-total game, and that may scare off some would-be ISU bettors.

But the Cyclones defense feeds its offense off steals. The Tigers are prone to deficits in breakaway and second-chance points. Look for those to add up in a comfortable Iowa State victory.

BACK THE CYCLONES -9.5 (-105).

Over/Under

The listed total is in the ballpark: PASS.

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Iowa State at Oklahoma State odds, picks and prediction

Analyzing Wednesday’s Iowa State at Oklahoma State odds and lines, with college basketball expert picks, predictions and best bets.

The No. 24 Iowa State Cyclones (14-5, 2-5 Big 12) and Oklahoma State Cowboys (10-8, 3-4) will play Wednesday night in Stillwater, Okla. The game at Gallagher-Iba Arena is slated to tip at 8 p.m. ET. Below, we look at the Iowa State vs. Oklahoma State odds and lines and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Iowa State has faltered after starting the season 12-0. Three of the Cardinals’ five losses in conference play have been by double-digit margins. And, ISU has been outshot by a mile in recent weeks: since Jan. 5, the Cardinals have been outshot 47.1% to 41.6%.

Oklahoma State lost at Texas Saturday. The Cowboys beat then-No. 1 Baylor the previous Saturday (Jan. 15), but are just 4-7 since Dec. 1. OSU shot just 37.5% from the floor Saturday, and it has fired a mark under 40% in 7 of its last 8 games.

Iowa State at Oklahoma State odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Odds for a full list. Lines last updated at 2:30 p.m. ET.

  • Money line: Iowa State +145 (bet $100 to win $145) | Oklahoma State -180 (bet $180 to win $100)
  • Against the spread (ATS): Iowa State +3.5 (-110) | Oklahoma State -3.5 (-110)
  • Over/Under (O/U): 127.5 (O: -108 | U: -112)

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Iowa State at Oklahoma State odds, lines, picks and predictions

Prediction

Iowa State 63, Oklahoma State 62

Money line

Peg this one as a defensive affair, one with a lot of turnovers and not much scoring from beyond the arc. A more veteran Iowa State five has posted solid performances away from home, and there is good value in the CYCLONES (+145).

Against the spread

ISU is 8-2-1 ATS in its last 11 games as an underdog. OSU is 0-5 ATS in its last five games as a favorite.

G Bryce Williams is the Cowboys’ third-leading scorer, as he has an injury concern (questionable–leg).

OSU plays an up-tempo style. Iowa State has fared well against other fast teams this year. Against Baylor, Kansas, Iowa, Memphis, and Xavier, ISU has gone 3-2 SU and 5-0 ATS.

TAKE IOWA STATE +3.5 (-110).

Over/Under

Nothing likable in shading this figure to either side: PASS.

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Iowa State at Texas Tech odds, picks and prediction

Analyzing Tuesday’s Iowa State at Texas Tech odds and lines, with college basketball expert picks, predictions and best bets.

On Tuesday evening, the No. 14 Iowa State Cyclones (14-3) travel to United Supermarkets Arena to take on the No. 19 Texas Tech Red Raiders (13-4). Tip-off is scheduled for 9 p.m. ET. Below, we look at the Iowa State at Texas Tech odds and lines, and make our expert college basketball picks, predictions and bets.

The Cyclones are coming into this game having played a brutal conference stretch to this point. Four of their last five games have been against top-25 opponents.

They’re 2-3 overall in that stretch with losses to Baylor, Kansas and Oklahoma. They defeated Texas Tech earlier in the year at home. Iowa State is a conference-best 11-6 ATS this season.

The Red Raiders are 10-7 ATS, the second-best ATS record in the Big 12. Despite an 11-point defeat by Kansas State, they’ve beaten Baylor and Kansas, both top-ten teams, in their last four games.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Iowa State at Texas Tech odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Odds for a full list. Lines last updated Tuesday at 1:10 p.m. ET.

  • Money line: Iowa State +290 (bet $100 to win $290) | Texas Tech -380 (bet $380 to win $100)
  • Against the spread (ATS): Iowa State +8.5 (-115) | Texas Tech -8.5 (-107)
  • Over/Under (O/U): 129.5 (O: -107 | U: -115)

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Iowa State at Texas Tech odds, lines, picks and predictions

Prediction

Texas Tech 64, Iowa State 60

Money line

PASS on the money line.

Home-court advantage matters too much to bet on the upset at +290, especially with Iowa State being given 8.5 points on the spread. That’s the preferred way to bet this game.

Against the spread

BET on IOWA STATE +8.5 (-115).

Iowa State welcomed Texas Tech and beat them by 4 points earlier in the year. While Tech has a few impressive victories since then, they’ve also lost to an underwhelming Kansas State team by 11.

Both teams have seniors as three of their top four scorers, so there will be a ton of experience on the court, which should bode well for this being a close-fought game.

What the Cyclones do well is shoot from deep, averaging the fourth-most 3-pointers per game in conference play. That’s the weakness of the Red Raiders, allowing in-conference opponents to hoist up 24.4 3-pointers per game.

With Iowa State G Izaiah Brockington shooting 39% from deep, I expect him and a veteran Cyclones team to be able to keep this game within 8.

Over/Under

“LEAN” to the UNDER 129.5 (-115).

As noted, both teams are led by seniors and thrive defensively. That’s going to bode well for a slower pace, which is exactly what we saw in the 51-47 matchup in Iowa.

Both teams are 7-10 O/U this season, so it’s been profitable to bet against more points in their respective games so far.

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Iowa State at Kansas odds, picks and prediction

Analyzing Tuesday’s Iowa State Cyclones at Kansas Jayhawks odds and lines, with college basketball expert picks, predictions and best bets.

The No. 16 Iowa State Cyclones (13-2, 1-2 Big 12) and No. 10 Kansas Jayhawks (12-2, 1-1) lock horns and match wits for a ranked tussle in Lawrence, Kan. The Big 12 skirmish at Allen Fieldhouse is scheduled for an 8 p.m. ET tip-off. Below, we look at the Iowa State vs. Kansas odds and lines and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Iowa State is on the road for a second straight game after losing 79-66 at Oklahoma Saturday. ISU sports some of the best defensive numbers in the Big 12, and its 79 points allowed marked a season-high. Iowa State excels in defending the 3-ball: the Cyclones had held foes to a 24.8% mark from distance until the Sooners went 7-for-12.

The Jayhawks lead the Big 12 in scoring with 83.1 points per game, but they’re coming off a loss at Texas Tech Saturday. The defeat snapped an eight-game win streak with an average margin of nearly 19 points a game. Senior G Ochai Agbaji is shooting a career-best 47.3% on 3-point attempts and leads the conference in scoring with 20.5 PPG.

Iowa State at Kansas odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:45 a.m. ET.

  • Money line: Iowa State +470 (bet $100 to win $470) | Kansas -700 (bet $700 to win $100)
  • Against the spread (ATS): Iowa State +11.5 (-112) | Kansas -11.5 (-108)
  • Over/Under (O/U): 141.5 (O: -110 | U: -110)

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Iowa State at Kansas odds, lines, picks and predictions

Prediction

Kansas 78, Iowa State 67

Money line

Too much juice: figure the true odds as being drowned in the middle. PASS.

Against the spread

The Cyclones are 6-1-1 ATS in their last eight games as underdogs and are 4-1-1 ATS in their last six games following an ATS loss.

Iowa State is the likable side in this contest, even at Allen Fieldhouse against an angry Jayhawks squad looking to bounce back from a loss, and not because of its defense — it’s had a couple of sneakily decent offensive games of late.

While the Cyclones haven’t played a great schedule overall, they have performed well against the likes of Xavier, Memphis, Creighton, Iowa, Baylor, and Texas Tech as they’ve posted five ATS wins and an ATS loss by just 1 point.

TAKE IOWA STATE +11.5 (-112).

Over/Under

The Over is 4-1 in the Jayhawks’ last five games against teams playing .600 or better basketball and it’s 7-3 in the last 10 meetings between these Big 12 opponents.

ISU’s defensive numbers are a bit suspect because of its schedule. Look for the Jayhawks to have their tempo cranked up off a creaky non-conference home win on New Year’s Day over George Mason and two road games including a loss.

BACK THE OVER 141.5 (-110).

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Texas Tech at Iowa State odds, picks and prediction

Analyzing Wednesday’s Texas Tech Red Raiders at Iowa State Cyclones odds and lines, with college basketball expert picks, predictions and best bets.

The No. 25 Texas Tech Red Raiders (10-2, 0-0 Big 12) and No. 11 Iowa State Cyclones (12-1, 0-1) clash Wednesday in Ames, Iowa. Tip-off from James H. Hilton Coliseum is set for 9 p.m. ET. Below, we look at the Texas Tech vs. Iowa State odds and lines and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Texas Tech is 4-1 over its last five games, and its only loss during that stretch was to No. 4 Gonzaga. TTU has held foes to just 34.5% from the field over that span. The Red Raiders rank 13th in the nation with 58.2 points allowed per game.

The Cyclones rank 10th in the nation in defense with 57.1 points allowed per game. They had held foes to a minuscule 36.9% accuracy mark on field goals until dropping their first game of the season 77-72 Saturday versus Baylor. The Bears shot 50.0% from the floor and went 7-for-17 (41.2%) from distance, as Iowa State was felled for the first time under first-year head coach T.J. Otzelberger.

Texas Tech at Iowa State odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:17 a.m. ET.

  • Money line: Texas Tech +145 (bet $100 to win $145) | Iowa State -180 (bet $180 to win $100)
  • Against the spread (ATS): Texas Tech +3.5 (-107) | Iowa State -3.5 (-115)
  • Over/Under (O/U): 127.5 (O: -107 | U: -115)

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Texas Tech at Iowa State odds, lines, picks and predictions

Prediction

Iowa State 64, Texas Tech 59

Money line

The Red Raiders have played a weak schedule to date.

Iowa State has gone 4-0 while exhibiting a ton of game control against teams like Xavier, Memphis and Creighton.

Look for a versatile Cyclone backcourt to leverage a TTU weakness in defending 3-pointers.

TAKE IOWA STATE (-180).

Against the spread

The Red Raiders are 1-8 ATS in their last nine road games. The Cyclones are 7-0 ATS in their last seven games against teams playing .600 or better basketball.

The favorite has won five in a row against the number in the head-to-head series.

BACK THE CYCLONES -3.5 (-115).

Over/Under

Look for two veteran Big 12 squads to be dialed in defensively in a game with a slowed-down pace.

TAKE THE UNDER 127.5 (-115).

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Cheez-It Bowl: Clemson vs. Iowa State odds, picks and prediction

Analyzing Wednesday’s Clemson Tigers vs. Iowa State Cyclones Cheez-It Bowl odds and lines, with college football expert picks, predictions and best bets.

The No. 22 Clemson Tigers (9-3) will take on the Iowa State Cyclones (7-5) in the Cheez-It Bowl in Orlando Wednesday. Kickoff from the Camping World Stadium is set for 5:45 p.m. ET. Below, we look at the Clemson vs. Iowa State odds and lines, and make our expert college football picks, predictions and bets.

Clemson came into this season with sky-high expectations, having been one of the best programs in college football over the last few seasons. It lost 10-3 to now-No. 2 Georgia in its season opener and lost to current-No. 18 NC State 27-21 in overtime three games later.

Clemson may have had a mediocre offense, but its defense is elite. It allowed the second-fewest points in the nation (15.0 points per game). The Tigers were just 4-8 against the spread (ATS) this season, while the Cyclones were marginally better at 5-7.

While the Cyclones do have a more dynamic offense, one that features both a quarterback with over 2,800 yards and running back with over 1,400 yards, their main strength is also in their defense, one that allows the 10th fewest yards per game.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Clemson vs. Iowa State odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:48 a.m. ET.

  • Money line: Clemson -140 (bet $140 to win $100) | Iowa State +115 (bet $100 to win $115)
  • Against the spread (ATS): Clemson -2.5 (-115) | Iowa State +2.5 (-107)
  • Over/Under (O/U): 44.5 (O: -110 | U: -110)

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Clemson vs. Iowa State odds, lines, picks and predictions

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Prediction

Clemson 23, Iowa State 17

Money line

PASS. I’ll take the Clemson spread for 25 more cents on the dollar. Given that value, I’d rather play the points and wouldn’t feel comfortable enough in the Tigers to put much on a -140 money line regardless.

Against the spread

“LEAN” to CLEMSON -2.5 (-115) as its defense should be able to put it on the Cyclones offense. The Cyclones average almost 170 yards per game. Freeing up their pass game by moving the chains on the ground has been a routine for Iowa State.

They’ll be battling a Clemson rush defense that ranks ninth in the country in opponents’ rushing yards. It is a legit group with several highly-touted recruits.

Also, Cyclones leading rusher RB Breece Hall will not be playing, so that takes their offense down a huge notch.

His absence will give a huge boost to the Tigers. It must be QB Brock Purdy who gives the Cyclones any chance, and I’d rather bet for the Tigers defense than against it in this situation.

Over/Under

BET UNDER 44.5 (-110) as the Cyclones will be down their leading rusher and the Clemson offense has been inconsistent at best all season. The Clemson offense ranks 103rd in passing nationally and 56th in rushing.

Bad news for Clemson is that Iowa State has a top-25 rush defense. It should be able to limit what Clemson does best. Given Hall’s absence and the Tigers’ elite defense, I’d bank on fewer points.

Per pregame.com, we’re seeing some reverse-line movement with the vast majority of the money on the Over, but this total moving from 45 down to 44.5. The sportsbooks like their positions, and you should, too.

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and, soon, IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Colorado / Florida / Georgia / LSU / Michigan / Michigan State / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / USC / Wisconsin / College Football News

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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