First look: Los Angeles Chargers at Indianapolis Colts odds and lines

Looking at Los Angeles Chargers at Indianapolis Colts Week 16 NFL odds, lines and trends. Here’s what you need to know.

The Week 16 schedule wraps up Monday night with the Los Angeles Chargers (8-6) visiting the Indianapolis Colts (4-9-1). Kickoff is 8:15 p.m. ET at Lucas Oil Stadium (ESPN). Below, we look at Chargers vs. Colts odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Chargers beat the Tennessee Titans at home 17-14 Sunday. The game ended as a push, as the Chargers were 3-point favorites. They have won 2 games in a row and 3 of their last 4.

The Colts lost 39-36 in overtime on the road to the Minnesota Vikings, covering the 3.5-point spread. However, they blew a 33-0 lead, allowing the biggest comeback in NFL history. They have lost 4 straight games and 7 of their last 8.

Also seeAll Week 16 odds and lines

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Chargers at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:50 a.m. ET.

  • Moneyline (ML): Chargers -170 (bet $170 to win $100) | Colts +135 (bet $100 to win $135)
  • Against the spread (ATS): Chargers -3 (-117) | Colts +3 (-103)
  • Over/Under (O/U): 47.5 (O: -110 | U: -110)

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2022 betting stats

  • ML: Chargers 8-6 | Colts 4-9-1
  • ATS: Chargers 8-5-1 | Colts 6-8
  • O/U: Chargers 5-8-1 | Colts 5-9

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Chargers vs. Colts head-to-head

Dating back to 1970, the Chargers and Colts have faced one another 30 times, with the Chargers leading the all-time series 19-11.

The Chargers won the last matchup 30-24 in overtime in 2019 and have won 4 of the last 5 meetings.

This will be Chargers QB Justin Herbert’s 1st career start against the Colts.

Colts QB Matt Ryan is 2-2 in 4 career starts against the Chargers, all as a member of the Atlanta Falcons. He has 7 TD passes and 5 INTs in the 4 meetings, and he was sacked 7 times.

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First look: Indianapolis Colts at Minnesota Vikings odds and lines

Looking at Saturday’s Indianapolis Colts at Minnesota Vikings Week 15 NFL odds, lines and trends. Here’s what you need to know.

The Indianapolis Colts (4-8-1) travel to meet the Minnesota Vikings (10-3) Saturday for a Week 15 matchup. Kickoff from U.S. Bank Stadium in Minneapolis is scheduled for 1 p.m. ET (NFL Network). Below, we look at Colts vs. Vikings odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Colts are coming off a bye. Indianapolis needed a week to regroup after getting battered by a 54-19 score on the road against the Dallas Cowboys, hitting a Scoragami in the process. The Over is 3-1 in the past 4 games overall for Indy.

The Vikings were surprised on the road in Detroit, falling 34-23 as the Over hit. Minnesota is just 2-2 SU/ATS across the past 4 games overall, while the Over has hit in 3 consecutive contests.

Also see: All Week 15 odds and lines

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Colts at Vikings odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:45 a.m. ET.

  • Moneyline (ML): Colts +180 (bet $100 to win $180) | Vikings -210 (bet $210 to win $100)
  • Against the spread (ATS): Colts +4.5 (-110) | Vikings -4.5 (-110)
  • Over/Under (O/U): 46.5 (O: -110 | U: -110)

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2022 betting stats

  • ML: Colts 4-8-1 | Vikings 10-3
  • ATS: Colts 5-8 | Vikings 6-6-1
  • O/U: Colts 4-9 | Vikings 8-5

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Colts at Vikings head-to-head

These teams last met Sept. 20, 2020 in Indianapolis, a 28-11 win by the Colts. In fact, Indy has won each of the previous 4 meetings, while cover all of the victories. The Under is also a perfect 4-0 in the previous 4 meetings dating back to Sept. 14, 2008.

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First look: Indianapolis Colts at Dallas Cowboys odds and lines

Looking at Sunday’s Indianapolis Colts at Dallas Cowboys Week 13 NFL odds, lines and trends. Here’s what you need to know.

The Indianapolis Colts (4-7-1) face the Dallas Cowboys (8-3) for Sunday Night Football in Week 13. Kickoff from AT&T Stadium is scheduled for 8:20 p.m. ET (NBC). Below, we look at Colts vs. Cowboys odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Colts were on the short end of a 24-17 decision against the Pittsburgh Steelers on Monday Night Football in Week 12. After a victory at the Las Vegas Raiders in interim coach Jeff Saturday’s debut, the Colts have dropped the past two outings, both one-score games.

The Cowboys posted a 28-20 win on Thanksgiving Day over the New York Giants, moving to 4-1 SU across the past 5 outings, with no losses in regulation during the span. The Over is 3-1 in the previous 4 games overall.

Also see: All Week 13 odds and lines

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Colts at Cowboys odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 8:25 a.m. ET.

  • Moneyline (ML): Colts +380 (bet $100 to win $380) | Cowboys -475 (bet $475 to win $100)
  • Against the spread (ATS): Colts +10 (-115) | Cowboys -10 (-105)
  • Over/Under (O/U): 43.5 (O: -110 | U: -110)

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2022 betting stats

  • ML: Colts 4-7-1 | Cowboys 8-3
  • ATS: Colts 5-7 | Cowboys 7-4
  • O/U: Colts 3-9 | Cowboys 4-6-1

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Colts vs. Cowboys head-to-head

These teams last met Dec. 16, 2018, and Indianapolis posted a 23-0 win at home as a 3-point favorite as the Under connected. Dallas had won the previous 3 meetings while covering each of the outings. The Under is 3-1 in the past 4 in the series dating back to Nov. 19, 2006.

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First look: Pittsburgh Steelers at Indianapolis Colts odds and lines

Looking at Monday’s Pittsburgh Steelers at Indianapolis Colts Week 12 NFL odds, lines and trends. Here’s what you need to know.

The Pittsburgh Steelers (3-7) visit the Indianapolis Colts (4-6-1) at Lucas Oil Stadium in Week 12. The AFC foes will tussle on Monday Night Football at 8:15 p.m. ET (ESPN). Below, we look at Steelers vs. Colts odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

Pittsburgh lost 37-30 to the Cincinnati Bengals Sunday and has dropped 3 of its last 4 games. The Steelers were a 3.5-point underdog Sunday and have been an underdog in 5 of their last 6 games. Their 30 points against the Bengals marked a season-high; Pittsburgh is averaging just 17.0 points per game for the season (28th).

Also seeAll Week 12 odds and lines

The Colts dropped a 17-16 cliffhanger against Philadelphia Eagles Sunday, covering as 6.5-point underdogs. The team’s 4th loss in its last 5 games nearly was not so. Indianapolis led the contest 13-3 heading into the 4th quarter.

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Steelers at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 2:41 p.m. ET.

  • Moneyline: Pittsburgh +122 (bet $100 to win $122) | Indianapolis -155 (bet $155 to win $100)
  • Against the spread (ATS): Pittsburgh +3 (-114) | Indianapolis -3 (-106)
  • Over/Under (O/U): 39 (O: -109 | U: -111)

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2022 betting stats

  • ML: Steelers 3-7 | Colts 4-6-1
  • ATS: Steelers 4-5-1 | Colts 5-6
  • O/U: Steelers 4-6 | Colts 2-9

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Steelers vs. Colts head-to-head

The Steelers and Colts have met 7 times since 2011, and Pittsburgh is 7-0. In an overall series that dates back to 1952, the Steelers are 26-6.

Across that same 7-game stretch from above, Pittsburgh is 5-2 ATS. The Over has hit in back-to-back meetings and in 6 of the last 8.

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First look: Philadelphia Eagles at Indianapolis Colts odds and lines

Looking at Tuesday’s Philadelphia Eagles at Indianapolis Colts Week 11 NFL odds, lines and trends. Here’s what you need to know.

The Philadelphia Eagles (8-1) travel to meet the Indianapolis Colts (4-5-1) for a Week 11 matchup at Lucas Oil Stadium in Indianapolis. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we look at Eagles vs. Colts odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Eagles are looking to bounce back from their 1st loss of the season, falling 32-21 to the visiting Washington Commanders on Monday night as 11-point favorites. In that game, WR A.J. Brown rolled his ankle, although he did say he expects to be fine.

The Colts turned back to QB Matt Ryan in the much-publicized debut of Jeff Saturday as coach. Indianapolis went to Las Vegas as 4.5-point underdogs and topped the Raiders 25-20.

Also see: All Week 11 odds and lines

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Eagles at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 11:29 a.m. ET.

  • Moneyline (ML): Eagles -300 (bet $300 to win $100) | Colts +250 (bet $100 to win $250)
  • Against the spread (ATS): Eagles -6.5 (-110) | Colts +6.5 (-110)
  • Over/Under (O/U): 44 (O: -110 | U: -110)

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2022 betting stats

  • ML: Eagles 8-1 | Colts 4-5-1
  • ATS: Eagles 5-4 | Colts 4-6
  • O/U: Eagles 6-3 | Colts 2-8

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Eagles at Colts head-to-head

These teams last met in Philadelphia on Sept. 23, 2018, and the Eagles came away with a 20-16 win as the Under cashed. The Colts covered that game, and in 3 of the previous 4 meetings between the 2 sides. But the Eagles have won 3 straight in the series and the Over is 3-1 in the last 4 meetings.

Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

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First look: Indianapolis Colts at Las Vegas Raiders odds and lines

Looking at Sunday’s Indianapolis Colts at Las Vegas Raiders Week 10 NFL odds, lines and trends. Here’s what you need to know.

The Indianapolis Colts (3-5-1)and Las Vegas Raiders (2-6) will square off on Sunday as both teams try to turn around what have been very disappointing seasons. Kickoff in this AFC tilt will be at 4:05 p.m. ET (CBS) from Allegiant Stadium. Below, we look at Colts vs. Raiders odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Colts have undergone some major changes in recent weeks. They benched QB Matt Ryan for Sam Ehlinger, which hasn’t worked, and on Monday, they fired coach Frank Reich. That move came after the Colts were blown out 26-3 by the New England Patriots. The Colts have now lost 3 games in a row, scoring a total of 29 points in that stretch.

The Raiders have endured a brutally painful start to the season. They blew their 3rd 17-point lead on Sunday against the Jacksonville Jaguars, losing 27-0 on the road. That came a week after they were shut out by the New Orleans Saints 24-0. They’re now 4 games back of the Chiefs in the AFC West.

Also seeAll Week 10 odds and lines

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Colts at Raiders odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 6:48 p.m. ET.

  • Moneyline (ML): Colts +205 (bet $100 to win $205) | Raiders -260 (bet $260 to win $100)
  • Against the spread (ATS): Colts +6 (-115) | Raiders -6 (-105)
  • Over/Under (O/U): 42.5 (O: -110 | U: -110)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

2022 betting stats

  • ML: Colts 3-5-1 | Raiders 2-6
  • ATS: Colts 3-6 | Raiders 3-5
  • O/U: Colts 1-8 | Raiders 4-3-1

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Colts vs. Raiders head-to-head

The Colts and Raiders have alternated wins in their last 4 meetings, splitting those games 2-2. In their last 8 meetings, the Colts are 5-3 SU and have scored at least 20 points in each of those games.

In those same 8 games, the Raiders are 5-3 ATS. The total has gone Over 5 times in the last 8 meetings, including 4 of the last 5 games. Their most recent game was last January, which the Raiders won on the road 23-20.

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First look: Indianapolis Colts at New England Patriots odds and lines

Looking at Sunday’s Indianapolis Colts at New England Patriots Week 9 NFL odds, lines and trends. Here’s what you need to know.

The Indianapolis Colts (3-4-1) meet the New England Patriots (4-4) Sunday in Week 9. Kickoff from Gillette Stadium is set for 1 p.m. ET (CBS). Below, we look at Colts vs. Patriots odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Colts fell further behind the Tennessee Titans in the AFC South after losing 17-16 to the visiting Washington Commanders Sunday, failing to cover as 3-point favorites.

QB Sam Ehlinger made his 1st career start, completing 17-of-23 passes for 201 yards with 0 TD and 0 INT. While RB Jonathan Taylor paced the backfield with 76 yards on 16 carries, it was RB Nyheim Hines who scored Indianapolis’ only TD. Hines finished with 20 yards on 5 carries and added 29 yards on 2 receptions.

New England picked up its 3rd victory in the last 4 weeks with a 22-17 triumph over the division rival New York Jets. Covering as 2-point underdogs, the Pats improved to 4-1 ATS in the last 5 weeks.

Also see: All Week 9 odds and lines

QB Mac Jones started for the Patriots after being pulled early in their Week 7 loss to the Chicago Bears on Monday Night Football. He had 194 yards, 1 TD and 1 INT on 24-of-35 passing. RB Rhamondre Stevenson led the backfield with 71 yards on 16 carries and led all pass-catchers with 72 yards on 7 receptions. WR Jakobi Myers, who finished with 60 yards on 9 receptions, was the only other player to record more than 3 catches.

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Colts at Patriots odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:24 p.m. ET.

  • Moneyline (ML): Colts +205 (bet $100 to win $205) | Patriots -260 (bet $260 to win $100)
  • Against the spread (ATS): Colts +5.5 (-105) | Patriots -5.5 (-115)
  • Over/Under (O/U): 39.5 (O: -110 | U: -110)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

2022 betting stats

  • ML: Colts 3-4-1 | Patriots 4-4
  • ATS: Colts 3-5 | Patriots 4-3-1
  • O/U: Colts 1-7 | Patriots 4-4

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Colts vs. Patriots head-to-head

The Patriots lead the all-time series between these teams 52-30, including a 4-1 mark in the postseason. The Colts picked up a 27-17 victory in Week 15 last year, Jones’ 1st with the Patriots. That victory ended an 8-game win streak for New England, including 2 playoff meetings, but those were all during the Tom Brady era.

While the Patriots have won 8 of the last 10 meetings, they are only 5-4-1 ATS along that span. The Over has hit in 9 of those meetings, but notably the lone Under was last year’s meeting in Indianapolis.

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First look: Washington Commanders at Indianapolis Colts odds and lines

Looking at Sunday’s Washington Commanders at Indianapolis Colts Week 8 NFL odds, lines and trends. Here’s what you need to know.

The Washington Commanders (3-4) are on the road in Week 8 to take on the Indianapolis Colts (3-3-1). Kickoff is Sunday at 4:25 p.m. ET at Lucas Oil Stadium (FOX). Below, we look at Washington vs. Indianapolis odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Commanders are coming off a 23-21 upset win at home over the Green Bay Packers. They entered the game as 3.5-point home underdogs and rallied from a 14-3 deficit, holding the Packers to 232 yards of offense and not allowing them to convert a 3rd down (0-for-6) in the game.

The Colts lost on the road 19-10 to the Tennessee Titans as 2.5-point underdogs. QB Matt Ryan was intercepted twice and 1 of the picks was returned for a TD. The Indy defense held the Titans to 254 yards of offense,  but the offense only managed to gain 292.

Also see: All Week 8 odds and lines

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Commanders at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:17 a.m. ET.

  • Moneyline (ML): Commanders +165 (bet $100 to win $165) | Colts -210 (bet $210 to win $100)
  • Against the spread (ATS): Commanders +3.5 (-105) | Colts -3.5 (-115)
  • Over/Under (O/U): 41.5 (O: -108 | U: -112)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

2022 betting stats

  • ML: Commanders 3-4 | Colts 3-3-1
  • ATS: Commanders 3-4 | Colts 3-4
  • O/U: Commanders 3-4 | Colts 1-6

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Commanders vs. Colts head-to-head

This will be the 34th time the teams have faced one another, but the 1st time since 2018. The Commanders have not beaten the Colts since 2002. The Colts have won 4 straight meetings and lead the all-time series 21-12.

Washington’s last win in Indianapolis was 1994.

Ryan, in his first year as Colts QB, faced Washington 6 times as a member of the Atlanta Falcons. He is 5-1 in the 6 starts against Washington with 12 TD passes and 6 INTs.

Commanders QB Taylor Heinicke will make his 1st career start against the Colts.

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First look: Indianapolis Colts at Tennessee Titans odds and lines

Looking at Sunday’s Indianapolis Colts at Tennessee Titans Week 7 NFL odds, lines and trends. Here’s what you need to know.

The Indianapolis Colts (3-2-1) visit the Tennessee Titans (3-2) in a battle for first place in the AFC South Sunday. Kickoff from Nissan Stadium is slated for 1:00 p.m. ET (CBS). Below, we look at Colts vs. Titans odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Colts come into this game looking to extend their 2-game win streak, including a win last Sunday vs. divisional-rival Jacksonville (34-27). The Colts started their season off looking very rough, but with 2 straight wins, are bouncing back from that rough start. They are led by former NFL MVP QB Matt Ryan, who has completed 67% of his passes (170 of 253 attempts) for 1,765 yards and 8 TDs with 7 interceptions.

The Titans are coming off of a bye week, but before that, racked up 3 straight wins, after starting the season off with 2 tough losses. QB Ryan Tannehill is completing 65% of his passes (82 of 126 attempts) for 965 yards with 6 TDs and 3 interceptions.

Also seeAll Week 7 odds and lines

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Colts at Titans odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 1:30 p.m. ET.

  • Moneyline (ML): Colts +125 (bet $100 to win $125) | Titans -150 (bet $150 to win $100)
  • Against the spread (ATS): Colts +2.5 (+105) | Titans -2.5 (-130)
  • Over/Under (O/U): 42.5 (O: -115 | U: -105)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

2022 betting stats

  • ML: Colts 3-3 | Titans 3-2
  • ATS: Colts 3-3 | Titans 3-2
  • O/U: Colts 1-5 | Titans 2-3

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Colts vs. Titans head-to-head

The Colts lead the all time series 35-21, including losses in the last 4 matchups.

The Colts last win vs. the Titans came in Nov. 2020 in a 34-17 win in Tennessee. These teams have not met in the playoffs since 2000, but because they are divisional rivals, we see this matchup a lot.

The Colts are 1-4 against the spread in the last 5 matchups, and the over is 4-1 over that same span.

Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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First look: Jacksonville Jaguars at Indianapolis Colts odds and lines

Looking at Sunday’s Jacksonville Jaguars at Indianapolis Colts Week 6 NFL odds, lines and trends. Here’s what you need to know.

The Jacksonville Jaguars (2-3) travel to take on the Indianapolis Colts (2-2-1) Sunday in Week 6. Kickoff from Lucas Oil Stadium 1 p.m. ET (CBS). Below, we look at Jaguars vs. Colts odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Jaguars got off to a 2-1 start to the season before losing their last 2 games to the Philadelphia Eagles (29-21) and the Houston Texans (13-6). QB Trevor Lawrence has turned the ball over a combined 7 times in the last 2 weeks and will look to do a better job protecting the ball Sunday.

The Colts were able to squeak out a narrow 12-9 victory in Week 5 against the Denver Broncos in a game where both offenses were unable to get much going. Indianapolis will also need QB Matt Ryan to protect the football as he’s thrown 7 interceptions and fumbled the ball 11 times (3 lost).

Also seeAll Week 6 odds and lines

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Jaguars at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 8:50 a.m. ET.

  • Moneyline (ML): Jaguars +105 (bet $100 to win $105) | Colts -125 (bet $125 to win $100)
  • Against the spread (ATS): Jaguars +2.5 (-112) | Colts -2.5 (-108)
  • Over/Under (O/U): 41.5 (O: -105 | U: -115)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

2022 betting stats

  • ML: Jaguars 2-3 | Colts 2-2-1
  • ATS: Jaguars 2-3 | Colts 2-3
  • O/U: Jaguars 3-2 | Colts 0-5

Play our free daily Pick’em Challenge and win! Play now!

Jaguars vs. Colts head-to-head

This Sunday’s showdown will be the 44th meeting between the Jaguars and the Colts. Indianapolis has a 26-17 edge in the all-time matchup.

The Jaguars have had more success recently, though, winning 4 of the last 6 games in the series. Jacksonville has won 2 straight against Indianapolis and shut out the Colts 24-0 at home in Week 2.

Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Skyler Carlin on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

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