First look: Indianapolis Colts at Tennessee Titans odds and lines

Looking at Sunday’s Indianapolis Colts at Tennessee Titans Week 7 NFL odds, lines and trends. Here’s what you need to know.

The Indianapolis Colts (3-2-1) visit the Tennessee Titans (3-2) in a battle for first place in the AFC South Sunday. Kickoff from Nissan Stadium is slated for 1:00 p.m. ET (CBS). Below, we look at Colts vs. Titans odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Colts come into this game looking to extend their 2-game win streak, including a win last Sunday vs. divisional-rival Jacksonville (34-27). The Colts started their season off looking very rough, but with 2 straight wins, are bouncing back from that rough start. They are led by former NFL MVP QB Matt Ryan, who has completed 67% of his passes (170 of 253 attempts) for 1,765 yards and 8 TDs with 7 interceptions.

The Titans are coming off of a bye week, but before that, racked up 3 straight wins, after starting the season off with 2 tough losses. QB Ryan Tannehill is completing 65% of his passes (82 of 126 attempts) for 965 yards with 6 TDs and 3 interceptions.

Also seeAll Week 7 odds and lines

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Colts at Titans odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 1:30 p.m. ET.

  • Moneyline (ML): Colts +125 (bet $100 to win $125) | Titans -150 (bet $150 to win $100)
  • Against the spread (ATS): Colts +2.5 (+105) | Titans -2.5 (-130)
  • Over/Under (O/U): 42.5 (O: -115 | U: -105)

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2022 betting stats

  • ML: Colts 3-3 | Titans 3-2
  • ATS: Colts 3-3 | Titans 3-2
  • O/U: Colts 1-5 | Titans 2-3

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Colts vs. Titans head-to-head

The Colts lead the all time series 35-21, including losses in the last 4 matchups.

The Colts last win vs. the Titans came in Nov. 2020 in a 34-17 win in Tennessee. These teams have not met in the playoffs since 2000, but because they are divisional rivals, we see this matchup a lot.

The Colts are 1-4 against the spread in the last 5 matchups, and the over is 4-1 over that same span.

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