Indianapolis Colts at New England Patriots odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at New England Patriots odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts (3-4-1) hope to end a 2-game losing streak Sunday as they face the New England Patriots (4-4) on the road in Week 9. Kickoff at Gillette Stadium in Foxboro is at 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Patriots odds, and make our expert NFL picks and predictions.

The Colts lost last week 17-16 to the Washington Commanders as 3-point favorites. QB Sam Ehlinger started and passed for 201 yards without an interception, but the Commanders rallied from a 16-7 deficit with 10 points in the 4th quarter to win the game.

The Patriots beat the New York Jets 22-17 last week, covering the 3-point spread. They only had 288 yards of offense but the defense had 3 interceptions. Kicker Nick Folk made 4 field goals in the game.

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Colts at Patriots odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 11:08 p.m. ET.

  • Moneyline (ML): Colts +190 (bet $100 to win $190) | Patriots -230 (bet $230 to win $100)
  • Against the spread (ATS): Colts +5.5 (-112) | Patriots -5 (-108)
  • Over/Under (O/U): 40 (O: -110 | U: -110)

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Colts at Patriots key injuries

Colts

  • CB Tony Brown (hamstring) out
  • OL Dennis Kelly (calf, ankle) questionable
  • QB Matt Ryan (shoulder) out
  • LB Grant Stuard (pectoral)  out
  • RB Jonathan Taylor (ankle) out

Patriots

  • C David Andrews (concussion) out
  • DL Christian Barmore (knee) questionable
  • OT Marcus Cannon (concussion) out
  • S Kyle Dugger (ankle) questionable
  • RB Damien Harris (illness) questionable
  • CB Jack Jones (illness) questionable
  • WR DeVante Parker (knee) out
  • RB Pierre Strong Jr. (hamstring) questionable
  • LB Josh Uche (hamstring) questionable
  • DE Deatrich Wise Jr. (ankle) questionable

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Colts at Patriots picks and predictions

Prediction

Patriots 20, Colts 17

Moneyline

The Patriots are still not doing great offensively, but they face a Colts team without their top running back and with Ehlinger at quarterback. The Pats have won 3 of their last 4 games and have not allowed more than 17 points in the last month.

The Colts have 6 games with fewer than 20 points.

There is too much for them to overcome, but betting the Pats to win outright is too expensive.

PASS. 

Against the spread

The Pats average only 17.2 points per game with Mac Jones starting at quarterback.

However, as noted, the Colts have 6 games scoring fewer than 20 points.

Indy is No. 7 in points allowed, giving up only 19.6 per game.

It should be a low-scoring, close game that the Pats control.

BET COLTS +5.5 (-112).

Over/Under

No Taylor means an offensive struggle for the Colts and the Pats’ scoring average with Jones starting has been noted. Don’t expect a lot of points.

BET UNDER 40 (-110).

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Washington Commanders at Indianapolis Colts odds, picks and predictions

Analyzing Sunday’s Washington Commanders at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

The Washington Commanders (3-4) and Indianapolis Colts (3-3-1) play a Week 8 game Sunday at Lucas Oil Stadium in Indianapolis. Kickoff is set for 4:25 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Commanders vs. Colts odds, and make our expert NFL picks and predictions.

The Commanders have won back-to-back games to get themselves back near .500 football. Washington posted a 23-21 win over the Green Bay Packers last week as a 4-point underdog, cashing the Over in QB Taylor Heinicke‘s first start of the season. The Under was 4-0 in its previous 4 outings.

The Colts made huge headlines this week when coach Frank Reich announced veteran QB Matt Ryan would be benched for the season, with QB Sam Ehlinger taking the reins of the offense. While Ryan has been ruled out with a shoulder, Reich said Ryan would have been benched regardless.

Indianapolis is just 1 win back of the Tennessee Titans for 1st place in the AFC South, so it was a stunning move. The offense has struggled, though, scoring 20 or fewer points in 6 of 7 games overall. It’s no surprise the Under is 6-1 to date.

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Commanders at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 10:08 a.m. ET.

  • Moneyline (ML): Commanders +125 (bet $100 to win $125) | Colts -150 (bet $150 to win $100)
  • Against the spread: Commanders +2.5 (+100) | Colts -2.5 (-125)
  • Over/Under (O/U): 39.5 (O: -115 | U: -105)

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Commanders at Colts key injuries

Commanders

  • WR Dyami Brown (groin) questionable
  • OL Saahdiq Charles (illness) questionable
  • WR Jahan Dotson (hamstring) out
  • LB Cole Holcomb (foot) out
  • CB William Jackson (back) out
  • TE Logan Thomas (calf) questionable

Colts

  • DL Kwity Paye (ankle) out
  • QB Matt Ryan (shoulder) out
  • CB Kenny Moore (finger) questionable

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Commanders at Colts picks and predictions

Prediction

Colts 23, Commanders 19

Moneyline

The Colts (-150) aren’t too highly-priced, but there are plenty of questions on how this offense will look with Ehlinger under center. Of course, it couldn’t be much less productive than the first 7 games under Ryan’s direction.

Still, I don’t like the value on Indy here straight up, and I don’t like the Commanders (+125), either. Washington has too many key players like Dotson, Holcomb and Jackson in street clothes.

AVOID.

Against the spread

The COLTS -2.5 (-125) are worth playing lightly, with a max bet of a half-unit. There are just too many unknowns with Ehlinger making his first start, and he is sure to be nervous, at least initially.

The good news is that he won’t have Holcomb gumming up the works in the middle, so RB Jonathan Taylor should finally be able to get going, opening up the passing game a little bit.

Over/Under

OVER 39.5 (-115) is also worth playing lightly.

This is a very low number for the NFL, but this is a game that features Heinicke vs. Ehlinger at the quarterback position. It isn’t expected to be a track meet by any means.

Still, we do have the likes of RB Brian Robinson and WR Terry McLaurin on one side, and Taylor and WR Michael Pittman Jr. on the other. There is the potential for plenty of points if the quarterbacks can do their jobs.

More NFL Week 8 picks and predictions

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Indianapolis Colts at Tennessee Titans odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Tennessee Titans odds and lines, with expert NFL picks, predictions and best bets.

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The Indianapolis Colts (3-2-1) visit Nissan Stadium Sunday to face the Tennessee Titans (3-2). Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Titans odds, and make our expert NFL picks and predictions.

Last week, the Colts beat the Jacksonville Jaguars 34-27 as 1-point favorites. They started slow, trailing 21-19 after 3 quarters, but outscored the Jaguars 15 to 6 in the final quarter. QB Matt Ryan‘s play helped make up for the absence of RB Jonathan Taylor (ankle). Ryan threw for 389 yards and 3 touchdowns, completing 42 of 58 pass attempts. His top receiver was WR Michael Pittman Jr., who had 13 receptions for 134 yards. Seven receivers who caught a ball from Ryan had at least 3 receptions each. The defense finished with 4 sacks and forced a fumble in the win.

The Titans are coming off a bye week, previously winning at the Washington Commanders 21-17 in Week 5. In that game, RB Derrick Henry had 28 carries for 102 yards and 2 TDs, while QB Ryan Tannehill went 15 of 25 for 181 passing yards and a TD. Seven Titans had at least 1 reception. Tennessee was outgained in total yards 385 to 241, but Henry proved to be the X-factor. The defense had 3 sacks and forced an interception in the victory. Expect the Titans’to utilize Henry just as much Sunday coming off of a week of rest.

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Colts at Titans odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:08 a.m. ET.

  • Moneyline (ML): Colts +117 (bet $100 to win $117) | Titans -140 (bet $140 to win $100)
  • Against the spread (ATS): Colts +2.5 (-103) | Titans -2.5 (-117)
  • Over/Under (O/U): 42.5 (O: -108 | U: -112)

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Colts at Titans key injuries

Colts

  • LB Shaquille Leonard (concussion, nose, back) out
  • DE Kwity Paye (ankle) out

Titans

  • LB Zach Cunningham (elbow) out
  • OL Nate Davis (foot) out
  • WR Kyle Phillips (hamstring) questionable

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Colts at Titans picks and predictions

Prediction

Titans 20, Colts 17

Moneyline

TAKE THE TITANS (-140).

Coming off a bye week, expect Tennessee to be at full strength, giving Henry the necessary rest to continue his dominant season thus far. Coach Mike Vrabel will have the team ready to compete at home against a Colts squad that has yet to prove itself.

Against the spread

LEAN TITANS -2.5 (-117).

Scoring 92% of the time they are in the red zone and only giving up points 50% of the time the opposing offense is in the red zone is a recipe for success for the Titans. With offensive weapons in WR Robert Woods and Henry, they have the ability to get into scoring range quickly. Barring a massive game in Taylor’s return from injury, lean Titans ATS.

Furthermore, the Titans are 6-0 ATS in their last 6 games in October and the favorite is 14-6 ATS in these teams’ last 20 meetings. The Colts are also 0-4 ATS in the last 4 meetings between these two.

Over/Under

Bet the UNDER 42.5 (-112).

All the trends in this one point toward taking the Under.

The Under is 6-0 in the Colts’ last 6 road games, 4-0 in their last 4 on grass, and 4-0 in their last 4 against a team with a winning record.

For the Titans, the Under is 8-1 in their last 9 games on grass and 4-0 in their last 4 games following a straight-up win.

The Under is 5-1 for the Colts this season and 3-2 for the Titans. Expect a run-heavy game between Taylor and Henry which will accumulate to the clock ticking away constantly.

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Jacksonville Jaguars at Indianapolis Colts odds, picks and predictions

Analyzing Sunday’s Jacksonville Jaguars at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

The Jacksonville Jaguars (2-3) take their 2-game losing streak into Lucas Oil Stadium to face division rival the Indianpolis Colts (2-2-1) Sunday at 1 p.m. ET. (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Jaguars vs. Colts odds, and make our expert NFL picks and predictions.

When the Colts got rid of QB Carson Wentz and added Matt Ryan, they were hoping the team would get better. It has been a struggle so far.

Coming off a 12-9 overtime victory at the Denver Bronos in the Week 5 Thursday night game, the offense has not found its way yet. While the low-scoring output can be chalked up to RB Jonathan Taylor being out with an ankle injury, the same cannot be said for Indy’s other games this season. The Colts were shut out 24-0 at Jacksonville in Week 2 when Taylor was healthy.

The Jaguars have been dismal the last 2 weeks after winning 2 games that weren’t even close – the 24-0 win over the Colts and a Week 3 win at the Los Angeles Chargers 38-10. QB Trevor Lawrence has regressed a bit since his hot start. However, his connection with WR Christian Kirk and the run game of RB James Robinson have been lacking in the recent losses.

Look for a slow, low-scoring game in Indianapolis.

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Jaguars at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:17 p.m. ET.

  • Moneyline (ML): Jaguars +110 (bet $100 to win $110) | Colts -140 (bet $140 to win $100)
  • Against the spread (ATS): Jaguars +2.5 (-108) | Colts -2.5 (-112)
  • Over/Under (O/U): 42.5 (O: -108 | U: -112)

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Jaguars at Colts key injuries

Jaguars

  • LB K’Lavon Chaisson (knee) out

Colts

  • RB Nyheim Hines (concussion) questionable
  • C Ryan Kelly (hip) questionable
  • LB Shaquille Leonard (concussion) questionable
  • DE Kwity Paye (ankle) questionable
  • RB Jonathan Taylor (ankle) questionable

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Jaguars at Colts picks and predictions

Prediction

Colts 20, Jaguars 14

Moneyline

PASS. The Colts (-130) are a good bet here, but I like the ATS better.

Against the spread

TAKE COLTS -2.5 (-112).

The Colts always have a tough time against the Jaguars in Jacksonville, but this game is in Indianapolis, and it should be an easier time. If Taylor sits again, I would certainly not take this number. But with him being healthy and Ryan hopefully finding a connection with his receivers, I like the Colts here against the Jaguars secondary.

Over/Under

TAKE UNDER 42.5 (-112) in this game.

Games in this rivalry tend to be low scoring and run heavy. That wil be the case here with the 2 best players in this game likely to be Taylor and Robinson. The clock will wind, and points will be at a premium. Look for another Under to hit here. This is my FAVORITE PLAY of the game.

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Indianapolis Colts at Denver Broncos odds, picks and predictions

Analyzing Thursday’s Indianapolis Colts at Denver Broncos odds and lines, with expert NFL picks, predictions and best bets.

Indianapolis Colts (1-2-1) face the Denver Broncos (2-2) at Empower Field at Mile High Thursday. Kickoff is at 8:15 p.m. ET (Prime Video). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Broncos odds, and make our expert NFL picks and predictions.

Week 5 is here and that’s long enough to make a semi-accurate analysis of teams. Both the Colts and Broncos have fallen short of their expectations.

The Colts lost 24-17 to the Tennessee Titans in Week 4. They’ve played each team in the AFC South and couldn’t pick up a single win. RB Jonathan Taylor was held to 42 rushing yards on 20 carries in the Week 4 defeat and suffered an ankle injury that will keep him sidelined Thursday.

The Broncos had a relatively easy schedule to start the season and yet sit 2-2, trailing the division-leading Kansas City Chiefs. Denver has put up 16, 16, 11 and 23 points to start the season. RB Javonte Williams has been ruled out for the season after suffering an ACL injury in Week 4.

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Colts at Broncos odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:45 a.m. ET.

  • Moneyline (ML): Colts +150 (bet $100 to win $150) | Broncos -180 (bet $180 to win $100)
  • Against the spread (ATS): Colts +3.5 (-117) | Broncos -3.5 (-103)
  • Over/Under (O/U): 42.5 (O: -108 | U: -112)

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Colts at Broncos key injuries

Colts

  • Julian Blackmon (ankle) out
  • LB Shaquille Leonard (concussion, nose, back) out
  • RB Jonathan Taylor (ankle) out

Broncos

  • LB Jonathan Cooper (hamstring) out
  • OL Quinn Meinerz (hamstring) out
  • OL Billy Turner (knee) questionable
  • RB Javonte Williams (ACL) out

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Colts at Broncos picks and predictions

Prediction

Colts 21, Broncos 17

Moneyline

This game is a toss-up.

The Colts won’t have Taylor but RB Nyheim Hines is more than capable of handling the extra workload, and we don’t know if coach Nathaniel Hackett will sabotage his own team again in Denver.

I would AVOID.

Against the spread

Both the Colts and Broncos are 1-3 ATS putting them in the bottom 3rd of the NFL. However, 3.5-points is a large number in the NFL, especially with QB Russell Wilson unable to get the Broncos’ offense moving. Expect the Colts to keep things close or even pull off the upset.

LEAN COLTS +3.5 (-117).

Over/Under

The Colts have hit the Under in each of their games this year and in 9 straight games dating back to last season.

The Broncos went Under in 3 of their first 4 games. Denver’s defense is still formidable and scoring will be a tough task for Indianapolis.

BET UNDER 42.5 (-112).

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Tennessee Titans at Indianapolis Colts odds, picks and predictions

Analyzing Sunday’s Tennessee Titans at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

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The Tennessee Titans (1-2) visit the Indianapolis Colts (1-1-1) Sunday in an AFC South clash. Kickoff from Lucas Oil Stadium is set for 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Titans vs. Colts odds, and make our expert NFL picks and predictions.

The Titans come into this game off their 1st win of the season last week against the Las Vegas Raiders, 24-22. Tennessee hasn’t looked like the team we would normally expect it to, and in what many are calling the worst division in football, it’s yet to find its groove.

QB Ryan Tannehill has not looked very good at this point of the season, completing just 62.5% of his passes while only throwing 3 touchdowns to 3 interceptions. Many Titans fans are calling for rookie QB Malik Willis to be named the starter, but Tannehill hopes to prove them wrong this week.

The Colts also clinched their only win of the season last week in a huge 20-17 victory over the Kansas City Chiefs. Many are calling this a fluke game and the Colts look to get a huge divisional win and save their season before it’s too late.

QB Matt Ryan has not looked like his former MVP self at this point of the season. He is completing 64.1% of his passes and has only thrown 3 touchdowns so far, but has thrown 4 interceptions. Colts fans expected much more when signing Ryan after moving on from an underwhelming 2021 season with QB Carson Wentz.

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Titans at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 11:05 a.m. ET.

  • Moneyline (ML): Titans +160 (bet $100 to win $160) | Colts -190 (bet $190 to win $100)
  • Against the spread (ATS): Titans +3.5 (-110) | Colts -3.5 (-110)
  • Over/Under (O/U): 43.5 (O: -105 | U: -120)

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Titans at Colts key injuries

Titans

  • LB Zach Cunningham (elbow) out
  • Amani Hooker (concussion) questionable
  • LB Harold Landry III (knee) injured reserve
  • OL Taylor Lewan (knee) injured reserve
  • CB Roger McCreary (back) questionable

Colts

  • Julian Blackmon (ankle) out
  • DL DeForest Buckner (elbow) questionable
  • LB Shaquille Leonard (back) questionable

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Titans at Colts picks and predictions

Prediction

Titans 24, Colts 17

Moneyline

AVOID.

There is no clear favorite in a game like this and I would advise avoiding the money line. Both teams have injuries and neither team has lived up to their preseason expectations at this point of the season. Both offenses have looked mediocre and neither defense has looked impressive.

Against the spread

LEAN TITANS +3.5 (-110).

Odd makers have the Colts set as the favorite for this weekend because of their win last week vs. the Chiefs. However, I believe last week’s win was a fluke game.

The Colts offense has looked terrible at this point in the season, even being shutout by the Jacksonville Jaguars in week 2. They rank 32nd in points per game (13.3). Their defense has been mediocre and their offense has not looked good enough to beat the Titans by margin in my eyes.

Over/Under

BET UNDER 43.5 (-120).

In a game where the brightest spot for 2 struggling teams is the running backs, don’t expect a high-scoring finish. Neither QB has proven that they can put up points when needed in 2022, and neither defense looks terrible yet either.

Neither team has scored more than 22 points in a game this year, and I wouldn’t be surprised if that trend remains true this weekend. Besides the Titans’ Week 2 game against the Buffalo Bills, neither team has let up an outrageous amount of points. I expect the under to be the safest play for this game.

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Kansas City Chiefs at Indianapolis Colts odds, picks and predictions

Analyzing Sunday’s Chiefs at Colts odds and lines, with expert NFL picks, predictions and best bets.

The Kansas City Chiefs (2-0) take on the Indianapolis Colts (0-1-1) Sunday at Lucas Oil Stadium for a 1 p.m. ET kickoff (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Chiefs vs. Colts odds, and make our expert NFL picks and predictions.

The undefeated Chiefs are coming off a 27-24 Thursday night win over the AFC West rival Los Angeles Chargers. QB Patrick Mahomes has led the way to K.C.’s 2 victories by throwing for 595 yards and 7 TD while not yet throwing an INT. The Chiefs’ offense is tied for 2nd with the Detroit Lions in points per game with 35.5, just behind the Buffalo Bills (36 PPG).

The winless Colts scored 0 points against the Jacksonville Jaguars in Week 2. QB Matt Ryan has thrown 4 INT this season (tied for 2nd most in the league), although he was without WRs Michael Pittman and Alec Pierce last week due to injuries.

Indy won its last matchup against the Chiefs in 2019 and leads the overall series 17-10. Ryan is 0-2 against the Andy Reid-coached Chiefs in his career.

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Chiefs at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 9 a.m. ET.

  • Money line (ML): Chiefs -240 (bet $240 to win $100) | Colts +200 (bet $100 to win $200)
  • Against the spread (ATS): Chiefs -5.5 (-115) | Colts +5.5 (-105)
  • Over/Under (O/U): 50.5 (O: -115 | U: -105)

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Chiefs at Colts key injuries

Chiefs

  • K Harrison Butker (ankle) out
  • DE Mike Danna (calf) out

Colts

  • LB Shaquille Leonard (back) out
  • DE Yannick Ngakoue (back) questionable

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Chiefs at Colts picks and predictions

Prediction

Chiefs 41, Colts 20

Money line

This should be a win for the Chiefs who have beaten much tougher competition this season. It’ll be near impossible for the Colts, who have averaged 10 points per game (worst in the NFL), to keep up with one of the league’s top offenses. Equipped with that knowledge, you should include the CHIEFS (-240) into any NFL parlay that you plan to play in Week 3.

Against the spread

Again, CHIEFS -5.5 (-115) is a no-brainer. Winning by more than a TD is more than doable for a team that is tied for the second-most TDs (9) in the league.

Over/Under

The Over/Under is tricky for this game because it depends on defense as well, not just offense. We know the Chiefs will put up points, but how much will they allow? Recent play suggests the Colts won’t score much, but they’re returning Pittman from injury and the Chiefs are missing one of their top run-stoppers in LB Willie Gay due to suspension. That means the Colts could hypothetically score more points than previous weeks, even if it comes during garbage time.

I would AVOID the Over/Under for this matchup and stick to the spread and money line.

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If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Indianapolis Colts at Jacksonville Jaguars odds, picks and predictions

Analyzing Sunday’s Colts at Jaguars odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts (0-0-1) and Jacksonville Jaguars (0-1) continue their AFC South rivalry Sunday at TIAA Bank Field in Jacksonville, Fla. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Jaguars odds, and make our expert NFL picks and predictions.

The Colts tied the Houston Texans 20-20 in Week 1 after both squads failed to score in overtime. QB Matt Ryan had a solid day with 352 yards passing, 1 TD and 1 INT. He found WR Michael Pittman Jr. for 121 of those yards on 9 receptions. RB Jonathan Taylor continued to show why he’s the NFL’s top back, earning 161 yards and a TD on 31 carries.

The Jaguars lost on the road last week 28-22 to the Washington Commanders. Jacksonville led 22-14 in the 4th quarter, but allowed 14 unanswered points in the final 10 minutes. Second-year QB Trevor Lawrence passed for 275 yards and 1 TD and 1 INT. His favorite target was newly-acquired WR Christian Kirk, who had 6 receptions for 117 yards.

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Colts at Jaguars odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:26 a.m. ET.

  • Money line (ML): Colts -165 (bet $165 to win $100) | Jaguars +140 (bet $100 to win $140)
  • Against the spread (ATS): Colts -3.5 (+102) | Jaguars +3.5 (-125)
  • Over/Under (O/U): 44.5 (O: -112 | U: -108)

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Colts at Jaguars key injuries

Colts

  • WR Alec Pierce (concussion) out
  • WR Michael Pittman Jr. (quad) out
  • DT DeForest Buckner (hip) questionable
  • CB Kenny Moore II (hip) questionable

Jaguars

  • None

[the_huddle]

Colts at Jaguars picks and predictions

Prediction

Jaguars 24, Colts 20

Money line

If you’re ever going to play Jacksonville as an underdog, right now may be the perfect time to do it. The Colts are already banged up just 2 weeks into the season, missing 2 of their top WRs in Pittman and Pierce. They’ll rely on the running game with Taylor, but that 1-dimensional offensive approach may not be enough to take out the Jags on the road.

I like the JAGUARS +140.

Against the spread

If you’re not quite sold on taking the Jags straight up, that’s okay. Play the JAGUARS +3.5 (-125). Both matchups from each squad last week suggest they’ll play teams close, plus this is a divisional matchup where each team will throw out its best. Recent history shows the Jags should cover as well — they’re 4-0 ATS vs. the Colts in their last 4 matchups.

Over/Under

I try to avoid over/unders on total points at the beginning of the season until teams and trends are more established. That said, if you’re dying to put something down on this, I’d lightly lean toward UNDER 44.5 (-108) for the sole fact that neither offense appears to be that good (yet). The Colts will run the ball more which means draining more clock, while the Jaguars have yet to do anything to show that their offense can consistently put up big points.

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Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Indianapolis Colts at Houston Texans odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Houston Texans Week 1 odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts and Houston Texans open their seasons Sunday at NRG Stadium. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Texans odds, and make our expert NFL picks and predictions.

The Colts finished the 2021 season with a 26-11 loss at the Jacksonville Jaguars in Week 18 as 14-point favorites that resulted in them missing the playoffs. Indianapolis then brought in QB Matt Ryan from the Atlanta Falcons to replace QB Carson Wentz under center.

Indianapolis is the favorite to win the AFC South at -135. Colts star RB Jonathan Taylor is the favorite to finish the regular season with the most rushing yards at +425 and co-favorite with Los Angeles Rams WR Cooper Kupp to win Offensive Player of the Year at +900.

Houston is clearly in a rebuild after only winning 4 games last season. However, the Texans covered the spread in 3 of their final 4 games, including a 41-29 win as 13.5-point underdogs vs. the Los Angeles Chargers in December.

Houston QB Davis Mills finished his rookie campaign with 16 TD and 10 INT. Houston is the favorite at +300 to finish with the worst record in the NFL.

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Colts at Texans odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 7:38 a.m. ET.

  • Money line (ML): Colts -340 (bet $340 to win $100) | Texans +270 (bet $100 to win $270)
  • Against the spread (ATS): Colts -7.5 (+100) | Texans +7.5 (-120)
  • Over/Under (O/U): 45.5 (O: -112 | U: -108)

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Colts at Texans key injuries

Colts

  • LB Shaquille Leonard (ankle) probable

Texans

  • None

[the_huddle]

Colts at Texans picks and predictions

Prediction

Colts 28, Texans 21

Money line

PASS.

The Colts (-340) should win, but the price is too high to bet the money line. While Indianapolis is the better team, Houston showed at the end of last season that it is capable of upsetting big favorites.

Against the spread

Indianapolis has a better roster than Houston, but this will be Ryan’s first regular season game with the Colts. Mills has had the time to build chemistry with his receivers that Ryan hasn’t had.

Houston is undervalued in this spot considering its offense can build on the chemistry it flashed at the end of last season.

BET THE TEXANS +7.5 (-120).

Over/Under

The Under is 5-0 in the last 5 head-to-head meetings between these teams, but those were under different circumstances. Indianapolis’ offense should be much more productive with former MVP Ryan acting as signal-caller, while Houston’s offense should have drastically improved since the most recent head-to-head meeting last December.

BET OVER 45.5 (-112).

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More NFL Week 1 coverage

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Tampa Bay Buccaneers at Indianapolis Colts odds, picks and predictions

Analyzing Saturday’s Tampa Bay Buccaneers at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

The Tampa Bay Buccaneers (0-2) and Indianapolis Colts (0-2) both wrap up their 2022 preseason schedule Saturday night. They kick off at 7:30 p.m. ET at Lucas Oil Stadium. It will be televised regionally in the home viewing market of each team. Below, we analyze Tipico Sportsbook‘s lines around the Buccaneers vs. Colts odds, and make our best NFL picks, predictions and bets.

The Bucs lost their preseason opener, 26-24, to the Miami Dolphins. They outgained Miami 389 yards to 242 but turned the ball over twice. They followed that up with a 13-3 loss to the Tennessee Titans.

The Colts dropped their preseason opener 27-24 to the Buffalo Bills. The Colts forced 5 turnovers in the game. In their 2nd game, they also lost a close one, 27-26, to the Detroit Lions.

Buccaneers at Colts odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 1:30 p.m. ET.

  • Money line (ML): Buccaneers +155 (bet $100 to win $155) | Colts -190 (bet $190 to win $100)
  • Against the spread (ATS): Buccaneers +3.5 (-115) | Colts -3.5 (-105)
  • Over/Under (O/U): 40.5 (O: -117 | U: -103)

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Buccaneers at Colts picks and predictions

Prediction

Buccaneers 24, Colts 21

Money line

Preseason games tend to be tossups, especially when starters are held out of games. You are left with backups and players that largely won’t be on NFL rosters deciding games.

Is there anything we can take away from the teams’ first 2 preseason contests that help us pick tonight’s outcome? Not really, other than both teams can score and give up points.

So for preseason games, if you are going to wager, go with the best value since it is a tossup. Take the BUCCANEERS (+155).

Against the spread

The Bucs have lost by 2 and by 10. The Colts have lost by 3 and by 1.

Does that tell us anything?

Well, when it is Kyle Trask and Jack Coan deciding games, no.

With a small spread and the variant nature of the preseason, PASS on the spread.

[the_huddle]

Over/Under

Here we can make a somewhat educated pick. The Bucs’ last game only had a total of 16 points, but their preseason opener and both games the Colts have played had more than 50 total points.

Take OVER 40.5 (-117).

This total came down a point Saturday and remains at a value.

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