Indianapolis Colts betting odds line spread pick predictions best bets – Page 2

Chicago Bears at Indianapolis Colts odds, picks and predictions

Analyzing Saturday’s Chicago Bears at Indianapolis Colts odds and lines, with expert NFL picks and predictions.

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The Chicago Bears (1-0) battle the Indianapolis Colts (0-1) on Saturday in a Week 2 preseason game. Kickoff from Lucas Oil Stadium is scheduled for 7 p.m. ET (NFL Network). Below, we analyze BetMGM Sportsbook’s lines around the Bears vs. Colts odds, and make our expert NFL picks and predictions.

The Bears beat the Titans 23-17 to open their preseason. First-string QB Justin Fields saw limited action, but made the most of it going 3-for-3 for 129 yards and 2 TDs. Each TD was a dump pass, one to WR DJ Moore who took it 63 yards to the house and the other to RB Khalil Herbert, who took it 56 yards for the score.

The Colts fell 23-19 to the Buffalo Bills on Saturday in their opener with 1st- round draft pick QB Anthony Richardson struggling. He went 7-of-12 for 67 yards and an INT. Despite that, this week the Colts named Richardson as their regular-season starter. Indianapolis rushed for 2 TDs in the loss.

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Bears at Colts odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 11:18 a.m. ET.

Moneyline (ML): Bears +165 (bet $100 to win $165) | Colts -200 (bet $200 to win $100)
Against the spread (ATS): Bears +4.5 (-110) | Colts -4.5 (-110)
Over/Under (O/U): 38.5 (O: -110 | U: -110)

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Bears at Colts picks and predictions

Prediction

Colts 24, Bears 20

Moneyline

PASS.

With Fields and other starters sitting out against the Colts, there will not be a lot of weapons for Chicago to put together a winning performance. Richardson and the Colts will be looking for a bounce-back win in their 1st home game. Both backup QBs for Indianapolis, Gardner Minshew and Sam Ehlinger, performed well in Week 1 and should perform similarly against the Bears.

Against the spread

LEAN BEARS +4.5 (-110).

While the Colts are expected to win in this matchup, it is still preseason and with many moving pieces and new roles still being determined, it opens up the possibility of mistakes. And 4.5 points is too many to be confident for a Colts team that showcased many mistakes in their previous performance. While I would probably stay away from preseason spreads, if you need to put a wager down, lean Chicago to keep it within reach.

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Over/Under

BET OVER 38.5 (-110).

Both teams surpassed the 38.5 total points in their Week 1 outings and both teams have shown an ability to find the end zone. With Richardson looking to cement his claim as starter and show Indianapolis fans what they have to look forward to and with Chicago trying to replicate more explosive plays, expect points in this matchup.

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Indianapolis Colts at Buffalo Bills odds, picks and predictions

Analyzing Saturday’s Indianapolis Colts at Buffalo Bills odds and lines, with expert NFL picks and predictions.

The Indianapolis Colts face off against the Buffalo Bills Saturday in each team’s first preseason game. Kickoff from Highmark Stadium is set for 1 p.m. ET. Below, we analyze BetMGM Sportsbook’s lines around the Colts vs. Bills odds, and make our expert NFL picks and predictions.

The Colts finished last season with a dismal 4-12-1 overall record and they chased offensive talent and selected QB Anthony Richardson out of Flordia with the No. 4 overall pick in the 2023 draft. Indianapolis made other moves to increase their offensive firepower signing WR Isaiah McKenzie and RB Kenyan Drake.

There are still looming concerns around RB Jonathan Taylor heading into the 2023 campaign as the star running back remains on the PUP (physically unable to perform) list.

The Bills closed out the season with a 13-3 record and winning the AFC East, ultimately falling to the Cincinnati Bengals in the divisional round of the playoffs. Buffalo selected TE Dalton Kincaid out of Utah with the 25th pick in the draft, adding another weapon for QB Josh Allen.

Other notable offseason moves include defensive coordinator Leslie Frazier announcing he will be taking the year off, shocking players such as LB Von Miller, and leaving plenty of questions about how the defense will look in 2023. The Bills also re-signed DE Shaq Lawson to a one-year contract and signed S Taylor Rapp to a one-year contract.

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Colts at Bills odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 2:43 p.m. ET,

Moneyline (ML): Colts -185 (bet $185 to win $100) | Bills +150 (bet $100 to win $150)
Against the spread (ATS): Colts -3.5 (-110) | Bills +3.5 (-110)
Over/Under (O/U): 38 (O: -110 | U: -110)

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Colts at Bills picks and predictions

Prediction

Colts 24, Bills 20

Moneyline

BET COLTS (-185).

Bills coach Sean McDermott has already stated that Allen and WR Stefon Diggs will not play which is an indication we may not see many of the typical starters for Buffalo. However, on the defensive side of the ball, we may see S Damar Hamlin get some reps in what would be his first action since he went into cardiac arrest in early January.

Colts coach Shane Steichen has stated that Richardson will get the start. Expect to see Colts players playing deeper into the game than the Bills which should give them the edge.

Against the spread

PASS.

With many moving parts in Week 1 of the preseason, it will be difficult to have confidence in either side in this matchup. There is too much uncertainty for both sides, which is typical at this stage of the season. I recommend staying away from the spread.

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Over/Under

LEAN OVER 38 (-110).

With an ongoing battle between Richardson and QB Gardner Minshew, expect to see both QBs treat the game with an elevated seriousness. On the flip side, the Bills will be looking to use Week 1 of the preseason as a time to iron out kinks in their defense without a defensive coordinator.

For the Bills’ offense, while Allen will not see the field, backup QBs Kyle Allen and Matt Barkley certainly have the ability to hit receivers and find the end zone. That said, 38 points will require both offenses to find the end zone multiple times which is why sprinkling may be the best option.

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Houston Texans at Indianapolis Colts odds, picks and predictions

Analyzing Sunday’s Houston Texans at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

The Houston Texans (2-13-1) close out the season on the road Sunday against the Indianapolis Colts (4-11-1). Kickoff is at 1 p.m. ET at Lucas Oil Stadium (CBS). Below, we analyze Tipico Sportsbook’s lines around the Texans vs. Colts odds, and make our expert NFL picks and predictions.

The Texans are coming off a 31-3 drubbing in Week 17 at home against the Jacksonville Jaguars. They are a loss away from securing the No. 1 pick in the 2023 NFL Draft. They have lost 10 of their last 11 games.

The Colts have lost 6 straight games and are 1-6 since Jeff Saturdaywas named as interim coach. They are coming off a 38-10 loss to the New York Giants on the road as 5.5-point underdogs.

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Texans at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:47 a.m. ET.

Moneyline (ML): Texans +125 (bet $100 to win $125) | Colts -145 (bet $145 to win $100)
Against the spread (ATS): Texans +2.5 (-102) | Colts -2.5 (-118)
Over/Under (O/U): 37.5 (O: -112 | U: -108)

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Texans at Colts key injuries

Texans

WR Phillip Dorsett (hamstring) out
TE O.J. Howard (hip) questionable
OL Jimmy Morrisey (concussion) out
DB Steven Nelson (illness) questionable
DL Ogbonnia Okoronkwo (illness) questionable

Colts

CB Brandon Facyson (concussion) questionable
QB Nick Foles (ribs) out
CB Stephon Gilmore (wrist) questionable
TE Kylen Granson (ankle) out

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Texans at Colts picks and predictions

Prediction

Colts 20, Texans 16

Moneyline

This game is going to be hard to watch. The Texans need a loss to secure the No. 1 pick in the draft. If they win and the Chicago Bears lose, they would fall to No. 2. The Colts currently have the 5th pick.

The Colts and Texans have 2 of the 3 worst offenses in the league and both are among the worst defenses as well. The 2 teams tied 20-20 in Week 1.

This is a game I normally would stay far from. There is little incentive for either team to win. That said, I give the Colts the edge as the home team.

BET COLTS (-145).

Against the spread

The Texans are 7-8-1 ATS this season and the Colts are 6-10 ATS. Houston has covered the spread in 3 of the last 4 games while the Colts have failed to cover the spread in 4 of their last 5 games.

However, in a season finale, this is going to feel like a preseason game.

PASS.

Over/Under

The Texans have failed to reach 20 points in 8 of their last 10 games. The Under is 5-0 in the Texans’ last 5 division games.

The Colts have also failed to reach 20 points in 8 of their last 10 games.

BET UNDER 37.5 (-108).

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Indianapolis Colts at New York Giants odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at New York Giants odds and lines, with expert NFL picks, predictions and best bets.

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The Indianapolis Colts (4-10-1) visit the New York Giants (8-6-1) Sunday in a game with major playoff implications for one team. Kickoff from MetLife Stadium is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook’s lines around the Colts vs. Giants odds, and make our expert NFL picks and predictions.

The Colts currently are on a 5-game losing streak and have been eliminated from playoff contention. The preseason favorite to win the AFC South has underperformed and have many questioning the future of this team. The Colts are in 3rd place in the division, only 2 games ahead of the Houston Texans (2-12-1), and won’t be as focused in winning this game as they are looking toward to the offseason and the draft.

The Giants can secure the 6th seed in the NFC by simply winning Sunday. They missed the opportunity to clinch a playoff spot last Saturday, falling at the Minnesota Vikings 27-24 on a game-ending 61-yard field goal, but they covered the spread as 4.5-point underdogs. New York is 3rd in the NFC East behind the Philadelphia Eagles (13-2) and Dallas Cowboys (12-4), who have both clinched playoff berths.

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Colts at Giants odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 8:53 p.m. ET.

Moneyline (ML): Colts +200 (bet $100 to win $200) | Giants -240 (bet $240 to win $100)
Against the spread (ATS): Colts +5.5 (-110) | Giants -5.5 (-110)
Over/Under (O/U): 39 (O: -110 | U: -110)

Colts at Giants key injuries

Colts

TE Kylen Granson (ankle) out
CB Kenny Moore II (ankle) out
DL Yannick Ngakoue (throat) out — injured reserve
CB Isaiah Rodgers Sr. (knee) out — IR

Giants

CB Adoree’ Jackson (knee) doubtful
LB Azeez Ojulari (ankle) questionable

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Colts at Giants picks and predictions

Prediction

Giants 21, Colts 10

Moneyline

AVOID.

While the Giants (-240) should win this game, backing the -240 moneyline is not worth betting on. The Giants are the better team and have more to play for, which is why the moneyline is what it is, but to bet here would be bold. While I do agree with the line and think it could be even more lopsided, the risk here is not worth the reward.

Against the spread

LEAN GIANTS -5.5 (-110).

The Giants are simply much better than the Colts and I love the spread here. It’s big enough to show that the Giants are heavy favorites but is small enough to show that this will not be a blowout game.

The Giants are playing to clinch a spot in the playoffs and the Colts have nothing to play for as they have already been eliminated.

Expect the Giants to win by more than a touchdown.

Over/Under

BET UNDER 39 (-110).

These are two teams with very solid defenses and a lot of inconsistencies on the offensive side of the ball. UNDER 39 should be a safe bet.

Expect this to be a slow, defensive matchup that will not see a lot of scoring.

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Los Angeles Chargers at Indianapolis Colts odds, picks and predictions

Analyzing Monday’s Los Angeles Chargers at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

The Los Angeles Chargers (8-6) and the Indianapolis Colts (4-9-1) meet on Monday Night Football in Week 16. Kickoff from Lucas Oil Stadium is sct for 8:15 p.m. (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Chargers vs. Colts odds, and make our expert NFL picks and predictions.

The Chargers are alive and well in the AFC playoff picture after scoring big wins over the Miami Dolphins and Tennessee Titans in the last 2 weekends to strengthen their postseason chances.

The Colts are eliminated from the playoffs, and Indianapolis is coming off a historic 2nd-half collapse in Minnesota last week. The Colts were up 33-0 at half, but blew that lead and lost 39-36 in overtime.

It wasn’t QB Matt Ryan‘s fault the team struggled defensively in the second half last week, but interim coach Jeff Saturday is making the change to Nick Foles this week.

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Chargers at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 6:12 p.m. ET.

Moneyline (ML): Chargers -210 (bet $210 to win $100) | Colts +180 (bet $100 to win $180)
Against the spread: Chargers -4 (-112) | Colts +4 (-108)
Over/Under (O/U): 45.5 (O: -108 | U: -112)

Chargers at Colts key injuries

Chargers

CB Bryce Callahan (groin) questionable
S Derwin James Jr. (quadriceps) questionable
DL Sebastian Joseph-Day (knee, back) questionable
OT Trey Pipkins III (knee) questionable
LB Chris Rumph II (quadriceps) questionable

Colts

CB Brandon Facyson (illness) questionable
TE Kylen Granson (ankle) questionable
CB Kenny Moore II (ankle) questionable
WR Mike Strachan (concussion) questionable

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Chargers at Colts picks and predictions

Prediction

Chargers 29, Colts 16

Moneyline

The Chargers will cost you over 2 times your potential return, and that’s just a little too expensive, even against a struggling Colts team with nothing to play for.

AVOID, and look to the line instead.

Against the spread

Look to the CHARGERS -4 (-112) to cover on the road in this ultra-important game for them.

While L.A. is just 1-3-1 ATS in its last 5 games in December, including a 1-1-1 ATS mark this season, it is 5-2 ATS in the last 7 road games, and 5-2 ATS in the last 7 following a non-cover, too.

The Colts are likely emotionally checked out after yet another quarterback change, the huge collapse last week, and elimination from the playoffs.

Over/Under

UNDER 45.5 (-112) is the mostly dominant trend for both teams, and it is the lean, ever so slightly.

The Under is 5-2 in the last 7 games for the Chargers, while cashing at a 7-2 clip in the last 9 appearances on MNF.

While the Colts had a high-scoring game last Saturday in Minnesota, the Under is 6-2 in the last 8 games at home, while cashing in 6 of the last 8 against winning teams, too. The Under is also 4-0 in the last 4 at home against teams with a winning home record.

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Indianapolis Colts at Minnesota Vikings odds, picks and predictions

Analyzing Saturday’s Indianapolis Colts at Minnesota Vikings odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts (4-8-1) hit the road to play the Minnesota Vikings (10-3) Saturday in US Bank Stadium at 1 p.m. ET (NFL Network). Below, we analyze Tipico Sportsbook‘s lines around the Colts at Vikings odds, and make our expert NFL picks and predictions.

The Colts have lost 6 of their last 7 games and have scored fewer than 20 points in all 8 of their losses this season. Their only glimmer of hope is that the Vikings have the NFL’s worst-ranked pass defense.

The Vikings are coming off a 34-23 road loss as 2.5-point underdogs to the Detroit Lions, their 2nd loss in their last 4 games following a 7-game winning streak. Minnesota is allowing 24 points a game and in the last 5 games opponents are averaging more than 30 points a game.

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Colts at Vikings odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:22 p.m. ET.

Moneyline (ML): Colts +170 (bet $100 to win $170) | Vikings -200 (bet $200 to win $100)
Against the spread (ATS): Colts +4 (-109) | Vikings -4 (-111)
Over/Under (O/U): 47.5 (O: -100 | U: -110)

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Colts at Vikings key injuries

Colts

CB Brandon Facyson (illness) doubtful
CB Kenny Moore II (ankle) out

Vikings

C Garrett Bradbury (back) questionable
CB Cameron Dantzler (illness) questionable
OLB Danielle Hunter (neck) questionable
DL Harrison Phillips (back) questionable

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Colts at Vikings picks and predictions

Prediction

Vikings 27, Colts 20

Moneyline

PASS.

The Vikings need to get back on track and are 6-1 at home. That said, you should never place a bet where your return on investment is only half.

Against the spread

TAKE THE VIKINGS AND LAY 4 POINTS (-111).

The Vikings defense is brutal against the pass, but does a solid job against the run. They will be geared up to stop Jonathan Taylor and teams that do that beat the Colts consistently.

The Vikings are known for playing tight games, but only 3 of their wins have been by less than 4 points and all 3 of them were on the road. I’m projecting another 1-score win, but 1 that covers the required number of points.

Over/Under

TAKE THE UNDER 47.5 (-110).

It’s hard to imagine that any NFL team has scored more than 20 points just twice through 13 games. That is historically bad.

If they get held under 20 again, the Vikings would have push 30 or more points to hit the Over. If they get a lead, they will try to run the ball with Dalvin Cook and work the clock, making an Over/Under this high a lot more difficult to surpass.

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Indianapolis Colts at Dallas Cowboys odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Dallas Cowboys odds and lines, with expert NFL picks, predictions and best bets.

After 2 home games in a row, the Indianapolis Colts (4-7-1) are on the road in Week 13 to take on the Dallas Cowboys (8-3) Sunday night in prime time. The game at AT&T Stadium in Arlington kicks off at 8:20 p.m. ET (NBC). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Cowboys, and make our expert NFL picks and predictions.

The Colts won the coaching debut of Jeff Saturday 3 weeks ago with a 25-20 victory over the Las Vegas Raiders, but have dropped 2 straight games. They lost 24-17 to the Pittsburgh Steelers on Monday night as 2.5-point favorites after losing the week before 17-16 to the Philadelphia Eagles.

The Cowboys defeated the New York Giants 28-20 on Thanksgiving Day, but failed to cover the 10.5-point spread as favorites. They have a 2-game winning streak and have won 4 of their last 5 games.

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Colts at Cowboys odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:23 a.m. ET.

Moneyline (ML): Colts +400 (bet $100 to win $400) | Cowboys -500 (bet $500 to win $100)
Against the spread (ATS): Colts +10.5 (-113) | Cowboys -10.5 (-107)
Over/Under (O/U): 44 (O: -109 | U: -111)

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Colts at Cowboys key injuries

Colts

CB Kenny Moore II (ankle) out
CB Isaiah Rodgers (knee) questionable
OL Braden Smith (illness) out
TE Jelani Woods (shoulder, quad) questionable

Cowboys

LB Anthony Barr (hamstring) questionable
DT Quinton Bohanna (knee) questionable
CB Trevon Diggs (illness) questionable
WR Michael Gallup (illness) questionable
S Jayron Kearse (shoulder) questionable

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Colts at Cowboys picks and predictions

Prediction

Cowboys 27, Colts 13

Moneyline

The Cowboys are 5-1 at home this season and have won their last 5.

The Colts are 2-4 on the road, but their last win was on the road.

This is a game the Cowboys should win, even with potentially missing players with the flu bug. But with the moneyline what it is, PASS.

Against the spread

The Colts have lost by double digits only twice this season while the Cowboys have 5 double-digit wins out of their 8 this season.

The Colts have the most turnovers in the league (21) and the Cowboys are 8th in the league with 16 takeaways.

The Colts, averaging 15.8 points per game, are 20th in scoring. The Cowboys are No. 2 in points allowed at 17.0.

It appears unlikely the Colts will be able to even reach their season average, while the Cowboys have scored 28 or more in 4 straight games.

BET COWBOYS -10.5 (-113).

Over/Under

Only 3 of the Colts’ 12 games have seen the Over hit. The Cowboys are 4-6-1 O/U on the season.

Only 1 of the Colts’ last 6 games has had more than 44 total points.

BET UNDER 44 (-111).

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Pittsburgh Steelers at Indianapolis Colts odds, picks and predictions

Analyzing Monday’s Pittsburgh Steelers at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

The Pittsburgh Steelers (3-7) meet the Indianapolis Colts (4-6-1) for Monday Night Football in Week 12. Kickoff is scheduled for 8:15 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Steelers vs. Colts odds, and make our expert NFL picks and predictions.

The good news is that the Steelers posted a season-high 30 points last week at home against the Cincinnati Bengals. The bad news is that the Steelers allowed 37 points, the second-most they’ve surrendered this season.

Pittsburgh is just 1-3 in its last 4 games, although it is 3-2 against the spread (ATS) across the past 5, and the Under is 4-2 in the past 6 games.

The Colts are coming off a 17-16 loss last week at the Philadelphia Eagles, but coach Jeff Saturday’s team played well and covered as 6.5-point underdogs. Indianapolis 1-1 straight up (SU) and 2-0 ATS since the former Colts center and more recently, former ESPN analyst Saturday took the reins.

Indy is 2-3 at home, but 3-2 ATS there. Looking at totals, the Under is 9-2 in Colts games this season, including 4-1 in the past 5.

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Steelers at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 4:18 p.m. ET.

Moneyline (ML): Steelers +125 (bet $100 to win $125) | Colts -145 (bet $145 to win $100)
Against the spread: Steelers +2.5 (-104) | Colts -2.5 (-116)
Over/Under (O/U): 39 (O: -112 | U: -108)

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Steelers at Colts key injuries

Steelers

LB Robert Spillane (back) questionable
RB Jaylen Warren (hamstring) out
CB Ahkello Witherspoon (hamstring) out

Colts

DL DeForest Buckner (ribs, illness) questionable
LB Zaire Franklin (illness) questionable
TE Kylen Granson (illness) doubtful
DE Yannick Ngakoue (back) questionable
DE Kwity Paye (ankle) out

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Steelers at Colts picks and predictions

Prediction

Colts 20, Steelers 18

Moneyline

INDIANAPOLIS (-145) is a strong play, especially if you don’t want to mess around with laying the points with the spread as this should be a close, low-scoring game.

Three of the Colts’ past 4 games were one-possession games. For the season, 8 of their 11 games were decided by one score, including 2 overtime contests. Win or lose, Indy games are close.

As for Pittsburgh, while the season hasn’t been up to the lofty standards of the Steelers, 3 of their past 5 games have been one-possession finals — as have 6 of their 10 overall.

Against the spread

PASS.

If you like the Colts -2.5 (-116), just play them on the money line at -145 juice. It isn’t that big of a difference, and I expect this game to come right down to the end, perhaps due to a missed 2-point conversion, etc. … It will be that close.

Over/Under

UNDER 39 (-108) is the slight lean in this prime-time matchup.

The Steelers offense has really struggled this season, and their best quality is running the football. The Colts defense is solid against the run, allowing just 113.5 rushing yards per game. Overall, the Indy defense ranks 4th in the NFL with only 307.6 total yards allowed, including 194.2 passing yards per game to rank 6th.

While the Colts have run the ball well lately with a healthy RB Jonathan Taylor, stopping the run is what the Steelers defense does best. Pittsburgh yields just 103.4 rushing yards per game to rank 7th in the NFL.

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Philadelphia Eagles at Indianapolis Colts odds, picks and predictions

Analyzing Sunday’s Philadelphia Eagles at Indianapolis Colts odds and lines, with expert NFL picks, predictions and best bets.

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The Philadelphia Eagles (8-1) visit the Indianapolis Colts (4-5-1) Sunday at 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook’s lines around the Eagles vs. Colts odds, and make our expert NFL picks and predictions.

Coming off its first loss of the season — a 32-21 setback at Washington Monday night — Philadelphia travels to Indianapolis to battle the struggling Colts under new coach Jeff Saturday.

The Eagles, who were 11-point favorites, uncharacteristically had 4 turnovers against the Commanders. After having only 3 turnovers in its first 8 games, Philadelphia will look to return to the solid play which led them to the best start in the NFL through Week 9.

The Colts, after going away from QB Matt Ryan under coach Frank Reich, went back to the veteran last week against the Raiders and won 25-20. Ryan responded with 222 passing yards, 38 rushing yards and 2 TDs (1 passing, 1 rushing), including a career-best 39-yard TD for the Colts, who were 4.5-point road underdogs in Sin City.

They’ll look to continue their trek back into relevance at home this week. If they hope to pull off a second victory in a row, RB Jonathan Taylor will have to be a major part in the success. Against an Eagles defense which has strengthened itself in recent days against the run, it will be a difficult task.

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Eagles at Colts odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 9:31 p.m. ET.

Moneyline (ML): Eagles -290 (bet $290 to win $100) | Colts +240 (bet $100 to win $240)
Against the spread (ATS): Eagles -6.5 (-112) | Colts +6.5 (-108)
Over/Under (O/U): 45.5 (O: -110 | U: -110)

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Eagles at Colts key injuries

Eagles

TE Dallas Goedert (shoulder) out — injured reserve
CB Avonte Maddox (hamstring) out — IR

Colts

LB Zaire Franklin (illness) questionable
LB Shaquille Leonard (back) out — IR
DE Kwity Paye (ankle) out
CB Isaiah Rodgers (illness) questionable
OL Braden Smith (back) questionable

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Eagles at Colts picks and predictions

Prediction

Eagles 31, Colts 17

Moneyline

PASS.

The Eagles (-290) will look to rebound after their 1st loss in style. This does not bode well for the Colts. However, Philly’s price is too high to wager on.

Against the spread

BET EAGLES -6.5 (-112).

The Eagles are 4-0 on the road this season. They do not turn the ball over much — with only 7 on the season — which leads to being able to play from the lead. This is especially important in a road environment.

Although the Colts played hard for coach Saturday in his debut, it was against a Raiders team full of turmoil. The Eagles are not in turmoil and they will want to win this game to stay ahead of the Giants (7-2) and Cowboys (6-3) in the NFC East Division.

Although coming off a loss, I don’t see Philadelphia allowing Indy to keep this game close. The Eagles will want to make this an emphatic victory and jump out early. This should be a double-digit win for the Eagles, which is why PHILADELPHIA -6.5 (-112) is my FAVORITE PLAY in this game.

Over/Under

BET OVER 45.5 (-110).

The Colts have played 8 of their 10 games Under this season. One of those 2 Overs came last week against the Raiders in the 25-20 victory with an O/U line of 41.5. The other Over was a 34-27 home win against the Jaguars, also with an O/U of 41.5. With Taylor getting healthy and back on track, Ryan should be able to put up points in this game for the Colts.

After only scoring 21 points in the Monday home loss to the Commanders, the Eagles will look to get their offense back on track as well. Goedert is out and on IR, but WRs DeVonta Smith and A.J. Brown will provide plenty for QB Jalen Hurts to throw to. In the run game, after 0 TDs in 2021, RB Miles Sanders has 6 this season. He could add another rushing score Sunday as both teams will score some points. Although it could be a narrow escape, I like OVER 45.5 (-110) in this one.

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Indianapolis Colts at Las Vegas Raiders odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Las Vegas Raiders odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts (3-5-1) are on the road in Week 10 to face the Las Vegas Raiders (2-6). Kickoff is Sunday at 4:05 p.m. ET at Allegiant Stadium in Las Vegas (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Raiders odds and make our expert NFL picks and predictions.

The Colts fired Frank Reich as coach and named Jeff Saturday as interim coach, despite his having no coaching experience in the NFL. The Colts have lost 3 games in a row and are coming off a 26-3 loss to the New England Patriots last week.

The Raiders have lost 2 game in a row, blowing a 17-0 lead over the Jacksonville Jaguars in a 27-20 loss last week.

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Colts at Raiders odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:47 a.m. ET.

Moneyline (ML): Colts +170 (bet $100 to win $170) | Raiders -200 (bet $200 to win $100)
Against the spread (ATS): Colts +4.5 (-112) | Raiders -4.5 (-108)
Over/Under (O/U): 41 (O: -108 | U: -112)

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Colts at Raiders key injuries

Colts

RB Deon Jackson (knee) out
LB Shaquille Leonard (back, ankle) out
DE Kwity Paye (ankle) questionable
TE Jelani Woods (shoulder) out

Raiders

LB Denzel Perryman (hip, ribs) questionable

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Colts at Raiders picks and predictions

Prediction

Raiders 24, Colts 20

Moneyline

The Colts have not scored more than 16 points in the last 3 games and, outside of a 34-27 win over the Jaguars, have averaged only 14 points per game.

The Raiders have scored 20 or more in 6 of their last 7 games. However, they have allowed 20 or more points in every game this season.

The anemic Colts offense might threaten, but the Raiders should hold on.

That said, it isn’t worth betting the moneyline here. PASS.

Against the spread

The Colts have not covered the spread in 3 straight games and the Raiders have failed to do so in their last 2.

The question is whether the Colts can score more than they have against a Las Vegas defense that has let everyone score.

Expect a new coach boost of play from the Colts to keep the game close.

BET COLTS +4.5 (-112).

Over/Under

All but 1 of the Raiders’ games this season have had totals of more than 40.

Only 1 of the Colts’ games has passed 41 points.

As noted, the Raiders have allowed at least 20 points in every game this season.

Bet OVER 41 (-108).

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