Week 1 best bets: NFL picks and predictions for Sunday’s games

Looking at the best bets for the NFL’s Week 1 Sunday slate, with money line, ATS and Over/Under picks and predictions.

The first Sunday of the 2021 NFL season is here. SportsbookWire.com runs through the opening slate, with NFL picks, predictions and best bets against the money line, spread and Over/Under. Check out our staff picks and predictions before locking in your Week 1 bets.

The Dallas Cowboys and Tampa Buccaneers got the season underway Thursday night. The Buccaneers won 31-29 but the Cowboys covered as 8.5-point underdogs and the game sailed Over the projected total of 51.5 points.

Also see: NFL team win totals, playoff lines and Super Bowl odds

Odds provided by Tipico Sportsbook.

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Miami Dolphins at New England Patriots odds, picks and prediction

Analyzing the Week 1 Miami Dolphins at New England Patriots odds and lines, with expert NFL picks, predictions and best bets.

The Miami Dolphins visit Gillette Stadium Sunday to tangle with the New England Patriots in their regular-season opener. Kickoff is scheduled for 4:25 p.m. ET. Below, we look at the Dolphins vs. Patriots odds and lines, and make our best NFL picks, predictions and bets.

Miami improved by five wins from 2019 to 2020 with a 10-6 record in head coach Brian Flores’ second season and tied the Buffalo Bills with the highest regular-season cover rate at 11-5 against the spread.

New England finished just 7-9  last season and wound up selecting QB Mac Jones with the 15th overall pick in the 2021 NFL Draft. The 2020 season was the Patriots’ first sub-.500 campaign since head coach Bill Belichick’s first year on the job in 2000.

The reasons are obvious: It was the first season in the post-Tom Brady era and the Patriots had more than double the next-most adjusted games lost due to COVID-19 last year, according to Football Outsiders.

Also see: NFL team win totals

Dolphins at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 1:15 p.m. ET.

  • Money line: Dolphins +160 (bet $100 to win $160) | Patriots -200 (bet $200 to win $100)
  • Against the spread (ATS): Dolphins +3.5 (-108) | Patriots -3.5 (-105)
  • Over/Under (O/U): 43.5 (O: -110 | U: -110)

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Dolphins at Patriots key injuries

Dolphins

  • WR Will Fuller (suspended) out
  • WR Preston Williams (foot) questionable

Patriots

  • WR Nelson Algholor (ankle) questionable
  • CB Jalen Mills (ankle) questionable
  • CB Stephon Gilmore (quadriceps) out

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Dolphins at Patriots odds, lines, predictions and picks

Prediction

Dolphins 23, Patriots 20

Money line

Slight “LEAN” to the DOLPHINS (+160) for a quarter unit, if at all, because Miami plus the points is a wiser wager but there’s enough value with the underdog to sprinkle some change on the money line.

This game opened with New England laying just -125 on the money line before the Patriots were dropped 75 cents on the dollar.

Essentially, my idea is to fade that line movement because it’s due to New England making Jones the starting quarterback against one of the best defensive head coaches in the league.

New England’s price is increasing because the media is chirping about the more popular team. There’s no way the Patriots should be this heavy of a favorite starting a rookie in Week 1 with mediocre receivers.

Also see: Week 1 staff picks

Against the spread

Definitely BET the DOLPHINS +3.5 (-108) heavier than or instead of Miami’s money line as a fade against a lopsided betting market that has pushed this line past the key number of 3.

Furthermore, over the past five seasons, road underdogs are 14-7-1 ATS against divisional foes in Week 1. Miami is also tied for the second-best cover rate in division games (8-4 ATS) since hiring Flores.

Lastly, I’m higher than the market on Dolphins QB Tua Tagovailoa and Miami’s offense in his second season.

Tua came into his rookie season rehabbing a dislocated hip injury he suffered in college, didn’t get the benefit of a normal offseason due to the COVID pandemic and played in an offense built for former Miami QB Ryan Fitzpatrick. Oh, and the Dolphins wide receiver room had the most adjusted games lost due to injury last season.

Over/Under

Dolphins-Patriots has all the makings of a low-scoring game with two young quarterbacks going against defensive wizards at head coach.

However, the market feels the same way and has hammered the Under so much so that sportsbooks have moved the total down from the 46.5-point opener to the listed number.

I hate following a crowd in sports betting and we are getting the worst of the number. PASS ON THE TOTAL.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

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Denver Broncos at New York Giants odds, picks and prediction

Analyzing the Week 1 Denver Broncos at New York Giants odds and lines, with expert NFL picks, predictions and best bets.

The Denver Broncos and New York Giants meet Sunday at MetLife Stadium. Kickoff is scheduled for 4:25 p.m. ET and the game is televised on FOX. Below, we look at the Broncos vs. Giants odds and lines, and make our best NFL picks, predictions and bets.

The Broncos head to the Eastern Time Zone where they had a ton of success a season ago. Denver went 3-2 straight up and 4-1 against the spread in five trips east of the Mississippi River, while going 2-9 SU and 5-6 ATS elsewhere.

The Giants had a difficult time against AFC teams last season, going just 1-3 SU and 0-4 ATS. New York also hit the Under in all four games against AFC opponents in 2020. The G-Men are just 3-9 ATS over the last three seasons against AFC foes.

Also see: NFL team win totals

Broncos at Giants odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 12:50.m. ET.

  • Money line: Broncos -160 (bet $160 to win $100) | Giants +130 (bet $100 to win $130)
  • Against the spread (ATS): Broncos -2.5 (-135) | Giants +2.5 (+110)
  • Over/Under (O/U): 41.5 (O: -108 | U: -112)

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Broncos at Giants key injuries

Broncos

  • LB Bradley Chubb (ankle) questionable

Giants

  • RB Saquon Barkley (knee) questionable
  • TE Evan Engram (calf) out
  • DB Adoree’ Jackson (ankle) questionable

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Broncos at Giants odds, lines, predictions and picks

Prediction

Broncos 26, Giants 17

Money line

The BRONCOS (-160) are moderate favorites, and not a bad option on the money line if you just want to pick a winner and not worry about the point spread.

The Giants haven’t had a lot of success against the AFC in recent seasons, and the fact Barkley is dinged up and Engram is out does not help matters. New York could get off to a slow start yet again.

Also see: Week 1 staff picks

Against the spread

BRONCOS -2.5 (-135) is worth a small-unit play, as Denver seemed to enjoy traveling last season. Most of their best games were away from home.

QB Teddy Bridgewater makes his team debut and has a solid stable of receivers. The Giants aren’t nearly as deep. Engram would’ve been super helpful for QB Daniel Jones, but he is already ruled out. That’s bad news for the home side, and it gets worse if Barkley is ruled inactive.

Over/Under

The lean is to the OVER 41.5 (-108), ever so slightly.

The concern is with the Giants side, again, if Barkley cannot play. Bridgewater and the Broncos offense should be much better than last season, and they should do enough to inch this one Over the finish line for total bettors.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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New York Jets at Carolina Panthers odds, picks and prediction

Analyzing the New York Jets at Carolina Panthers Week 1 odds and lines, with expert NFL picks, predictions and best bets.

The New York Jets and Carolina Panthers meet Sunday at Bank of America Stadium in Charlotte. Kickoff is scheduled for 1 p.m. ET and the game is televised on CBS. Below, we look at the Jets vs. Panthers odds and lines, and make our best NFL picks, predictions and bets.

The Jets traded QB Sam Darnold to the Panthers and then selected QB Zach Wilson out of BYU with the No. 2 overall pick in the 2021 NFL Draft. As luck has it, these two players and teams face each other in Week 1.

Wilson looked very good in the preseason, but he’ll be without one of his top receivers with WR Jamison Crowder on the COVID-19 list and ruled out by head coach Robert Saleh.

Darnold looks to exact a little revenge on the team which gave up on him, and show the Jets what they could’ve been if they had NFL-caliber receivers and a top-notch running back. That’s what he has in Charlotte with the Panthers.

Also see: NFL team win totals

Jets at Panthers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 12:30 p.m. ET.

  • Money line: Jets +170 (bet $100 to win $170) | Panthers -210 (bet $210 to win $100)
  • Against the spread (ATS): Jets +4.5 (-115) | Panthers -4.5 (-107)
  • Over/Under (O/U): 45.5 (O: -105 | U: -115)

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Jets at Panthers key injuries

Jets

  • WR Keelan Cole (knee) questionable
  • WR Jamison Crowder (COVID-19) out
  • RB La’Mical Perine (foot) questionable
  • Sharrod Neasman (hamstring) out

Panthers

  • No notable injuries

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Jets at Panthers odds, lines, predictions and picks

Prediction

Panthers 27, Jets 20

Money line

The new-look Panthers (-210) will cost you more than two times your potential return against the Jets. Carolina enters the game healthier than its counterparts, but it’s still a risky play at this price.

The Panthers lost their last two regular-season openers, both at home, and they failed to cover in each while the Over connected.

AVOID and look to the spread.

Also see: Week 1 staff picks

Against the spread

While the Jets might have a lot of the focus on them in this matchup because of their shiny new quarterback, this is a redemption story and the PANTHERS -4.5 (-107) are beginning a new era.

Darnold looks to keep his old organization down, and he’ll do just that with former Jets WR Robby Anderson, WR DJ Moore and RB Christian McCaffrey helping him out.

The Jets went 1-4 ATS in their last five regular-season openers, and they’re 1-8 ATS in their last nine September games.

Over/Under

The OVER 45.5 (-105) is worth a small-unit play. Darnold and Wilson will be locked in a battle here, and it has the chance to be a very exciting game.

The Over cashed in each of the last two regular-season openers for the Panthers, and we should see a third straight with a game in the upper 40s. Be patient, though, as things could get off to a slow start before the quarterbacks get their sea legs.

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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Prop Bet Payday: Week 1 player picks and predictions

Analyzing the NFL’s Week 1 slate with picks and predictions for the top 5 player props.

It’s Week 1 and every team enters the season with a clean slate and dreams of playing in the Super Bowl (except Houston and Detroit). Every team has turned over its roster in hopes of finding the right combination to be a playoff contender. Below, we look at top 5 NFL player props for Week 1; visit SportsbookWire.com for all of our game breakdowns.

These are five players we think have prop bet numbers that can help bring you to the Week 1 pay window – some because they aren’t given the respect they deserve and others because the numbers are too daunting to meet.

Also see: 2021 NFL team win totals

Week 1 Prop Bet Payday picks and predictions

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 12:10 p.m. ET.

Vikings RB Dalvin Cook OVER 99.5 rushing yards (-114)

In four career Week 1 games, Cook topped 110 yards twice – both when playing non-division opponents (New Orleans and Atlanta). Minnesota’s offensive line has had its share of struggles the last few years, but Cook has found a way to be a dominant back despite the problems.

The 97.5 yards is a big number that might scare off a lot of bettors, but the Bengals had the 31st ranked run defense last season by yards per attempt and despite making some high-profile signings in the offseason, stopping the run is going to remain an issue for this defense. Cook’s history of starting strong continues here.

Take the OVER 99.5 (-114).

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Also see: Vikings vs. Bengals odds, picks and predictions

Seahawks WR DK Metcalf OVER 77.5 receiving yards (-130)

The Colts had the league’s second best run defense in 2020, which often forced opponents to give up on trying to pound the ball, so teams often threw much more often than they ran.

Seattle isn’t afraid to pass early and often and Metcalf is becoming one of the most dominant receivers in the game. The Colts cornerbacks are pedestrian when healthy and Xavier Rhodes is out this week. QB Russell Wilson could have a big day attacking this weakness and nobody makes mismatches like Metcalf.

Take the OVER 77.5 (-130).

Also see: Seahawks vs. Colts odds, picks and predictions

Bills QB Josh Allen UNDER 280.5 passing yards (-114)

The Steelers have a very good defense and, while they’re a significant underdog, it’s not because their defense can’t get the job done. They had the No. 2 defense in the league by yards per play despite a late-season collapse (again not the fault of the defense).

Allen is being viewed as an MVP frontrunner but during his breakout 2020 season, he played Pittsburgh at home and threw 43 times for just 238 yards. Allen had five games with 238 or fewer yards – all at home. Wait until he’s on the road to see the huge numbers.

Take the UNDER 280.5 (-114).

Also see: Steelers vs. Bills odds, picks and predictions

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Browns RB Kareem Hunt OVER 34.5 rushing yards (-114)

Sometimes when it comes to taking a yardage prop bet, you look at intangibles you don’t find on a stat sheet. Hunt led the NFL in rushing in 2017 as a member of the Kansas City Chief. Sunday will be his first career game against his former team.

The Browns are one of the most dominant run teams in the league and they like to mix-and-match Nick Chubb and Hunt. Chubb will likely get twice the number of carries, but revenge is a thing in the NFL and head coach Kevin Stefanski will likely give Hunt more chances than normal to make a statement to his former team.

Take the OVER 34.5 (-114).

Also see: Browns vs. Chiefs odds, picks and predictions

Falcons WR Calvin Ridley UNDER 87.5 receiving yards (-114)

Ridley has been an emerging star since he joined the league, but he always had the luxury of playing opposite Julio Jones, who typically commanded either the top cornerback or a safety sliding over to bracket him. Ridley was the No. 2 guy both in the offense and in the mind of the defense.

With Jones gone, opponents are going to give a lot more coverage to Ridley. The same has happened many times and too often the guy who thrived in single coverage has to adjust to the new attention he gets from defensive coordinators. It takes time, this is Week 1 and the Eagles won’t be shy about doubling him and making someone else do the damage.

Take the UNDER 87.5 (-114).

Also see: Eagles vs. Falcons odds, picks and predictions

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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Philadelphia Eagles at Atlanta Falcons odds, picks and prediction

Analyzing the Philadelphia Eagles at Atlanta Falcons Week 1 odds and lines, with expert NFL picks, predictions and best bets.

The Atlanta Falcons play host to the Philadelphia Eagles at Mercedes-Benz Stadium Sunday of Week 1. Kickoff will be at 1 p.m. ET. Below, we look at the Eagles vs. Falcons odds and lines, and make our best NFL picks, predictions and bets.

It’s a new regime in Atlanta after head coach Dan Quinn was fired at the end of a disappointing 2020 campaign in which the Falcons went 4-12 and finished last in the NFC South. Former Tennessee Titans offensive coordinator Arthur Smith now leads the charge.

Philadelphia also made a head coaching change after going 4-11-1 and finishing last in the NFC East. Doug Pederson was replaced by former Indianapolis Colts offensive coordinator Nick Sirianni, who hopes to get the best out of second-year QB Jalen Hurts.

Also see: 2021 NFL team win totals

Eagles at Falcons odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 11:33 a.m. ET.

  • Money line: Eagles +155 (bet $100 to win $155) | Falcons -190 (bet $190 to win $100)
  • Against the spread (ATS): Eagles +3.5 (-112) | Falcons -3.5 (-108)
  • Over/Under (O/U): 48.5 (O: -112 | U: -108)

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Eagles at Falcons key injuries

Eagles

  • OL Landon Dickerson (knee) out
  • Rodney McLeod (knee) out
  • LB Davlon Taylor (calf) questionable

Falcons

  • None

Also see: Underdog Corner

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Eagles at Falcons odds, lines, predictions and picks

Prediction

Falcons 28, Eagles 23

Money line

The FALCONS (-190) are just inside the limits of a playable money line bet on home field. Give an edge to Smith in the battle of new head coaches, after he led the Titans to a fourth-ranked 30.7 points per game and fifth-ranked 6.2 yards per play last season.

Veteran RB Mike Davis was signed in the offseason to improve 2020’s woeful rushing attack and TE Kyle Pitts was selected fourth overall in the 2021 NFL Draft. Former MVP QB Matt Ryan has enough weapons to start the season with a win over Hurts and the younger Eagles offense.

Also see: Bet Slippin’ Podcast (jump to 33:37)

Against the spread

The better value is to back the FALCONS -3.5 (-108) to win by 4 or more points.

Though they registered just 29 sacks and a modest 12 interceptions last season, the Falcons were fourth in ESPN’s team pass rush win rate. Long-time defensive coordinator Dean Pees joins Smith in Atlanta and now leads a unit that underwent considerably less offseason change than in recent years.

The Eagles were just 11th in pass block win rate and QBs Hurts and Carson Wentz were pressured on 27.8% of all dropbacks.

Over/Under

OVER 48.5 (-108) is a strong play. Both teams brought in a former offensive coordinator to be head coach and also used their respective first-round picks on top-tier pass catchers.

Also see: Week 1 staff picks

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

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Cleveland Browns at Kansas City Chiefs odds, picks and prediction

Analyzing the Cleveland Browns at Kansas City Chiefs Week 1 odds and lines, with expert NFL picks, predictions and best bets.

The Cleveland Browns and Kansas City Chiefs meet Sunday at Arrowhead Stadium. Kickoff is scheduled for 4:25 p.m. ET and the game is televised on CBS. Below, we look at the Browns at Chiefs odds and lines, and make our best NFL picks, predictions and bets.

The Browns head into this regular-season opener looking to snap an ugly run. They’re 0-15-1 in Week 1 since 2005, and they’re 5-15-1 against the spread in their previous 21 Week 1 games.

The defending AFC champion Chiefs have no such bad luck in Week 1, or otherwise lately. They covered the spread in each of their past four regular-season openers, while going 12-2 ATS in their last 14 games in September.

Also see: 2021 NFL team win totals

Browns at Chiefs odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 11:55 a.m. ET.

  • Money line: Browns +190 (bet $100 to win $190) | Chiefs -240 (bet $240 to win $100)
  • Against the spread (ATS): Browns +5.5 (-110) | Chiefs -5.5 (-110)
  • Over/Under (O/U): 54.5 (O: -115 | U: -105)

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Browns at Chiefs key injuries

Browns

  • WR Odell Beckham Jr. (knee) questionable
  • DE Jadeveon Clowney (illness) questionable
  • Grant Delpit (hamstring) questionable
  • Ronnie Harrison Jr. (ankle) questionable
  • JC Tretter (knee) questionable
  • PK Chase McLaughlin (hamstring) questionable

Chiefs

  • DE Frank Clark (hamstring) questionable
  • DT Derrick Nnadi (hip) questionable
  • OL Austin Blythe (abdomen) out

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Browns at Chiefs odds, lines, predictions and picks

Prediction

Chiefs 34, Browns 24

Money line

The Chiefs (-240) will cost you two and a half times your potential return, and that’s a little too much risk despite the fact the Browns have been awful in regular-season openers for over a decade and a half.

AVOID and look to the spread.

Against the spread

CHIEFS -5.5 (-110) is a great play in the regular-season opener in this replay of last season’s AFC Divisional Round playoff game. The public has been all over the Browns, and it’s a bit misguided.

Perhaps some bettors are looking at last season’s 22-17 playoff game near-miss by the Browns in Kansas City, but remember, Chiefs QB Patrick Mahomes was knocked out of that game for a large chunk. Backup QB Chad Henne finished up and the Chiefs still won the game.

This one won’t be nearly as close.

Over/Under

The play is the OVER 54.5 (-115) in this AFC showdown between two Super Bowl hopefuls.

I like the fact the Over is 6-0 in the past six regular-season openers for the Chiefs while they’ve hit the Over in 15 of their last 21 September games, as well.

We have two top-notch quarterbacks and a bevy of impressive skill position players on both sides. The defenses won’t be able to keep up.

Also see: Week 1 staff picks

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

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Access more NFL coverage:

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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San Francisco 49ers at Detroit Lions odds, picks and prediction

Analyzing the San Francisco 49ers at Detroit Lions Week 1 odds and lines, with expert NFL picks, predictions and best bets.

The Detroit Lions host the San Francisco 49ers for their Week 1 regular season openers at Ford Field with kickoff scheduled for 1 p.m. ET. Below, we look at the 49ers at Lions odds and lines, and make our best NFL picks, predictions and bets.

San Francisco’s 2020 season was your standard “Super Bowl loser curse” as the 49ers finished 6-10 due in large part to a plethora of injuries to their starting lineup. San Francisco had by far the most adjusted games lost to injury, according to Football Outsiders.

Detroit moves into a new era after parting ways with head coach Matt Patricia and granting Matthew Stafford’s trade request by sending him to the Los Angeles Rams for QB Jared Goff and draft capital.

The Lions finished in the cellar of the NFC North with a 5-11 record and missed the playoffs for the fourth consecutive season.

49ers at Lions odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 11:16 a.m. ET.

  • Money line: 49ers -450 (bet $450 to win $100) | Lions +330 (bet $100 to win $330)
  • Against the spread (ATS): 49ers -8.5 (-112) | Lions +8.5 (-108)
  • Over/Under (O/U): 45.5 (O: -115 | U: -105)

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49ers at Lions key injuries

49ers

  • DT Javon Kinlaw (knee) doubtful
  • CB Emmanuel Moseley (knee) doubtful

Lions

  • LT Taylor Decker (finger) out
  • DE Michael Brockers (shoulder) questionable

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49ers at Lions odds, lines, predictions and picks

Prediction

49ers 24, Lions 20

Money line

PASS with a slight “lean” to the Lions (+330) because I love the value with their spread and, generally like to sprinkle on an underdog’s money line when taking them plus points.

Against the spread

Everyone and their grandmother is betting the 49ers -8.5, adding their money line as an odds booster to their parlay and teasing San Francisco down to a better number.

However, it’s typically profitable fading lopsided betting markets and heavy favorites in the NFL, especially early in the season. It’s rare that a road team is favored more than a touchdown in Week 1.

Road teams getting at least 7.5 points in Week 1 are 3-1 ATS since 2011, and the pricing makes the 49ers-Lions contest comparable to those games. Each contest pitted a preseason Super Bowl-favorite against a team expected to finish in the basement of the NFL standings. This spot is no different.

However, I have a hunch new Detroit head coach Dan Campbell will have his guys ready to play in Week 1. Campbell has a completely different vibe than Patricia and he’ll rally the Lions around the “nobody believes in us” narrative.

I’m skeptical San Francisco’s regains its defensive form from 2019 because the secondary is older and thinner and former defensive coordinator Robert Saleh was hired for head coaching vacancy with the New York Jets. Detroit’s offensive line has some talent and can keep Goff upright long enough for the Lions to have success on offense.

GIMME the LIONS +8.5 (-108) for 1 unit.

Over/Under

Slight “LEAN” to the UNDER 45.5 (-105) for a one-third unit since my predicted score isn’t that far off of Tipico’s listed total.

I’m expecting San Francisco to struggle a tad out of the gate offensively because it’ll need to knock the rust off since QB Jimmy Garoppolo and many of his weapons missed most of last year with injuries.

If 49ers-Lions is as one-sided as the market action then UNDER 45.5 (-105) could serve as a slight hedge for our Detroit wager if San Francisco dominates. The 49ers ranked 25th and 29th in pace over the past two seasons, according to Football Outsiders.

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WATCH: Philadelphia Eagles at Atlanta Falcons, Week 1, Key Facts, Stats

See betting lines, statistical trends and relevant facts for the 2021 NFL season opener between the Atlanta Falcons and Philadelphia Eagles.

The Atlanta Falcons host the Philadelphia Eagles Sunday to open their seasons. Six of the last seven times these two teams met, the underdog has walked away with a win.

The Eagles haven’t done too well on the road of late, having lost their last six Sunday road games. The Falcons, however, lost their last four games as home favorites against NFC opponents and lost their last five games as favorites in September. Both of these teams will look to turn it around in their 2021 season openers. Go to Tipico Sportsbook for the most updated odds.

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For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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WATCH: Jacksonville Jaguars at Houston Texans, Week 1, Key Facts, Stats

See betting lines, statistical trends and relevant facts for the 2021 NFL season opener between the Jacksonville Jaguars and Houston Texans.

The Houston Texans host the Jacksonville Jaguars in Week 1, where the Jaguars will look for their first win in 16 games. The Texans hold a six game win streak against the Jaguars, but have lost their last four season openers.

The Jags look to rookie QB Trevor Lawrence to make an immediate impact. Go to Tipico Sportsbook for the most updated odds.

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For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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