Chicago Cubs at San Francisco Giants odds, picks and predictions

Analyzing Thursday’s Chicago Cubs at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (37-44) and San Francisco Giants (39-42) finalize a 4-game set with a Thursday matinee. First pitch from Oracle Park is tabbed for 3:45 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 4-2

The Cubs are looking to avoid being swept in 4. Chicago has dropped the first 3 games of this series and is just 4-9 over its last 13 games.

San Francisco surged in late May but had been on the skids heading into this series. The Giants lost 5 straight June 18-23 and had been just 7-15 over their previous 22 games.

Cubs at Giants projected starters

LHP Shota Imanaga vs. RHP Jordan Hicks

Imanaga (7-2, 2.96 ERA) is making his 15th start. He has a 1.10 WHIP, 1.4 BB/9 and 9.2 K/9 in 79 IP.

  • Last outing: Loss, 3 IP, 10 ER, 11 H, 1 BB, 3 K in 11-1 home defeat vs. New York Mets Friday
  • Never faced Giants before
  • Allowed 3 home runs in his last start and has yielded 7 HR in his last 25 1/3 IP

Hicks (4-4, 3.24 ERA) makes his 17th start. He has a 1.28 WHIP, 3.5 BB/9 and 7.7 K/9 in 80 2/3 IP.

  • Last outing: Loss, 4 IP, 5 ER, 6 H, 3 BB, 1 K in 9-4 loss at St. Louis Cardinals Saturday
  • Career vs. Cubs: 2-1, 2.88 ERA (25 IP, 8 ER), 13 H, 15 BB, 23 K in 1 start and 18 relief appearances
  • Has held current Cubs batters to an aggregate .599 OPS per ESPN
  • Has been aided by a .261 batting average on balls in play with runners in scoring position

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cubs at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:39 a.m. ET.

  • Moneyline: Cubs -115 (bet $115 to win $100) | Giants -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+150) | Giants +1.5 (-185)
  • Over/Under (O/U): 7.5 (O: -110 | U: -110)

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Cubs at Giants picks and predictions

Prediction

Cubs 5, Giants 4

Moneyline

Imanaga’s last-game results were logged on the mound but also came out of left field. The Cubs southpaw toted a minuscule 1.89 ERA into that start. Imanaga did have one other clunker this season, and his bounceback was solid enough.

Hicks comes in with the lesser form of late, and his expected-ERA figures indicate more regression on the horizon.

In the big team picture, San Francisco looks to be a couple or 3 wins too far out over its skis. And the Giants are just 9-15 against lefty starters.

FanDuel Sportsbook has the budget line for the visitors in this one. BET THE CUBS (-108).

Run line/Against the spread

Chicago plays in a slew of 1-run games and has already played 4 such contests against this San Francisco club. PASS.

Over/Under

The last 7 Giants games have seen 5 Overs. And the Over has the leverage lean in this series finale.

Both starters have expected ERAs higher than their surface figures. The Chicago bullpen owns a 4.52 ERA and is so-so at best. The San Francisco relief corps is under a fatigue caution flag with the back-end work filed the last few days.

On an afternoon with an outward breeze in the forecast, BACK THE OVER 7.5 (-110).

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Chicago Cubs at San Francisco Giants odds, picks and predictions

Analyzing Wednesday’s Chicago Cubs at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (37-43) and San Francisco Giants (38-42) meet Wednesday for the 3rd game of a 4-game set. First pitch from Oracle Park is slated for 9:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 3-2

Chicago was outscored 10-5 in losing the 1st 2 games of this series, and the Cubs have lost 3 in a row overall. On the road, the Cubs are 4-14 since May 13.

San Francisco went into this series on a 5-game losing streak. The Giants are seeking a 3rd straight win, a would-be first for them since June 5-8.

Cubs at Giants projected starters

RHP Hayden Wesneski vs. RHP Hayden Birdsong

Wesneski (2-4, 3.29 ERA) is lined up for his 4th start and 21st appearance. He has a 1.20 WHIP, 3.3 BB/9 and 8.1 K/9 through 41 IP.

  • Last outing: No-decision, 2 relief IP, 1 ER, 2 H, 2 BB, 2 K in 11-1 home loss vs. New York Mets Friday
  • 2024 vs. Giants: 0-0, 18.00 ERA (1 IP, 2 ER), 1 H, 4 BB, 1 K in 1 relief appearance of 7-6 home loss June 17
  • Career vs. Giants: 0-2, 11.88 ERA (8 1/3 IP, 11 ER), 10 H, 7 BB, 8 K in 1 start and 3 relief appearances

Birdsong is a 22-year-old making his MLB debut.

  • Being promoted from Triple-A Sacramento after spending just 2 weeks there
  • 2024 stats with Triple-A Sacramento: 1-0, 5.00 ERA (9 IP, 5 ER), 1.56 WHIP, 14.0 K/9 in 2 starts
  • Owns a combined 2.51 ERA across 57 1/3 IP at Double- and Triple-A
  • Regarded as one of the Giants’ top pitching prospects

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cubs at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:49 p.m. ET.

  • Moneyline: Cubs +105 (bet $100 to win $105) | Giants -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-200) | Giants -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: -130 | U: -105)

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Cubs at Giants picks and predictions

Prediction

Cubs 4, Giants 3

Moneyline

Lots of pitching uncertainty clouds the picture for this one. Consider partial-unit betting all around with sides and totals.

Right-handers bring out the lesser side of San Francisco’s platoon splits (.678 OPS vs. right-handers). Control could be a weakness for Birdsong, and the CUBS (+105) own a robust 9.8% walk rate against righties.

The bullpens figure to loom large in this one. Chicago’s is better rested amongst the high-leverage arms. TAKE CHICAGO (+105).

Run line/Against the spread

A Cubs lean priced out of value range: AVOID.

Over/Under

The Under has prevailed in 7 of Chicago’s last 8 games away from Wrigley Field and 8 of the Cubs’ last 11 at San Francisco.

The Chicago bullpen is well-rested in the back end, and the Giants’ bullpen has put up better numbers at home.

Peg the UNDER 7.5 (-105) with a slight lean.

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Chicago Cubs at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s Chicago Cubs at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (37-42) and San Francisco Giants (37-42) meet Tuesday as they continue a 4-game series. First pitch from Oracle Park is slated for 9:45 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: tied 2-2

Chicago spit the bit on a mid-game 4-0 lead and lost Monday’s series opener 5-4. Two Cubs relievers were touched up for 3 runs in the bottom of the 9th as Chicago lost for the 3rd time in its last 4 games.

San Francisco snapped a 5-game losing streak with Monday’s walk-off victory. Giants pitching had logged a 6.21 ERA over its previous 7 games.

Cubs at Giants projected starters

RHP Kyle Hendricks vs. RHP Randy Rodriguez

Hendricks (1-4, 7.46 ERA) is making his 9th start and 14th appearance. He has a 1.58 WHIP, 2.8 BB/9 and 6.9 K/9 through 50 2/3 innings.

  • Last start: Win, 5 2/3 IP, 1 ER, 2 H, 1 BB, 8 K in 6-5 home win vs. Giants Wednesday — his only outing vs. San Francisco this season
  • Career vs. Giants (regular season): 7-2, 2.30 ERA (82 IP, 21 ER), 0.91 WHIP, 7.6 K/9 in 13 starts
  • Allowed just 1 run in 14 1/3 innings this month for a 0.63 ERA (4 outings, including 1 start)
  • Held current Giants batters to an aggregate .367 OPS, according to ESPN.com

Rodriguez (2-1, 4.82) is projected to make his 1st career start, which will likely be an “opener role.” The rookie has made 18 relief appearances since his MLB debut in early May. He has a 1.25 WHIP, a 2.9 BB/9 and a 10.0 K/9 in 28 innings. Rookie southpaws Erik Miller (2-2, 4.00 ERA, 1.22 WHIP) and LHP Carson Whisenhunt (2-3, 4.87 ERA, 1.57 WHIP at Triple-A) are possibilities to take the hill once Rodriguez is removed.

  • Rodriguez’s last outing: No-decision in relief appearance, 1 IP, 0 ER, 0 H, 0 BB, 1 K in 5-3 loss at St. Louis Cardinals Sunday
  • Career vs. Cubs: 1 outing, 1 blown save, 1 2/3 IP, 3 ER, 4 H, 1 HR, 0 BB, 0 K in 7-6 win at Wrigley June 17
  • Miller started Monday’s game, throwing 1 scoreless, hitless inning on 16 pitches; he walked 1 and didn’t have any K’s
  • Whisenhunt is a 23-year-old who would be making his MLB debut

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cubs at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:29 p.m. ET.

  • Moneyline: Cubs +105 (bet $100 to win $105) | Giants -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-200) | Giants -1.5 (+165)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Cubs at Giants picks and predictions

Prediction

Cubs 4, Giants 2

Moneyline

San Francisco does not have its best foot forward in the mound matchup. Hendricks has been undone by a .331 batting average on balls in play, but he has a fine history against the Giants.

Right-handers put the Giants on the wrong side of their platoon splits: they own a .758 OPS against lefties and a .678 figure against righties.

TAKE CUBS (+105).

Run line/Against the spread

The Cubs (+1.5, -200) play a ton of 1-run games and are a would-be play here. They’re 14-18 in such scenarios. But the -200 juice here is cutting too much into any leverage. PASS.

Over/Under

The total has gone Under in 12 of Chicago’s last 16 games.

With some Under lean coming from Hendricks (BABIP misfortune), both bullpens (both figure as slightly better than what’s indicated by their surface numbers) and recent solid work turned in by Giants relievers specifically, the UNDER 8 (-105) has some value in this one.

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Chicago Cubs at San Francisco Giants odds, picks and predictions

Analyzing Monday’s Chicago Cubs at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (37-41) begin a 4-game series against the San Francisco Giants (36-42) Monday at Oracle Park. First pitch is scheduled for 9:45 p.m. ET (ESPN+). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 2-1

The Cubs and Giants are struggling. Both teams lost Sunday continuing their downward trends.

The Giants were held to 2 hits at St. Louis Cardinals Sunday, but at least both hits brought in runs — C Patrick Bailey’s solo homer PH Wilmer Flores’ RBI double. Unfortunately Giants SP Logan Webb gave up 3 runs in the 1st inning and, in the end, the Giants lost 5-3 — as +110 underdogs with the Over (7) cashing.  — as they were swept in 3 by the Cardinals over the weekend and have lost 5 in a row overall.

The Cubs offense also failed to show up Sunday in a 5-2 home loss as -111 favorites vs. the New York Mets — the Under (8.5) hit. After Mets SP Luis Severino pitched 6 shutout innings of 3-hit ball with no walks and 10 K’s. Once he was removed, Cubs 3B Christopher Morel hit a 2-run homer in the bottom of the 7th inning to cut the deficit to 4-2, but the Mets held on for the win and took 2 of 3 at Wrigley over the weekend.

Cubs at Giants projected starters

LHP Justin Steele vs. LHP Erik Miller

Steele (0-3, 3.16 ERA) makes his 11th start. He has a 1.07 WHIP, 2.4 BB/9 and 8.8 K/9 through 57 innings.

  • Last start: No-decision, 6 2/3 IP, 2 ER, 4 H, 2 BB, 8 K in 5-2 home win vs. Giants Tuesday
  • 2024 road splits: 0-1, 2.51 ERA (28 2/3 IP, 8 ER), 0.90 WHIP, 9.1 K/9 in 5 starts
  • Career vs. Giants: 1-2, 2.31 ERA (23 1/3 IP, 6 ER), 1.20 WHIP, 11.6 K/9 in 4 starts

Miller (2-2, 4.11 ERA) makes his 7th start and 37th appearance in what is expected to be an “opener” role. He has a 1.23 WHIP, 4.4 BB/9 and 10.3 K/9 through 35 innings. The Giants hope RHP Spencer Howard (0-1, 4.86 ERA) can pick up the bulk of the innings once Miller is removed. Howard has a 1.86 WHIP, 4.3 BB/9 and 7.0 K/9 in 16 2/3 innings.

  • Miller’s last outing: No-decision in start, 1 IP, 0 ER, 0 H, 1 BB, 2 K in 6-5 road loss at Cubs Wednesday
  • Allows .171 batting average when batter is ahead in count
  • Posts 1.17 OPS with 2 outs and RISP
  • Spencer’s last outing: 1 IP, 2 ER (3 R), 4 H, 1 BB, 3 K in relief of Miller in Wednesday loss to Cubs

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cubs at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:32 p.m. ET.

  • Moneyline (ML): Cubs -120 (bet $120 to win $100) | Giants +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+145) | Giants +1.5 (-175)
  • Over/Under (O/U): 7.5 (O: -105 | U: -115)

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Cubs at Giants picks and predictions

Prediction

Cubs 6, Giants 4

Moneyline

Steele is the Cubs’ best pitcher and he has yet to earn a win. His road splits show that when he is locked in he can dominate.

The Giants are 5-6 when playing as home underdogs. Plus, after a loss, the Cubs are 24-16, while the Giants are 21-20.

LEAN CUBS (-120).

Run line/Against the spread

The Cubs’ recent woes has makes me skittish on picking them against the spread as favorites. They’re also 14-17 in 1-run games.

AVOID.

Over/Under

The Cubs offense has stalled recently, but the Giants have some good trends toward the Over. San Francisco is 34-24-2 (58.6%) O/U in NL games, the 2nd-best mark in the majors. On no rest, the Over is 37-28-2 (56.9%) for the Giants.

The current line just seems too low. BET OVER 7.5 (-105).

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San Francisco Giants at St. Louis Cardinals odds, picks and predictions

Analyzing Sunday’s San Francisco Giants at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (36-41) and St. Louis Cardinals (38-37) meet Sunday for the finale of a 3-game series. First pitch from Busch Stadium is set for 2:15 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: St. Louis leads 2-0

St. Louis routed San Francisco 9-4 Saturday while covering as a -117 home favorite. The Cardinals scored 7 unanswered runs after being down 4-2 in the 3rd. RHP Miles Mikolas pitched 6 innings with 4 ER, 6 H, 2 BB and 3 K to get the win while OF Alec Burleson hit 2 HRs and had 5 RBIs.

With Thursday’s 6-5 loss to the Cardinals in Birmingham, Ala., the Giants have now lost 4 straight games.

Giants at Cardinals projected starters

RHP Logan Webb vs. RHP Sonny Gray

Webb (6-5, 2.99 ERA) makes his 7th start. He has a 1.19 WHIP, 1.9 BB/9 and 7.5 K/9 in 99 1/3 IP.

  • Last start: No-decision, 7 IP, 2 ER, 6 H, 1 BB, 5 K in a 5-2 loss at the Chicago Cubs Tuesday
  • Career vs. St. Louis: 3-2, 5.17 ERA (31 1/3 IP, 18 ER), 38 H, 9 BB, 25 K in 6 starts

Gray (8-4, 2.95 ERA) makes his 14th start. He has a 1.02 WHIP, 2.6 BB/9 and 11.2 K/9 in 76 1/3 IP.

  • Last start: No-decision, 7 2/3 IP, 2 ER, 5 H, 2 BB, 4 K in a 7-6 win in Miami against the Marlins on Monday
  • Career vs. San Francisco: 2-1, 3.27 ERA (33 IP, 12 ER), 27 H, 14 BB, 30 K in 6 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Giants at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:27 a.m. ET.

  • Moneyline (ML): Giants +105 (bet $100 to win $105) | Cardinals -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-200) | Cardinals -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: +100 | U: -120)

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Giants at Cardinals picks and predictions

Prediction

Cardinals 5, Giants 4

Moneyline

LEAN CARDINALS (-125).

St. Louis is the much hotter team, having won the 1st 2 of this series and going 7-3 in its last 10 games while the Giants have lost 4-straight and are 3-7 in their last 10. The Cardinals are 19-15 at home this year while the Giants are only 16-24 on the road.

This is only a lean because they’ve split their last 6 meetings in St. Louis.

Run line/Against the spread

PASS.

I like the Giants to cover here as their recent matchups vs. St. Louis have been competitive for the most part, but the line is not worth betting on at +1.5 (-200). Bet on the moneyline and/or total instead.

Over/Under

BET OVER 7.5 (+100).

The Over has hit in 3 straight games for San Francisco and is 7-3 in its last 10 games. For St. Louis the Over is 4-1 in its last 5 games. The Over has also hit in each of the last 4 meetings and is 5-1 in the last 6 Cardinals-Giants games in St. Louis.

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San Francisco Giants vs. St. Louis Cardinals odds, picks and predictions

Analyzing Thursday’s San Francisco Giants vs. St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (36-39) take on the St. Louis Cardinals (36-37) Thursday in the opener of a 3-game set at Rickwood Field in Birmingham, Ala., at 7:15 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Giants won 6-1 last year.

This game has been dubbed “MLB at Rickwood Field: A Tribute to the Negro Leagues,” as the game will be played in the home of the Birmingham Black Barons. This game has taken on more significance with the passing of Willie Mays at age 93 Tuesday. St. Louis will be the home team, and after an off-day Friday, the series will shift to Busch Stadium for the final 2 games.

This will be the first MLB game ever at the stadium, which has undergone renovations over the past year to prepare for this game. The dimensions are about 400 feet to center field, 370 to right field and 325 to left, and it has a double decker wall, which may keep more balls in the park. The stadium was always known to be a cavernous pitchers’ park. While the renovations were made to align the park more with present-day stadiums, it could still lean toward pitchers.

The Giants dropped the finale of a 3-game set at Wrigley Field Wednesday 6-5 to drop 2 of 3 in the series. The Giants entered the 8th inning down 6-1, but could not overcome the deficit. DH Jorge Soler hit a grand slam in the 8th for his 9th HR.

The Cards were walked off by the Miami Marlins Wednesday in a 4-3 defeat. They had to go with a bullpen game after RHP Kyle Gibson was scratched minutes before game time with a stiff back. 3B Nolan Arenado (elbow) was hit on the elbow and left the game, and he’s probably questionable for this one.

Giants vs. Cardinals projected starters

RHP Keaton Winn vs. RHP Andre Pallante

Winn (3-7, 6.66 ERA) makes his 12th start. He has a 1.33 WHIP, 3.2 BB/9 and 7.9 K/9 in 52 2/3 IP.

  • Last start: No-decision, 6 IP, 3 ER, 5 H, 2 BB, 6 K Saturday against Los Angeles Angels
  • Has not faced Cardinals
  • Last 5 starts: 0-4, 13.02 ERA (27 ER in 18 2/3 IP)

Pallante (2-3, 4.61 ERA) makes his 5th start and 14th appearance. He has a 1.57 WHIP, 4.0 BB/9 and 6.9 K/9 in 27 1/3 IP.

  • Last start: Loss, 3 1/3 IP, 1 ER, 5 H, 0 BB, 4 K Saturday against Chicago Cubs
  • 4 career relief appearance vs. Giants: 3 2/3 IP, 1 ER (2.45 ERA), 5 H, 4 BB, 1 K
  • In 4 starts this year: 2-2, 3.63 ERA, 1.39 WHIP, 7.8 K/9

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Giants vs. Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:31 a.m. ET.

  • Moneyline (ML): Giants +100 (bet $100 to win $100) | Cardinals -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-210) | Cardinals -1.5 (+155)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Giants vs. Cardinals picks and predictions

Prediction

Giants 5, Cardinals 3

Moneyline

The Giants prevail in Mays’ honor Thursday. The Cards generally struggle against pitchers they haven’t seen before. And if this park holds up to the cavernous settings of yesteryear, that plays against the fly-out-happy Redbirds. The Cards’ pen is also ravaged after 2 extra-inning games and a bullpen game the last 3 days.

Take the GIANTS +100.

Run line/Against the spread

I love KEATON WINN OVER 15.5 OUTS (-110) here. As mentioned, the Cards struggle against pitchers they haven’t faced before. The park’s dimensions should also produce a lot of quick flyouts. Winn went 6 IP in his last start, and he should approach that in this game.

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Over/Under

The Cards are 2-8 O/U over their last 10, and the Giants are 6-4. Pallante is a ground-ball pitcher who has fared well in the rotation. The Giants are tied for 12th with 4.4 R/game, and the Cards are tied for 24th with 3.9 R/game.

It’ll be close, but I LEAN UNDER 8.5 (-105).

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San Francisco Giants at Chicago Cubs odds, picks and predictions

Analyzing Wednesday’s San Francisco Giants at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (36-38) and Chicago Cubs (35-39) wrap up a 3-game set at Wrigley Field Wednesday. First pitch is scheduled for 2:20 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Giants vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

After a 7-6 series-opening win, the Giants lost 5-2 as +105 underdogs Tuesday as the Under (9.5) hit. San Francisco has lost 3 of its last 5 games.

Cubs CF Cody Bellinger hit a go-ahead RBI single in the 8th inning, breaking a 2-2 tie. The win snapped a 2-game skid for Chicago, which cashed as a -114 favorite.

Giants at Cubs projected starters

TBD vs. RHP Kyle Hendricks

The Giants had not yet named a starter. RHP Spencer Howard (0-1, 4.02 ERA) started Friday after RHP Logan Webb‘s spot in the rotation and could be an option for the series finale. Howard has a 1.66 WHIP, 4.0 BB/9 and 5.7 K/9 in 2 starts and 2 relief appearances.

  • Howard last start: Loss, 2 1/3 IP, 4 ER, 7 H, 4 BB, 1 K in Friday’s 8-6 home defeat vs. Los Angeles Angels
  • Howard 2024 road stats: 0-0, 2.89 ERA (9 1/3 IP, 3 ER), 1.07 WHIP, 4.8 K/9 in 1 start and 1 relief appearance

Hendricks (0-4, 8.20 ERA) makes his 8th start and 13th appearance. He has a 1.71 WHIP, 3.0 BB/9 and 6.2 K/9 in 45 IP.

  • Last outing: No-decision, 4 1/3 relief IP, 0 R, 2 H, 0 BB, 1 K in 3-0 home loss vs. St. Louis Cardinals Friday
  • Last start: Loss, 4 2/3 IP, 7 ER (8 R), 11 H, 0 BB, 4 K in 9-3 home setback vs. Pittsburgh Pirates May 17
  • 2024 home stats: 0-2, 7.36 ERA (22 IP, 18 ER), 1.77 WHIP, 7.4 K/9 in 3 starts and 3 relief appearances
  • Career vs. Giants (regular season): 6-2, 2.36 ERA (76 1/3 IP, 20 ER), 0.94 WHIP, 7.2 K/9 in 12 starts, including 1-0 with 2.70 ERA (13 1/3 IP, 4 ER) in 2 starts last year

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Giants at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:21 a.m. ET.

  • Moneyline (ML): Giants +102 (bet $100 to win $102) | Cubs -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants -1.5 (+152) | Cubs +1.5 (-184)
  • Over/Under (O/U): 11.5 (O: +104 | U: -128)

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Giants at Cubs picks and predictions

Prediction

Giants 5, Cubs 4

Moneyline

The GIANTS (+102) would be my lean with Hendricks starting for the Cubs. While the uncertainty at starting pitcher for San Francisco definitely gives me pause, in no scenario do I want to bet the Cubs with Hendricks on the mound unless I’m getting plus money.

LEAN GIANTS (+102).

Run line/Against the spread

It’s tough for me to feel confident in the run line either way without a starting pitcher confirmed for San Francisco. However, the Cubs have lost by multiple runs in Hendricks’ last 6 outings.

I would still PASS on the run line, though, until the Giants officially announce a starter. Bet the ML and/or total instead.

Over/Under

While Hendricks has allowed 4 ER or more in 6 of his 7 starts this season, this number seems a bit too high. The Cubs offense has been underperforming recently, and the Under is 10-1 in their last 11 games.

BET UNDER 11.5 (-128).

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[gambcom-standard rankid=”5″ ]

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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San Francisco Giants at Chicago Cubs odds, picks and predictions

Analyzing Tuesday’s San Francisco Giants at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (36-37) and Chicago Cubs (34-39) play the 2nd game of a 3-game set Tuesday. First pitch from Wrigley Field is scheduled for 8:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0

The Giants won 7-6 as +103 underdogs in the series opener Monday as the Over (10) hit.

Giants 2B Thairo Estrada hit a go-ahead 3-run HR in the 9th inning, the Cubs’ 16th blown save this year (2nd-most in MLB). LF Heliot Ramos and C Patrick Bailey also hit HRs for San Francisco, which came back from a 3-run, 8th-inning deficit.

Giants at Cubs projected starters

RHP Logan Webb vs. LHP Justin Steele

Webb (6-5, 3.02 ERA) makes his 15th start. He has a 1.20 WHIP, 1.9 BB/9 and 7.6 K/9 in 92 1/3 innings.

  • Last start: Win, 6 IP, 3 ER, 7 H, 0 BB, 5 K in 5-3 home victory against Houston Astros Wednesday
  • 2024 road splits: 2-3, 4.06 ERA (44 1/3 IP, 20 ER), 1.35 WHIP, 8.9 K/9 in 8 starts

Steele (0-3, 3.22 ERA) makes his 10th start. He has a 1.09 WHIP, 2.3 BB/9 and 8.6 K/9 in 50 1/3 innings.

  • Last start: No-decision, 6 IP, 0 R, 3 H, 1 BB, 5 K in 3-2 road loss to Tampa Bay Rays Thursday
  • 2024 home splits: 0-2, 4.15 ERA (21 2/3 IP, 10 ER), 1.34 WHIP, 7.9 K/9 in 4 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Giants at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:35 a.m. ET.

  • Moneyline (ML): Giants -115 (bet $115 to win $100) | Cubs -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants -1.5 (+140) | Cubs +1.5 (-165)
  • Over/Under (O/U): 9.5 (O: -110 | U: -110)

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Giants at Cubs picks and predictions

Prediction

Giants 3, Cubs 0

Moneyline

The Giants are 5-1 since May following a series-opening win, while the Cubs are coming off a heartbreaking home loss and dealing with a struggling bullpen.

LEAN GIANTS (-115).

Run line/Against the spread

While I like the Giants Tuesday, both teams have had their fair share of 1-run scores. I would PASS here and stick with the moneyline.

Over/Under

The Cubs have the best Under record after a loss this season at 23-13-2 (63.9%). Steele also hasn’t given up more than 1 run in each of his last 4 starts.

Webb hasn’t been as dominant lately, giving up 7 or more hits and 3-plus runs in 2 of his last 3 starts. However, the Cubs are batting just .214 with RISP, the 3rd-lowest mark in MLB, which will give the Giants plenty of opportunities to get out of a jam.

BET UNDER 9.5 (-110).

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[gambcom-standard rankid=”5″ ]

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Houston Astros at San Francisco Giants odds, picks and predictions

Analyzing Wednesday’s Houston Astros at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (31-37) and San Francisco Giants (33-35) meet Wednesday for the finale of a 3-game series. First pitch from Oracle Park is set for 3:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

Houston beat San Francisco 3-1 in the 2nd game of the series Tuesday while cashing as a +103 road underdog. The Astros broke the 1-1 tie in the top of the 5th innings thanks to an error by 3B Matt Chapman. Tuesday’s win snapped a 2-game losing skid for Houston.

RHP Jordan Hicks picked up the loss for San Francisco, allowing 3 ER on 5 hits and 1 walk with 5 K’s in 4 2/3 innings. The Giants have lost 2 of their last 3 outings.

Astros at Giants projected starters

LHP Framber Valdez vs. RHP Logan Webb

Valdez (5-3, 3.53 ERA) makes his 11th start. He has a 1.15 WHIP, 2.5 BB/9 and 7.1 K/9 in 63 2/3 innings.

  • Last start: Win, 9 IP, 1 ER, 4 H, 1 BB, 8 K in 7-1 victory at Los Angeles Angels Friday
  • Career vs. San Francisco: 1-1, 3.27 ERA (11 IP, 4 ER), 1.27 WHIP, 11.5 K/9 in 2 starts

Webb (5-5, 2.92 ERA) makes his 15th start. He has a 1.20 WHIP, 2.1 BB/9 and 7.6 K/9 in 86 1/3 innings.

  • Last start: Win, 7 IP, 2 ER, 5 H, 0 BB, 6 K in 5-2 victory at Texas Rangers Friday
  • Career vs. Houston: 2-1, 3.18 ERA (17 IP, 6 ER), 1.18 WHIP, 5.8 K/9 in 3 starts

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Astros at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:30 a.m. ET.

  • Moneyline (ML): Astros -105 (bet $105 to win $100) | Giants -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+165) | Giants +1.5 (-200)
  • Over/Under (O/U): 7.5 (O: +100 | U: -120)

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Astros at Giants picks and predictions

Prediction

Giants 3, Astros 1

Moneyline

LEAN GIANTS (-115).

San Francisco is 3-1 in the last 4 meetings overall and 3-1 in the last 4 meetings at Oracle Park.

This is only a lean because the Astros enter as the slightly hotter team, going 6-4 in their last 10 games overall and 3-2 in their last 5 on the road, while the Giants are only 4-6 in their last 10 and 1-4 in their last 5 at home.

Run line/Against the spread

PASS.

I like the Giants to cover here as +1.5 (-200) underdogs, but the line is simply not worth the risk of betting on at this price. Bet on the moneyline and/or total instead.

Over/Under

BET UNDER 7.5 (-120).

The Under has hit in 4 of Houston’s last 5 road games and is 7-3 in its last 10 overall. For San Francisco, the Under is 4-1 in its last 5 outings. The Under has also hit in each of the last 4 Houston-San Francisco matchups overall and is 3-0 in the last 3 meetings in the Bay Area.

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[gambcom-standard rankid=”5″ ]

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Additional MLB coverage:
BaseballHQ Fantasy Baseball

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Houston Astros at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s Houston Astros at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (30-37) and San Francisco Giants (33-34) play the 2nd game of a 3-game set at Oracle Park Tuesday. First pitch is scheduled for 9:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0

The Astros lost 4-3 in 10 innings as -114 road favorites in the series opener Monday as the Under (8) hit. Houston has lost back-to-back games for the 1st time since a 3-game skid May 27-29.

RF Austin Slater hit a game-winning single for the Giants, who rallied back from a 2-run deficit in the 10th inning. San Francisco has won 4 of its last 5 games.

Astros at Giants projected starters

RHP Ronel Blanco vs. RHP Jordan Hicks

Blanco (5-2, 2.78 ERA) makes his 12th start. He has a 1.05 WHIP, 3.8 BB/9 and 8.2 K/9 in 64 2/3 IP.

  • Last start: Loss, 5 2/3 IP, 4 ER, 5 H, 2 BB, 2 K in 4-2 home setback vs. St. Louis Cardinals Wednesday
  • 2024 road stats: 4-0, 2.08 ERA (30 1/3 IP, 7 ER), 1.09 WHIP, 8.6 K/9 in 5 starts

Hicks (4-2, 2.82 ERA) makes his 14th start. He has a 1.19 WHIP, 3.1 BB/9 and 7.9 K/9 in 67 IP.

  • Last start: No-decision, 3 2/3 IP, 2 ER, 6 H, 4 BB, 7 K in 9-3 win at Arizona Diamondbacks Wednesday
  • 2024 home stats: 2-1, 2.52 ERA (39 1/3 IP, 11 ER), 0.99 WHIP, 5.7 K/9 in 7 starts

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Astros at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:26 p.m. ET.

  • Moneyline (ML): Astros -105 (bet $105 to win $100) | Giants -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+155) | Giants +1.5 (-190)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Astros at Giants picks and predictions

Prediction

Astros 3, Giants 2

Moneyline

The ASTROS (-105) are 4-1 in their last 5 outings after a loss and should bounce back against the inconsistent Giants, who are 4-7 over their last 11 games. Blanco has yet to lose a decision on the road this season, and Hicks has allowed a total of 7 runs over his last 2 starts (9 IP).

BET ASTROS (-105).

Run line/Against the spread

San Francisco +1.5 (-190) will probably hit, but it’s hard to beat MLB long term betting into markets with this much vig.

PASS. Bet the ML and/or total instead.

Over/Under

Blanco has allowed 2 ER or fewer in all 4 road starts this season, and Hicks has given up 2 or fewer runs in 6 of his 7 appearances at Oracle Park. The Under has hit in 4 of 5 games for the Astros and 3 of 4 for San Francisco.

BET UNDER 8 (-115).

Play our free daily Pick’em Challenge and win! Play now!

[gambcom-standard rankid=”5″ ]

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Corey Scott on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Additional MLB coverage:
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