San Francisco Giants betting odds line spread pick predictions best bets

New York Mets at San Francisco Giants odds, picks and predictions

Analyzing Wednesday’s New York Mets at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The New York Mets (12-11) and San Francisco Giants (12-13) wrap up a 3-game series at Oracle Park Wednesday. First pitch is scheduled for 3:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Mets vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 2-0

The Mets have lost 3 games in a row after falling 5-1 against the Giants Tuesday and failing to cash as +117 road underdogs. New York avoided the shutout with a 9th-inning RBI from DH DJ Stewart. RHP Luis Severino picked up the loss after allowing 3 earned runs in 6 innings.

San Francisco has won back-to-back games after Tuesday’s victory as a -127 home favorite. RF Mike Yastrzemski led the way with 3 RBIs while the Giants had 9 hits. RHP Logan Webb pitched 6 scoreless innings to pick up the win.

Mets at Giants projected starters

LHP Sean Manaea vs. LHP Blake Snell

Manaea (1-1, 4.12 ERA) makes his 5th start. He has a 1.37 WHIP, 4.6 BB/9 and 9.6 K/9 in 19 2/3 innings.

Mets are 2-2 in his starts
Has allowed 2 or fewer ER in 3 of his 4 starts
Has given up just 1 HR this season while striking out 21 and walking 10

Snell (0-3, 11.57 ERA) makes his 4th start. He has a 1.97 WHIP, 3.9 BB/9 and 9.3 K/9 in 11 2/3 innings.

Giants are 0-3 in his starts
Has allowed 5 or more ER in 2 of his 3 starts
Has pitched 4 2/3 innings or fewer in each start
Has allowed 15 ER and 2 HR this season while striking out 12 and and walking 5

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Mets at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:40 a.m. ET.

Moneyline (ML): Mets +110 (bet $100 to win $110) | Giants -130 (bet $130 to win $100)
Run line (RL)/Against the spread (ATS): Mets +1.5 (-190) | Giants -1.5 (+155)
Over/Under (O/U): 7.5 (O: +100 | U: -120)

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Mets at Giants picks and predictions

Prediction

Mets 7, Giants 4

Moneyline

BET METS (+110).

While New York has lost 3 games in a row, it has won 6 of its last 9. The Mets have struggled offensively in their last 3 games, but this time around they face Snell, who has had a tough start to the season.

The Giants fell 17-1 in his last start, and the opposing team has scored 8 or more runs in each of Snell’s previous 3 starts.

Run line/Against the spread

PASS.

The moneyline presents more profit for the Mets.

Over/Under

BET OVER 7.5 (+100).

The Mets have hit the Over in 5 of their last 8 games and scored 6 or more runs in 5 of their last 10.

The Giants have scored 5 runs in each of the 1st 2 games this series and 5 or more runs in 4 of their last 6.

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New York Mets at San Francisco Giants odds, picks and predictions

Analyzing Monday’s New York Mets at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The New York Mets (12-9) and San Francisco Giants (10-13) open a 3-game series at Oracle Park Monday. First pitch is scheduled for 9:45 p.m. ET (ESPN+). Let’s analyze BetMGM Sportsbook’s lines around the Mets vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Mets won 4-3 last season

The Mets are coming off a 10-0 loss at the Los Angeles Dodgers Sunday with the Over (9) cashing in Southern California. New York, which was a +214 underdog, had won 6 straight and back-to-back games as an underdog of +151 or more.

The Giants, who were -131 home favorites, lost 5-3 against the Arizona Diamondbacks Sunday as the total (8) pushed. San Francisco has alternated wins and losses over its last 4 games and is 8-8 in its last 16.

Mets at Giants projected starters

LHP José Quintana vs. RHP Keaton Winn

Quintana (1-1, 3.05 ERA) makes his 5th start. He has a 1.50 WHIP, 4.8 BB/9 and 7.0 K/9 in 20 2/3 innings.

Last start: No-decision, 5 IP, 1 ER, 4 H, 3 BB, 4 K in 3-1 home victory vs. Pittsburgh Pirates Tuesday
2024 road stats: 1-0, 3.27 ERA (11 IP, 4 ER), 1.46 WHIP in 2 starts
Career vs. Giants: 1-3, 4.30 ERA (29 1/3 IP, 14 ER), 1.13 WHIP in 5 starts and 1 relief appearance — last faced San Francisco in 2022

Winn (1-3, 4.09 ERA) makes his 5th start. The rookie has a 1.09 WHIP, 3.3 BB/9 and 7.0 K/9 in 22 innings.

Last start: Win, 6 IP, 1 ER, 4 H, 1 BB, 4 K in 3-1 victory at Miami Marlins Wednesday
2024 home stats: Loss, 6 IP, 4 ER, 3 H, 3 BB, 1 K in 1 start, a 4-0 loss to San Diego Padres April 6
Has never faced Mets before

Mets at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:49 a.m. ET.

Moneyline (ML): Mets -105 (bet $105 to win $100) | Giants -115 (bet $115 to win $100)
Run line (RL)/Against the spread (ATS): Mets -1.5 (+155) | Giants +1.5 (-190)
Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Mets at Giants picks and predictions

Prediction

Mets 5, Giants 4

Moneyline

The METS (-105) have not lost back-to-back outings since they opened the season on a 5-game skid from March 29-April 4. Since then, they’re 12-4 overall and 5-3 as underdogs. Quintana has also been slightly better than expected, allowing 2 earned runs or fewer in 3 of his 4 starts.

BET METS (-105).

Run line/Against the spread

Taking New York as a slight underdog to win straight up is the safer play in this series opener. The Mets should bounce back after getting blown out at the Dodgers last time out, but it’s unlikely they win by 2 or more runs.

PASS. Bet Mets ML and/or the total instead.

Over/Under

The Over is 7-2 when the Mets are on the road this season, which is the highest clip in MLB for a team’s away games. The Mets are also 4-0 to the Over in their last 4 games.

Winn’s worst outing of the season so far was his only home start April 6 when he gave up 4 earned runs to the Padres, who average 1.31 fewer runs per road game than the Mets.

BET OVER 8.5 (-105).

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Arizona Diamondbacks at San Francisco Giants odds, picks and predictions

Analyzing Saturday’s Arizona Diamondbacks at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (10-11) and San Francisco Giants (9-12) play the 3rd game of their 4-game series Saturday afternoon. First pitch from Oracle Park is at 4:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1.

After getting shut out 5-0 in the opener, the Diamondbacks exploded for a 17-1 win in starter Jordan Montgomery’s debut for the team. He allowed 1 run in 6 innings. They are 4-3 in their last 7 games.

The Giants had their 2-game winning streak snapped. They have won 4 of their last 6 games. 3B Matt Chapman has provided a jolt to the offense with 9 extra-base hits, 12 RBI and 12 R on the young season.

Diamondbacks at Giants projected starters

RHP Zac Gallen vs. LHP Kyle Harrison

Gallen (3-0, 1.64 ERA) makes his 5th start. He has a 1.14 WHIP, 2.9 BB/9 and 10.6 K/9 through 22 IP.

Last start: Win, 6 IP, 0 R, 4 H, 2 BB, 7 K in 5-0 home win over Cardinals on Sunday
Has allowed 1 or fewer runs in 3 of his 4 starts

Harrison (2-1, 4.70 ERA) makes his 5th start. He has a 1.26 WHIP, 1.6 BB/9 and 7.4 K/9 through 23 IP.

Last start: Win, 6 IP, 3 ER, 8 H, 1 BB, 2 K in 4-3 road win over Miami on Monday
Has allowed 3+ runs in 3 of 4 starts this season

Diamondbacks at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:15 a.m. ET.

Moneyline (ML): Diamondbacks -125 (bet $125 to win $100) | Giants +105 (bet $100 to win $105)
Run line (RL)/Against the spread (ATS): Diamondbacks -1.5 (+140) | Giants +1.5 (-165)
Over/Under (O/U): 8 (O: -105 | U: -115)

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Diamondbacks at Giants picks and predictions

Prediction

Diamondbacks 5, Giants 2

Moneyline

Gallen has been great this season. He allowed 3 of his 4 ER on the road this season but has allowed only 1 run in his 3 other starts, and Arizona is 3-1 when he is on the mound.

The Giants lost Harrison’s only home start this season, a 5-3 loss to Washington on April 9. He allowed 3 runs in 6 innings.

Betting the Diamondbacks to win isn’t a bad bet at -125, but their track record this season with Gallen on the mound makes the run line and the plus-odds there even better.

PASS.

Run line/Against the spread

The Diamondbacks have scored 5 or more runs in all Gallen’s starts. All 3 wins when he started were by multiple runs.

Six of the Giants’ last 7 losses were by more than 1 run.

Nine of the Diamondbacks’ 10 wins have been by multiple runs.

BET DIAMONDBACKS -1.5 (+140).

Over/Under

Seven of Arizona’s last 10 games have had 8 or fewer total runs.

Seven of the last 9 meetings between the 2 teams have had 8 it fewer runs.

BET UNDER 8 (-115).

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Arizona Diamondbacks at San Francisco Giants odds, picks and predictions

Analyzing Friday’s Arizona Diamondbacks at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (9-11) and San Francisco Giants (9-11) play the 2nd game of a 4-game series Friday. First pitch from Oracle Park is at 10:15 p.m. ET (Apple TV+). Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0

The Diamondbacks have lost 2 straight and 3 of their last 4. They opened the series with a 5-0 loss Thursday as starting RHP Ryne Nelson was forced to leave in the 2nd inning after getting hit by a line drive on his pitching arm. It was the 1st time they were shut out this season.

The Giants have won back-to-back games for the 2nd time this season. They have won 3 of their last 4 games.

Diamondbacks at Giants projected starters

LHP Jordan Montgomery vs. LHP Blake Snell

Montgomery (10-11, 3.20 ERA in 2023) makes his 2024 debut. He had a 1.19 WHIP, 2.3 BB/9 and 7.9 K/9 through 188 2/3 IP in 32 starts last season with the St. Louis Cardinals and Texas Rangers.

Went 3-1 with a 2.90 ERA in 5 postseason appearances last year for the World Series champion Rangers
0-2 with a 2.19 ERA in 2 career starts vs. Giants

Snell (0-2, 12.86 ERA) makes his 3rd start. He has a 1.86 WHIP, 4 BB and 9 K in 7 innings.

Last start: Loss, 4 IP, 7 ER, 6 H, 2 BB, 4 K in 9-4 road loss to Tampa Bay Rays Sunday
5-1 with a 1.11 ERA in 8 career starts vs. Arizona

Diamondbacks at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:45 a.m. ET.

Moneyline (ML): Diamondbacks +110 (bet $100 to win $110) | Giants -130 (bet $130 to win $100)
Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-190) | Giants -1.5 (+155)
Over/Under (O/U): 7.5 (O: -110 | U: -110)

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Diamondbacks at Giants picks and predictions

Prediction

Giants 4, Diamondbacks 3

Moneyline

Arizona (+110) has been waiting for the debut of Montgomery, as LHP Eduardo Rodriguez was placed on the 60-day IL.

But the issue for Arizona has mostly been the back end of the bullpen while closer Paul Sewald has been out. It has already blown 5 save opportunities in 20 games.

Snell has struggled early on but has been nearly perfect in his career against Arizona.

Montgomery probably won’t go deep into the game in his debut, so Arizona will need to rely on the bullpen.

BET GIANTS (-130).

Run line/Against the spread

Three of the Giants’ last 7 wins have been by only 1 run. The Diamondbacks have four 1-run losses this season.

Betting the D’Backs to cover +1.5 at -190 isn’t a good bet, but with Snell’s struggles early this season, despite his career numbers against Arizona, this feels like a game where Arizona has a lead from a strong Montgomery debut, only to have the bullpen fail.

PASS.

Over/Under

Both of Snell’s starts this season have had 9 or more total runs.

Five of Arizona’s last 6 games have not reached 9 total runs.

The Giants’ last 2 games have not reached 9 total runs, but 3 of their last 6 have.

Seven of the last 8 meetings have not reached 9 runs.

BET UNDER 8 (-110).

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Arizona Diamondbacks at San Francisco Giants odds, picks and predictions

Analyzing Thursday’s Arizona Diamondbacks at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (9-10) and San Francisco Giants (8-11) open a 4-game series at Oracle Park Thursday. First pitch is scheduled for 9:45 p.m. ET (FS1). Let’s analyze FanDuel Sportsbook’s lines around the Diamondbacks vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Diamondbacks won 7-6 last season

The Diamondbacks lost to the Chicago Cubs 5-3 Wednesday, closing as -122 favorites. They lost 2 of 3 in that series yet have won 5 of their last 8. Arizona is 10-9 against the spread (ATS).

The Giants beat the Miami Marlins 3-1 on the road Wednesday, winning 2 of 3 in that series. They have traded off winning and losing in their last 8 games and are 8-11 ATS on the season.

Diamondbacks at Giants projected starters

RHP Ryne Nelson vs. RHP Logan Webb

Nelson (1-2, 5.27 ERA) makes his 4th start. He has a 1.61 WHIP, 3.3 BB/9 and 8.6 K/9 in 13 2/3 innings.

Last start: Win, 6 IP, 1 ER, 7 H, 1 BB, 4 K in 4-2 home victory vs. St. Louis Cardinals Saturday
2023 road splits: 6-3, 3.46 ERA (88 1/3 IP, 34 ER — 12 HR), 23 BB, 65 K in 15 starts and 1 relief appearance

Webb (1-1, 3.80 ERA) makes his 5th start. He has a 1.39 WHIP, 1.9 BB/9 and 6.5 K/9 in 23 2/3 innings.

Last start: Win, 7 IP, 1 ER, 6 H, 1 BB, 4 K in 11-2 victory at Tampa Bay Rays Saturday
2023 home splits: 7-6, 2.26 ERA (111 2/3 IP, 28 ER — 8 HR), 15 BB, 100 K in 16 starts

Diamondbacks at Giants odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:45 a.m. ET.

Moneyline (ML): Diamondbacks +144 (bet $100 to win $144) | Giants -172 (bet $172 to win $100)
Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-152) | Giants -1.5 (+126)
Over/Under (O/U): 7.5 (O: -118 | U: -104)

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Diamondbacks at Giants picks and predictions

Prediction

Giants 4, Diamondbacks 3

Moneyline

PASS.

There’s not great value here either way, and the Giants (-172) have lost 2 of their last 3 at home and are 3-3 straight up at Oracle Park this season. Their value isn’t great here, and it should be avoided.

Run line/Against the spread

BET DIAMONDBACKS +1.5 (-152).

The Giants have traded off winning and losing in 8 straight games, and that has expanded through all or part of 3 series. San Fran has dropped 3 of its last 5 at home and is just 1-5 ATS at home, winning by 1 in 2 of its 3 wins.

The Diamondbacks, on the other hand, have played 6 games as on the road and lost in Atlanta by 1 in 2 of those. They are 3-3 ATS away. While Nelson hasn’t been as consistent as Webb this season, he was strong on the road last season. Expect the Diamondbacks to keep this one close.

Take DIAMONDBACKS +1.5 (-152).

Over/Under

LEAN UNDER 8 (-172).

The Diamondbacks have gone Under in 4 of their last 5 games, and they are 0-3 O/U in Nelson’s 3 starts this season.

Arizona is 9-10 O/U on the season. The Giants have gone Under in 5 of their last 8 games. They have scored 4 or fewer in 4 straight games and have allowed 3 or fewer in 2 of their last 3.

Considering the strength of the starting pitching as well, back UNDER 8 (-172).

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San Francisco Giants at Los Angeles Dodgers odds, picks and predictions

Analyzing Wednesday’s San Francisco Giants at Los Angeles Dodgers odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (2-4) and Los Angeles Dodgers (6-2) meet Wednesday as they close out a 3-game series at Dodger Stadium. First pitch is slated for 10:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Dodgers odds and make our expert MLB picks and predictions for the best bets.

Season series: Dodgers lead 2-0

San Francisco dropped Tuesday’s game 5-4 to log its 3rd straight setback. The Giants have lost 6 of their last 7 games against Los Angeles.

The Dodgers are thus far 5-1 at Dodger Stadium (L.A. also had 1 home game in Seoul, South Korea). Los Angeles pitching owns a 2.78 ERA, 1.04 over those games in their home yard.

Giants at Dodgers projected starters

LHP Kyle Harrison vs. RHP Tyler Glasnow

Harrison (1-0, 3.00 ERA) is tabbed for his 2nd start this season. He allowed 2 ER on 6 H and 0 BB with 5 K in 6 IP in his debut at the San Diego Padres Friday.

Posted a 4.15 ERA, 1.15 WHIP in a 7-start 2023 rookie season
Career vs. Dodgers: 0-0, 1.74 ERA (10 1/3 IP, 2 ER), 3 H, 3 BB, 6 K in 2 starts

Glasnow (1-0, 2.45 ERA) makes his 3rd start. He has a 0.82 WHIP, 4.1 BB/9 and 6.6 K/9 in 11 innings.

Owns a 3.86 ERA, 1.20 WHIP across 129 career games; logged a 3.53 ERA for the Tampa Bay Rays in 2023
Makes this start on 5-day rest, which figures as his preferred interval (.623 OPS allowed)
Last outing: Win, 6 IP, 1 ER, 2 H, 1 BB, 5 K in 7-1 win vs. St. Louis Cardinals
Career vs. Giants: 2-0, 0.64 ERA (14 IP, 1 ER), 8 H, 5 BB, 16 K in 2 starts and 1 relief appearance

Giants at Dodgers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:45 a.m. ET.

Moneyline: Giants +180 (bet $100 to win $180) | Dodgers -225 (bet $225 to win $100)
Run line (RL)/Against the spread (ATS): Giants +1.5 (-105) | Dodgers -1.5 (-115)
Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Giants at Dodgers picks and predictions

Prediction

Dodgers 4, Giants 2

Moneyline

Lots of juice clouding profit potential here. PASS.

Run line/Against the spread

Harrison was aided by a .236 batting average on balls in play last season. Glasnow’s early-season stuff has often been dominant over his career (.584 OPS allowed).

Peg a moderate lean on the DODGERS -1.5 (-115).

Over/Under

The Over is 4-0-1 across L.A.’s last 4 games and is undefeated across the Giants’ 6 games this season.

But there is some lean toward a pushback in Wednesday’s series finale. Most of that comes from the L.A. side of the equation, with Glasnow being a pick to click and on the Dodgers’ offensive numbers being a bit overcooked by a .358 batting average on balls in play (.379 BABIP with runners in scoring position) and a 17.1% of fly balls landing as home runs.

The back ends of both bullpens figure as mostly available.

Consider a partial-unit play on the UNDER 8.5 (-115).

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San Francisco Giants at Los Angeles Dodgers odds, picks and predictions

Analyzing Tuesday’s San Francisco Giants at Los Angeles Dodgers odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (2-3) and Los Angeles Dodgers (5-2) continue a 3-game NL West series Tuesday night. First pitch at Dodger Stadium is slated for 10:10 p.m. ET (TBS). Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Dodgers odds and make our expert MLB picks and predictions for the best bets.

Season series: Dodgers lead 1-0

San Francisco went 1-for-7 with runners in scoring position in dropping Monday’s series opener 8-3. The Giants are 1 for their last 14 in such situations.

The Dodgers are thus far 5-1 at Dodger Stadium (they also had 1 home game in Seoul, South Korea). Los Angeles pitching has been sharp at home, logging a 2.54 ERA and 0.98 WHIP.

Giants at Dodgers projected starters

RHP Logan Webb vs. Undecided

Webb (0-0, 3.00 ERA) makes his 2nd start of the season. He has a 1.17 WHIP, 3.0 BB/9 and 7.5 K/9 through 6 IP.

Owns a 3.07 ERA over the last 3 seasons
Last outing: Loss, 6 IP, 2 ER, 5 H, 2 BB, 5 K in 6-4 loss at San Diego Padres
Career vs. Dodgers: 3-5, 3.96 ERA (63 2/3 IP, 28 ER), 63 H, 18 BB, 51 K
Per ESPN, current Dodger bats own an aggregate .895 OPS against him

The Dodgers are expected to go with bullpen options to make their way through Tuesday’s game.

RHP Michael Grove and LHP Ryan Yarbrough figure as likely sources of bulk innings

Giants at Dodgers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:49 a.m. ET.

Moneyline: Giants +120 (bet $100 to win $120) | Dodgers -145 (bet $145 to win $100)
Run line (RL)/Against the spread (ATS): Giants +1.5 (-165) | Dodgers -1.5 (+140)
Over/Under (O/U): 8.5 (O: +100 | U: -120)

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Giants at Dodgers picks and predictions

Prediction

Giants 5, Dodgers 4

Moneyline

San Francisco is a respectable 4-4 over its last 8 games at Dodger Stadium. The Giants were a solid preseason futures play and figure to be a tad undervalued here.

But bullpen games, especially early-season ones, draw a caution flag in this corner. Consider a pass and going with just the stronger Over bet or going in small — like half of a half of a unit small — on the visiting GIANTS +120.

Run line/Against the spread

PASS: Better relative value can be found elsewhere.

Over/Under

The Over hit Monday and is 3-0-1 across the Dodgers’ last 4 games and is undefeated across the Giants’ 5 games this season.

Los Angeles has had few problems against Webb in the past. The San Francisco right-hander is durable and can usually get fairly deep into games, but this is start No. 2 and he did register 97 pitches in his debut effort. What’s behind him are the Over-worthy numbers thus far posted by the Giants bullpen. Through 16 innings, San Francisco relievers own a 10.12 ERA.

On what is expected to be a breeze-blowing-out night at Chavez Ravine, BACK THE OVER 8.5 (+100).

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San Francisco Giants at Los Angeles Dodgers odds, picks and predictions

Analyzing Monday’s San Francisco Giants at Los Angeles Dodgers odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (2-2) and Los Angeles Dodgers (4-2) open a 3-game NL West rivalry set Monday night. First pitch at Dodger Stadium is slated for 10:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Dodgers odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Los Angeles won last year’s series 7-6

San Francisco took 2 of 4 games in a season-opening series at the San Diego Padres. Giants pitching was touched up for a 6.35 ERA in the 4 games.

The Dodgers remain at home after taking 3 of 4 games against the St. Louis Cardinals. L.A. pitching filed a 2.68 ERA and 10.8 strikeouts per 9 IP in the quartet of games in Chavez Ravine.

Giants at Dodgers projected starters

RHP Keaton Winn vs. LHP James Paxton

Winn makes his season debut. In his rookie 2023 campaign, he went 1-3 with a 4.68 ERA, 1.04 WHIP, 1.7 BB/9 and 7.4 K/9 in 42 1.3 IP.

Did not make his Cactus League debut until March 17 after experiencing elbow soreness in late-February.
Will likely be on a relatively limited pitch count (threw 42 pitches in his 2nd of just 2 spring-training outings)
Career vs. Dodgers: 0-1, 10.13 ERA (5 1/3 IP, 6 ER), 6 H, 0 BB, 5 K in 1 start

Paxton is making his season debut. Pitching 19 games for the Boston Red Sox in 2023, the veteran lefty went 7-5 with a 4.50 ERA, 1.31 WHIP, 3.1 BB/9 and 9.5 K/9 in 96 IP.

Limited to just 6 starts from 2020-22 due to injuries and was shut down with a knee injury in early September last season
Struggled after the All-Star break, notching a 6.98 ERA
Career vs. Giants: 1-0, 3.38 ERA (10 2/3 IP, 4 ER), 13 H, 4 BB, 13 K in 2 starts

Giants at Dodgers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:13 a.m. ET.

Moneyline: Giants +185 (bet $100 to win $185) | Dodgers -225 (bet $225 to win $100)
Run line (RL)/Against the spread (ATS): Giants +1.5 (-110) | Dodgers -1.5 (-110)
Over/Under (O/U): 9 (O: +100 | U: -120)

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Giants at Dodgers picks and predictions

Prediction

Dodgers 6, Giants 4

Moneyline

PASS: The run line in this one offers up drier (less juice) tags.

Run line/Against the spread

San Francisco’s 2 losses have been by multiple runs; 3 of the Dodgers’ 4 wins have been by multi-run margins.

Los Angeles has taken 4 of the last 5 meetings against their Northern California rivals. Three of those wins were by 3 runs or more. Over 2022-23, the Dodgers played .679 (110-52) baseball in Chavez Ravine, and regardless of the many home parks he has toiled in, Paxton has usually been a much better pitcher in home environs.

Winn faced the Dodgers once last season (Sept. 29) and was rocked, allowing 6 runs (3 home runs) in 5 1/3 IP.

FanDuel Sportsbook has a better value on the Dodgers RL play. Back the DODGERS -1.5 (-102).

Over/Under

The San Francisco offense figures to be solid in 2024, and the Dodgers are loaded up and down the lineup.

Both starters have question marks. With the season getting underway in earnest Thursday, both bullpens are 4 days more tangled than they were in the freshness of Opening Day air.

The Los Angeles weather report is calling for a double-digit wind blowing out, and that could mean an extra run or more on the odd potential wall-scraper or would-be long fly landing for extra bases.

FanDuel’s price here makes for extra leverage. TAKE THE OVER 8.5 (-110).

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San Francisco Giants at San Diego Padres odds, picks and predictions

Analyzing Sunday’s San Francisco Giants at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (2-1) and San Diego Padres (2-3) close out a 4-game series Sunday at Petco Park. First pitch is scheduled for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 2-1

San Francisco went 4 for 7 with runners in scoring position in a 9-6 win over San Diego Saturday. Over their 2 wins in this series, the Giants gave gone 9 of 18 in such situations.

The Padres had 3 extra-base hits Saturday. A San Diego club that last year tallied a league-average .413 slugging percentage has banged out 14 extra-base hits over its last 4 games.

Giants at Padres projected starters

RHP Daulton Jefferies vs. RHP Michael King

Jefferies has not pitched in the Majors since 2022; he missed last season recovering from his 2nd Tommy John surgery.

Owns a 5.75 ERA over 14 career games (10 starts)
Pitched 14 innings in spring training, logging a 2.57 ERA with 16 K against 3 BB
Has never faced the Padres

King (4-8, 2.75 ERA with the New York Yankees in 2023) is making his 1st home start with the Padres after being acquired in the Juan Soto trade. Last season, he had a 1.15 WHIP, 2.8 BB/9 and 10.9 K/9 in 104 2/3 innings.

Last outing: Win, 3 1/3 IP, 3 ER, 4 H, 3 BB, 5 K in 15-11 win vs. Los Angeles Dodgers March 21 (in South Korea)
Has faced the Giants once, tossing 1 2/3 innings against them last April 1 (2 R allowed on 4 H and 1 BB; struck out 3)
This game marks his 20th career start; he owns a 3.44 career ERA across 116 games overall

Giants at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:35 a.m. ET.

Moneyline: Giants +115 (bet $100 to win $115) | Padres -135 (bet $135 to win $100)
Run line (RL)/Against the spread (ATS): Giants +1.5 (-175) | Padres -1.5 (+145)
Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Giants at Padres picks and predictions

Prediction

Padres 5, Giants 4

Moneyline

There are too many questions on the Giants side of the ledger, especially with Jefferies getting the nod for the 1st time since May 18, 2022.

King will likely see a hefty contingent of left-handed batters in the San Francisco order, but the former Yankee relief standout has an excellent history against batters of the opposite hand (.656 OPS allowed career, .542 OPSA in 2023).

The Padres went 9-3 at home last September; they are 13-7 across their last 20 home games against San Francisco.

FanDuel Sportsbook has the best value price here: BET THE PADRES (-132).

Run line/Against the spread

PASS: Peg the ML as having the best leverage in this matchup.

Over/Under

The Over has cashed in all 3 games of this series.

Both offenses are clicking so far this season, and there are mound questions on both sides in this series finale. Last September, the Padres got on a roll at home. Over those last 12 games referenced above, they cranked out an .854 OPS while scoring 5.58 runs per game.

San Francisco banged out an .817 OPS in spring training, and batters on both sides get the likely benefit of a significant outward breeze, which is in the forecast. The game could also be in jeopardy due to expected heavy rain.

FanDuel Sportsbook has better leverage: BACK THE OVER 8.5 (-110).

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San Francisco Giants at San Diego Padres odds, picks and predictions

Analyzing Saturday’s San Francisco Giants at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (2-2) welcome the San Francisco Giants (1-1) to Petco Park for the 3rd of a 4-game series Saturday. First pitch is set for 7:15 p.m. ET (FOX). Let’s analyze FanDuel Sportsbook’s lines around the Giants vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1.

The Padres lost their season-opening game 5-2 to the Los Angeles Dodgers but won the following 2, scoring at least 6 in both games. In its 4th game of the season, San Diego lost to the Giants 8-3. It has yet to hold a team to under 4 runs. The Padres finished 3rd in the National League West last season with an 82-80 record. They were 44-37 at home.

The Giants lost to the Padres 6-4 on Opening Day as a slight underdog then took down the Padres 8-3 Friday, closing +124 on the moneyline. The Giants have the league’s 10th-highest payroll, so expectations are high for them this season. San Fran finished last season 79-83 and was 34-47 on the road. They are 1-1 against the spread (ATS) this season and 2-0 O/U.

Giants at Padres projected starters

RHP Jordan Hicks vs. RHP Dylan Cease

Hicks (3-9, 3.29 ERA) made 65 appearances and 0 starts in 2023. He owned a 1.35 WHIP, 4.4 BB/9 and 11.1 K/9 through 65 2/3 IP.

2023 road splits: 2-3, 0.87 ERA (31 IP, 3 ER — 2 HR), 9 BB, 42 K in 31 appearances.
Hasn’t pitched against San Diego since April 7, 2019
Spent last season split between the Cardinals and Blue Jays

Cease (7-9, 4.58 ERA) made 33 starts last season for the White Sox. He finished with a 1.42 WHIP, 4.0 BB/9 and 10.9 K/9 through 177 IP.

2023 home splits: 3-7, 4.20 ERA (94 1/3 IP, 44 ER — 8 HR), 48 BB, 104 K in 17 starts
White Sox were 16-17 in the 33 games Cease started last season
2023 vs. San Francisco: Win, 5 IP, 1 ER (1 HR), 5 BB, 1 H in a 7-3 home victory

Giants at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11 a.m. ET.

Moneyline (ML): Giants +110 (bet $100 to win $110) | Padres -130 (bet $130 to win $100)
Run line (RL)/Against the spread (ATS): Giants +1.5 (-194) | Padres -1.5 (+160)
Over/Under (O/U): 7.5 (O: -112 | U: -108)

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Giants at Padres picks and predictions

Prediction

Padres 5, Giants 3

Moneyline

BET PADRES (-130).

The Giants will likely play most of their game from the bullpen with Hicks transitioning to the rotation. San Fran didn’t have a terrific set or relievers last season, finishing 14th in the MLB in reliever ERA.

San Diego was solid at home last season, ending 44-37. It was also 43-37 following a loss last season. The Padres should have the pitching edge and have tallied at least 6 runs in 2 of their last 3 games.

Take the home side here and back PADRES (-130).

Run line/Against the spread

PASS.

There’s no real value here. The Giants are too expensive to play as a run-line underdog while the Padres are too risky to take as a run-line favorite. Ultimately, the moneyline has the best team-specific value.

Over/Under

LEAN OVER 7.5 (-112).

If there’s one thing both teams have done well this season, it is hit the Over. The Padres are averaging 8 runs per game over their last 3 games and are 3-1 O/U on the season.

The Giants are 2-0 O/U and have scored at least 4 per game while allowing 4.5 per game in their 2 performances this season. Neither team has an ace taking the mound.

With that in mind, expect the offenses to stay hot and take OVER 7.5 (-112).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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