New York Giants at Arizona Cardinals odds, picks and predictions

Analyzing Sunday’s New York Giants at Arizona Cardinals odds and lines, with expert NFL picks and predictions.

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The New York Giants (0-1) are on the road in Week 2 to take on the Arizona Cardinals (0-1) in their 2023 home opener Sunday. Kickoff from State Farm Stadium is 4:05 p.m. ET (FOX). Below, we analyze BetMGM Sportsbook’s lines around the Giants vs. Cardinals odds, and make our expert NFL picks and predictions.

The Giants opened the season by getting shut out 40-0 at home by the Dallas Cowboys. They turned the ball over 3 times (2 interceptions, 1 lost fumble) and QB Daniel Jones was sacked 7 times and fumbled twice (although both were recovered).

The Cardinals lost 20-16 on the road to the Washington Commanders but covered as 7-point underdogs. Arizona had 6 sacks and 3 takeaways but QB Josh Dobbs lost 2 fumbles that resulted in 10 Washington points.

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Giants at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 12:05 p.m. ET.

  • Moneyline (ML): Giants -210 (bet $210 to win $100) | Cardinals +170 (bet $100 to win $170)
  • Against the spread (ATS): Giants -4 (-110) | Cardinals +4 (-110)
  • Over/Under (O/U): 39.5 (O: -110 | U: -110)

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Giants at Cardinals key injuries

Giants

  • LB Azeez Ojulari (hamstring) doubtful
  • WR Wan’Dale Robinson (knee) doubtful
  • OL Andrew Thomas (hamstring) questionable

Cardinals

  • Budda Baker (hamstring) questionable
  • DL L.J. Collier (biceps) out
  • DL Leki Fotu (shoulder) questionable
  • LB Josh Woods (ankle) out

Giants at Cardinals picks and predictions

Prediction

Cardinals 22, Giants 20

Moneyline

The Cardinals got almost nothing offensively in Week 1, netting only 210 total yards (and 60 of those came on 2 plays in their 1st possession), and the defense scored the only touchdown. However, the Giants’ defense isn’t as good as the Commanders’.

The problems of protection that New York had last week should again be a problem against Arizona. The Cards had 6 sacks last week and have sacked Jones 14 times in his 2 career starts vs. them.

BET CARDINALS (+170).

Against the spread

When the line opened at Giants -5.5, this was an easy pick.

The Cardinals proved to be tougher than expectations had them while the Giants — a playoff team last year — looked exceptionally bad in Week 1.

This is a home opener for Arizona with a new coaching staff, so there will be some extra energy in the stadium. There will be plenty of Giants fans as well, but the Cardinals should be able to do a little more offensively than they did in Week 1.

Expect a close game at a minimum and take the Cardinals to cover if you can’t quite take them to win outright.

BET CARDINALS +4 (-110).

Over/Under

Neither team’s game hit the Over in Week 1 but this game’s 39.5-point projected total is low.

The Cardinals and Commanders had 36 total points and Arizona didn’t score an offensive touchdown.

New York’s offense is probably better than Washington’s. New York’s defense isn’t as good as Washington’s, so Arizona should be able to do a little better.

I lean OVER 39.5 (-110).

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San Francisco Giants at St. Louis Cardinals odds, picks and predictions

Analyzing Tuesday’s San Francisco Giants at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

The San Francisco Giants (34-32) and St. Louis Cardinals (27-40) play the 2nd contest of a 3-game set Tuesday at Busch Stadium. First pitch is at 7:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 4-1

The Cardinals’ bullpen handed the Giants Monday’s game by a 4-3 score. St. Louis relievers allowed 2 runs on 5 hits and a walk in the 7th and 8th innings with just 1 punchout. That’s far too many for your setup men. The Cards bullpen has a 1.35 WHIP, which is 21st in MLB.

The Giants allowed runners on 1st and 3rd with 1 out in the 8th inning, but 3B Nolan Arenado popped out to 1st base for a 2nd out. RHP closer Camilo Doval stepped in and walked C Willson Contreras to load the bases before shutting the door the rest of the way for his 17th save. The Giants are 6-4 over their last 10 games and 11-7 against the NL Central.

The Cardinals continue to cycle through different ways to lose each game. They are far too reliant on home runs, and that gets them into bad habits where they can’t score runs in crucial situations. St. Louis is 7-16 in 1-run games and has lost 8 of its last 10 outings.

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Giants at Cardinals projected starters

RHP Alex Cobb vs. RHP Jack Flaherty

Cobb (5-2, 3.01 ERA) makes his 14th start. He has a 1.35 WHIP, 2.3 BB/9 and 8.6 K/9 in 74 2/3 innings.

  • Last 7 starts: 4-1, 3.48 ERA, 1.40 WHIP, 38 K in 41 1/3 IP; allowed 11 of 16 ER in 2 starts
  • 3 career starts vs. St. Louis: 2-0, 0.86 ERA, 0.76 WHIP, 22 K in 21 IP

Flaherty (3-4, 4.15 ERA) makes his 14th start. He has a 1.50 WHIP, 5.2 BB/9 and 9.3 K/9 in 69 1/3 innings.

  • Last start: No-decision, 6 IP, 0 ER, 3 H, 5 BB, 8 K in a 1-0 road win vs. the Texas Rangers Wednesday
  • 4 career starts vs. Giants: 1-1, 3.80 ERA, 0.98 WHIP, 22 K in 21 1/3 IP

Giants at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:32 p.m. ET.

  • Moneyline (ML): Giants -105 (bet $105 to win $100) | Cardinals -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants -1.5 (+155) | Cardinals +1.5 (-190)
  • Over/Under (O/U): 9 (O: +100 | U: -120)

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Giants at Cardinals picks and predictions

Prediction

Giants 4, Cardinals 2

Moneyline

The Cards are favored in this one in part because Flaherty has found something in his mechanics to turn his season around. He must have partially lost that in his last start as he walked 5, but he was able to keep them from scoring. Flaherty’s 40 walks are tied for the most in the NL and 2nd most in MLB.

On the other side, Cobb threw a 6-hit shutout against the Cards in April and has yielded 2 ER over 14 IP in his 2 recent starts against them. The Cards also lost closer RHP Ryan Helsley to a forearm strain in a bullpen that has already been overmatched.

Take the GIANTS (-105).

Run line/Against the spread

The Cards are playing far too many 1-run games to take the Giants here, but the Cards aren’t playing well enough to trust to stay within a run at -190.

PASS.

Instead, I like ALEX COBB OVER 4.5 STRIKEOUTS (-160). He has struck out 5+ in 4 straight starts and 5 of 7.

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Over/Under

Neither club has been an Over team as San Francisco is 3-7 O/U over the last 10 and St. Louis is 3-6-1 O/U over the last 10. This total has been steamed up from 8.5 this morning as the win is blowing out at 13 mph toward right-center.

The Under is 10-0-1 in the Cardinals’ last 11 games following a loss and 5-0-1 in their last 6 against a team over .500. The Under is also 4-1 in the last 5 meetings between these sides.

Take the UNDER 9 (-120).

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San Francisco Giants at St. Louis Cardinals odds, picks and predictions

Analyzing Monday’s San Francisco Giants at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

The San Francisco Giants (33-32) and St. Louis Cardinals (27-39) open up a 3-game set Monday at Busch Stadium. First pitch is at 7:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 3-1

The Giants lost 2 of 3 to the Chicago Cubs over the weekend as they continue to hover around .500. They are 5-5 over their last 10 games and 12-8 over their last 20. San Francisco is in 3rd place in the NL West, 7 games behind the division-leading Arizona Diamondbacks. The Giants are 10-6 against left-handed starters, which they’ll see Monday.

The Cardinals continue to underperform, losing 2 of 3 to the Cincinnati Reds from Friday-Sunday. Bad defense has been the culprit this time, and they’re now 3-7 over the last 10 games. St. Louis still sits just 8 games out of 1st in the NL Central, so it could still turn things around.

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Giants at Cardinals projected starters

RHP Logan Webb vs. LHP Matthew Liberatore

Webb (4-6, 3.09 ERA) makes his 14th start. He has a 1.09 WHIP, 1.8 BB/9 and 9.1 K/9 in 84 1/3 innings.

  • Last 2 starts: 12 1/3 IP, 7 ER, 12 H, 3 BB, 9 K vs. the Baltimore Orioles (June 2) and at the Colorado Rockies (Wednesday)
  • Last 5 starts vs. St. Louis: 2-2, 5.55 ERA, 1.64 WHIP, 19 K in 24 1/3 IP

Liberatore (1-2, 6.00 ERA) makes his 4th start and 5th appearance. He has a 1.60 WHIP, 4.8 BB/9 and 6.6 K/9 in 15 innings.

  • Last start: Loss, 4 IP, 7 ER, 6 H, 2 BB, 2 K in a 6-4 road loss vs. the Texas Rangers Tuesday
  • Has never faced Giants before
  • 2023 splits: 1-0 with a 3.00 ERA in 2 home appearances vs. 0-2 with an 8.00 ERA in 2 road starts

Giants at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:44 a.m. ET.

  • Moneyline (ML): Giants -130 (bet $130 to win $100) | Cardinals +110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Giants -1.5 (+135) | Cardinals +1.5 (-160)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Giants at Cardinals picks and predictions

Prediction

Giants 7, Cardinals 4

Moneyline

Webb’s 5.55 ERA against St. Louis is heavily skewed by a 7 ER shelling in a 2019 start, but he has been pretty good the last 2 times out against them. The Cards are just snake-bitten, and something isn’t clicking. They weren’t even competitive at times in the 4-game series in San Francisco in late April. Liberatore has also been bad in his last 2 starts, allowing 9 ER in as many innings.

I’ll take the GIANTS (-130).

Run line/Against the spread

The Cards are just 28-38 on the RL this season and an abysmal 11-20 at home. They can’t be trusted to stay within a run, especially at -160.

PASS.

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Over/Under

It’s expected to be a fair 73-degree evening with a 9-mph wind pushing toward the right field foul pole. Both of these teams live and die by the home run, and it’ll really have to be tagged to get out Monday. They combined for 9 runs in 2 of the 4 games in San Francisco and 5 of the last 10 against one another.

This is really dicey, so go easy, but with the way the Cards’ pitching and defense have been, I’ll LEAN OVER 8 (-115)

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San Francisco Giants at St. Louis Cardinals odds, picks and predictions

Analyzing Sunday’s San Francisco Giants at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The San Francisco Giants (20-13) play the third and final game of their 3-game road set against the St. Louis Cardinals (18-15) on ESPN Sunday Night Baseball to determine who earns the series win. First pitch is 7:08 p.m. ET at Busch Stadium. Let’s analyze Tipico Sportsbook‘s lines around the Giants vs. Cardinals odds with MLB picks and predictions.

Season series: Tied 3-3. This is the final game between the two teams in the regular season.

The Giants had a 6-game winning streak snapped Saturday with a 4-0 loss. They have been streaky. Right before their 6-game winning streak, they lost 5 in a row and 7 of 8. Before that, they won 5 straight.

The Cardinals, with Saturday’s 4-0 victory, won for only the second time in their last 7 games. They split 4 games against the Giants in San Francisco last week and can clinch a season series win with a victory in this finale.

Giants at Cardinals projected starters

LHP Carlos Rodon vs. RHP Adam Wainwright

Rodon (4-1, 1.80 ERA) makes his 7th start. He has a 1.21 WHIP, 3.1 BB/9 and league-leading 13.6 K/9 through 35 IP.

  • Rodon has not yet allowed a home run this season.
  • He has not allowed more than 2 runs in any start this season. He has lasted 6 innings in each of his last 3 appearances.

Wainwright (3-3, 3.18 ERA) makes his 7th start. He has a 1.29 WHIP, 3.4 BB/9 and 7.4 K/9 through 34 IP.

  • The 17-year veteran is coming off his best start of the season. He pitched 7 shutout innings, allowing only 1 hit in a 10-0 victory at the Kansas City Royals May 4.
  • He is 8-8 in 19 career regular-season appearances (17 starts) against the Giants with a 3.34 ERA.

Giants at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 4:07 p.m. ET.

  • Money line (ML): Giants -140 (bet $140 to win $100) | Cardinals +115 (bet $100 to win $115)
  • Run line (RL)/Against the spread (ATS): Giants -1.5 (+130) | Cardinals +1.5 (-160)
  • Over/Under (O/U): 6.5 (O: -140 | U: +112)

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Giants at Cardinals picks and predictions

Prediction

Giants 4, Cardinals 2

Money line

Rodon has been so good this season. He has allowed 2 or fewer runs in every start this season and has lasted at least 5 innings every time.

The Cardinals, other than two single-game wins at home against Kansas City, have not won a home series this season.

These are two fantastic pitchers battling each other. Wainwright was fantastic in his last outing.

But I’m going to “lean” with the advantage to Rodon.

The Cardinals have a slight edge in bullpen ERA (3.17 vs. 3.46 for the Giants), but I LEAN GIANTS (-140).

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Run line/Against the spread

Fifteen of the Giants’ last 16 victories have been by at least 2 runs. All 4 of their wins with Rodon starts have been by at least 2 runs.

Six of the Cardinals’ last 7 losses have been by at least 2 runs.

They are 9-8 at home, while the Giants are 9-6 on the road.

Take GIANTS -1.5 (+130).

Over/Under

Can you say pitchers’ duel? That is more or less what I expect in this matchup.

The Cardinals have scored 3 or fewer runs in 4 of their last 6 games.

Half of both Rodon’s and Wainwright’s 6 starts have had 6 runs or fewer.

I LEAN UNDER 6.5 (+112).

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San Francisco Giants at St. Louis Cardinals odds, picks and prediction

Analyzing Sunday’s San Francisco Giants at St. Louis Cardinals odds and lines, with MLB picks and predictions.

The San Francisco Giants (58-33) conclude their three-game set at Busch Stadium with the St. Louis Cardinals (45-47) Sunday. First pitch is scheduled for 2:15 p.m. ET. Let’s analyze BetMGM Sportsbook‘s lines around the Giants vs. Cardinals odds with MLB picks and predictions.

St. Louis picked up the win Saturday, 3-1, evening the set after San Francisco won the first meeting Friday, 7-2.

Season series: Cardinals lead 3-2.

RHP Johnny Cueto is San Francisco’s projected starter. Cueto is 6-5 with a 4.15 ERA (78 IP, 36 ER), 1.33 WHIP, 1.7 BB/9 and 7.5 K/9 over 14 starts.

  • Last outing: Loss, 6-5, with 6 IP, 4 ER, 9 H, 1 BB and 7 K July 6 against St. Louis.
  • vs. Cardinals on the current roster: 177 at-bats with a .254/.318/.469 slash line, 38/12 K/BB, 9 HR and 27 RBIs.

LHP Wade LeBlanc takes the hill for the Cardinals. LeBlanc is 0-2 with a 4.78 ERA (26 1/3 IP, 14 ER), 1.52 WHIP, 3.1 BB/9 and 5.5 K/9 over four starts and nine relief appearances.

  • Last outing: Loss, 10-5, with 3 IP, 3 ER, 5 H, 3 BB and 1 K July 9 at the Chicago Cubs.
  • LeBlanc’s pitching peripherals this season are dreadful; he grades in the 21st percentile or worse in hard-hit rate, expected wOBA, expected slugging percentage, K% and whiff rate.

MLB betting offers/promotions

BetMGM Sportsbook offers available in CO, IA, IN, MI, NJ, PA, TN, VA, WV and Washington D.C. New customer offers, terms and conditions apply.

  • Bet just $1 on either team’s money line, WIN $100 (in free bets) if either team hits a home run during the game. Bet now!
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Giants at Cardinals odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 9:19 a.m. ET.

  • Money line: Giants -130 (bet $130 to win $100) | Cardinals +105 (bet $100 to win $105)
  • Against the spread/ATS: Giants -1.5 (+125) | Cardinals +1.5 (-155)
  • Over/Under: 8.5 (O: -110 | U: -110)

Prediction

Giants 4, Cardinals 3

Money line (ML)

GIMME the GIANTS (-130) for 1 unit because they have an edge in both starting and relief pitching, hit lefties better than the Cardinals hit righties and there’s been “sharp” line movement towards San Francisco.

For example, the Giants hitters rank 11th or better vs. left-handed pitching in advanced hitting metrics such as wRC+, wOBA, BB/K and OPS while the Cardinals batters sit in the bottom 10 vs. righties in each of those stats.

Furthermore, San Francisco’s bullpen is pretty mediocre but St. Louis’s ranks dead last in xFIP, SIERA and K-BB%.

Lastly, the market is hammering San Francisco’s money line, which has caused oddsmakers to move the Giants’ price up 20 cents on the dollar from the opener because of their liability against the pro-San Francisco action.

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Run line/Against the spread (ATS)

PASS because the Cardinals -1.5 (+125) isn’t a big enough payout for me especially if we are getting to the party late on San Francisco’s money line.

Over/Under (O/U)

Slight “LEAN” to the UNDER 8.5 (-110) for a one-third unit – if at all – because I prefer San Francisco’s money line more than the total.

However, there’s a suspect “line freeze” in the betting market with more than 80% of the cash wagered on the total being on the Over (according to Pregame.com) but the line hasn’t budged.

Typically when we see one-sided action in the betting market then the House increases the price of the more popular side, so the total not moving despite heavy action on the Over is alarming.

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San Francisco Giants at St. Louis Cardinals odds, picks and prediction

Analyzing Friday’s San Francisco Giants at St. Louis Cardinals odds and lines, with MLB picks and predictions.

The San Francisco Giants (57-32) visit the St. Louis Cardinals (44-46) Friday for the first of their three-game set at Busch Stadium with an 8:15 p.m. ET first pitch. Let’s analyze BetMGM Sportsbook‘s lines around the Giants vs. Cardinals odds with MLB picks and predictions.

Season series: Cardinals 2-1.

RHP Kevin Gausman is on the mound for the Giants. Gausman is 9-3 with a 1.73 ERA (114 2/3 IP, 22 ER), 0.82 WHIP, 2.4 BB/9 and 10.4 K/9 across 18 starts.

  • Last outing: Win, 3-1, with 6 IP, 1 ER, 4 H, 3 BB and 9 K vs. the Washington Nationals Sunday.
  • Gausman took a loss earlier this month vs. the Cardinals (July 5) with 7 IP, 2 ER, 3 H, 2 BB and 8 K in San Francisco’s 5-3 defeat.
    • vs. Cardinals on the current roster: 59 at-bats with a .237/.328/.441 slash line, 17/8 K/BB, 3 HR and 7 RBIs.

RHP Adam Wainwright takes the hill for the Cardinals. Wainwright is 7-5 with a 3.58 ERA (105 2/3 IP, 42 ER), 1.16 WHIP, 2.6 BB/9 and 8.4 K/9 over 17 starts.

  • Last outing: Win, 6-5, with 5 IP, 3 ER, 7 H, 4 BB and 3 K at the Giants July 6.
  • vs. Giants on the current roster: 133 at-bats with a .241/.304/.323 slash line, 18/11 K/BB, 1 HR and 13 RBIs.

MLB betting offers/promotions

BetMGM Sportsbook offers available in CO, IA, IN, MI, NJ, PA, TN, VA, WV and Washington D.C. New customer offers, terms and conditions apply.

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Giants at Cardinals odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 2:35 p.m. ET.

  • Money line: Giants -135 (bet $135 to win $100) | Cardinals +110 (bet $100 to win $110)
  • Against the spread/ATS: Giants -1.5 (+125) | Cardinals +1.5 (-155)
  • Over/Under: 7.5 (O: -105 | U: -115)

Prediction

Cardinals 3, Giants 2

Money line (ML)

PASS with a slight “lean” to the Cardinals (+120) First 5 Innings since St. Louis’ bullpen is terrible.

Since Wainwright has better pitching peripherals vs. current San Francisco batters is much better than Gausman’s against active Cardinals hitters, St. Louis is my preferred side.

Also, the Cardinals are 23-18 at home this season and already took two of three against the Giants in San Francisco earlier this month.

However, most of the baseball community has banked on regression from San Francisco that we haven’t seen yet. Plus Gausman has been dominant this season, so I’d rather take St. Louis’ First 5 Innings run line.

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Run line/Against the spread (ATS)

Quietly, Wainwright has re-established himself as the clear ace of the St. Louis rotation since starting RHP Jack Flaherty has gone to the IL.

And despite Wainwright picking up a win in his last start against the Giants, it was his first non-quality start since May 29.

Over that span, Wainwright is 4-1 with a 2.70 ERA (46 IP, 14 ER), 12 BB, 42 K and three home runs allowed in seven starts.

Furthermore, Wainwright has pitched much better at home this season. He is 4-3 in 10 starts at Busch Stadium this season with a 2.55 ERA (5.35 road ERA), 0.97 WHIP (1.47 road WHIP) and a 4.1 K/BB rate (2.3 K/BB rate on the road).

“LEAN” to the CARDINALS +0.5 (-125) FIRST 5 INNINGS for a half unit since St. Louis’ bullpen ranks dead-last in xFIP and K-BB%, and I want to split my unit wager on this game with the Under.

Over/Under (O/U)

“LEAN” to the UNDER 7.5 (-115) for a half unit because both teams have their aces on the mound Friday, the Giants are 8-9 O/U when Gausman starts, and the Cardinals are 6-11 O/U when Wainwright is on the bump.

Moreover, the Giants are 20-25-1 O/U on the road, and the Cardinals are 16-21-3 O/U at home this season.

That being said, the market is hammering the Under, and this total is “sharp” so there isn’t a ton of value in betting it.

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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