San Diego Padres at Pittsburgh Pirates odds, picks and predictions

Analyzing Tuesday’s San Diego Padres at Pittsburgh Pirates odds and lines, with MLB expert picks, predictions and best bets.

The San Diego Padres (37-41) open a 6-game road trip on Tuesday with the 1st game of a 3-game series against the Pittsburgh Pirates (35-42). First pitch from PNC Park is at 7:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Pirates odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 4 of 6 meetings in 2022

The Padres lost the final 2 games of a 3-game series at home against the Washington Nationals, including an 8-3 defeat in the series finale on Sunday. They have lost 5 out of their last 7 games.

The Pirates have lost 12 of their last 13 games. They snapped a 10-game losing streak beating the Miami Marlins on Friday, but lost 3 of 4 games in the series, including the last 2 games. They were shut out 2-0 on Sunday.

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Padres at Pirates projected starters

RHP Yu Darvish vs. LHP Rich Hill

Darvish (5-6, 4.84 ERA) makes his 15th start. He has a 1.23 WHIP, 2.8 BB/9 and 9.6 K/9 in 80 innings.

  • Last start: Loss, 6 IP, 4 ER, 7 H, 2 BB, 6 K in 4-2 road loss to San Francisco Giants last Wednesday
  • Is 1-2 with 7.71 ERA in last 3 starts

Hill (6-7, 4.34 ERA) makes his 16th start. He has a 1.37 WHIP, 3.4 BB/9 and 8.2 K/9 in 83 innings.

  • Last start: Loss, 5 2/3 IP, 5 R (3 ER), 4 H, 2 BB, 4 K in 8-3 home loss to Chicago Cubs last Wednesday
  • Is 2-4 with 5.05 ERA in last 6 starts

Padres at Pirates odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:45 a.m. ET.

  • Moneyline (ML): Padres -190 (bet $190 to win $100) | Pirates +155 (bet $100 to win $155)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (-115) | Pirates +1.5 (-105)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Padres at Pirates picks and predictions

Prediction

Padres 6, Pirates 4

Moneyline

The Pirates only have 1 win in their last 13 games and only 3 in their last 18. They have not scored more than 4 runs in their last 11 games and have been shut out 4 times. The Padres have lost 5 of their last 7, but are 9-9 in their last 18. However betting the Padres on the moneyline isn’t worth the action, having to wager nearly twice what you can win.

PASS.

Run line/Against the spread

The Pirates have covered the spread only twice in the last 9 games and only 3 times in their last 15. Seven of their last 8 losses have been by 2 or more runs. Five of the Padres’ last 6 wins have been by at least 2 runs.

BET PADRES -1.5 (-115).

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Over/Under

The Pirates have struggled on offense, scoring only 15 runs in their last 9 games. But with both pitchers with ERAs over 5.00 over their last several starts, there is bound to be some offense early. The Padres have had 3 of their last 4 games finish with totals over 9 runs.

BET OVER 9 (-105).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Thursday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (35-39) and San Francisco Giants (42-32) meet Thursday in the finale of a 4-game NL West series. First pitch from Oracle Stadium is slated for 3:45 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 3-2

San Diego is looking to avoid being swept. The Friars have only been swept in 1 other series this season, May 12-14 at the Los Angeles Dodgers.

The Giants are orange-hot. They head into Thursday afternoon looking for their 11th consecutive victory. Over its 10 straight wins, San Francisco has averaged 8 runs per game on a high-contact .859 OPS. Prior to this series, the Giants had gone just 2-6 over 8 home games from May 30-June 11.

San Francisco is 2nd in the NL West, 2 1/2 games behind the Arizona Diamondbacks and 7 games ahead of the 4th-place Padres.

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Padres at Giants projected starters

LHP Blake Snell vs. LHP Alex Wood

Snell (3-6, 3.48 ERA) makes his 15th start. He has a 1.29 WHIP, 4.8 BB/9 and 11.2 K/9 in 75 innings.

  • Owns an 18.9% swinging-strike rate over his last 3 starts and is facing a Giants offense that has filed a 25.7 whiff percentage against southpaws
  • Owns a 3.15 ERA on the road over the last 2 years

Wood (2-1, 4.11 ERA) is making his 9th start. He has a 1.46 WHIP, 4.1 BB/9 and 8.7 K/9 in 35 innings across 9 games (8 starts).

  • Owns a 3.70 ERA, 1.23 WHIP over 249 career games
  • Has an 8.10 ERA over his last 3 home starts
  • Has gone past 5 innings just once this season

Padres at Giants odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:20 a.m. ET.

  • Moneyline: Padres -130 (bet $130 to win $100) | Giants +110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+126) | Giants +1.5 (-152)
  • Over/Under (O/U): 8 (O: -120 | U: -102)

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Padres at Giants picks and predictions

Prediction

Padres 5, Giants 4

Moneyline

The Padres lost Wednesday’s game 4-2; they are 6-0 across their last 6 games after scoring 2-or-less runs the prior game.

San Diego is 0-6 in extra innings and 5-13 in 1-run games. The Friars are deserving of a better record than where they stand. Also, figure their schedule as being tougher than that of the Giants so far.

The lefty-lefty match-up favors the Padres; the better side of their platoon splits have them owning a top-10 OPS (.768) against lefties.

Swimming upstream against a San Francisco win streak is not ideal. Some bettors may want to avoid this play or dial down the unit percentage, but PADRES (-130) has value.

Run line/Against the spread

The Over has a lean, but the return here on San Diego is not great. PASS.

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Over/Under

The Over is 9-4 in the last 13 series meetings.

The Friars average just 3.70 RPG at home, but on the road that figure jumps to 4.65.

An outward breeze is in the forecast, and there is some lean against both starters and the Padre bullpen. Both bullpens have some availability concerns at the back end.

BACK THE OVER 8 (-120). Consider a partial-unit play unless the price drops to -115 or better.

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Wednesday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (35-38) and San Francisco Giants (41-32) meet Wednesday for the 3rd game of a 4-game NL West set. First pitch from Oracle Stadium is slated for 9:45 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 2-2

San Diego has dropped the 1st 2 games of this series, and the Padres are just 2-4 over their last 6 games. They sit 4th in  the NL West, 8 1/2 game out of 1st place.

The Giants head into Wednesday night looking for their 10th consecutive victory. San Francisco’s offense has banged out an .877 OPS over that span. The Giants have outscored opponents 76-29 over the 9 straight wins and have surged into 2nd place in the NL West, 2 1/2 games behind the Arizona Diamondbacks.

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Padres at Giants projected starters

RHP Yu Darvish vs. RHP Ryan Walker

Darvish (5-5, 4.74 ERA) makes his 14th start of the season. He owns a 1.20 WHIP, 2.8 BB/9 and 9.6 K/9 in 74 innings.

  • Has yielded 10 R over his last 10 1/3 IP and owns a 6.75 ERA in his last 7 starts
  • Has a 9.75 ERA over his last 5 starts against San Francisco

Walker (2-0, 1.65 ERA) is tabbed for his 2nd start. He has a 1.16 WHIP, 1.7 BB/9 and 8.3 K/9 in 16 1/3 IP across 12 games (1 start).

  • The 27-year-old rookie has pitched 20 1/3 IP in Triple-A this season (0.89 ERA, 0.85 WHIP)
  • Likely to serve as an opener with LHP Sean Manaea (2-3, 5.84 ERA, 1.38 WHIP) logging bulk innings behind him

Padres at Giants odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:45 a.m. ET.

  • Moneyline: Padres -124 (bet $124 to win $100) | Giants +106 (bet $100 to win $106)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+128) | Giants +1.5 (-154)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Padres at Giants picks and predictions

Prediction

Padres 5, Giants 4

Moneyline

The Padres are 9-3 in the last 12 series meetings and are 6-2 in the last 8 games in San Francisco.

San Diego is 0-6 in extra innings and 5-12 in 1-run games. The Friars are deserving of a better record than where they stand. Also, peg their schedule as being tougher than the Giants’ so far.

San Diego batters own a .968 OPS against Manaea, and their platoon numbers favor at-bats against southpaws.

TAKE THE PADRES (-124).

Run line/Against the spread

The Over has a lean, and that makes the Run line favorite worth looking into. But we should want more return here. PASS.

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Over/Under

The Friars average just 3.70 RPG at home, but on the road that figure jumps to 4.72.

A stiff breeze blowing outward is in the forecast for Wednesday’s game. With the way the Giants are hitting and the way the Padres have pounded Manaea in the past, the lean is toward the Over.

BACK THE OVER 8 (-115).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (35-37) and San Francisco Giants (40-32) meet Tuesday to tangle in the 2nd game of a 4-game set. First pitch from Oracle Stadium is slated for 9:45 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 2-1

San Diego lost Monday’s series opener 7-4 in 10 innings. The 7 runs allowed marked just the 2nd time since June 5 the Friars allowed more than 6 in a single game. San Diego ranks 4th in MLB with a 3.75 ERA on the season.

The Giants have scored 6 runs or more in 6 straight games and have won 8 straight overall. San Francisco’s offense has authored a robust .889 OPS over that span.

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Padres at Giants projected starters

RHP Seth Lugo vs. RHP Anthony DeSclafani

Lugo (3-3, 4.10 ERA) is lined up for his 9th start. He’s posted a 1.37 WHIP, 2.4 BB/9 and 8.2 K/9 through 41 2/3 IP.

  • Comes off the IL (calf) without a rehab assignment to the minors after having last pitched on May 16
  • Owns a 3.52 and 1.18 WHIP ERA over 283 career games (46 starts)

DeSclafani (4-6, 4.31 ERA) makes his 15th start. He has a 1.19 WHIP, 1.9 BB/9 and 6.8 K/9 through 79 1/3 IP.

  • Got off to a hot start but has struggled over his last 8 outings (6.31 ERA); has allowed 5 ER in 2 of his last 3 starts
  • Current Padres own an aggregate .858 OPS against him

Padres at Giants odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:50 a.m. ET.

  • Moneyline: Padres -106 (bet $106 to win $100) | Giants -110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+158) | Giants +1.5 (-192)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Padres at Giants picks and predictions

Prediction

Padres 6, Giants 4

Moneyline

The Padres are 9-2 in the last 11 series meetings and are 6-1 in the last 7 games in San Francisco.

Lugo will see a lot of lefty bats in the San Francisco lineup. He’s been hurt from that side so far this season (.830 OPS) but alongside a .383 batting average on balls in play. For his career, he’s held lefty bats to a .670 OPS.

San Diego is 0-6 in extra innings and 5-12 in 1-run games. They are deserving of a better record than where they stand. Peg their schedule as being tougher than the Giants’ so far.

TAKE THE PADRES (-106).

Run line/Against the spread

If the price stays at Padres -1.5 (+158) or better, this play can be mixed with the above (say, a half unit on the moneyline and a half on the run line) for some extra leverage.

BACK THE PADRES -1.5 (+158).

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Over/Under

The Over is 4-1 in the last 5 series meetings in San Francisco.

The Friars average just 3.70 RPG at home, but on the road that figure jumps to 4.77.

A hefty wind blowing out is in the forecast for Tuesday’s game. With the way the Giants are hitting and the way the Padres have pounded DeSclafani in the past, this one could be near the number by the 7th-inning stretch.

BACK THE OVER 8.5 (-115).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Monday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

The San Diego Padres (35-36) and San Francisco Giants (39-32) meet Monday to kick off a 4-game series. First pitch from Oracle Park is set for 9:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 2-0

The Padres won 5-4 as -151 home favorites Sunday vs. the Tampa Bay Rays. San Diego scored 3 runs in the 3rd inning and 1 run in both the 4th and 5th innings to take a 5-2 that it never gave up despite giving up 2 runs in the 8th frame. San Diego has won back-to-back games on Saturday and Sunday after suffering back-to-back losses on Thursday and Friday.

San Francisco won 7-3 as a +104 road underdog Sunday vs. the Los Angeles Dodgers. The Giants held a 3-2 lead heading into the top of the 6th before they exploded for 4 runs to seal the game and complete the 3-0 sweep of the Dodgers. San Francisco has won 7 straight games heading into this series to move into 2nd place in the NL West, 3 1/2 games back of the division-leading Arizona Diamondbacks.

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Padres at Giants projected starters

RHP Michael Wacha vs. RHP Ryan Walker

Wacha (7-2, 2.89 ERA) makes his 14th start. He has a 1.06 WHIP, 2.5 BB/9 and 8.3 K/9 through 74 2/3 IP.

  • Last outing: Win, 6 2/3 IP, 0 ER, 4 H, 1 BB, 5 K in a 5-0 home victory Wednesday vs. Cleveland Guardians
  • Career vs. San Francisco: 2-0 with a 1.42 ERA (38 IP, 6 ER), 31 H, 32 K, 1.11 WHIP across 7 starts

Walker (2-0, 1.23 ERA) makes his 1st start and 12th appearance. He has a 1.02 WHIP, 1.2 BB/9 and 9.2 K/9 through 14 2/3 IP.

  • Last outing: No-decision, 1 1/3 IP, 0 ER, 2 H, 0 BB, 0 K as a reliever in a 7-5 road win Friday vs. Los Angeles Dodgers
  • First career start vs. San Diego

Padres at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7 a.m. ET.

  • Moneyline (ML): Padres -110 (bet $110 to win $100) | Giants -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+145) | Giants +1.5 (-175)
  • Over/Under (O/U): 8.5 (O: -120 | U: +100)

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Padres at Giants picks and predictions

Prediction

Padres 5, Giants 4

Moneyline

LEAN PADRES (-110).

The Giants are the hotter team but have not yet proven they can beat the Padres this year, losing both previous meetings. San Francisco is 18-17 at home this season whereas the Padres are 16-16 on the road, meaning neither team has a whopping advantage here. However, San Diego is 9-1 in the last 10 meetings with San Francisco, earning it the lean here.

Run line/Against the spread

PASS.

I could really see this bet going either way and while I am confident in the Padres winning, I’m not confident in them winning by 2 or more runs. However, the Giants at +1.5 (-175) is not worth the juice as they are far too heavy of a favorite in the run line for this game.

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Over/Under

BET OVER 8.5 (-120).

The Over is 5-0 in San Francisco’s last 5 games and 6-1 in its last 7 games overall. The Over is also 5-1 in the last 6 matchups between these clubs and 8-2 in their last 10 meetings.

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Tampa Bay Rays at San Diego Padres odds, picks and predictions

Analyzing Sunday’s Tampa Bay Rays at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

The Tampa Bay Rays (51-23) and San Diego Padres (34-36) wrap up a 3-game set Sunday at Petco Park. First pitch is scheduled for 4:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Rays vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

The Rays lost 2-0 as +105 underdogs at the Padres Saturday. Tampa Bay has won 3 of 4 and has a 6-game lead in the AL East.

The Padres closed as -114 favorites in Saturday’s win. San Diego avoided its 3rd straight loss and is 4th in the NL West, 8.5 games back of the division-leading Arizona Diamondbacks.

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Rays at Padres projected starters

RHP Yonny Chirinos vs. RHP Joe Musgrove

Chirinos (3-1, 2.35 ERA) makes his 3rd start and 10th appearance. He has a 0.94 WHIP, 2.8 BB/9 and 4.0 K/9 in 38 1/3 innings.

  • Last outing: No-decision, 3 2/3 IP, 2 H, 1 BB, 2 K as a reliever in a 2-1 loss at Oakland Athletics Tuesday
  • First career start vs. Padres

Musgrove (4-2, 4.37 ERA) makes his 10th start. He has a 1.33 WHIP, 2.7 BB/9 and 8.9 K/9 in 47 1/3 innings.

  • Last start: Win, 6 IP, 3 ER, 7 H, 1 BB, 5 K in a 6-3 win vs. Cleveland Guardians Tuesday
  • Career vs. Rays: 0-0, 4.00 ERA (9 IP, 4 ER), 7 H, 1 HR, 2 BB, 8 K in 1 start and 1 relief appearance

Rays at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:54 a.m. ET.

  • Moneyline (ML): Rays +120 (bet $100 to win $120) | Padres -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Rays +1.5 (-160) | Padres -1.5 (+135)
  • Over/Under (O/U): 8.5 (O: -120 | U: +100)

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Rays at Padres picks and predictions

Prediction

Padres 4, Rays 3

Moneyline

San Diego is 5-0 in its last 5 games after scoring 2 or fewer runs in its previous game. Tampa Bay is 1-4 in its last 4 interleague road games vs. right-handed starters and Musgrove has given up 3 runs or fewer in 4 straight starts.

BET PADRES (-145).

Run line/Against the spread

Two of Tampa Bay’s last 3 losses have been by just 1 run. Rays +1.5 (-160) will probably hit, but there’s no need to pay the higher price on the run line when Padres ML is the better play. Bet San Diego ML and/or the total instead.

PASS.

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Over/Under

The Under is 4-0-1 in Tampa Bay’s last 5 interleague games and 7-1-1 in its last 9 on the road.

The Under has gone 19-6-1 in San Diego’s last 26 home games and should hit again Sunday as Musgrove (2.12 ERA in June) continues to string together good starts.

BET UNDER 8.5 (+100).

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Tampa Bay Rays at San Diego Padres odds, picks and predictions

Analyzing Saturday’s Tampa Bay Rays at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

The Tampa Bay Rays (51-22) and San Diego Padres (33-36) meet Saturday for game 2 of a 3-game series. First pitch from Petco Park is set for 7:15 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s lines around the Rays vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Rays lead 1-0

Tampa Bay won 6-2 as +106 road underdogs Friday. Most of this game was all Tampa, as it scored all 6 of its runs before the end of the 5th inning, including 4 runs in that inning alone. The Padres tried to make a late-game push to get on the board but the 6-0 lead the Rays had was simply too much to overcome.

The Rays have now won 3 straight after previously dropping back-to-back games vs. Oakland. The Rays sit at a 20-15 road record on the season, with road losses accounting for all but 7 of their losses on the season thus far.

The Padres are now 2-3 in their last 5 overall and have lost back-to-back home games. San Diego sits at 17-20 at home this season, continuing its home struggles with Friday’s loss.

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Rays at Padres projected starters

RHP Zach Eflin vs. LHP Blake Snell

Eflin (8-2, 3.28 ERA) makes his 13th start. He has a 1.00 WHIP, 1.4 BB/9 and 9.1 K/9 through 71 1/3 IP.

  • Last outing: Loss, 4 2/3 IP, 4 ER, 5 H, 2 BB, 6 K in a 4-3 road loss Monday vs. Oakland Athletics
  • Career vs. San Diego: 2-2 with a 3.38 ERA (26 2/3 IP, 10 ER), 24 H, 20 K, and a 1.16 WHIP across 5 starts

Snell (2-6, 3.78 ERA) makes his 14th start. He has a 1.33 WHIP, 4.8 BB/9 and 10.6 K/9 through 69 IP.

  • Last outing: No-decision, 7 IP, 1 ER, 3 H, 0 BB, 12 K in a 5-4 road loss Sunday vs. Colorado Rockies
  • First career start vs. Tampa Bay

Rays at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:49 a.m. ET.

  • Moneyline (ML): Rays -115 (bet $115 to win $100) | Padres -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Rays -1.5 (+145) | Padres +1.5 (-175)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Rays at Padres picks and predictions

Prediction

Rays 5, Padres 2

Moneyline

BET RAYS (-115). 

Tampa Bay has dominated San Diego lately and with the Padres’ home struggles this season, the Rays are an even safer bet. The Rays are the hotter team and are better on the road than the Padres are at home. The Rays are 9-1 in the last 10 meetings overall and 3-1 in the last 4 meetings in San Diego. The Rays also have the SP advantage here.

Run line/Against the spread

PASS.

This line could truly go either way and I’m not a fan of wagering such a heavy bet on the Padres at +1.5 (-175) considering their home woes and the fact that only 1 of the last 10 meetings has come to a 1-run margin.

If you believe in the Rays at -1.5 (+145) you could place a small wager on that bet, but the moneyline and O/U are both safer.

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Over/Under

LEAN UNDER 8 (-105). 

For San Diego, the Under is 6-0 in its last 6 Saturday games and 6-0-1 in its last 7 interleague home games vs. a team with a winning record. For Snell, the Under is 5-0 in his last 5 starts vs. a team with a winning record.

For Tampa Bay, the Under is 4-0-1 in its last 5 interleague road games and 5-4-1 in its last 10 games overall. For Eflin, the Under is 4-0 in his last 4 starts vs. a team with a losing record, all per covers.com.

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Tampa Bay Rays at San Diego Padres odds, picks and predictions

Analyzing Friday’s Tampa Bay Rays at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

The Tampa Bay Rays (50-22) continue their 7-game road trip with 3 games against the San Diego Padres (33-35). First pitch in Friday’s opener from Petco Park is 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Rays v s. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since 2019 when Rays won 2 of 3 games

The Rays split a 4-game series to open their road trip against the Oakland A’s. They won the final 2 games of the series to gain the series split. They have won 10 of their last 13 games.

The Padres have won 5 of their last 7 games and, while coming off an 8-6 loss to the Cleveland Guardians Thursday at home, they won the series 2-1.

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Rays at Padres projected starters

LHP Shane McClanahan vs. RHP Yu Darvish

McClanahan (10-1, 2.18 ERA) makes his 15th start. He has a 1.11 WHIP, 3.3 BB/9 and 10.0 K/9 in 82 2/3 innings.

  • Last start: Win, 7 IP, 3 ER, 4 H, 1 BB, 5 K in 7-3 home win over Texas Rangers on Sunday
  • Has had quality starts (6+ IP, 3 or fewer ER) in 10 of 14 outings

Darvish (5-4, 4.30 ERA) makes his 13th start. He has a 1.16 WHIP, 2.9 BB/9 and 9.7 K/9 in 69 innings.

  • Last start: Win, 5 1/3 IP, 4 ER, 5 H, 4 BB, 6 K in 9-6 road win over Colorado Rockies
  • Is 3-2 with 6.15 ERA over last 5 starts (28 1/3 IP)

Rays at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:50 a.m. ET.

  • Moneyline (ML): Rays -110 (bet $110 to win $100) | Padres -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Rays -1.5 (+150) | Padres +1.5 (-185)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Rays at Padres picks and predictions

Prediction

Rays 6, Padres 3

Moneyline

The Rays have the best record in all of baseball and have won 10 of their last 13. They are 19-15 on the road while the Padres are 17-19 at home.

McClanahan leads the majors in wins and ERA and Tampa has lost only twice this season when he has started.

Betting the Rays to win at -110 is a fine bet. But there is more money to be made on the run line and also plenty of reasons to bet that.

PASS.

Run line/Against the spread

The Rays are 40-22 ATS on the season, while the Padres are 34-34 ATS. Eight of their last 10 wins have been by at least 2 runs. Ten of their 12 wins with McClanahan on the mound have been by 2 or more runs.

BET RAYS -1.5 (+150).

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Over/Under

Four of the Rays’ last 7 games have had 9 or more total runs. Eight of McClanahan’s 14 starts have had totals of 9 or more runs. Five of the Padres’ last 7 games have had 9 or more total runs.

BET OVER 8 (-105).

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Cleveland Guardians at San Diego Padres odds, picks and predictions

Analyzing Thursday’s Cleveland Guardians at San Diego Padres odds and lines, with MLB expert picks and predictions.

The Cleveland Guardians (31-36) and San Diego Padres (33-34) meet Thursday in the finale of a 3-game set. First pitch at Petco Park is slated for 8:40 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Guardians vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: San Diego leads 2-0

In a 14-game stretch prior to this series, Cleveland had scored 5.43 RPG while banging out a robust .811 OPS. However, in this series that has been San Diego wins of 5-0 Wednesday and 6-3 Tuesday, the Guardians have scored just 3 runs and only have 2 extra-base hits.

San Diego won 2 of 3 games at the Colorado Rockies over the weekend and is 5-1 over its last 6 games. The Padres have hit 13 home runs over that stretch, including 4 round-trippers in Wednesday’s victory.

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Guardians at Padres projected starters

LHP Logan Allen vs. LHP Ryan Weathers

Allen (3-2, 3.31 ERA) makes his 10th start of the season. He has registered a 1.39 WHIP, 2.6 BB/9 and 8.9 K/9 through 51 2/3 IP.

  • A 24-year-old rookie who coughed up a career-high 5 runs in his last start
  • Owns a 1.90 ERA and 1.18 WHIP in 4 outings away from home

Weathers (1-4, 4.93 ERA) makes his 9th start and 11th appearance. He has a 1.49 WHIP, 3.5 BB/9 and 5.9 K/9 through 38 1/3 IP.

  • Is used as a short-inning starter: has thrown just 8 2/3 innings over his last 3 starts
  • Owns a 6.06 career ERA at Petco Park across 12 starts and 6 relief appearances

Guardians at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:38 a.m. ET.

  • Moneyline: Guardians +110 (bet $100 to win $110) | Padres -130 (bet $130 to win $100)
  • Run line (RL)/Against the spread (ATS): Guardians +1.5 (-170) | Padres -1.5 (+140)
  • Over/Under (O/U): 8.5 (O: -108 | U: -112)

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Guardians at Padres picks and predictions

Prediction

Padres 5, Guardians 4

Moneyline

There is a lean toward playing the Padres and fading the Guardians when considering team performances versus underlying indicators. But the mound match-up, at least in the first 3 or 4 innings, does not line up with a San Diego play.

A Padres -120 or maybe -123 would make for some interest on that side, but otherwise… PASS.

Run line/Against the spread

The Friars are also a would-be lean on the run line, save for the above note on what Weathers does to the equation. Add in a Cleveland penchant for 1-run games (30 so far), and STEER CLEAR.

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Over/Under

San Diego is at its best against lefty pitching (.773 OPS). Both bullpens figure to be sailing along with surface ERA well out of whack with talent levels due to low batting averages on balls in play (Cleveland .259, San Diego .261).

Cleveland’s subpar offense has shown enough signs of life lately — before this series — to be worthy of a piece of an Over.

BACK THE OVER 8.5 (-108).

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Cleveland Guardians at San Diego Padres odds, picks and predictions

Analyzing Wednesday’s Cleveland Guardians at San Diego Padres odds and lines, with expert MLB picks, predictions and best bets.

The Cleveland Guardians (31-35) and the San Diego Padres (32-34) play the middle contest of a 3-game series Wednesday at Petco Park. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 1-0

The Guardians lost 6-3 in the interleague series opener Tuesday against the Padres. Cleveland ranks 27th in the majors in runs scored (253), although it has been picking up the pace lately. The Guardians have managed 75 runs across the past 14 outings, or 5.36 runs per game (RPG). That’s quite a bit better than their overall average of 3.83 RPG this season.

Like Cleveland, San Diego has had trouble scoring runs, posting just 280 runs through 66 games. That’s the 2nd-lowest mark in the National League, ahead of only the lowly Washington Nationals. However, also like Cleveland, the Padres have picked up the pace lately, posting 32 runs across the past 5 games, or 6.4 RPG, well ahead of the season average of 4.24 RPG.

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Guardians at Padres projected starters

RHP Aaron Civale vs. RHP Michael Wacha

Civale (2-1, 2.31 ERA) makes his 5th start. He has a 1.07 WHIP, 2.3 BB/9 and 5.8 K/9 in 23 1/3 innings.

  • Last start: Win, 5 2/3 IP, 2 ER, 4 H, 2 BB, 3 K in a 10-3 home win vs. the Boston Red Sox last Thursday
  • 2023 road splits: 1-0, 0.00 ERA (12 IP, 0 ER, 6 H, 3 BB, 7 K) with a .150 opponent batting average (OBA) in 2 starts

Wacha (6-2, 3.18 ERA) makes his 13th start. He has a 1.09 WHIP, 2.7 BB/9 and 8.5 K/9 in 68 innings.

  • Last start: Win, 6 IP, 0 ER, 2 H, 1 BB, 7 K in a 10-3 home win vs. the Seattle Mariners last Wednesday
  • 2023 home splits: 4-2, 2.93 ERA (40 IP, 13 ER – 4 HR) with a .205 OBA in 7 starts

Guardians at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 7:55 a.m. ET.

  • Moneyline (ML): Guardians +135 (bet $100 to win $135) | Padres -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): Guardians +1.5 (-155) | Padres -1.5 (+125)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Guardians at Padres picks and predictions

Prediction

Padres 4, Guardians 2

Moneyline

The PADRES (-160) is a little on the pricey side, but worth it.

While the Guardians (+135) are 6-1 in the past 7 games following a loss, they’re just 4-10 in the past 14 interleague games and 5-11 in the previous 16 games on the road.

The Padres haven’t done that great in interleague games themselves, but San Diego has ripped off 4 wins in the last 5 games overall.

Run line/Against the spread

The PADRES -1.5 (+125) will take a little bit of a leap of faith. Playing San Diego to win by 2 or more runs has been a dicey proposition.

While it did cash in the series opener, San Diego is just 4-4 as a favorite on the run line in the last 8 games. Play it, but go lightly.

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Over/Under

UNDER 8 (-115) might be the best play on the board.

Civale has been untouchable on the road through 2 starts, although the sample size is obviously pretty small. For Wacha, he has been solid at home, and he doesn’t allow a lot of long balls, not that Cleveland hits many to begin with.

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