San Diego Padres betting odds line spread pick predictions best bets

San Diego Padres at Colorado Rockies odds, picks and predictions

Analyzing Wednesday’s San Diego Padres at Colorado Rockies odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (13-13) take on the Colorado Rockies (6-18) Wednesday in the 3rd game of a 4-game set at Coors Field at 8:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Rockies odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

Colorado rocked the Padres 7-4 Tuesday. The Padres got out to a 4-1 lead in the 3rd and didn’t score again. OF Jackson Merrill went 2 for 3 Tuesday, and his .467 batting average (21 for 45) is the highest road mark in baseball. The Padres are tied for 9th with 4.8 R/game and are 10th with a 3.85 ERA. They are 7-5 on the road thus far.

2B Brendan Rodgers‘ lone hit was the difference Tuesday as it went for a grand slam. The Rockies have just 6 wins on the year, and 4 of them have come at home. Their 6-18 start has tied their worst start in their 32 years as a franchise.

Padres at Rockies projected starters

RHP Matt Waldron vs. TBD

Waldron (0-2, 4.74 ERA) makes his 5th start. He has a 1.53 WHIP, 3.3 BB/9 and 8.5 K/9 over 19 innings.

Last start: Loss, 4 2/3 IP, 5 ER, 7 H, 1 BB, 2 K Friday
Home/road career splits: 1-1, 3.04 ERA, 1.20 WHIP, 5.7 K/9 in 5 road starts; 0-4, 5.61 ERA, 1.43 WHIP and 8.6 K/9 in 7 home games (5 starts)
Has never faced Rockies before

The Rockies have yet to announce a starter for Wednesday.

Rockies are last in MLB with a 5.68 ERA and 1.66 WHIP
Rockies’ bullpen is 23rd in MLB with a 4.88 ERA and last with a 1.58 WHIP

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Padres at Rockies odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:40 p.m. ET.

Moneyline (ML): Padres -160 (bet $160 to win $100) | Rockies +135 (bet $100 to win $135)
Run line (RL)/Against the spread (ATS): Padres -1.5 (-110) | Rockies +1.5 (-110)
Over/Under (O/U): 11 (O: -115 | U: -105)

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Padres at Rockies picks and predictions

Prediction

Padres 7, Rockies 3

Moneyline

The Padres should rebound here as the Rockies could wind up going with a bullpen game. However, dropping -160 on a .500 team with an unknown on the hill isn’t a good use of funds.

Instead, let’s go with MATT WALDRON OVER 3.5 K’S (-135). He has 4+ K’s in 3 of 4 starts, and the Rockies are the 5th-easiest to whiff in baseball.

Run line/Against the spread

We’re projecting a multi-run win for San Diego here, but I don’t like betting -110 on it. Let’s stick with Waldron and take MATT WALDRON UNDER 16.5 OUTS (-135). He has never pitched in Coors Field. He relies on a 91-mph 4-seamer, a knuckleball, sinker, sweeper and cutter. That’s not the repertoire that you can control in the altitude. He also hasn’t pitched 5 2/3 in any of his starts this season.

Over/Under

This one can go either way, but I have trouble betting an Over 11 when Colorado is tied for 24th at 3.7 R/game. The first game of this series went Under, and Tuesday’s game would have pushed.

LEAN UNDER 11 (-105).

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San Diego Padres at Colorado Rockies odds, picks and predictions

Analyzing Monday’s San Diego Padres at Colorado Rockies odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (12-12) open a 4-game series against the Colorado Rockies (5-17) Monday. First pitch from Coors Field is at 8:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Rockies odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 9-4 last year

The Padres snapped a 3-game losing streak with a 6-3 home win over the Toronto Blue Jays Sunday, salvaging 1 game of the 3-game series. Starting RHP Joe Musgrove allowed 3 runs in 7 innings for the win. They are 6-4 in their last 10 games.

The Rockies have lost 7 of their last 8 games and are coming off a 10-2 home loss to the Seattle Mariners Sunday, losing 2 of 3 in the series.

Padres at Rockies projected starters

RHP Dylan Cease vs. LHP Austin Gomber

Cease (2-1, 1.99 ERA) makes his 5th start. He has a 0.93 WHIP, 4.4 BB/9 and 10.7 K/9 in 22 2/3 innings.

Last start: Win, 6 IP, 1 ER, 2 H, 5 BB, 7 K in 6-3 road win over Milwaukee Brewers Tuesday
Has allowed 2 or fewer earned runs in all 4 starts this season

Gomber (0-1, 4.95 ERA) makes his 5th start. He has a 1.50 WHIP, 3.6 BB/9 and 8.1 K/9 in 20 innings.

Last start: Loss, 5 1/3 IP, 3 ER, 6 H, 0 BB, 4 K in 5-0 loss at Philadelphia Phillies Tuesday
Career vs. Padres: 2-3, 3.61 ERA (47 1/3 IP, 19 ER), 1.23 WHIP in 8 starts and 4 relief appearances

Padres at Rockies odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:45 a.m. ET.

Moneyline (ML): Padres -190 (bet $190 to win $100) | Rockies +155 (bet $100 to win $155)
Run line (RL)/Against the spread (ATS): Padres -1.5 (-125) | Rockies +1.5 (+105)
Over/Under (O/U): 10.5 (O: -110 | U: -110)

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Padres at Rockies picks and predictions

Prediction

Padres 5, Rockies 3

Moneyline

Well, the Rockies are 5-17 this season and aren’t even doing well at home. They are 3-6 at Coors Field to start the season. They have been held to 2 or fewer runs in 6 of the last 7 games.

The Padres (-190) are 5-1 in their last 6 games when opponents score 3 or fewer runs. They are 6-4 on the road this season and have won Cease’s last 2 outings.

But betting them at -190 isn’t worth the action.

PASS.

Run line/Against the spread

Nine of the Padres’ 12 wins have been by 2 or more runs.

Twelve of the Rockies’ 17 losses have been by 2 or more runs, including 3 of their last 4.

BET PADRES -1.5 (-125).

Over/Under

While Coors Field has a reputation of high-scoring games, only 4 of 12 contests there this season have had 11 or more total runs.

The Rockies have scored 3 or fewer runs 15 times in 22 outings this season and are 1-14 in those games. Six of their last 8 games have not reached 11 total runs.

BET UNDER 10.5 (-110).

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Toronto Blue Jays at San Diego Padres odds, picks and predictions

Analyzing Saturday’s Toronto Blue Jays at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Toronto Blue Jays (11-9) and San Diego Padres (11-11) play the 2nd game of a 3-game series at Petco Park Saturday. First pitch is scheduled for 8:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Blue Jays vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Blue Jays lead 1-0

The Blue Jays, who were -102 underdogs, won 5-1 in the series opener Friday as the Under (8) cashed. Veteran 3B Justin Turner hit a HR and an RBI single for the Blue Jays, who have won 5 of their last 6 games.

San Diego has lost back-to-back games, scoring just 1 run over its last 2 outings. The Padres had previous put up 6 or more runs in 3 straight wins over the Los Angeles Dodgers and Milwaukee Brewers from Sunday-Tuesday.

Blue Jays at Padres projected starters

RHP José Berríos vs. RHP Randy Vásquez

Berríos (3-0, 1.05 ERA) makes his 5th start. He has a 0.97 WHIP, 2.5 BB/9 and 7.4 K/9 in 25 2/3 innings.

Last start: Win, 7 IP, 0 ER, 2 H, 2 BB, 7 K in 5-0 home victory vs. Colorado Rockies Sunday
2024 road stats: 1-0, 2.25 ERA (12 IP, 3 ER) in 2 starts
Career vs. Padres: 0-2, 2.08 ERA (13 IP, 3 ER) in 2 starts

Vásquez (2-2, 2.87 ERA in 2023) makes his season debut. The rookie had a 1.27 WHIP, 4.3 BB/9 and 7.9 K/9 through 37 2/3 innings across 5 starts and 6 relief appearances for the New York Yankees last year.

2023 home stats: 1-1, 2.25 ERA (20 IP, 5 ER) in 3 starts and 2 relief appearances
Has never faced Blue Jays before

Blue Jays at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:54 a.m. ET.

Moneyline (ML): Blue Jays -120 (bet $120 to win $100) | Padres +100 (bet $100 to win $100)
Run line (RL)/Against the spread (ATS): Blue Jays -1.5 (+145) | Padres +1.5 (-175)
Over/Under (O/U): 8 (O: +100 | U: -120)

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Blue Jays at Padres picks and predictions

Prediction

Padres 3, Blue Jays 2

Moneyline

The PADRES (+100) should snap out of their current offensive slump. Padres 3B Manny Machado had his 11-game hit streak come to an end Friday, but he and RF Fernando Tatís Jr. should be able to provide enough offense to keep Berríos winless in his career against San Diego.

Berríos has allowed just 1 earned run over his last 3 starts, but that level of production is unsustainable. He was inconsistent last season and gave up 4 or more earned runs in 11 of his 32 starts.

BET PADRES (+100).

Run line/Against the spread

The Padres +1.5 (-175) should cover the run line, but I prefer risking 70 cents less on the ML for the same profit.

PASS. Bet the ML and/or total instead.

Over/Under

While it’s unlikely that Berríos can keep playing at this level, I don’t want any part of betting this Over. San Diego has been in a slump for the last 2 games, and Toronto is 22nd in runs per game this season (3.90).

BET UNDER 8 (-120).

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Toronto Blue Jays at San Diego Padres odds, picks and predictions

Analyzing Friday’s Toronto Blue Jays at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Toronto Blue Jays (10-9) and San Diego Padres (11-10) open a 3-game series at Petco Park Friday. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Blue Jays vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 2-1 last season

The Padres are returning home after 2 straight road series. They went 4-2 in those games, losing their last outing 1-0 to the Milwaukee Brewers Wednesday. San Diego is 5-5 straight up at home and 11-10 on the run line this season.

The Blue Jays had their 4-game winning streak snapped in a 6-4 series-finale loss to the New York Yankees Wednesday. They have won 4 of their last 5 and 6 of their last 9. Toronto is 10-9 on the run line this season.

Blue Jays at Padres projected starters

RHP Yariel Rodriguez vs. RHP Matt Waldron

Rodriguez (0-0, 2.45 ERA) makes his 2nd start. The rookie allowed 1 ER on 4 H and 2 BB with 6 K in 3 2/3 IP in his debut, a 5-3 home win, vs. the Colorado Rockies Saturday.

2024 with Buffalo (AAA): Allowed 1 H and 3 BB with 10 K across 6 1/3 scoreless innings in 2 starts
Previously played with the Chunichi Dragons in Japan’s Central League

Waldron (0-1, 3.14 ERA) makes his 4th start. He has a 1.64 WHIP, 3.8 BB/9 and 10.0 K/9 in 14 1/3 innings.

Last start: No-decision, 5 IP, 1 ER, 3 H, 4 BB, 4 K in 5-2 road loss to Los Angeles Dodgers Saturday
Padres are 0-3 in his starts; they were 3-5 in his 8 appearances last season

Blue Jays at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:25 a.m. ET.

Moneyline (ML): Blue Jays -102 (bet $102 to win $100) | Padres -116 (bet $116 to win $100)
Run line (RL)/Against the spread (ATS): Blue Jays -1.5 (+160) | Padres +1.5 (-194)
Over/Under (O/U): 8.5 (O: -104 | U: -118)

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Blue Jays at Padres picks and predictions

Prediction

Padres 6, Blue Jays 3

Moneyline

BET PADRES (-116).

San Diego has been playing well as of late, and its offense has been hot. The Padres have tallied 6 or more runs in 3 of their last 4 games, all of which came against either the Brewers or Dodgers. Milwaukee and Los Angeles each sit atop their respective divisions, and the Padres went 4-2 in back-to-back series against them from April 12-17.

While the Blue Jays have won consistently over their last 5, they haven’t scored more than 5 runs in a game since April 6, so keeping up with the efficient Padres offense could be difficult. Toronto is just 3-6 on the road as well.

Back PADRES (-116).

Run line/Against the spread

PASS.

There’s not great value here, as the Padres are too expensive as run-line underdogs and the Blue Jays don’t have playable odds as run-line favorites.

Over/Under

LEAN OVER 8.5 (-104).

The Blue Jays are 9-9 O/U on the season and have gone Over in 2 straight games. They have scored at least 4 runs in back-to-back games and tallied exactly 5 in 3 of their last 5.

San Diego has gone Over in 3 of its last 4 and in 5 of its last 7. It is 11-9-1 O/U on the season. The Padres have tallied at least 6 runs in 5 of their last 7 as well, so their offense has been consistently producing as of late.

Back OVER 8.5 (-104).

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San Diego Padres at Milwaukee Brewers odds, picks and predictions

Analyzing Tuesday’s San Diego Padres at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (10-9) visit the Milwaukee Brewers (10-5) on Tuesday night. First pitch from American Family Field is scheduled for 7:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 1-0

The Padres have won back-to-back games, both as road underdogs, after taking down the Brewers 7-3 on Monday. After going down by 3 runs early on, the Padres had a 6-run 5th inning to take control. CF Jackson Merrill had 2 RBIs while RHP Joe Musgrove allowed 3 ER in 6 IP to pick up the win.

The Brewers have lost back-to-back games after falling to the Padres on Monday. RF Jackson Chourio had a 2-run HR while RHP Joe Ross allowed 6 ER in 4 2/3 IP and was tagged with the loss.

Padres at Brewers projected starters

RHP Dylan Cease vs. LHP Wade Miley

Cease (1-1, 2.16 ERA) makes his 4th start. He has a 0.84 WHIP, 3.24 BB/9 and 10.8 K/9 in 16.2 IP.

Padres are 1-2 in Cease’s 3 starts this season
Has allowed 4 total ER in 3 games with 20 Ks and 6 BBs
Made 1 career start vs. Brewers while with the Chicago White Sox: Loss, 7 IP, 5 H, 2 ER, 2 BB, 7 K

Miley (0-0, 2.25 ERA) makes his 2nd start. He has a 0.75 WHIP, 4.5 BB/9 and 0.0 K/9 in 4 IP.

Came off injured list to make 1st start last Wednesday; 4 IP, 1 H, 1 ER, 2 BB, 0 K in no-decision vs. Cincinnati Reds
Has pitched for 8 teams and is in his 2nd stint with Milwaukee

Padres at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:13 a.m. ET.

Moneyline (ML): Padres -125 (bet $125 to win $100) | Brewers +105 (bet $100 to win $105)
Run line (RL)/Against the spread (ATS): Padres -1.5 (+135) | Brewers +1.5 (-160)
Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Padres at Brewers picks and predictions

Prediction

Padres 7, Brewers 4

Moneyline

PASS.

The spread presents better value for San Diego (-125).

Run line/Against the spread

BET PADRES -1.5 (+135).

San Diego has won 4 of its last 5 games including 3 of its last 4 on the road. In 3 of its last 4 wins, it has won by 3 or more runs including on Monday against Milwaukee, which has lost back-to-back games by 2-plus runs with each of its last 4 losses being by 2 or more runs.

Over/Under

BET OVER 8.5 (-110).

The Brewers have hit the over in 9 of their last 10 games and have scored 7 or more runs in 6 of their last 8 games while allowing 5 or more runs in 7 of their last 10. The Padres have hit the Over in 4 of their last 5 games and have scored 6 or more runs in 4 of their last 5.

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Chicago Cubs at San Diego Padres odds, picks and predictions

Analyzing Wednesday’s Chicago Cubs at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (7-4) and San Diego Padres (6-8) meet Wednesday in the finale of a 3-game series. First pitch from Petco Park is set for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

The Cubs beat the Padres 5-1 on Tuesday while covering as +124 road underdogs. Chicago scored all 5 of its runs in the 5th inning of a 0-0 game and all 5 runs came via HRs: a solo shot from C Yan Gomes, followed by a grand slam from 3B Christopher Morel.

Padres RHP Joe Musgrove took the loss with 4 IP, 5 H, 4 ER, 3 BB and 5 K. The Padres have not strung together back-to-back wins since March 28.

Cubs at Padres projected starters

RHP Kyle Hendricks vs. RHP Dylan Cease

Hendricks (0-1, 11.74 ERA) makes his 3rd start. He has a 2.74 WHIP, 4.7 BB/9 and 7.0 K/9 in 7 2/3 IP.

Has had a rough start to the year, allowing 17 H, 10 ER with only 6 K in 2 starts
Career vs. San Diego: 8-3, 2.74 ERA (88 2/3 IP, 27 ER), 69 H, 10 BB, 82 K in 14 starts

Cease (0-1, 3.38 ERA) makes his 3rd start. He has a 0.94 WHIP, 3.4 BB/9 and 11 K/9 in 10 2/3 IP.

Last start: No-decision, 6 IP, 4 H, 2 ER, 2 BB, 7 K in a 3-2 loss Friday vs. the San Francisco Giants
Career vs. Cubs: 2-2, 3.45 ERA (28 2/3 IP, 11 ER), 20 H, 14 BB, 36 K in 5 starts

Cubs at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:55 a.m. ET.

Moneyline (ML): Cubs +120 (bet $100 to win $120) | Padres -145 (bet $145 to win $100)
Run line (RL)/Against the spread (ATS): Cubs +1.5 (-165) | Padres -1.5 (+140)
Over/Under (O/U): 8 (O: -115 | U: -105)

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Cubs at Padres picks and predictions

Prediction

Cubs 4, Padres 2

Moneyline

PASS.

This is a very tough game to be confident in either squad as they’re 5-5 in their last 10 meetings. Chicago has been the hotter team to start the season, and Hendricks has been very good in his career vs. the Padres, so they would be my lean here. However, I prefer Chicago’s odds on the run line.

Run line/Against the spread

BET CUBS +1.5 (-165).

Chicago has covered the spread in each of its last 3 games and is 4-1 ATS in its last 5. The Cubs are also 8-3 ATS this season. Chicago has covered ATS in back-to-back matchups vs. San Diego and is 5-2 ATS in the last 7 meetings.

Over/Under

LEAN UNDER 8.5 (-105).

The Under has hit in 6 of San Diego’s last 7 overall and is 3-1 in its last 4 home games. The Under has also hit in 9 of the last 10 Cubs-Padres meetings and is 5-1 in the last 6 meetings in San Diego.

This is only a lean because the Over is 7-4 for Chicago this season and the Padres are 6-7-1 O/U.

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Chicago Cubs at San Diego Padres odds, picks and predictions

Analyzing Tuesday’s Chicago Cubs at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (6-4) continue their 3-game series with the San Diego Padres (6-7) Tuesday. First pitch from Petco Park is scheduled for 10:05 p.m. ET (TBS). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 1-0

San Diego rallied for a 9-8 victory Monday in a roller-coaster ride of a game. The Cubs led 8-0 after 5½ innings, scoring 4 in the 2nd and 4 in the 4th without any homers. But the Padres put together a 7-run 6th inning, behind two 2-run homers — 1 apiece from 1B Jake Cronenworth and 2B Xander Bogaerts.

The Padres took the lead in the bottom of the 8th on RF Fernando Tatis Jr.’s 2-out, 2-run blast and held on for the comeback victory. The last time the Cubs lost after leading by 8 or more runs was in 2002, according to ESPN. It was a run of 234 consecutive victories in the scenario.

Cubs at Padres projected starters

RHP Ben Brown vs. RHP Joe Musgrove

The rookie Brown (0-0, 11.12 ERA) makes his 1st career start. He has a 1.94 WHIP, 4.8 BB/9 and 9.5 K/9 in 5 2/3 innings.

In 1st road appearance, pitched 1 2/3 IP allowing 6 ER — for a 32.40 ERA — on 5 H, 2 BB with 1 K
Vs. left-handed batters (so far): 1.18 OPS with 0 K against 12 plate appearances (10 ABs)

Musgrove (1-1, 6.28 ERA) is slated to make his 4th start. He has a 1.67 WHIP, 2.5 BB/9 and 7.5 K/9 in 14 1/3 innings.

2023 home starts: 6-1, 3.04 ERA, 1.03 WHIP, 9.3 K/9 in 10 starts — 56 1/3 IP
6-1 with 2.12 ERA against opponents with winning records in 2023, vs. 4-1 with 4.08 ERA against teams below .500%.

Cubs at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:55 p.m. ET.

Moneyline (ML): Cubs +120 (bet $100 to win $120) | Padres -145 (bet $145 to win $100)
Run line (RL)/Against the spread (ATS): Cubs +1.5 (-175) | Padres -1.5 (+145)
Over/Under (O/U): 8 (O: +100 | U: -120)

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Cubs at Padres picks and predictions

Prediction

Padres 7, Cubs 6

Moneyline

Monday was a heartbreaker for the Cubs, and Tuesday’s game doesn’t seem like a great comeback spot. The Cubs are 1-3 on the road to start the season. With the Cubs starting a rookie on the hill, I like the Padres.

LEAN SAN DIEGO (-145).

Run line/Against the spread

While Chicago has a poor straight-up record away from the friendly confines, is 3-1 ATS. The Padres, on the other hand, are just 2-6 against the spread at Petco.

But backing Chicago +1.5 (-175) is too chalky, especially since I am picking San Diego on the moneyline.

PASS.

Over/Under

The Cubs are off to a 7-3 O/U record to start the season. Trends for Tuesday’s game point to another high-scoring game. The Over is 5-2 (71.4%) when the Cubs are underdogs, and 3-0 following a Cubs loss. On top of that, the Over is 5-2-1 when the Padres are at home.

BET OVER 8 (+100).

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Chicago Cubs at San Diego Padres odds, picks and predictions

Analyzing Monday’s Chicago Cubs at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (6-3) and San Diego Padres (5-7) open a 3-game series Monday. First pitch from Petco Park is scheduled for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Cubs won 4-3 last season

The Cubs beat the Los Angeles Dodgers 8-1 Sunday and took 2 of 3 games from them in the series. The Cubs got off to a hot start, scoring 3 runs in the 1st inning and 7 by the 4th. A 6th-inning home run from CF Cody Bellinger cemented the Chicago scoring. RHP Yency Almonte picked up the win for Chicago.

The Padres fell 3-2 to the San Francisco Giants Sunday and dropped the series 2 games to 1. San Diego took a 2-1 lead into the 8th inning on account of RBIs from 1B Jake Cronenworth and SS Ha-Seong Kim. RHP Jhony Brito gave up 2 runs in the 8th and picked up the loss for San Diego.

Cubs at Padres projected starters

RHP Javier Assad vs. RHP Yu Darvish

Assad (1-0, 0.00 ERA) makes his 2nd start. He allowed 4 H and 1 BB with 5 K in 6 scoreless innings in his debut vs. the Colorado Rockies Tuesday.

2023 stats: 5-3, 3.05 ERA (109 1/3 IP, 37 ER) in 10 starts and 22 relief appearances

Darvish (0-1, 2.30 ERA) makes his 4th start. He has a 1.09 WHIP, 2.87 BB/9 and 9.19 K/9 in 15 2/3 innings.

Has given up just 4 ER in his 3 previous starts
Has been a victim of his team’s offense; it has scored just 4 combined runs in 2 of his 3 starts
2023 stats: 8-10, 4.56 ERA (136 1/3 IP, 69 ER) in 24 starts

Cubs at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:10 a.m. ET.

Moneyline (ML): Cubs +115 (bet $100 to win $115) | Padres -135 (bet $135 to win $100)
Run line (RL)/Against the spread (ATS): Cubs +1.5 (-175) | Padres -1.5 (+145)
Over/Under (O/U): 7.5 (O: -120 | U: +100)

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Cubs at Padres picks and predictions

Prediction

Cubs 6, Padres 5

Moneyline

BET CUBS (+115).

The Cubs are 6-1 in their last 7 games and have scored at least 8 runs in 5 of their last 7. They have given up 5 or fewer runs in 5 of their last 7. They are 2-1 as underdogs this season.

The Padres have lost 4 of their last 6 at home and have scored 4 or fewer runs in each of their last 6 games. They are just 2-4 in their last 6 games as favorites, all at home.

Run line/Against the spread

PASS.

The profit is higher on the Cubs to win outright.

Over/Under

BET OVER 7.5 (-120).

Chicago has scored 5 or more runs in 6 of its last 7 games and 8 or more in 5 of its last 7. It has allowed 4 or more runs in 6 of its 9 games this season.

San Diego has scored at least 3 runs, and given up 4 or more, in 6 of its last 10 games.

The Cubs and Padres have a combined 11-9 Over record so far this season.

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San Francisco Giants at San Diego Padres odds, picks and predictions

Analyzing Sunday’s San Francisco Giants at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (2-1) and San Diego Padres (2-3) close out a 4-game series Sunday at Petco Park. First pitch is scheduled for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 2-1

San Francisco went 4 for 7 with runners in scoring position in a 9-6 win over San Diego Saturday. Over their 2 wins in this series, the Giants gave gone 9 of 18 in such situations.

The Padres had 3 extra-base hits Saturday. A San Diego club that last year tallied a league-average .413 slugging percentage has banged out 14 extra-base hits over its last 4 games.

Giants at Padres projected starters

RHP Daulton Jefferies vs. RHP Michael King

Jefferies has not pitched in the Majors since 2022; he missed last season recovering from his 2nd Tommy John surgery.

Owns a 5.75 ERA over 14 career games (10 starts)
Pitched 14 innings in spring training, logging a 2.57 ERA with 16 K against 3 BB
Has never faced the Padres

King (4-8, 2.75 ERA with the New York Yankees in 2023) is making his 1st home start with the Padres after being acquired in the Juan Soto trade. Last season, he had a 1.15 WHIP, 2.8 BB/9 and 10.9 K/9 in 104 2/3 innings.

Last outing: Win, 3 1/3 IP, 3 ER, 4 H, 3 BB, 5 K in 15-11 win vs. Los Angeles Dodgers March 21 (in South Korea)
Has faced the Giants once, tossing 1 2/3 innings against them last April 1 (2 R allowed on 4 H and 1 BB; struck out 3)
This game marks his 20th career start; he owns a 3.44 career ERA across 116 games overall

Giants at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:35 a.m. ET.

Moneyline: Giants +115 (bet $100 to win $115) | Padres -135 (bet $135 to win $100)
Run line (RL)/Against the spread (ATS): Giants +1.5 (-175) | Padres -1.5 (+145)
Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Giants at Padres picks and predictions

Prediction

Padres 5, Giants 4

Moneyline

There are too many questions on the Giants side of the ledger, especially with Jefferies getting the nod for the 1st time since May 18, 2022.

King will likely see a hefty contingent of left-handed batters in the San Francisco order, but the former Yankee relief standout has an excellent history against batters of the opposite hand (.656 OPS allowed career, .542 OPSA in 2023).

The Padres went 9-3 at home last September; they are 13-7 across their last 20 home games against San Francisco.

FanDuel Sportsbook has the best value price here: BET THE PADRES (-132).

Run line/Against the spread

PASS: Peg the ML as having the best leverage in this matchup.

Over/Under

The Over has cashed in all 3 games of this series.

Both offenses are clicking so far this season, and there are mound questions on both sides in this series finale. Last September, the Padres got on a roll at home. Over those last 12 games referenced above, they cranked out an .854 OPS while scoring 5.58 runs per game.

San Francisco banged out an .817 OPS in spring training, and batters on both sides get the likely benefit of a significant outward breeze, which is in the forecast. The game could also be in jeopardy due to expected heavy rain.

FanDuel Sportsbook has better leverage: BACK THE OVER 8.5 (-110).

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San Francisco Giants at San Diego Padres odds, picks and predictions

Analyzing Saturday’s San Francisco Giants at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (2-2) welcome the San Francisco Giants (1-1) to Petco Park for the 3rd of a 4-game series Saturday. First pitch is set for 7:15 p.m. ET (FOX). Let’s analyze FanDuel Sportsbook’s lines around the Giants vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1.

The Padres lost their season-opening game 5-2 to the Los Angeles Dodgers but won the following 2, scoring at least 6 in both games. In its 4th game of the season, San Diego lost to the Giants 8-3. It has yet to hold a team to under 4 runs. The Padres finished 3rd in the National League West last season with an 82-80 record. They were 44-37 at home.

The Giants lost to the Padres 6-4 on Opening Day as a slight underdog then took down the Padres 8-3 Friday, closing +124 on the moneyline. The Giants have the league’s 10th-highest payroll, so expectations are high for them this season. San Fran finished last season 79-83 and was 34-47 on the road. They are 1-1 against the spread (ATS) this season and 2-0 O/U.

Giants at Padres projected starters

RHP Jordan Hicks vs. RHP Dylan Cease

Hicks (3-9, 3.29 ERA) made 65 appearances and 0 starts in 2023. He owned a 1.35 WHIP, 4.4 BB/9 and 11.1 K/9 through 65 2/3 IP.

2023 road splits: 2-3, 0.87 ERA (31 IP, 3 ER — 2 HR), 9 BB, 42 K in 31 appearances.
Hasn’t pitched against San Diego since April 7, 2019
Spent last season split between the Cardinals and Blue Jays

Cease (7-9, 4.58 ERA) made 33 starts last season for the White Sox. He finished with a 1.42 WHIP, 4.0 BB/9 and 10.9 K/9 through 177 IP.

2023 home splits: 3-7, 4.20 ERA (94 1/3 IP, 44 ER — 8 HR), 48 BB, 104 K in 17 starts
White Sox were 16-17 in the 33 games Cease started last season
2023 vs. San Francisco: Win, 5 IP, 1 ER (1 HR), 5 BB, 1 H in a 7-3 home victory

Giants at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11 a.m. ET.

Moneyline (ML): Giants +110 (bet $100 to win $110) | Padres -130 (bet $130 to win $100)
Run line (RL)/Against the spread (ATS): Giants +1.5 (-194) | Padres -1.5 (+160)
Over/Under (O/U): 7.5 (O: -112 | U: -108)

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Giants at Padres picks and predictions

Prediction

Padres 5, Giants 3

Moneyline

BET PADRES (-130).

The Giants will likely play most of their game from the bullpen with Hicks transitioning to the rotation. San Fran didn’t have a terrific set or relievers last season, finishing 14th in the MLB in reliever ERA.

San Diego was solid at home last season, ending 44-37. It was also 43-37 following a loss last season. The Padres should have the pitching edge and have tallied at least 6 runs in 2 of their last 3 games.

Take the home side here and back PADRES (-130).

Run line/Against the spread

PASS.

There’s no real value here. The Giants are too expensive to play as a run-line underdog while the Padres are too risky to take as a run-line favorite. Ultimately, the moneyline has the best team-specific value.

Over/Under

LEAN OVER 7.5 (-112).

If there’s one thing both teams have done well this season, it is hit the Over. The Padres are averaging 8 runs per game over their last 3 games and are 3-1 O/U on the season.

The Giants are 2-0 O/U and have scored at least 4 per game while allowing 4.5 per game in their 2 performances this season. Neither team has an ace taking the mound.

With that in mind, expect the offenses to stay hot and take OVER 7.5 (-112).

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