10 Best College Football Predictions Against The Spread Week 10

10 best predictions and picks against the spread and point totals for the Week 10 college football games.

10 best predictions for this week’s college football slate. What games appear to be the best bets and best picks for the Week 10 games?


10 Best College Football Predictions: Week 10

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Expert Picks
Week 10: College Week 9: NFL
Week 10 Game Previews 
Big 12 | Big Ten | SEC

Contact/Follow @ColFootballNews & @PeteFiutak

Results So Far: 53-47-1

This is a serious week that calls for serious predictions.

Besides a few massive whiffs here and there – seriously, thanks SO much, TCU, for that unnecessary TD pass in the final 20 seconds against West Virginia – the biggest complaint comes from those of you wanting bigger picks and bigger calls for the bigger games.

Of course money doesn’t care if it’s on Akron or Alabama, it’s all the same, but every once in a while it’s a little easier to dive in head first into the giant battles with more known parts.

Just ask anyone who thinks they have the MAC clocked this year.

I’ve got a crazy gimmick idea I’ll save for next week with the alternative top ten picks – aka FADE FADE FADE. For now, though, with so much on the line with the Week 10 showdowns, we’re not messing around.

This starts with the giant games everyone will be watching, and yes ATS lovers, these are all going to be picks against the spread …

Except for the two at the very end.

Click on each game for the preview

10. Alabama at LSU

LINE Alabama -13.5
PICK LSU

Full disclosure, I’m not the hugest fan of this pick only because it goes against my DNA to ever pick against Alabama.

I got a hive just writing that.

I know Alabama is amazing when Nick Saban and his $25 million coaching staff get two weeks to figure it all out, and I know Tennessee destroyed LSU 40-13 in Death Valley.

That loss to the Vols was a day game, and we all know LSU is a totally different problem to deal with in Baton Rouge at night.

Tennessee, Texas, and Arkansas were probably the three best teams on the Bama slate so far. All were away from Tuscaloosa, and each one was a problem in its own way.

The Tide will win, but in a nasty road environment against a team that had two weeks off after beating Ole Miss by 25, give me the double digit home dog.

9. Tennessee at Georgia

LINE Georgia -8.5
PICK Georgia

More full disclosure, I think I’ve picked against Tennessee in every game this year. Yeah, that has served me well, so do with this as you will.

8.5 is a LOT to be giving the No. 1 team in the College Football Playoff rankings, but I’m just going come out and say it …

I know this is supposed to be all analytical with logic and rationale, and I hate projecting feelings on an entire team of 18-to-23-year-old kids as if it’s a singular thing. However, I can’t get past the idea that Georgia isn’t going to take being ranked No. 3 all that well.

That might be just that one little bit of extra juice that takes this team to a whole other level of focus.

It’s not like the defending national champ is crawling into this. It won its last three games over Auburn, Vanderbilt, and Florida by a combined score of 141 to 30.  As much as everyone wants to hate on the close call to Missouri, that was the only time anyone came closer than 17 points against this bunch.

Again, Tennessee has made me look ridiculous time and again – I’ve gotten used to it – but as much as I love that the world finally figured out how great Hendon Hooker is, I think this will be about ol’ Stetson Bennett and that Dawg D.

And for the third humongous game of the weekend before we get back to business …

8. Clemson at Notre Dame

LINE Clemson -3.5
PICK Clemson

I missed on Notre Dame against Syracuse last week – for some reason I ignored just how banged up the Orange were – and I totally overloved BYU before Marcus Freeman’s running game went off in Vegas. However, for the most part I’ve been pretty good on my Irish picks.

I took them to cover against Ohio State, thought they’d struggle with Stanford, and had them beating North Carolina. I think I’ve got this one, and it comes down to one simple premise.

Clemson’s NFL defensive front got two weeks off to get ready for this.

It’s Clemson, so of course there won’t be anything easy on the way to the win. However, Notre Dame probably can’t win if it doesn’t run for 200 yards, and Clemson isn’t going to allow that to happen.

Oh, and for all the struggles and problems, no one has come closer than six against the Tigers.

7. South Carolina at Vanderbilt

LINE South Carolina -6.5
ATS PICK Vanderbilt

Vanderbilt is all rested after two weeks off before a home game. It gave Missouri problems in a 17-14 Commodore loss on the road, and South Carolina is coming off an ugly 23-10 loss to Mizzou just last week.

It’s okay. This is an up-and-down Gamecock team, and I’m believing things are about to swing back up.

South Carolina couldn’t run a lick on the Tigers – it’ll run just fine on Vandy. That, and Commodore passing game won’t be accurate enough. It has hit more than 65% of its passes just once, and it lost to Ole Miss by 24.

South Carolina is 5-0 against teams that didn’t connect on 65% of its passes, and 0-3 against teams that did. That, and along with a good day from the ground game, Spencer Rattler will throw for at least 250 yards.

Speaking of Missouri …

6. Kentucky at Missouri

LINE Kentucky -1.5
ATS PICK Missouri

I’ve been trying so hard to make Kentucky a thing. However, my timing is off.

I thought it would get by Ole Miss – nope. Even with quarterback issues I thought it would get by South Carolina – nope. I got the hint and took Mississippi State – nope, the Cats beat the Bulldogs. And then last week I honestly thought UK had the knuckleball style and passing game to maybe catch Tennessee in an all-time sandwich game. Triple nope.

I’m due.

Will Levis is gutting it out, but he’s really hurt. His toughness is a plus for the pro scouts to see, but it’s going to be a problem against a sneaky-amazing Missouri defense that hasn’t allowed 300 yards of total offense in any of the last three games and in four of the last five.

All three Kentucky losses came when it allowed more than 140 yards. Missouri will run for 140, the D will come up with two takeaways, and the secondary should hold up just enough against a game Levis to get the upset.

NEXT: College Football Pick Against the Spread No. 5: Minnesota at Nebraska

College Football Big Game Reaction: Michigan, Baylor, Ohio State, Georgia & More

Quick reaction to the biggest college football games of Week 11: Michigan at Penn State, OU at Baylor, Georgia at Tennessee, Purdue at Ohio State, Texas A&M at Ole Miss

Quick reaction to the biggest games of Week 11: Oklahoma at Baylor, Michigan at Penn State, Georgia at Tennessee, Mississippi State at Auburn


College Football Big Game Reaction: Week 11

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Week 11 Scoreboard, Predictions

Week 11 Big Game Reactions  
Baylor 24, Oklahoma 14 
Michigan 21, Penn State 17
Georgia at Tennessee, Purdue at Ohio State, Texas A&M at Ole Miss and more to come

Baylor 24, Oklahoma 14 Reaction

Oklahoma hasn’t played well, it didn’t have a truly great win over the 9-0 start, and this certainly looked and played like a team that was way, way, way overdue to catch a two-piece, but …

Don’t automatically assume that this team is dead yet.

2020: Lost a Big 12 game. Won Big 12 title.

2019: Lost a Big 12 game. Won Big 12 title, went to CFP.

2018: Lost a Big 12 game. Won Big 12 title, went to CFP.

2017: Lost a Big 12 game. Won Big 12 title, went to CFP.

2016: Lost two non-conference games. Won Big 12 title.

2015: Lost a Big 12 game. Won Big 12 title, went to CFP.

Now, there are a few other parts to this. None of those losses came in November, and none of those Oklahoma teams were as inept as this one appears to be at coming up with a consistent performance.

But enough about Oklahoma. Baylor won this game. Baylor was the tougher teams on the lines, the defense was fantastic, and now its Big 12 title hopes are still alive after losing to TCU last week in a stunner.

The offensive line powered away for close to 300 yards – Abram Smith and QB Gerry Bohanan were fantastic – the defense shut down Caleb Williams and all but ended any Heisman hopes, and when needed, the team pulled away late.

Now it needs to beat Kansas State on the road and get by Texas Tech and get some help, but …

Oklahoma is in the Big 12 Championship if it beats Iowa State and at Oklahoma State.

The way OU is playing, though, that’s not even close to being a given this time around.

NEXT: Michigan 21, Penn State 17 Reaction

Big 12 Predictions, Schedule, Game Previews, Lines, How To Watch: Week 11

Big 12 Schedule, Game Previews, Predictions for Week 11. Oklahoma at Baylor, West Virginia at Kansas State, Iowa State at Texas Tech, Kansas at Texas, TCU at Oklahoma State

Big 12 college football predictions, schedule, game previews, lines, how to watch, and TV listings for Week 11 of the season.


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Click on each game for game preview & prediction 

Week 11 College Football Schedule, Predictions, Game Previews

Big 12 Results So Far
SU: 44-17, ATS: 39-22, Point Total: 31-23-1

Saturday, November 13

Oklahoma at Baylor

12:00, FOX
Line: Oklahoma -5.5, o/u: 62.5

West Virginia at Kansas State

12:00, FS1
Line: Kansas State -6.5, o/u: 47

Iowa State at Texas Tech

3:30, ESPN2
Line: Iowa State -10.5, o/u: 58

Kansas at Texas

7:30, ESPNU
Line: Texas -30.5, o/u: 62

TCU at Oklahoma State

8:00, FOX
Line: Oklahoma State -13, o/u: 54.5

CFN Expert Picks Week 11

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Fearless Predictions of Every Game
Bowl Projections | Rankings

College Football Expert Picks, Predictions: Week 11

College football expert picks and predictions for Week 11’s biggest games including Georgia at Tennessee, Oklahoma at Baylor, and Michigan at Penn State

College football expert picks, predictions for Week 11, highlighted by Georgia at Tennessee, Texas A&M at Ole Miss, Oklahoma at Baylor, and Michigan at Penn State.


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* next to the pick means the team will win, but not cover.
Click on each game for the game preview and CFN Prediction

CFN Fearless Predictions & Game Previews

Week 11 College Football Expert Picks
Buffalo at Miami Univ | Ohio at EMU
Ball State at NIU | Kent State at CMU
North Carolina at Pitt | Cincinnati at USF
Wyoming at Boise St | NMSU at Alabama
Michigan at Penn St | Oklahoma at Baylor
Miss St at Auburn | Northwestern at Wisc
Georgia at Tennessee | Purdue at Ohio St
Minnesota at Iowa | Maryland at Michigan St
Texas A&M at Ole Miss | NC St at Wake Forest
Notre Dame at Virginia | Arkansas at LSU
TCU at Okla State | Wash State at Oregon
Nevada at SDSU | Utah State at SJSU
Results So Far | Week 11 Schedule

Buffalo at Miami University

7:00, ESPNU
Line: Miami University -7.5, o/u: 57

Gill Alexander, VSIN: Miami Univ
Adam Dubbin, GatorsWire.com Miami Univ
Jeff Feyerer, CFN: Buffalo
Pete Fiutak, CFN: Miami Univ.
Dan Harralson, VolsWire.com: Miami Univ*
Phil Harrison, BuckeyesWire.com: Buffalo
Jeremy Mauss, MWwire.com: Miami Univ
Kevin McGuire, NittanyLionsWire.com: Miami Univ*
Johnny Rosenstein, SportsBookWire.com: Miami Univ*
Nick Shepkowski, FightingIrishWire.com: Miami Univ
Scott Steehn, WinnersandWhiners.com: Miami Univ
Joe Vitale, UGAWire.com: Miami Univ
Clucko the Chicken, CFN: Buffalo
CONSENSUS PICK: Miami Univ

NEXT: Ohio at Eastern Michigan Expert Picks, Predictions

10 Best Predictions Against The Spread: Week 12. Reckless And Irresponsible Week

What ten college football games appear to be the best bets and the best picks against the spread going into Week 12? Here you go. Enjoy.

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What ten college football games appear to be the best bets and the best picks against the spread going into Week 12? Here you go. Enjoy.


Week 12 Fearless Predictions, Game Previews 
ACC | Big Ten | Big 12 | Pac-12 | SEC
AAC | C-USA | Ind | MAC | MW | Sun Belt
CFN Fearless Predictions & Game Previews
Week 12 Expert Picks & Predictions
Week 12 Final Thoughts, Betting Advice
10 Best Point Total Predictions


Contact @PeteFiutak

10 Best ATS Picks So Far: 58-55


Click on each game for the game preview and fearless prediction.

Enough safe and sane. It’s time to go against conventional wisdom, blow past everything we know to be dear and true, and make picks based on hardened theories that have worked well before and will now be applied in real time.

What does that all mean?

Welcome to Reckless and Irresponsible Week. They’re the picks you probably shouldn’t make, and in your heart of hearts, can’t make. But at the end of the day, these are will likely be the right ways to go. You’ll see in a moment.

And the ten games that appear to be a wee bit favorable are …

10. Ohio State at Rutgers

LINE: Ohio State -53
Live Stream: fuboTV (click to watch for free)
ATS PICK: Rutgers
Bet on this, BetMGM latest line

We’re going to kick this whole thing off with two hopelessly irresponsible picks – because conflicting predictions and conclusions are exactly what you’re looking for in a Ten Best Picks Against the Spread piece.

The official, more mature prediction in the Ohio State vs. Rutgers Game Preview is different. Of course Ohio State could win this by 54, or 84, or 104 if it wants to. But for anyone familiar with the tried-and-true method with the predictions over the years in this piece – and it worked when New Mexico State visited Alabama, and when UConn went to UCF, among other games – if someone wants to give 50 points or more, you take them, and you don’t ask questions.

Rutgers is going to get up on Saturday morning up 53-0 against Ohio State.

Too many things can go wrong for the Buckeyes not to get there. They have bigger fish to fry, so they might get up 48-0 at halftime, sit everyone, and stall the rest of the game. Rutgers could get a fluky touchdown. Ohio State could be unfocused for a quarter. There could be a lightning strike, a plague of locusts … it’s HARD to win a game by more than 53 points.

Ohio State could totally and completely wipe out the Scarlet Knights and win 55-3.

With all of that in mind, Irresponsible Pick No. 2 …

[lawrence-related id=500213]

9. UMass at Northwestern

LINE: Northwestern -41.5
Live Stream: fuboTV (click to watch for free)
ATS PICK: UMass
Bet on this, BetMGM latest line

There’s one massive difference between this game and the Ohio State-Rutgers game. Northwestern might not be nice, because this is the only time all year the O is going have a little fun.

Northwestern has scored a grand total of 63 points since hanging 30 on UNLV in mid-September, and now you’re asking it to win a game by 42?

UMass has allowed 56 points or more over the last four games to teams like Liberty and UConn, and lost to FIU 44-0. Again, take this with a HUGE grain of salt, because this is more about the Minutemen getting off the bus up 41-0 than what the real pick and prediction is for this week,

If this helps, UMass started out the season losing to Rutgers 48-21.

Part Three of this theme, but not quite as much …

[lawrence-related id=499899]

8. Wake Forest at Clemson

LINE: Clemson -34.5
Live Stream: fuboTV (click to watch for free)
ATS PICK: Wake Forest
Bet on this, BetMGM latest line

Pick against Clemson right now at your own peril, and Wake Forest is coming off a 36-17 loss to Virginia Tech, but there’s just enough offense on the field to at least make this a wee bit closer than the big number.

It’s hardly a plus that top Demon Deacon WR Sage Surratt is done for the year, and Clemson is hanging up 55 on the board without breaking a sweat, but it can win this in a total wipeout and not get to the 35.

The Tigers might have won each of their last four games by well over 35 points each, but the Demon Deacons are just good enough to score a few late points. Clemson will win in an ugly blowout on Senior Day, but in the final Irresponsible Pick of the Week, the team with the nation’s 13th-best offense is already up 34.5-0.

Oh what the heck, let’s just stay Irresponsible and keep the theme going …

[lawrence-related id=500342]

7. Central Michigan at Ball State

LINE: Ball State -2
Live Stream: fuboTV (click to watch for free)
ATS PICK: Ball State
Bet on this, BetMGM latest line

What’s the most reckless way to make a pick? Spite.

Never, ever, ever, ever, chase, and that’s sort of what this pick is.

Who else had Buffalo -5.5 against Kent State?

It took an all-timer of a collapse – Kent State was 0-for-its-last-60 when down 21 points or more – in the fourth quarter to ruin that.

Throw in Toledo’s inexplicable home clunker to Northern Illinois, and Western Michigan coming through on the road in overtime against Ohio, and MACtion owes us.

So the final MAC game of the week is on here, only because we’re due for some puck luck.

Ball State has lost two straight, but Central Michigan isn’t strong on the road – 1-4 with the lone win coming against a bad Bowling Green team. The Chippewas are great overall against the run, but they’re 0-3 when allowing more than 125 rushing yards. NC State and Indiana are the only two teams to hold the Cardinals to under 150.

[lawrence-related id=500133]

6. Florida at Missouri

LINE: Florida -6.5
Live Stream: fuboTV (click to watch for free)
ATS PICK: Florida
Bet on this, BetMGM latest line

It worked just fine putting Florida here last week against Vanderbilt – covering the 26.5 with ease in a 56-0 rout – so let’s not mess with it.

Kelly Bryant is back at quarterback for Mizzou, but he’s less than 100%. There’s some fear that the cold of Columbia could be an issue for the Gainesville guys, but the defense should be just fine against a Tiger O that’s having massive problems scoring. It put up 21 points over the last three games against Vanderbilt, Kentucky and Georgia.

This feels a bit like a trap, but Mizzou has yet to beat at team this year that will go bowling, and the one good team it played – Georgia – just pitched a shutout. If Florida really is the No. 11 team in college football, it wins this in a walk.

NEXT: The Top Five Picks of the Week Against the Spread