Boston College at Notre Dame odds, picks and predictions

Analyzing Saturday’s Boston College at Notre Dame odds and lines, with college football expert picks, predictions and best bets.

The Boston College Eagles (3-7) meet the No. 18 Notre Dame Fighting Irish (7-3) Saturday at Notre Dame Stadium. Kickoff is scheduled for 2:30 p.m. ET (NBC/Peacock). Below, we analyze Tipico Sportsbook‘s lines around the Boston College vs. Notre Dame odds, and make our expert college football picks and predictions.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

The Eagles picked up their 3rd victory of the season in stunning fashion, beating NC State 21-20 to win outright as a 17-point underdog. It was the team’s first win since Oct. 1, although it has covered in back-to-back outings while cashing the Over in each.

The Fighting Irish have scored 35 or more points in each of the last 4 outings, winning each game while also cashing the Over in all 4. It’s been quite the comeback to respectability after a stunning 16-14 loss at home to Stanford on Oct. 15.

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Boston College at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 7:27 a.m. ET.

  • Moneyline (ML): Boston College +900 (bet $100 to win $900) | Notre Dame -1800 (bet $1,800 to win $100)
  • Against the spread: Boston College +20.5 (-109) | Notre Dame -20.5 (-111)
  • Over/Under (O/U): 43 (O: -112 | U: -108)

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Boston College at Notre Dame picks and predictions

Prediction

Notre Dame 41, Boston College 14

Moneyline

Notre Dame (-1800) would cost you 18 times your potential return on the money line, and that’s just too much risk for not nearly enough reward.

PASS.

Against the spread

NOTRE DAME -20.5 (-111) would have been a much riskier play laying this points earlier in the season, but coach Marcus Freeman has this team playing its best football of the campaign.

Notre Dame is averaging 38.8 PPG in the last four 4 games, while allowing 22.8 PPG. Boston College won’t be able to touch that number, as the Eagles offense has issues all season, and it’s a main reason the team isn’t going bowling this season.

B.C. ranks just 117th in total yards per game (322.5), while posting a dismal 62.9 rushing yards per contest, 131st in FBS.

Over/Under

OVER 43 (-112) is the best play on the board, and you might not even need much help from Boston College to get across the finish line.

The Over has hit in 4 in a row for the Irish, while going 6-2 in the last 8 games against ACC opponents.

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Youngstown State at Notre Dame odds, picks and predictions

Analyzing Sunday’s Youngstown State at Notre Dame odds and lines, with college basketball expert picks, predictions and best bets.

The Youngstown State Penguins (2-0) travel to South Bend to take on the Notre Dame Fighting Irish (1-0) Sunday at 4 p.m. ET (ESPN+). Below, we analyze Tipico Sportsbook’s lines around the Youngstown State vs. Notre Dame odds, and make our expert college basketball picks, predictions and bets.

In 2 games early in the season against Canisus and Tennessee-Martin, Youngstown State has scored 90 or more points. They have also given up at least 72 points on both games, leading to both games easily hitting the over. With the 3-point shooting ability of the Irish, this could be another high scoring game.

Notre Dame, in its only game so far, barely prevailed over Radford 79-76 on Thursday. This will be another challenging game for the Irish against a Penguins team which will push the pace and score on them. This will be a difficult matchup for both teams.

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Youngstown State at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:45 a.m. ET.

  • Moneyline (ML): Youngstown State +410 (bet $100 to win $410) | Notre Dame -650 (bet $650 to win $100)
  • Against the spread (ATS): Youngstown State +10.5 (-112) | Notre Dame -10.5 (-112)
  • Over/Under (O/U): 147.5 (O: -115 | U: -110)

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Youngstown State at Notre Dame picks and predictions

Prediction

Notre Dame 83, Youngstown State 77

Moneyline

PASS.

ND should win, but the number for the ML is too high to make it a worthwhile bet.

Against the spread

BET YOUNGSTOWN STATE +10.5 (-112).

The Penguins can score a lot. Far too much for this to get out of hand. While I like the Irish to win the game, I do not think they can score enough or hold the Penguins down enough to cover a double-digit number here. I will take Youngstown State +10.5 (-112).

Over/Under

BET OVER 147.5 (-115).

Scoring will not be an issue in this game. Defense will. Saying this, give me the Over 147.5 (-115) as my favorite play.

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Notre Dame vs. Navy odds, picks and predictions

Analyzing Saturday’s Notre Dame vs. Navy odds and lines, with college football expert picks, predictions and best bets.

The No. 25 Notre Dame Fighting Irish (6-3) meet the Navy Midshipmen (3-6) Saturday on a neutral field at M&T Bank Stadium in Baltimore. Kickoff is scheduled for noon ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Notre Dame vs. Navy odds, and make our expert college football picks and predictions.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports

The Fighting Irish picked up a giant win last week against previously unbeaten Clemson, routing the Tigers 35-14 as 4-point home underdogs. Notre Dame moved to No. 20 on the College Football Playoff standings with the victory.

Notre Dame has scored 35 or more points in 3 straight games — all Over results — after opening 5-1 to the Under in its first 6 games.

The Midshipmen have to win out to become eligible for a bowl game, so for all intents and purposes, their postseason begins Saturday. Navy enters just 1-3 SU across its last 4 outings, but it is a respectable 5-2 ATS in the previous 7 games overall.

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Notre Dame vs. Navy odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 9:16 a.m. ET.

  • Moneyline (ML): Notre Dame -900 (bet $900 to win $100) | Navy +570 (bet $100 to win $570)
  • Against the spread: Notre Dame -14.5 (-109) | Navy +14.5 (-111)
  • Over/Under (O/U): 40.5 (O: -108 | U: -112)

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Notre Dame vs. Navy picks and predictions

Prediction

Notre Dame 34, Navy 13

Moneyline

Notre Dame (-900) will cost you 9 times your potential return in this rivalry game in Baltimore.

Navy catches the Irish at absolutely the worst time this season, as Notre Dame enters brimming with confidence after slaying the Tigers. Still, you can’t lay this kind of money on the Irish for such little return.

PASS.

Against the spread

Playing NOTRE DAME -14.5 (-109) has its risks, especially due to that hook. It would be much more attractive laying less than 2 TDs. Still, this is an Irish team which lit up Clemson by 21 points, and Navy +14.5 (-111) has a much less potent offense.

The key here is the Irish rush defense, which holds the opposition to just 124.3 yards per game on the ground, 35th in the nation. The Middies won’t be able to pass themselves back into the game, and it might snowball pretty badly if Navy falls behind early.

Over/Under

OVER 40.5 (-108) is the best play on the board here, so play it pretty heavily.

Notre Dame has a pretty good chance of racking up enough points to make it go Over on its own if the run game simply hits its averages. Notre Dame runs for 195.1 yards per game, 29th in the country. While Navy is also a running team and running usually means the clock keeps moving and get Under results, this is a super low number.

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Clemson at Notre Dame odds, picks and predictions

Analyzing Saturday’s Clemson Tigers at Notre Dame Fighting Irish odds and lines, with college football expert picks and predictions.

The No. 5 Clemson Tigers (8-0) and Notre Dame Fighting Irish (5-3) clash Saturday at Notre Dame Stadium in South Bend. Kickoff is scheduled for 7:30 p.m. ET (NBC). Below, we analyze Tipico Sportsbook‘s lines around the Clemson vs. Notre Dame odds, and make our expert college football picks and predictions.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Clemson enters this game off back-to-back, 1-score victories followed by a Week 9 bye. The Tigers, the No. 4 team in the first College Football Playoff rankings of the season, survived a somewhat shaky defensive effort in an Oct. 15 win over Florida State (34-28). They overcame 4 turnovers in an Oct. 22 victory over Syracuse (27-21).

The Fighting Irish took down Syracuse Saturday (a week after the Orange fell to Clemson). Notre Dame easily covered a 1.5-point spread in a 41-24 triumph that saw the Irish held an opposing offense under 300 total yards (286) for a 2nd straight week and a 3rd time in 4 weeks. In total defense for the season, UND ranks 28th in FBS (334.5 yards per game).

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Clemson at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 12:01  p.m. ET.

  • Moneyline: Clemson -190 (bet $190 to win $100) | Notre Dame +155 (bet $100 to win $155)
  • Against the spread (ATS): Clemson -3.5 (-110) | Notre Dame +3.5 (-110)
  • Over/Under (O/U): 44.5 (O: -107 | U: -115)

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Clemson at Notre Dame picks and predictions

Prediction

Clemson 24, Notre Dame 17

Moneyline

Its likely the true odds are buried between these prices. PASS.

Against the spread

The Notre Dame run defense may be a bit overrated when looking at analytic measures. Clemson has the ground game to take advantage of this deficit.

And look for the Tigers to finish on the plus side of the field and have the havoc-causing defense to produce a short field or two.

The lean, however, is small. Consider a partial-unit play on CLEMSON -3.5 (-110).

Over/Under

Both Clemson and Notre Dame figure as perhaps a bit too far over their skis in 3rd-down defense. The Irish have been awful in red-zone defense, allowing 20 TDs in as many trips.

The weather report calls for high winds, but figure both sides being able to have enough value drives to spiral this game into the 40s by the 4th quarter.

BACK THE OVER 44.5 (-107).

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Notre Dame at Syracuse odds, picks and predictions

Analyzing Saturday’s Notre Dame at Syracuse odds and lines, with college football expert picks, predictions and best bets.

The Notre Dame Fighting Irish (4-3) and the No. 16 Syracuse Orange (6-1) play Saturday at JMA Wireless Dome. Kickoff is scheduled for noon ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Notre Dame vs. Syracuse odds, and make our expert college football picks and predictions.

The Fighting Irish picked up the 44-21 win over UNLV last weekend at home, bouncing back from an embarrassing 16-14 setback against Stanford as a 16.5-point favorite. While Notre Dame is 4-1 SU in the last 5 games, it is just 2-4 ATS over the previous 6 outings.

The Orange looked like they had it in the bag last week against Clemson in a showdown of unbeatens. Syracuse led 21-10 heading to the 4th quarter, but  outscored by Clemson 17-0 in the final 15 minutes.

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Notre Dame at Syracuse odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 12:03 a.m. ET.

  • Moneyline (ML): Notre Dame +115 (bet $100 to win $115) | Syracuse -140 (bet $140 to win $100)
  • Against the spread: Notre Dame +2.5 (-108) | Syracuse -2.5 (-112)
  • Over/Under (O/U): 47.5 (O: -115 | U: -107)

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Notre Dame at Syracuse picks and predictions

Prediction

Syracuse 27, Notre Dame 20

Moneyline

SYRACUSE (-140) isn’t priced out of line if you just want to pick a winner on the moneyline and not worry about the points.

The Orange have had a nice season, and they’re not going to suffer a 2nd consecutive setback. Syracuse played well enough to win on the road at Clemson, they’re not coming back home and losing to a mediocre Notre Dame side.

Against the spread

SYRACUSE -2.5 (-112) is solid play. This should be a 1-score game, but it will go in the favor of the home side.

The Orange have covered 16 of the last 21 games overall dating back to last season, while hitting in 9 of the last 11 games at home. Syracuse has a perfect 8-0 ATS mark in the last eight games in the month of October, too.

While the Fighting Irish are an impressive 21-8-1 ATS in the last 30 road games, and 5-0 ATS in the last 5 against ACC teams, this is a mediocre team at best. Notre Dame has particularly struggled with the pass on offense, while Syracuse has allowed just 171.4 yards per game through the air, 10th in the nation. Notre Dame is going to have a lot of trouble moving the sticks.

Over/Under

UNDER 47.5 (-107) is the lean here, ever so slightly.

The Under is 5-2 in the last 7 games overall for Notre Dame, while the Under is perfect for Syracuse in the last 4 games. In addition, the Under has cashed in 7 of the last 8 home games for ‘Cuse, while hitting in 4 in a row against teams with a winning overall mark.

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UNLV at Notre Dame odds, picks and predictions

Analyzing Saturday’s UNLV at Notre Dame odds and lines, with college football expert picks, predictions and best bets.

The UNLV Rebels (4-3) and the Notre Dame Fighting Irish (3-3) meet Saturday at Notre Dame Stadium. Kickoff is scheduled for 2:30 p.m. ET (Peacock). Below, we analyze Tipico Sportsbook‘s lines around the UNLV vs. Notre Dame odds, and make our expert college football picks and predictions.

UNLV was sailing along with a 4-1 SU/ATS through its first 5 games, including a nice 58-27 win over North Texas, unbeaten in Conference USA play, back on Sept. 17. However, the Rebels have been outscored 82-14 in their last 2 losses, bringing back those old feelings of frustration for the fanbase while casting doubt for bettors.

Notre Dame has managed a .500 record through 6 games, as the Marcus Freeman era has certainly gotten off to a rocky start. Home losses as a double-digit favorite against Marshall and Stanford have the Irish faithful up in arms, and potential bettors being very careful with their wagers.

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UNLV at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 6:30 a.m. ET.

  • Moneyline (ML): UNLV +1500 (bet $100 to win $1,500) | Notre Dame -10000 (bet $10,000 to win $100)
  • Against the spread (ATS): UNLV +27.5 (-115) | Notre Dame -27.5 (-107)
  • Over/Under (O/U): 47.5 (O: -110 | U: -110)

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UNLV at Notre Dame picks and predictions

Prediction

Notre Dame 34, UNLV 13

Moneyline

Notre Dame (-10000) will cost you way too much for not very much return. It’s a lot of risk for any heavy favorite, but especially so with an inconsistent team like the Irish playing so-so football.

AVOID.

Against the spread

In normal times, when Notre Dame is playing good football, we’d suggest playing the favorite to win this one going away. However, the Irish are just 1-3 ATS as a double-digit favorite this season, including 2 straight-up losses.

Play just a half-unit on UNLV +27.5 (-115) unless this one manages to go over 28 points, then play it a little heavier.

Over/Under

UNDER 47.5 (-110) is the lean, but go lightly. This could easily get away from the Rebels like the last 2 weekends against Air Force and at San Jose State. The Rebels will struggle to put points on the board in this still difficult place to play, while the Irish have also had their issues on offense for most of the season.

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First look: UNLV at Notre Dame odds and lines

Looking at Saturday’s UNLV at Notre Dame college football odds, lines and trends. Here’s what you need to know.

The Notre Dame Fighting Irish (3-3) welcome the UNLV Rebels (4-3) to Notre Dame Stadium Saturday. Kickoff is set for 2:30 p.m. ET (Peacock). Below, we look at UNLV vs. Notre Dame odds from Tipico Sportsbook; check back for all our college football picks and predictions.

UNLV is coming into this game following an embarrassing 42-7 loss to Air Force. With a 40-7 loss to San Jose State the week prior, confidence in the Rebels camp likely isn’t high.

UNLV is captained by coach Marcus Arroyo, who came into the season with a 2-16 record as the program’s leader. With 13 total touchdowns, QB Doug Brumfield has been the key player for UNLV.

Notre Dame, on the other hand, after getting destroyed by Ohio State and then taken down by Marshall to start the season, has won 3 of its last 4 games. It has taken down teams like BYU and UNC.

The Fighting Irish are coached by Marcus Freeman, who is in his first season as the team’s top leader. They’ve allowed more than 21 points in just 2 of 6 games this season.

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UNLV at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:25 a.m. ET.

  • Moneyline (ML): Off the board.
  • Against the spread (ATS): UNLV +24.5 (-110) | Notre Dame -24.5 (-110)
  • Over/Under (O/U): 49.5 (O: -115 | U: -107)

2022 betting stats

  • ML: UNLV 4-3 | Notre Dame 3-3
  • ATS: UNLV 4-3 | Notre Dame 3-3
  • O/U: UNLV 3-4 | Notre Dame 1-5

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UNLV vs. Notre Dame head-to-head

With UNLV in the Mountain West Conference and Notre Dame independent, it is not shocking that these teams have never met before.

Notre Dame under Freeman, who is a long-time coach on the defensive side of the ball, allows just 22 points per game, ranking 36th of 131 FBS programs. Its offense has done little to help its cause this season.

For UNLV, Brumfield is a stud, but RB Aidan Robbins has also done well, totaling 591 rushing yards. The Rebels are huge underdogs, partly due to being on the road and partly because they haven’t been tested either, ranking 115th in strength of schedule.

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Stanford at Notre Dame odds, picks and predictions

Analyzing Saturday’s Stanford at Notre Dame odds and lines, with college football expert picks, predictions and best bets.

The Stanford Cardinal (1-4) and the Notre Dame Fighting Irish (3-2) meet at Notre Dame Stadium in South Bend, Ind. Kickoff is scheduled for 7:30 p.m. ET (NBC/Peacock). Below, we analyze Tipico Sportsbook‘s lines around the Stanford vs. Notre Dame odds, and make our expert college football picks and predictions.

The Cardinal suffered a heartbreaking loss against Oregon State last week, losing 28-27 on the final ticks on The Farm. On a positive note, it was Stanford’s first cover of the season in 5 tries, but it is now 0-4 SU in 4 games against FBS teams. The Over is also on a 4-0 run.

The Fighting Irish topped BYU in Las Vegas last week by a 28-20 count, picking up a 3rd consecutive victory, while covering the 2nd in a row. The Under has cashed in 4 of 5 games overall for the Irish.

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Stanford at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:55 a.m. ET.

  • Moneyline (ML): Stanford +570 (bet $100 to win $570) | Notre Dame -850 (bet $850 to win $100)
  • Against the spread (ATS): Stanford +16.5 (-110) | Notre Dame -16.5 (-110)
  • Over/Under (O/U): 53.5 (O: -110 | U: -110)

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Stanford at Notre Dame picks and predictions

Prediction

Notre Dame 41, Stanford 27

Moneyline

Notre Dame (-850) will cost you 8 1/2 times your potential return, and that’s a ridiculous bet. Over the long term, betting with that kind of strategy is a losing proposition.

PASS.

Against the spread

STANFORD +16.5 (-110) doesn’t look terribly attractive since it is winless in 4 tries against FBS teams so far. However, this is the College Football Playoff for the Cardinal. This might even be their bowl game against their rival.

Stanford has shown a pretty decent ability to roll up points, going for 27 or more points in 4 of 5 games. Defense is where the Cardinal have struggled, and that will continue in the shadow of Touchdown Jesus Saturday.

Over/Under

OVER 53.5 (-110) is the best play on the board in this rivalry game.

The Over is 4-0 in the past 4 games for the Cardinal, while going 5-2 in the past 7 on the road, and 5-0 in the past 5 against winning teams. Not to mention, the Cardinal defense is an absolute sieve.

While it’s all about the Under for the Fighting Irish, it should have a tremendous offensive outburst in this one.

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BYU vs. Notre Dame odds, picks and predictions

Analyzing Saturday’s BYU vs. Notre Dame odds and lines, with college football expert picks, predictions and best bets.

The No. 16 BYU Cougars (4-1) take on the Notre Dame Fighting Irish (2-2) Saturday in prime time on a neutral field. Kickoff is Saturday at 7:30 p.m. ET at Allegiant Stadium in Las Vegas (NBC, Peacock). Below, we analyze Tipico Sportsbook‘s lines around the BYU vs. Notre Dame odds, and make our expert college football picks and predictions.

BYU is No. 16 in the AFCA Coaches Poll powered by USA TODAY Sports. The Cougars have won 2 games in a row after starting the season with 2 straight wins and a loss. Their lone loss was to then-No. 25 Oregon.

Notre Dame entered this season No. 5 in preseason rankings. They have rallied for 2 straight wins over California and North Carolina after losing to Ohio State and Marshall to start the season.

Check out: AFCA Coaches Poll powered by USA TODAY sports

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BYU vs. Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 9 a.m. ET.

  • Moneyline (ML): BYU +165 (bet $100 to win $165) | Notre Dame -200 (bet $200 to win $100)
  • Against the spread (ATS): BYU +3.5 (-107) | Notre Dame -3.5 (-115)
  • Over/Under (O/U): 51.5 (O: -105 | U: -120)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

BYU vs. Notre Dame picks and predictions

Prediction

BYU 31, Notre Dame 27

Moneyline

The game atmosphere will be great with 2 fanbases that are everywhere nationwide. Notre Dame has increased its point total each week, peaking with 45 points last weekend. The Fighting Irish have won the last 3 matchups, but the teams have not played since 2013.

BYU has scored 26 or more in 4 of their 5 games, scoring 20 in their lone loss this season. BYU’s offensive attack is diverse. Four different players have more than 190 receiving yards, and 2 have more than 160 rushing yards.  QB Jaren Hall has 12 touchdown passes to only 1 interception.

Notre Dame has two players with more than 200 receiving yards, but no one else has even reached 100.

Take BYU (+165).

Against the spread

BYU is 2-3 ATS this season and Notre Dame is 2-2 ATS.

Notre Dame allowed 32 points last week to North Carolina. BYU put up 38 each of the last 2 weeks.

BYU’s defense showed it can slow stronger programs with its overtime win over Baylor.

Expecting the upset, I like the Cougars on the moneyline, but if you aren’t as sure, this could be a game that goes down to the wire and will come down to a late field goal.

Take BYU +3.5 (-107).

Over/Under

BYU’s last 3 games have all had totals of more than 60.

The only game for Notre Dame to even get the 50s was their win last week, which had 77 total points.

But with both teams trending toward scoring more, take OVER 51.5 (-105).

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Want action on this game or any other NCAA football matchup? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / USC / Wisconsin / College Football News

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Notre Dame at North Carolina odds, picks and predictions

Analyzing Saturday’s Notre Dame at North Carolina odds and lines, with college football expert picks, predictions and best bets.

The Notre Dame Fighting Irish (1-2) and the North Carolina Tar Heels (3-0) meet Saturday at Kenan Stadium in Chapel Hill. Kickoff is scheduled for 3:30 p.m. ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Notre Dame at North Carolina school odds, and make our expert college football picks and predictions.

The Fighting Irish picked up their first win of the season, defeating California 24-17 last weekend after losses to Ohio State and Marshall in the first two weekends. The Irish are still 1-2 ATS, and the Under has cashed in all 3 games.

The Tar Heels picked up a 2nd consecutive road win inside the dangerous Sun Belt Conference, winning 35-28 at Georgia State. UNC is 3-0 despite allowing 24 or more points in each outing.

Check out: AFCA Coaches Poll powered by USA TODAY sports

Stream select live college football games and full replays: Get ESPN+

Notre Dame at North Carolina odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:45 a.m. ET.

  • Money line (ML): Notre Dame +115 (bet $100 to win $115) | North Carolina -135 (bet $135 to win $100)
  • Against the spread (ATS): Notre Dame +2.5 (-108) | North Carolina -2.5 (-112)
  • Over/Under (O/U): 55.5 (O: -112 | U: -108)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Notre Dame at North Carolina picks and predictions

Prediction

North Carolina 31, Notre Dame 27

Money line

NORTH CAROLINA (-135) is a strong play at home against a stumbling Notre Dame team, which has struggled offensively.

The Fighting Irish started QB Tyler Buchner in the first 2 games, but he suffered a season-ending shoulder injury against Marshall. QB Drew Pyne took over as the starter in the win over Cal, but it was a choppy performance, and the Irish will have to be on point to keep up with the high-octane UNC offense.

Against the spread

NORTH CAROLINA -2.5 (-112) is worth a look on its home field.

The Tar Heels have struggled defensively, allowing 468.3 total yards per game to rank 123rd in the nation, while coughing up 37.7 points per game. That’s the concern here, although their problems on D should be masked a bit with the Irish starting a backup QB still cutting his teeth.

Over/Under

BET OVER 55.5 (-112).

Yes, Notre Dame has cashed the Under in all 3 of its games, struggling to score points, while playing strong defense.

But I’m not playing Under and UNC ever, as this team struggles so much on defense, and can score tons of points on the other side of the ball.

Play our free daily Pick’em Challenge and win! Play now!

Want action on this game or any other NCAA football matchup? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Kevin J. Erickson on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / USC / Wisconsin / College Football News

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