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The Notre Dame Fighting Irish (4-1) and the Duke Blue Devils (4-0) meet Saturday at Wallace Wade Stadium in Durham, N.C. Kickoff is scheduled for 7:30 p.m. ET (ABC). Below, we analyze FanDuel Sportsbook’s lines around the Notre Dame vs. Duke odds, and make our expert college football picks and predictions.
The Fighting Irish lost 17-14 in the most excruciating way possible last week against Ohio State, allowing the go-ahead TD on the final play of regulation. The Irish still hung on for the cover at most shops, cashing as 3.5-point underdogs as the Under (55.5) connected, ending a 3-0 run to the Over.
The Blue Devils keep steaming ahead, spanking UConn 41-7 on the road last week. Not everyone was happy, as Under bettors had about the worse bad beat you’ll ever see. The Huskies scored their lone points with 12 seconds left in regulation to flip the total (45).
Duke is 3-0 ATS against FBS opponents this season, and the Over is 2-0-1 in the past 3 outings after an Under result in its upset win over Clemson on Labor Day night.
Notre Dame leads the all-time series 5-2, including a 38-7 win in its last visit to Durham on Nov. 9, 2019.
Notre Dame is No. 13 and Duke is No. 16 in the US LBM Coaches Poll powered by USA TODAY Sports.
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Notre Dame at Duke odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 7:02 a.m. ET.
- Moneyline (ML): Notre Dame -215 (bet $215 to win $100) | Duke +176 (bet $100 to win $176)
- Against the spread (ATS): Notre Dame -5.5 (-115) | Duke +5.5 (-105)
- Over/Under (O/U): 52.5 (O: -115 | U: -105)
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Notre Dame at Duke picks and predictions
Prediction
Notre Dame 34, Duke 23
Moneyline
Notre Dame (-215) looks to bounce back after the devastating home loss. In the grand scheme of things, a 3-point setback to Ohio State, a top-5 team, isn’t going to disqualify the Irish from the playoff conversation, especially losing on the final play. It was a super-close game. However, it needs to win out, and can gather some momentum with a road win against a top-20 team.
AVOID, and look to the spread instead.
Against the spread
NOTRE DAME -5.5 (-110) is a great play, and it’s surprising that this line isn’t much higher.
The Fighting Irish have QB Sam Hartman and a tremendous passing attack, but the offense is well balanced, with RB Audric Estime racking up 7.7 yards per game with 5 rushing TDs in 5 games. This is a powerful type of offense that Duke +5.5 (-110) just hasn’t seen all season. You might say Clemson, but the Tigers are just 2-2, and that Duke upset on Labor Day is looking a little less impressive.
Over/Under
OVER 52.5 (-115) is the lean, as Notre Dame looks to get the offense untracked.
Notre Dame had scored 41 or more points in the first 4 games before being stymied by the Ohio State defense last weekend.
Duke has been surprisingly explosive, going for 38 or more points in each of the past 3 games, while cashing the Over in the previous 2 outings. The Blue Devils defense has allowed a total of just 35 points, including exactly 7 in 3 outings. However, facing UConn, Northwestern and Lafayette is a lot different than facing Notre Dame.
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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
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