The Arizona Diamondbacks take on the San Diego Padres in their 2020 MLB season opener Friday at Petco Park for a 9:10 p.m. ET first pitch. We analyze the Diamondbacks-Padres MLB betting odds and lines, with betting advice and tips around the matchup.
Diamondbacks at Padres: Projected starting pitchers
LHP Madison Bumgarner vs. RHP Chris Paddack
Bumgarner (2019, San Francisco Giants): 9-9, 3.90 ERA, 203 K, 43 BB
- Bumgarner is making his Arizona debut but is an Opening Day starter for the sixth time.
- He was 2-1 in four starts against the Padres in 2019 with an ERA of 4.00 and .852 WHIP.
Paddack (2019): 9-7, 3.33 ERA, 153K, 31 BB
- Paddack was stellar in three starts against Arizona in 2019, going 1-0 with a 1.08 ERA and 20 strikeouts in 16 2/3 innings.
- He is making his first Opening Day start.
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Diamondbacks at Padres: Key injuries
Visit sportsdata.usatoday.com to track all MLB injuries leading up to game time.
Diamondbacks
- 1B Christian Walker (groin) is expected to be the DH in the opener
- RP Silvino Bracho (elbow) is out for the season after Tommy John surgery
Padres
- SS Jorge Mateo (COVID-19) is out indefinitely
- RP Jose Castillo (back) is expected to be out until mid-August
Diamondbacks at Padres: Odds, lines, picks and betting tips
MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated Friday at 7:10 a.m. ET.
Prediction
Padres 5, Diamondbacks 4
Moneyline (ML)
The Padres are favored in their season opener at -133, while the D-Backs are +120 underdogs. Paddack dominated Arizona in 2019 and Arizona’s offense was anemic in their tune-up games in Los Angeles. Take the PADRES -133.
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Run line/Against the spread (ATS)
Arizona was one of the best against the run line in 2019, going 90-72 against the spread. This will be a closely contested game. Bet the DIAMONDBACKS +1.5 (-182).
Over/Under (O/U)
The total is set at 8.5 runs. Arizona’s lineup is improved over last year and averaged five runs per game. Bumgarner will get out of the gate slowly and the D-Backs will rally. Take the OVER 8.5 (-110).
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