Louisville Cardinals betting odds lines ML ATS OU

Louisville vs. Stanford odds, picks and predictions

Analyzing Saturday’s Louisville at Stanford odds and lines, with college football expert picks, predictions and best bets.

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The No. 24 Louisville Cardinals (6-3, 4-2 ACC) meet the Stanford Cardinal (2-7, 1-5) at Stanford Stadium Saturday. Kickoff is at 3:30 p.m. ET (ACC Network). Below, we look at Louisville vs. Stanford odds from BetMGM Sportsbook’s college football odds and make our expert college football picks and predictions.

Louisville secured its third win in the last 4 games, defeating the Clemson Tigers 33-21 as 10.5-point road underdogs while the Under 62.5 hit. RB Isaac Brown led the way with 151 yards on 20 carries and a TD.

Stanford has lost 6 straight games, with their latest defeat 59-28 at the N.C. State Wolfpack. They failed to cover as 9.5-point underdogs while the Over 46.5 hit. Stanford’s defense allowed 281 rushing yards and 5 TDs. QB Ashton Daniels was the lone bright spot, rushing for 129 yards and 2 TDs on 11 carries.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Louisville vs. Stanford odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 1:43 p.m. ET.

Moneyline (ML): Louisville -1400 (bet $1,400 to win $100) | Stanford +825 (bet $100 to win $825)
Against the spread (ATS): Louisville -20.5 (-110) | Stanford +20.5 (-110)
Over/Under (O/U): 57.5 (O: -110 | U: -110)

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Louisville vs. Stanford picks and predictions

Prediction

Louisville 41, Stanford 14

Moneyline

PASS.

Louisville (-1400) will win this game comfortably, which is why you should take your wager to the spread.

Against the spread

BET LOUISVILLE -20.5 (-110).

Louisville enters this game after a bye week and riding a 2-game win streak, including a road victory over Clemson. Meanwhile, Stanford has dropped 6 straight games, with a defense that has allowed 40+ points in 3 of its last 4 outings. The Cardinal have also failed to cover in their last 10 November home games. Louisville has covered in 5 of its last 6 November road games against unranked teams. Stanford’s defense gives up an average of 34.6 points per game, and with recent struggles, it’s hard to back them here. Take Louisville to win on the road.

Over/Under

BET UNDER 57.5 (-110).

Louisville and Stanford are trending in opposite directions for totals, with the Cardinals hitting the over in 6 of 9 games and the Cardinal hitting the under in 6 of 9. The line is set at 58.5, reflecting expectations for Louisville to dominate and Stanford to control the clock. Stanford has gone under in 2 of its last 3 games, while Louisville has gone 2-2 in their last 4. With Stanford focusing on a run-heavy offense and Louisville not needing a huge margin for the playoffs, the Over seems unlikely. Louisville’s focus will shift to securing a bowl game rather than running up the score.

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First look: Louisville at Clemson odds and lines

Looking at Sunday’s Louisville at Clemson college football odds, lines and trends. Here’s what you need to know.

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The Louisville Cardinals (5-3, 3-2 ACC) visit the 8th-ranked Clemson Tigers (6-1, 5-0) Saturday night. Kickoff from Memorial Stadium is scheduled for 7:30 p.m. ET (ESPN). Below, we look at Louisville vs. Clemson odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

Louisville got back in the win column Saturday with a 31-27 win at Boston College, but the Cardinals failed to cover as 7-point road favorites. QB Tyler Shough went 28 of 38 for 332 passing yards with 2 TDs and 2 interceptions in the win.

Clemson is coming off a bye week after extending its winning streak to 6 games with a 48-31 victory over Virginia Oct. 19th, while failing to cover as a 20.5-piont home favorite. QB Cade Klubnik went 23 of 35 for 308 yards with 3 TDs and an interception in the win.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Louisville at Clemson odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Tuesday at 3:30 a.m. ET.

Moneyline (ML): Louisville +310 (bet $100 to win $310) | Clemson -400 (bet $400 to win $100)
Against the spread (ATS): Louisville +10.5 (-110) | Clemson -10.5 (-110)
Over/Under (O/U): 61.5 (O: -110 | U: -110)

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2024 betting stats

ML: Louisville 5-3 | Clemson 6-1
ATS: Louisville 3-5 | Clemson 4-3
O/U: Louisville 6-2 | Clemson 3-4

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Louisville vs. Clemson head-to-head

Louisville and Clemson have faced off 8 times in program history dating back to 2014 with Clemson dominating the series 8-0.

The last time the teams played was in November 2022 with Clemson taking down Louisville 31-16 and covering as a 7-point home favorite. The Under (52) narrowly hit with both teams combining for 839 yards of total offense — Clemson 439, Louisville 400.

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First look: Miami at Louisville odds and lines

Looking at Saturday’s Miami at Louisville college football odds, lines and trends. Here’s what you need to know.

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The 6th-ranked Miami Hurricanes (6-0, 2-0 ACC) travel to meet the unranked Louisville Cardinals (4-2, 2-1) Saturday at L&N Federal Credit Union Stadium. Kickoff is scheduled for noon ET (ABC/ESPN+). Below, we look at Miami vs. Louisville odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

The Hurricanes are coming off a bye following 2 wins with controversial finishes — at home against Virginia Tech and on the road at Cal. After opening the season 3-1 against the spread (ATS) in the first 4 games, the Hurricanes are 0-2 ATS in the past 2 outings. The Over has cashed at a 5-0-1 pace.

Louisville eased by Virginia 24-20 in Charlottesville Saturday, but it failed to cover as a 7-point favorite. After opening 3-0 ATS in the first 3 games, the Cardinals have failed to cover in the past 3 outings. The Cardinals are back home where they’re 3-1 SU/ATS in 4 games, with the Over going 3-1, too.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Miami at Louisville odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Monday at 7:07 a.m. ET.

Moneyline (ML): Miami -175 (bet $175 to win $100) | Louisville +145 (bet $100 to win $145)
Against the spread (ATS): Miami -4 (-110) | Louisville +4 (-110)
Over/Under (O/U): 61.5 (O: -110 | U: -110)

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2024 betting stats

ML: Miami 6-0 | Louisville 4-2
ATS: Miami 3-3 | Louisville 3-3
O/U: Miami 5-0-1 | Louisville 4-2

Miami vs. Louisville head-to-head

Miami leads the all-time series 11-4-1, but the Cardinals won the most recent meeting 38-31 as a 1-point underdog at Hard Rock Stadium in Miami Gardens last November.

The last time these teams met in Louisville, the ‘Canes came away with a 47-34 win Sept. 19, 2020.

The Cardinals have won 4 of the past 6 meetings since Sept. 16, 2006, including a meeting in the 2013 Russell Athletic Bowl in Orlando.

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First look: Louisville at Notre Dame odds and lines

Looking at Saturday’s Louisville at Notre Dame college football odds, lines and trends. Here’s what you need to know.

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The No. 17 Louisville Cardinals (3-0) take on the No. 14 Notre Dame Fighting Irish (3-1) Saturday at Notre Dame Stadium. Kickoff for is set for 3:30 p.m. (Peacock). Below, we look at Louisville vs. Notre Dame odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

Louisville prevailed 31-19 against Georgia Tech Saturday, covering as a 9.5-point home favorite. QB Tyler Shough was 13-for-19 for 269 yards with 2 TDs and 0 interceptions. The Cardinals only managed 57 yards on the ground on 27 rushes, but 2 defensive touchdowns were paramount.

Notre Dame took down the Miami (Ohio) RedHawks 28-3 last week. The Irish dropped to 2-2 against the spread (ATS) after failing to cover as 27-point home favorites. They are 0-2 ATS when favored by more than 7 points. RB Riley Leonard finished with 143 rushing yards with 2 TDs on 12 carries.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Louisville at Notre Dame odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Tuesday at 2:26 a.m. ET.

Moneyline (ML): Louisville +185 (bet $100 to win $185) | Notre Dame -225 (bet $225 to win $100)
Against the spread: Louisville +6 (-110) | Notre Dame -6 (-110)
Over/Under (O/U): 48.5 (O: -110 | U: -110)

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2024 betting stats

ML: Louisville 3-0 | Notre Dame 3-1
ATS: Louisville 3-0 | Notre Dame 2-2
O/U: Louisville 2-1 | Notre Dame 1-3

Louisville at Notre Dame head-to-head

The all-time series is tied 2-2. Louisville won the 1st meeting 31-28 as a 3-point underdog in South Bend in 2014, a year after Louisville moved to the ACC.

While the series is tied, Louisville is 4-0 ATS in all 4 games.

The Cardinals took the last matchup 33-20, covering as 6-point home dogs Oct. 3, 2023. The Cardinals held the Irish to just 44 yards on the ground while rushing for 185 yards themselves in that win.

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First look: Georgia Tech at Louisville odds and lines

Looking at Saturday’s Georgia Tech at Louisville college football odds, lines and trends. Here’s what you need to know.

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The Georgia Tech Yellow Jackets (3-1, 1-1 ACC) and the Louisville Cardinals (2-0, 0-0) play an ACC matchup Saturday at L&N Federal Credit Union Stadium. Kickoff is scheduled for 3:30 p.m. ET (ESPN2). Below, we look at Georgia Tech vs. Louisville odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

The Yellow Jackets opened the season with a 24-21 upset win against Florida State in Ireland. It returned to the States, topping Georgia State at home 35-12 for a cover as 20.5-point favorites. In its 1st true road game, Georgia Tech lost at Syracuse 31-28 as a 3-point favorite as the Under (60.5) cashed.

The Yellow Jackets are coming off a 59-7 win over VMI of the FCS, cashing as a 44-point favorite while taking care of the Over (53) on their own. The Under is 3-0 in 3 games against FBS opponents.

The Cardinals topped FCS Austin Peay 62-0 in the Aug. 31 opener as a 39.5-point favorite as the Over (55.5) cashed. Louisville spanked Jacksonville State 49-14 on Sept. 7 as a 28.5-point favorite, again as the Over (55.5) hit. Last week, Louisville was on a bye.

Louisville is No. 20 in the US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Georgia Tech at Louisville odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Monday at 6:11 a.m. ET.

Moneyline (ML): Off the board
Against the spread (ATS): Georgia Tech +10 (-110) | Louisville -10 (-110)
Over/Under (O/U): 57.5 (O: -110 | U: -110)

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2024 betting stats

ML: Georgia Tech 3-1 | Louisville 2-0
ATS: Georgia Tech 3-1 | Louisville 2-0
O/U: Georgia Tech 1-3 | Louisville 2-0

Georgia Tech vs. Louisville head-to-head

This is the 4th all-time meeting between these ACC teams.

The Cardinals picked up a 39-34 victory on the road against the Yellow Jackets on Sept. 1, 2023 last season as the Over (49.5) comfortably cashed.

Georgia Tech won the previous 2 meetings, including the only other meeting in Louisville on Oct. 5, 2018. The Jackets won 66-31 in that one. The Yellow Jackets are 3-0 ATS in all 3 meetings, while the Over is also 3-0.

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First look: Duke at Louisville odds and lines

Looking at Saturday’s Duke at Louisville college football odds, lines and trends. Here’s what you need to know.

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The Duke Blue Devils (5-2, 2-1 ACC) meet the Louisville Cardinals (6-1, 3-1) on Saturday at Cardinal Stadium in Louisville, Ky. Kickoff is scheduled for 3:30 p.m. ET (ESPN). Below, we look at Duke vs. Louisville odds from FanDuel Sportsbook. Also see: SportsbookWire’s college football picks and predictions.

The Blue Devils held a surprising 20-17 lead at halftime of their game at Florida State on Saturday, but the Seminoles outscored Duke 21-0 in the final 15 minutes for the 38-20 win. Duke failed to cover the 13.5-point number as the Over (49) cashed. After a 4-0 straight up (SU) and 3-1 against the spread (ATS) start, the Blue Devils are 1-2 SU/ATS in the past 3 games.

The Cardinals have been stewing for 2 weeks after a stunning loss at Pittsburgh as a 7-point favorite, falling 38-21. That snapped a 6-game win streak to start the season, including a signature win over Notre Dame on Oct. 7. The Cards are both 3-3-1 ATS and OU so far this season.

Duke is No. 21 and Louisville is No. 18 in the US LBM Coaches Poll powered by USA TODAY Sports.

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Duke at Louisville odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:38 a.m. ET.

Moneyline (ML): Duke +172 (bet $100 to win $172) | Louisville -210 (bet $210 to win $100)
Against the spread (ATS): Duke +4.5 (-104) | Louisville -4.5 (-118)
Over/Under (O/U): 47.5 (O: -110 | U: -110)

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2023 betting stats

ML: Duke 5-2 | Louisville 6-1
ATS: Duke 4-3 | Louisville 3-3-1
O/U: Duke 3-3-1 | Louisville 3-3-1

Duke at Louisville head-to-head

The Blue Devils and Cardinals have met just 3 previous times on the gridiron, with Louisville winning each of the outings by 10 or more points. Louisville embarrassed Duke at Wallace Wade Stadium in a Thursday night game in 2021, winning 62-22 in former coach David Cutcliffe’s final season.

The last and only time these teams met in Louisville, the Cards came away with a 24-14 win in 2016.

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First look: Notre Dame at Louisville odds and lines

Looking at Saturday’s Notre Dame at Louisville college football odds, lines and trends. Here’s what you need to know.

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The No. 11 Notre Dame Fighting Irish (5-1) take on the No. 25 Louisville Cardinals (5-0) in Louisville on Saturday at 7:30 p.m. (ABC). Below, we analyze FanDuel Sportsbook’s lines around the Notre Dame vs. Louisville odds, and make our expert college football picks and predictions.

Notre Dame is coming off a defensive struggle against Duke on Saturday. Entering the game as 4.5-point favorites, Notre Dame pulled out a last minute 21-14 win to cover.

Louisville had its toughest game to date last Friday scratching out a 13-10 road win as 3-point favorites against NC State. Notre Dame will be coach Jeff Brohm’s biggest test to keep the Cardinals undefeated.

Notre Dame is No. 11 and Louisville No. 25 in the US LBM Coaches Poll powered by USA TODAY Sports.

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Notre Dame at Louisville odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 10:25 a.m. ET.

Moneyline (ML): Notre Dame -260 (bet $260 to win $100) | Louisville +210 (bet $100 to win $210)
Against the spread (ATS): Notre Dame -7 (-105) | Louisville +7 (-115)
Over/Under (O/U): 51.5 (O: -110 | U: -110)

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2023 betting stats

ML: Notre Dame 5-1 | Louisville 5-0
ATS: Notre Dame 5-1 | Louisville 2-2-1
O/U: Notre Dame 3-3 | Louisville 2-2-1

Notre Dame vs. Louisville head-to-head

These teams have only played 3 times in their history and in all 3 games the favorite has failed to cover while the Over has hit once.

The last meeting between the schools was in 2020 at Notre Dame when the Irish came in as 15-point favorites and won 12-7.

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First look: Kentucky at Louisville odds and lines

Previewing the Kentucky Wildcats at Louisville Cardinals Week 13 matchup, with college football odds, trends and head-to-head records.

The No. 25 Kentucky Wildcats (8-3, 5-3 SEC) take on the Louisville Cardinals (6-5, 4-4 ACC) at Cardinal Stadium Saturday at 7:30 p.m. ET. Below, we look at the Kentucky at Louisville odds and lines; check back for our college football picks and predictions.

Kentucky is coming off its typical pre-rivalry-week tune-up, a 56-16 win over New Mexico State. The Wildcats had a successful SEC season thanks to a stout run defense (114.5 yards allowed per game; 18th nationally), though they’ve failed to cover in any of their last three conference games.

Louisville’s offense starts and ends with QB Malik Cunningham, who racked up 527 yards of total offense with 7 touchdowns (5 passing, 2 rushing) last week in a 62-22 drubbing of Duke. The Cardinals have the 16th-ranked offense in the country (459.1 yards per game), but they’re giving up 391.8 yards per game on the other side of the ball (77th nationally).

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Kentucky at Louisville odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 6:53 a.m. ET.

Money line: Kentucky +105 (bet $100 to win $105) | Louisville -130 (bet $130 to win $100)
Against the spread (ATS): Kentucky +2.5, -115 (bet $115 to win $100) | Louisville -2.5, 105 (bet $105 to win $100)
Over/Under (O/U): 56.5, O: -112 (bet $112 to win $100) | U: -108 (bet $108 to win $100)

Also see: Betting 101

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2021 betting stats:

ML: Kentucky 8-3 | Louisville 6-5
ATS: Kentucky 7-4 | Louisville 6-5
O/U: Kentucky 7-4 | Louisville 4-7

Kentucky at Louisville head-to-head

This will be the 33rd edition of the Governor’s Cup, with Kentucky holding a slight 17-15 edge all time. Kentucky has won the last two games of this rivalry, though the Wildcats and Cardinals didn’t play in 2020.

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First look: Clemson at Louisville odds and lines

Previewing the Clemson Tigers at Louisville Cardinals Week 10 matchup, with college football odds, trends and head-to-head records.

The Clemson Tigers (5-3, 4-2 ACC) pay a visit to Cardinal Stadium to take on the Louisville Cardinals (4-4, 2-3) Saturday at 7:30 p.m. ET. Below, we look at the Clemson vs. Louisville odds and lines; check back for our college football picks and predictions.

Clemson defeated Florida State 30-20 Saturday. The Tigers defense held the Seminoles to just 241 total yards and a combined 4-for-14 mark on third and fourth downs.

As shaky as the Clemson offense has been this season (114th FBS in total offense), the Tigers have been solid in stopping opponents. Clemson has held foes to 15.3 points per game, which ranks third nationally.

The Cardinals were on the downside of a 28-13 game at NC State Saturday. Louisville now returns home after losing three of its last four games overall. Dating back to 2020, the Cards are 5-1 in their last six home games.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Clemson at Louisville odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 5:52 p.m. ET.

Money line: Clemson -200 (bet $200 to win $100) | Louisville +160 (bet $100 to win $160)
Against the spread (ATS): Clemson -3.5, -112 (bet $112 to win $100) | Louisville +3.5, -108 (bet $110 to win $108)
Over/Under (O/U): 46.5, O: -110 (bet $110 to win $100) | U: -110 (bet $110 to win $100)

Also see: Betting 101

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2021 betting stats:

ML: Clemson 5-3 | Louisville 4-4
ATS: Clemson 1-7 | Louisville 4-4
O/U: Clemson 2-6 | Louisville 2-6

Clemson at Louisville head-to-head

The all-time series is led by the Tigers 6-0. They are 4-0 ATS over the last four meetings (2016-19).

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