Chicago White Sox at Tampa Bay Rays odds, picks and predictions

Analyzing Wednesday’s Chicago White Sox at Tampa Bay Rays odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago White Sox (8-28) and Tampa Bay Rays (19-18) wrap up a 3-game series Wednesday at Tropicana Field. First pitch is scheduled for 6:50 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Rays odds and make our expert MLB picks and predictions for the best bets.

Season series: White Sox lead 3-2

The White Sox suffered a 5-1 loss Tuesday as the Under (7.5) cashed. Chicago has been outscored 13-3 in the 1st 2 games of this series after a surprising 3-game sweep of the Rays at U.S. Cellular Field from April 26-28.

The Rays are back over .500 for the 1st time since April 21 when they were 12-11. Tampa Bay has won a season-high 5 straight games. Its previous high was a 3-game win streak from April 9-12. The Over is 9-5-1 in the past 15 games for the Rays, while going 10-4 in the past 14 outings at Tropicana Field.

White Sox at Rays projected starters

RHP Chris Flexen vs. RHP Aaron Civale

Flexen (1-3, 4.85 ERA) makes his 6th start and 8th appearance. He has a 1.31 WHIP, 3.6 BB/9 and 5.2 K/9 in 29 2/3 IP.

  • Last start: No-decision, 5 IP, 2 ER, 4 H (1 HR), 2 BB, 4 K in 10-5 home loss vs. Minnesota Twins last Wednesday
  • 2024 road splits: 0-1, 2.84 ERA, 12 2/3 IP, 4 ER, 8 H (2 HR), 3 BB, 8 K with .182 opponents’ batting average (OBA) and 0.87 WHIP in 4 starts
  • 2024 vs. Rays: Win, 5 IP, 0 ER, 2 H, 3 BB, 2 K in 9-4 home win on April 26

Civale (2-2, 6.14 ERA) makes his 8th start. He has a 1.34 WHIP, 2.8 BB/9 and 7.2 K/9 in 36 2/3 IP.

  • Last start: No-decision, 4 2/3 IP, 7 ER, 6 H (1 HR), 1 BB, 5 K in 10-8 home win vs. New York Mets Friday
  • 2024 home splits: 1-1, 4.76 ERA, 22 2/3 IP, 12 ER, 19 H (5 HR), 4 BB, 27 K with .226 OBA and 1.01 WHIP in 4 starts
  • 2024 vs. White Sox: No-decision, 4 1/3 IP, 6 ER, 8 H (1 HR), 0 BB, 3 K in 8-7 road loss in 10 innings on April 27

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White Sox at Rays odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:53 a.m. ET.

  • Moneyline (ML): White Sox +180 (bet $100 to win $180) | Rays -225 (bet $225 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-110) | Rays -1.5 (-110)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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White Sox at Rays picks and predictions

Prediction

White Sox 5, Rays 4

Moneyline

The WHITE SOX (+180) are a tempting play for the chance to nearly double up.

Flexen has already beaten Tampa Bay once this season. In fact, it’s the only team he has posted a win against. Meanwhile, Civale has really struggled for the Rays (-225), and there is no way you can consider backing Tampa Bay. He has allowed 5 or more runs in each of his past 3 games, and a total of 22 hits and 6 walks in the span.

The ChiSox already got him once, and confidence is low that he’ll suddenly piece things together.

Run line/Against the spread

If you’re a little more on the conservative side, and you cannot play Chicago straight up, consider the WHITE SOX +1.5 (-110) on the run line instead.

While Chicago is 0-2 on the run line as an underdog in this series, they’re a respectable 7-4 in the past 11 as a ‘dog, with 5 outright wins, including 3 against Tampa Bay, with one of those games started by Flexen.

Over/Under

OVER 8 (-115) is worth playing lightly in the series finale.

The Over holds a 4-3 edge in the past 7 games for the White Sox, while going 11-6 in the 17 games since April 20. Chicago pitching has allowed 5 or more runs in 3 of the past 4 games, and 4 or more runs in 14 of the previous 18 contests.

The Over is 4-2-1 in the past 7 games for Tampa Bay, while cashing at a 10-4 clip in the past 14 under the dome at Tropicana Field.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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