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Florida at Florida State odds, picks and predictions

Analyzing Saturday’s Florida at Florida State odds and lines, with college football expert picks, predictions and best bets.

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The Florida Gators (6-5) meet the Florida State Seminoles (2-9) at Doak S. Campbell Stadium Saturday. Kickoff is scheduled for 7 p.m. ET (ESPN2). Below, we look at Florida vs. Florida State odds from BetMGM Sportsbook’s college football odds and make our expert college football picks and predictions.

The Gators extended their win streak to 2 games, both against ranked teams. They upset No. 16 Ole Miss 23-20 as 13-point home underdogs Nov. 23, with the Under (58) hitting. Florida’s defense forced 3 turnovers, including 2 interceptions from Ole Miss QB Jaxson Dart. Florida QB DJ Lagway threw for 180 yards with 2 TDs and 1 INT, while RB Montrell Johnson Jr. rushed for 107 yards and a TD.

Florida State ended its 6-game losing streak with a 41-7 victory over Charleston Southern Nov. 23, pushing as a 34-point home favorite. The Over (44.5) cashed. Freshman QB Luke Kromenhoek threw for 209 yards with 3 TDs, including 82 yards and a score to WR Ja’Khi Douglas. RB Caziah Holmes contributed with 2 rushing TDs in the win.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Florida at Florida State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 10:15 a.m. ET.

Moneyline (ML): Florida -800 (bet $800 to win $100) | Florida State +550 (bet $100 to win $550)
Against the spread (ATS): Florida -16.5 (-110) | Florida State +16.5 (-110)
Over/Under (O/U): 45.5 (O: -110 | U: -110)

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Florida at Florida State picks and predictions

Prediction

Florida 42, Florida State 13

Moneyline

PASS.

There is no doubt in my mind that Florida (-800) will take this game in Tallahassee, but I’m not betting 1-to-8. I’ll take my wager to the spread.

Against the spread

BET FLORIDA -16.5 (-110).

Florida coach Billy Napier may have saved his job with recent wins over ranked opponents LSU and Ole Miss, and Florida has covered the spread in 7 of its last 8 games.

In contrast, Florida State is having a disastrous season, losing its last 3 games to Power Four teams by more than 20 points. Its win over Charleston Southern snapped a 6-game losing streak, but it’s not exactly a confidence builder. Not only are the Seminoles losing, but they’re getting blown out.

The favorite has won the last 10 meetings between these teams. While Florida State has won 3 of the last 4 at home against the Gators, Florida is the better team and will be eager to extend its dominance in Tallahassee.

Over/Under

BET OVER 45.5 (-110).

Florida has hit the Under in its last 2 games, but both had totals above 55 points. When the line is in the 40s, Florida games have gone Over.

Florida State has also gone Over in its last 2, both with totals in the mid-40s.

The Gators average 27.6 points and 375.7 yards per game, while allowing 25.5 points and 406.3 yards. Florida’s defense struggles against the run, allowing 161.5 rushing yards per game.

While Florida State won’t exploit this as much as an SEC team might, it still highlights Florida’s defensive weaknesses. With the total set below 50, I’m leaning towards the Over.

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Purdue at Indiana odds, picks and predictions

Analyzing Saturday’s Purdue at Indiana odds and lines, with college football expert picks, predictions and best bets.

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The Purdue Boilermakers (1-10, 0-8 Big Ten) take on the No. 10 Indiana Hoosiers (10-1, 7-1) at Memorial Stadium Saturday. Kickoff is set for 6 p.m. ET (FS1). Let’s analyze BetMGM Sportsbook’s college football odds around the Purdue vs. Indiana odds, and make our expert college football picks and predictions.

The Boilers suffered their 10th straight loss last week, 24-17, at Michigan State. They were able to cover the 14-point spread, though. QB Hudson Card was 26-for-47 for 342 yards, 1 TD and 1 INT. However, the team rushed for a combined -4 yards. The Boilermakers are 3-8 ATS and 0-5 straight up on the road this year.

IU is looking to rebound from a 38-15 loss to Ohio State, which really wasn’t anywhere near that close. The Hoosiers failed to cover as 10.5-point dogs. The offense rushed 41 times for 83 yards and was only able to amass 68 yards through the air. RB Ty Son Lawton rushed 15 times for 79 yards and 2 scores.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Purdue at Indiana odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 9:35 a.m. ET.

Moneyline (ML): Purdue +2500 (bet $100 to win $2,500) | Indiana -10000 (bet $10,000 to win $100)
Against the spread (ATS): Purdue +28.5 (-105) | Indiana -28.5 (-115)
Over/Under (O/U): 56.5 (O: -105 | U: -115)

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Purdue at Indiana picks and predictions

Prediction

Indiana 38, Purdue 24

Moneyline

The Hoosiers are going to try to make whatever statement they can here in order to better their chances at getting in the College Football Playoffs.

There is no bet to be made here. The only prop I would consider is for Lawton to score a touchdown, but that’s out of range at -225 as well.

PASS.

Against the spread

Purdue’s record is atrocious, but the squad isn’t hapless. Card can put up some numbers through the air. That’s something IU doesn’t do, and the clock is continuously running because of its rushing attack.

So I like PURDUE +28.5 (-105) with that extra hook to keep it within 28-and-a-hook.

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Over/Under

IU is 8-2 O/U over the last 10, and Purdue is 6-5 O/U on the season. The Over has smashed in 3 of the last 4 meetings.

Again, IU is motivated to score points to impress the judges, and I really like the OVER 56.5 (-105) here.

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Arkansas at Missouri odds, picks and predictions

Analyzing Saturday’s Arkansas at Missouri odds and lines, with college football expert picks, predictions and best bets.

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The Arkansas Razorbacks (6-5, 3-4 SEC) take on the No. 24 Missouri Tigers (8-3, 4-3) at Memorial Stadium/Faurot Field Saturday. Kickoff is set for 3:30 p.m. ET (SEC Network). Let’s analyze BetMGM Sportsbook’s college football odds around the Arkansas vs. Missouri odds, and make our expert college football picks and predictions.

The Razorbacks rolled over Louisiana Tech last week, 35-14, narrowly missing the cover as 23.5-point favorites. QB Taylen Green was 20-for-37 for 221 yards, 2 TDs and 1 INT. He also rushed 6 times for 61 yards and 2 scores. Arkansas is 4-0 against the spread (ATS) on the road this year.

Mizzou bounced back with a 39-20 cover as a 10-point fave against Mississippi State last week. The 39 points were the most the Tigers have scored in 4 games. QB Brady Cook continues to shake off a high-ankle sprain and a thumb injury. He was 15-for-20 for 268 yards, 1 TD and 0 INTs. RB Nate Noel rushed 25 times for 95 yards, and WR Luther Burden III caught 7 balls for 91 yards and 1 TD.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Arkansas at Missouri odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 9:20 a.m. ET.

Moneyline (ML): Arkansas +125 (bet $100 to win $125) | Missouri -150 (bet $150 to win $100)
Against the spread: Arkansas +3 (-110) | Missouri -3 (-110)
Over/Under (O/U): 53.5 (O: -110 | U: -110)

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Arkansas at Missouri picks and predictions

Prediction

Missouri 38, Arkansas 28

Moneyline

It’s Senior Day at Mizzou, and this will be the final home game for the trio of Cook, Noel and Burden. Cook and Noel are seniors, and the junior Burden is likely to be a high NFL draft pick. Cook is playing through a high-ankle sprain because his time at Mizzou is coming to a close. So, do you think there is any chance he’s not going to leave it all on Faurot Field?

Mizzou wins, but I’m going to the spread instead.

Take BRADY COOK OVER 230.5 PASSING YARDS (-115). He’s going to leave his mark in his final home game.

Against the spread

I like MISSOURI -3 (-110) here. I know, Arkansas has covered in each road game this year. But this means something to Cook and the Tigers, who had much higher aspirations for their season before the injury bug bit them.

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Over/Under

Arkansas has cashed Overs in 3 of 4, and Mizzou has done so in 2 of 3. The schools have seen the Over cash in 3 of 4 matchups. This is a bit of a stout number to hit. However, Mizzou just dropped 39 last week and has motivation on its side, and Arkansas has scored 45, 31 and 58 in 3 of its last 4.

Take the OVER 53.5 (-110).

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Arizona State at Arizona odds, picks and predictions

Analyzing Saturday’s Arizona State at Arizona odds and lines, with college football expert picks, predictions and best bets.

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The No. 15 Arizona State Sun Devils (9-2, 6-2 Big 12) face the Arizona Wildcats (4-7, 2-6) Saturday in the battle for the Territorial Cup. Kickoff from Arizona Stadium is at 3:30 p.m. ET (FOX). Below, we look at Arizona State vs. Arizona odds from BetMGM Sportsbook’s college football odds and make our expert college football picks and predictions.

The Sun Devils notched their fourth consecutive overall win and second straight victory over a ranked opponent, defeating No. 20 BYU 28-23 Nov. 23. Arizona State covered as a 3.5-point home favorite, powered by a standout performance from RB Cam Skattebo, who carried the ball 28 times for 147 yards and 3 TDs. QB Sam Leavitt delivered 247 passing yards, with WR Jordyn Tyson accounting for 125 of those in a dynamic aerial showing.

The Wildcats dropped their sixth game in 7 outings, losing 49-28 at TCU Nov. 23. Arizona couldn’t cover as a 10.5-point underdog, with the Over (60) hitting comfortably. The defense gave up 450 total yards, including 303 through the air. QB Noah Fifita passed for 284 yards with 2 TDs, both caught by WR Chris Hunter. WR Tetairoa McMillan stood out with 9 catches for 115 yards, despite the team’s struggles on both sides of the ball.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Arizona State at Arizona odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 9:05 a.m. ET.

Moneyline (ML): Arizona State -300 (bet $300 to win $100) | Arizona +250 (bet $100 to win $250)
Against the spread (ATS): Arizona State -8.5 (-105) | Arizona +8.5 (-115)
Over/Under (O/U): 53.5 (O: -110 | U: -110)

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Arizona State at Arizona picks and predictions

Prediction

Arizona State 31, Arizona 13

Moneyline

PASS.

Arizona State (-300) is in the College Football Playoff hunt but must avoid a slip-up against rival Arizona. With the moneyline at 1-to-3, it’s not worth the risk — I’ll place my wager on the spread instead.

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Against the spread

BET ARIZONA STATE -8.5 (-105).

The Sun Devils are riding high, posting an impressive 8-2 straight up and ATS record in their last 10 games. Facing rival Arizona, the Sun Devils have everything to lose as they chase a potential College Football Playoff berth.

Arizona, despite a poor season, will look to disrupt Arizona State’s momentum, but the odds are stacked against it. Arizona State has won its last 8 games as a favorite and covered the spread in 6 straight while laying points.

The Sun Devils are ranked 16th nationally but could vault into playoff contention with 2 more wins, starting with this rivalry. Arizona’s struggling defense, especially against the run, will have a tough time containing Skattebo, who has surpassed 1,200 rushing yards this season.

Arizona lacks the offensive firepower to keep pace, and with everything on the line, expect Arizona State to stay focused and take care of business.

Over/Under

BET UNDER 53.5 (-110).

While trends point towards the Over, with the last 4 meetings going Over and both teams hitting the Over in 3 of their last 4 games, Arizona’s offense has been lackluster all season. Coach Brent Brennan expressed disappointment after its loss to TCU, showing the team’s struggles.

Arizona State’s games have averaged 53.4 points, with a 6-5 O/U record. The Sun Devils are 7-2 to the Under following a home win and 11-4 to the Under after playing on the road, suggesting a lower-scoring affair is more likely.

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Cal at SMU odds, picks and predictions

Analyzing Saturday’s Cal at SMU odds and lines, with college football expert picks, predictions and best bets.

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The Cal Golden Bears (6-5, 2-5 ACC) and No. 9 SMU Mustangs (10-1, 7-0) meet Saturday. Kickoff from Gerald J. Ford Stadium in Dallas is scheduled for 3:30 p.m. ET (ESPN2). Let’s analyze BetMGM Sportsbook’s college football odds around the Cal vs. SMU odds, and make our expert college football picks and predictions.

Cal picked up a 24-21 win over rival Stanford in the Big Game Nov. 23 in Berkeley, but it came nowhere near covering as a 14.5-point favorite while the Under (53.5) cashed. Cal has won 3 of the past 4 games to attain bowl eligibility, but it has failed to cover in consecutive outings for the first time this season. The Under is 1-0-1 in the past 2 games after a 3-0 run to the Over.

SMU posted a 33-7 win at Virginia as an 11-point favorite Saturday while the Under (54.5) cashed. The Mustangs have won 8 in a row, while going 6-2 against the spread (ATS). The Over is 3-1 in the past 4 games, while going 6-2 in the previous 8 outings.

Rankings – US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Cal at SMU odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 8:45 a.m. ET.

Moneyline (ML): Cal +400 (bet $100 to win $400) | SMU -550 (bet $550 to win $100)
Against the spread: Cal +13.5 (-110) | SMU -13.5 (-110)
Over/Under (O/U): 55.5 (O: -105 | U: -115)

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Cal at SMU picks and predictions

Prediction

SMU 32, Cal 22

Moneyline

SMU (-550) will cost you 5½ times your potential return, and that’s way too much risk for not nearly enough reward. Even as part of a multi-team parlay, that’s not a recommended play.

SMU can secure a spot in the College Football Playoff with a win in this game and a victory in the ACC Championship Game, but it cannot take its foot off the gas.

PASS.

Against the spread

Play CAL +13.5 (-110) catching nearly 2 TDs in the Metroplex as it closes out its first season of ACC play.

The Golden Bears have been exciting on offense lately, going for 23 or more points in 5 straight games, while the defense has allowed 21 or more points in 3 in a row.

Cal will need that offense to be on point, as SMU -13.5 (-110) has been good for 28 or more points in 8 consecutive outings.

Over/Under

OVER 55.5 (-105) might be the best play on the board.

The Mustangs have cashed high in 3 of the past 4 outings and 6 of the previous 8 contests. They roll up 444.3 total yards per game, and 39.3 points per game, with a balanced attack led by dual-threat QB Kevin Jennings.

The Golden Bears have hit the Over at a 3-1-1 clip in the past 5 outings, and they have the offense to at least keep the Mustangs somewhat close in a high-scoring affair.

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Miami at Syracuse odds, picks and predictions

Analyzing Saturday’s Miami at Syracuse odds and lines, with college football expert picks, predictions and best bets.

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The No. 7 Miami Hurricanes (10-1, 6-1 ACC) pay a visit to the Syracuse Orange (8-3, 4-3) in the 2024 regular-season finale Saturday. Kickoff from the JMA Wireless Dome is set for 3:30 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s college football odds around the Miami vs. Syracuse odds, and make our expert college football picks and predictions.

Miami, which is No. 7 in the US LBM Coaches Poll, enters after demolishing the Wake Forest Demon Deacons 42-14 Nov. 23 while covering as a 23.5-point favorite. The Hurricanes put up 508 yards of offense and their defense held strong, allowing just 193 yards and forcing 2 turnovers in the win. Miami really ran up the score in the fourth quarter, scoring 21 points while holding Wake Forest scoreless.

Syracuse picked up a 31-24 win over the UConn Huskies Nov. 23 as a 10-point favorite. QB Kyle McCord threw for an astounding 470 yards and 2 TDs as WR Darrell Gill Jr. hauled in 9 receptions for 177 yards to lead the Orange in receiving yards. The Orange have put up at least 30 points in all of their last 3 wins.

– US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Miami at Syracuse odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 8:25 a.m. ET.

Moneyline (ML): Miami -450 (bet $450 to win $100) | Syracuse +325 (bet $100 to win $325)
Against the spread (ATS): Miami -10.5 (-110) | Syracuse +10.5 (-110)
Over/Under (O/U): 67.5 (O: -105 | U: -115)

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Miami at Syracuse picks and predictions

Prediction

Miami 42, Syracuse 35

Moneyline

PASS.

The Hurricanes are the more talented team and have a very dominant offense, so they will pick up the win and cover here as -450 favorites. Pass here, and bet the spread and/or total instead.

Against the spread

LEAN SYRACUSE +10.5 (-110).

Miami’s defense allows 22.3 opponent points per game (PPG). Pair that with a Syracuse offense that scores over 30 a game and averages over 450 yards, and you can see that Syracuse is simply too good to expect this game to be a blowout.

Syracuse and Miami are very similar statistically, and Miami has had a few close calls this season, so the Orange are a safe bet to cover here.

This is a lean because the ATS numbers for these squads have been very similar this season.

Over/Under

BET OVER 67.5 (-105).

The Over has hit in 3 of Syracuse’s last 4 this season and is 2-0 in its last 2 home games. For Miami, the Over is 2-1 in its last 3 road games and 7-3-1 for the Hurricanes this season.

Miami and Syracuse average 44.7 and 31.7 PPG, respectively, so the Over is nearly a lock to hit.

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Maryland at Penn State odds, picks and predictions

Analyzing Saturday’s Maryland at Penn State odds and lines, with college football expert picks, predictions and best bets.

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The Maryland Terrapins (4-7, 1-7 Big Ten) pay a visit to the No. 4 Penn State Nittany Lions (10-1, 7-1) Saturday. Kickoff from Beaver Stadium is set for 3:30 p.m. ET (Big Ten Network). Let’s analyze BetMGM Sportsbook’s college football odds around the Maryland vs. Penn State odds, and make our expert college football picks and predictions.

Maryland lost 29-13 as 4.5-point home underdogs to the Iowa Hawkeyes last Saturday with the Over (41) hitting. Maryland was held scoreless up until the 5:57 mark of the third quarter. The Terrapins have lost 4 straight, going 1-3 against the spread (ATS) and haven’t scored more than 18 points in each of their last 3 games.

Penn State scraped by the Minnesota Golden Gophers 26-25 Saturday and wasn’t even close to covering as an 11.5-point road favorite with the Over (45) cashing. The Golden Gophers possessed the ball for 8-plus more minutes than the Nittany Lions, but Minnesota was unable to capitalize on 2 PSU turnovers. Penn State QB Drew Allar finished with 244 passing yards and 2 TDs (1 by air, 1 on the ground). He also steered a key 12-play, 72-yard drive — including 2 fourth-down conversions — on the final possession to run the clock out.

Rankings – US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Maryland at Penn State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 4:45 a.m. ET.

Moneyline (ML): Maryland +1500 (bet $100 to win $1,500) | Penn State -5000 (bet $5,000 to win $100)
Against the spread: Maryland +24.5 (-110) | Penn State -24.5 (-110)
Over/Under (O/U): 50.5 (O: -110 | U: -110)

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Maryland at Penn State picks and predictions

Prediction

Penn State 41, Maryland 7

Moneyline

AVOID.

Penn State (-5000) will win, but betting such a heavy favorite is never worth the risk. PASS and bet on the spread and/or O/U instead.

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Against the spread

BET PENN STATE -24.5 (-110).

Penn State is 2-1 ATS in its last 3 games, while Maryland has failed to cover in each of its last 2 games and is 2-6 ATS in its last 8 games.

The Nittany Lions have won and covered the spread in the last 3 meetings in this series, and is 7-3 ATS in its last 10 head-to-head matchups.

After allowing Minnesota to keep things close in their last outing, the Nittany Lions will be extra motivated to make sure they blow out the Terrapins.

Over/Under

BET UNDER 50.5 (-115).

The Under has hit in 2 of Maryland’s last 3 games and is 5-0 in Penn State’s last 5 home games. The Under has also hit in 5 of the last 6 Maryland-Penn State matchups and is 7-3 in the last 10 meetings.

Be aware that the Over is 8-3 for Maryland this season, while it’s 4-7 for Penn State.

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Illinois at Northwestern odds, picks and predictions

Analyzing Saturday’s Illinois at Northwestern odds and lines, with college football expert picks, predictions and best bets.

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The No. 25 Illinois Fighting Illini (8-3, 5-3 Big Ten) and Northwestern Wildcats (4-7, 2-6) meet Saturday. Kickoff from Wrigley Field is scheduled for noon ET (Big Ten Network). Let’s analyze BetMGM Sportsbook’s college football odds around the Illinois vs. Northwestern odds, and make our expert college football picks and predictions.

Illinois leads the all-time series 57-55-5, with the Wildcats taking last season’s meeting in Champaign in a wild 45-43 shootout. While the Illini have won 2 of the past 3 in the series, including a 41-3 rout in Evanston Nov. 26, 2022, Northwestern is 7-2 straight up (SU) and 6-3 against the spread (ATS) in the past 9 installments.

Illinois has rolled up wins against Michigan State and Rutgers in the past 2 weekends, scoring 38 points in each game, to secure 8 wins and a solid bowl game in the Big Ten. The Over has cashed in each of the 2 outings. While Illinois is just 2-2 SU in 4 road games, it is a solid 3-1 ATS while splitting the Over/Under (O/U).

Northwestern has struggled this season, and it was manhandled 50-6 at Michigan last weekend, ending any faint hopes of bowl eligibility. The Wildcats have dropped 4 of the past 5 games, although they’ve covered 2 of the past 3outings. The Over is 3-1 in the past 4 games and 5-2 across the past 7 contests.

Rankings – US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Illinois at Northwestern odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 11 p.m. ET.

Moneyline (ML): Illinois -300 (bet $300 to win $100) | Northwestern +240 (bet $100 to win $240)
Against the spread: Illinois -8 (-110) | Northwestern +8 (-110)
Over/Under: 43.5 (O: -115 | U: -105)

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Illinois at Northwestern picks and predictions

Prediction

Illinois 19, Northwestern 12

Moneyline

Illinois (-300) will cost you 3 times your potential return, and that’s way too much in this rivalry game which Northwestern (+240) has dominated in recent seasons.

PASS.

Against the spread

Back NORTHWESTERN +8 (-110) to keep this within 1 score.

The Wildcats have had a pretty good defense, for the most part, but Northwestern has struggled to score points. It should be able to throw a blanket on Illinois -8 (-110), keeping the Illini within 1 score.

Over/Under

UNDER 43.5 (-105) is a low number, but it’s the best play in this game.

Temperatures will be in the mid-20s for this game, and winds will be sustained at 12-14 mph, making for a very raw days in Wrigleyville at this time of year, even if they’re blowing out of the west.

Points are going to be at a premium in this Big Ten finale in Wrigleyville.

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Michigan at Ohio State odds, picks and predictions

Analyzing Saturday’s Michigan at Ohio State odds and lines, with college football expert picks, predictions and best bets.

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The Michigan Wolverines (6-5, 4-4 Big Ten) and No. 2 Ohio State Buckeyes (10-1, 7-1) meet Saturday. Kickoff from Ohio Stadium is scheduled for noon ET (FOX). Let’s analyze BetMGM Sportsbook’s college football odds around the Michigan vs. Ohio State odds, and make our expert college football picks and predictions.

Michigan leads the all-time series 61-51-6, with the Wolverines winning the previous 3 meetings, including a 45-23 win Nov. 26, 2022, in the most recent battle in Columbus.

The Wolverines won the national championship last season, but fell on hard times in 2024 after coach Jim Harbaugh bolted for the NFL.

Michigan is bowl eligible after scoring a season-high in points during a 50-6 win over Northwestern last weekend, and the defense has allowed 20 or fewer points in 3 of the previous 4 outings. The Wolverines are 3-1 against the spread (ATS) in those 4 games.

Ohio State scored a massive 38-15 win over Indiana last weekend in a top-5 showdown in Columbus, its third such game of the season. The Buckeyes can clinch a spot in the Big Ten Championship game, and a rematch against Oregon, with a victory Saturday. The Buckeyes are also 3-1 ATS in the past 4 outings.

Rankings – US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

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Michigan at Ohio State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 10 p.m. ET.

Moneyline (ML): Michigan +750 (bet $100 to win $750) | Ohio State -1200 (bet $1,200 to win $100)
Against the spread: Michigan +19.5 (-105) | Ohio State -19.5 (-115)
Over/Under (O/U): 42.5 (O: -105 | U: -115)

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Michigan at Ohio State picks and predictions

Prediction

Ohio State 29, Michigan 16

Moneyline

Ohio State (-1200) will cost you 12 times your potential return, and that’s way too much risk and not enough reward, especially in a rivalry game. You can’t touch this, even as part of a multi-leg parlay.

PASS.

Against the spread

Roll with MICHIGAN +19.5 (-105), as even the most ardent Ohio State -19.5 (-115) fan knows this is too many points in one of the best rivalries in America.

While Buckeyes fans can hope that they cover, snapping a 3-game skid in the series, the Wolverines have had their number in previous seasons. There will be a ton of emotions early in the game, and Ohio State hasn’t been getting off to great starts in these big outings. It fell behind Indiana early, it fell behind Penn State early, heck, it even fell behind Northwestern early at Wrigley Field.

Over/Under

OVER 42.5 (-105) is the lean, but go lightly.

Woody Hayes and Bo Schembechler would be rolling over in their graves if they saw the Over is 10-0 in the past 10 meetings in this rivalry game. The winner has scored 42 points in 4 of the past 5 meetings, and the winner has notched 30 or more in each of the previous 10 installments.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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South Carolina at Clemson odds, picks and predictions

Analyzing Saturday’s South Carolina at Clemson odds and lines, with college football expert picks, predictions and best bets.

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The No. 14 South Carolina Gamecocks (8-3) and the No. 12 Clemson Tigers (9-2) meet at Memorial Stadium Saturday. Kickoff is slated for noon ET (ESPN). Below, we look at South Carolina vs. Clemson odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

South Carolina secured its fifth consecutive win with a commanding 56-12 triumph over Wofford Nov. 23. The Gamecocks amassed 608 total yards, including 343 through the air and 265 on the ground. QB LaNorris Sellers threw for 307 yards with 3 TDs and 1 INT while rushing for 53 yards and a score. On defense, South Carolina dominated, holding Wofford to a mere 28 rushing yards while stifling any offensive rhythm from the Terriers.

Clemson earned its third consecutive victory, cruising past the Citadel Bulldogs 51-14 Nov. 23. QB Cade Klubnik tossed for 198 yards with 3 TDs, while RB Jay Haynes rushed for 118 yards and 2 scores. WR Antonio Williams contributed 5 catches for 72 yards and 2 TDs. Despite the dominant win, the Tigers struggled defensively, allowing 288 rushing yards to the Bulldogs.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

South Carolina at Clemson odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 2:50 p.m. ET.

Moneyline (ML): South Carolina +125 (bet $100 to win $125) | Clemson -150 (bet $150 to win $100)
Against the spread (ATS): South Carolina +3 (-110) | Clemson -3 (-110)
Over/Under (O/U): 49.5 (O: -105 | U: -115)

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South Carolina at Clemson picks and predictions

Prediction

South Carolina 24, Clemson 21

Moneyline

BET SOUTH CAROLINA (+125).

The Gamecocks have one of their strongest teams in recent years, as well as the potential to win this game on the road.

Clemson is 1-4 ATS in its last 5 games, while South Carolina has covered 5 of its last 6.

The Gamecocks come into this matchup riding a 5-game winning streak, showing strong momentum and the ability to perform when it matters. South Carolina’s defense has been outstanding, ranking 12th in FBS in scoring defense (18.8 points allowed per game) and 19th against the run, allowing just 110.9 yards per game.

This will be crucial against a Clemson team that relies on its running game with Klubnik and RB Phil Mafah. The Gamecocks’ defense is well-equipped to slow down Clemson’s ground game and force it into more predictable situations.

On offense, South Carolina has a balanced attack with a solid rushing game, ranked 4th in the SEC, led by RB Raheim “Rocket” Sanders with 821 yards and 11 TDs. Sellers has also been efficient and is ranked 25th nationally in passer rating. South Carolina’s versatility presents challenges for Clemson’s defense, which has had occasional struggles.

Against the spread

PASS.

I’m all about getting those plus odds on the moneyline, but if you want to play it safe and take the field goal, I won’t fault you.

Over/Under

BET UNDER 49.5 (-115).

Clemson’s offense has been inconsistent, despite ranking 11th in scoring offense (36.3 points per game). While it has faced weaker defenses, South Carolina’s defense should be more effective at limiting big plays. Clemson has hit the Under in 6 of its last 8 games.

Both teams favor a slow, methodical style of play, relying on defense and ball control rather than high-scoring affairs. South Carolina’s strong run game complements its defense.

With both teams focused on avoiding mistakes in a high-stakes matchup, this game is likely to stay under the total. Expect a typical SEC-ACC showdown, marked by defensive battles and a clock-controlling approach. Take the Under for this one.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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