Syracuse at Florida State odds, picks and predictions

Analyzing Saturday’s Syracuse at Florida State odds and lines, with college football expert picks, predictions and best bets.

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The Syracuse Orange (4-2, 0-2 ACC) visit the 4th-ranked Florida State Seminoles (5-0, 3-0) on Saturday. Kickoff from Doak Campbell Stadium is set for noon E.T. (ABC). Below, we analyze BetMGM Sportsbook’s lines around the Syracuse vs. Florida State odds, and make our expert college football picks and predictions.

Syracuse was blown out 40-7 by the North Carolina Tar Heels last week while failing to cover as a 9.5-point road underdog. QB Garrett Shrader went 15 of 21 for 124 yards and an INT while RB LeQuint Allen had the only Orange TD. The Syracuse defense had no answers for UNC QB Drake Maye, who threw for 442 yards and 3 TDs.

Florida State took down Virginia Tech 39-17 last week while failing to cover as a 23.5-point home favorite. QB Jordan Travis threw for 170 yards and 2 TDs while RB Trey Benson ran the ball 11 times for 200 yards and 2 TDs. In total, the Seminoles had 282 rushing yards for 3 TDs.

Florida State is No. 4 in the US LBM Coaches Poll powered by USA TODAY Sports.

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Syracuse at Florida State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 11:35 p.m. ET.

  • Moneyline (ML): Syracuse +575 (bet $100 to win $575) | Florida State -900 (bet $900 to win $100)
  • Against the spread (ATS): Syracuse +17.5 (-110) | Florida State -17.5 (-110)
  • Over/Under (O/U): 54.5 (O: -115 | U: -105)

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Syracuse at Florida State picks and predictions

Prediction

Florida State 37, Syracuse 21

Moneyline

PASS.

There is no money to be made betting on Florida State at -900. They are a justifiable heavy favorite in this matchup after a poor performance from Syracuse last week. This should be an easy victory for the Seminoles. At best, include the Florida State ML in a parlay to increase your odds for an easy leg.

Against the spread

LEAN SYRACUSE +17.5 (-110).

While Florida State is the clear favorite, it has not had a dominant win in the past 3 weeks and is just 1-3 ATS in its last 4 games as a double-digit favorite. The Seminoles defense has been their biggest liability this season and that is what will keep Syracuse in this game enough to cover the spread.

Over/Under

BET UNDER 54.5 (-105).

Syracuse is just 1-4 on Overs this season while only scoring 21 combined points in the last 2 games. The Seminoles have not scored more than 39 points in any of their last 3 games and have played closer games of late resulting in the Under hitting at a higher rate.

The Under is also 1-5 in the last 6 meetings between these programs dating back to 2016.

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