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The San Diego Padres (81-62) welcome the San Francisco Giants (69-73) to PETCO Park Saturday for the 2nd game of their 3-game series. First pitch is set for 8:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Giants vs. Padres odds and make our expert MLB picks and predictions for the best bets.
Season series: Tied 4-4
The Giants lost the series-opening game 5-1 Friday, closing as a +180 underdog. San Francisco has now lost 5 of its last 6 games, falling to 4th in the NL West. It is 29-41 on the road this season and 66-76 against the spread (ATS). The Giants have lost 2 of 3 in their 2 series prior.
The Padres have been the opposite, winning 4 of their last 5 games. They beat the Detroit Tigers in 2 of 3 the series prior. San Diego has won 8 of its last 12. It is 40-33 at home and is 4-1 over its last 5 at home. The Padres are 73-70 ATS on the season.
Giants at Padres projected starters
RHP Logan Webb vs. RHP Dylan Cease
Webb (11-9, 3.43 ERA) makes his 30th start. He has a 1.20 WHIP, 2.2 BB/9 and 7.5 K/9 through 183 2/3 innings.
- Last start: Loss, 6 IP, 6 ER, 8 H, 0 BB, 4 K in 7-5 home loss to the Miami Marlins Sunday
- 2024 away stats: 4-5, 4.29 ERA (86 IP, 41 ER), 1.44 WHIP, 8.3 K/9 in 15 starts
- Career vs. Padres: 3-2, 2.55 ERA (70 2/3 IP, 20 ER), 1.12 WHIP, 7.4 K/9 in 12 appearances (11 starts)
Cease (12-10, 3.62 ERA) makes his 30th start. He has a 1.09 WHIP, 3.2 BB/9 and 11.0 K/9 through 164 innings.
- Last start: No-decision, 5 IP, 3 ER, 2 H, 3 BB, 4 K in 4-3 road win over the Tampa Bay Rays Sunday
- 2024 home stats: 5-6, 3.14 ERA (71 2/3 IP, 25 ER), 1.07 WHIP, 11.8 K/9 in 12 starts
- Career vs. Giants: 2-1, 2.61 ERA (20 2/3 IP, 6 ER), 1.11 WHIP, 10.9 K/9 in 4 starts
Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.
Giants at Padres odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:50 a.m. ET.
- Moneyline (ML): Giants +130 (bet $100 to win $130) | Padres -154 (bet $154 to win $100)
- Run line (RL)/Against the spread (ATS): Giants +1.5 (-184) | Padres -1.5 (+152)
- Over/Under (O/U): 7 (O: -110 | U: -110)
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Giants at Padres picks and predictions
Prediction
Giants 5, Padres 3
Moneyline
BET GIANTS (+130).
The Giants have their ace on the mound, and Webb has been a strong starting option for San Francisco. The Giants are 5-2 in Webb’s last 7 starts. The Giants are 40-32 following a loss as well, which they are here.
The Padres have played well over the last week but are just 5-4 over their last 9 games. They have tallied 4 or fewer in 6 of those 9 games as well. For the value here, take GIANTS (+130).
Run line/Against the spread
PASS.
There’s no great value here. The Giants are too expensive as a run-line underdog while the home-side Padres are too risky as a run-line favorite. Avoid this play.
Over/Under
BET OVER 7 (-110).
The Giants have gone Over in Webb’s last 3 starts and are 3-2 O/U in their last 5 games. They have scored at least 4 in 3 of their last 5 and have allowed at least 6 in 3 of those as well.
San Francisco is 71-65-6 O/U this season. The Padres are 3-3-1 O/U in their last 7 games and are 76-64-3 O/U this season. Considering those trends, take OVER 7 (-110).
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