San Francisco Giants at Pittsburgh Pirates odds, picks and predictions

Analyzing Wednesday’s San Francisco Giants at Pittsburgh Pirates odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (23-26) and Pittsburgh Pirates (23-26) play the 2nd game of a 3-game series at PNC Park Wednesday. First pitch is scheduled for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Pirates odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 2-2

The Giants snapped a 4-game winning streak Tuesday with a 7-6 loss in 10 innings against Pittsburgh while failing to cash as -129 road favorites. San Francisco led 6-2 after 8 innings but allowed 4 runs in the bottom of the 9th and the game-winning run in the 10th. LHP Erik Miller was credited with the loss.

Pittsburgh has won back-to-back games after taking down San Francisco Tuesday and cashing as a +119 home underdog. Pirates 2B Nick Gonzalez walked it off in the 10th with a run-scoring single.

Giants at Pirates projected starters

LHP Blake Snell vs. RHP Jared Jones

Snell (0-3, 11.57 ERA) makes his 4th start. He has a 1.97 WHIP, 3.9 BB/9 and 9.3 K/9 in 11 2/3 innings.

  • Has been out since April 19 (adductor strain)
  • Has allowed 15 ER and 2 HR this season while striking out 12 and walking 5

Jones (3-4, 2.89 ERA) makes his 10th start. He has a 0.91 WHIP, 1.2 BB/9 and 10.7 K/9 in 53 innings.

  • Pirates are 4-5 in his starts, including 2-1 in his last 3
  • Has allowed 3 or fewer ER in each start
  • Has allowed 17 ER and 9 HR while striking out 63 and walking 7

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Giants at Pirates odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:17 a.m. ET.

  • Moneyline (ML): Giants +100 (bet $100 to win $100) | Pirates -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-225) | Pirates -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: +100 | U: -120)

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Giants at Pirates picks and predictions

Prediction

Pirates 5, Giants 4

Moneyline

BET PIRATES (-120).

The Pirates are 4-1 in their last 5 games and have scored 5 or more runs in 3 of their last 5 while allowing 3 or fewer in 3 of their last 4. They face Snell who struggled mightily before his injury and is seeing his 1st action in over a month.

Run line/Against the spread

PASS.

There is no value on the run line.

Over/Under

BET OVER 7.5 (+100).

The Giants have scored 6 or more runs in 3 of their last 4 games and hit the Over in 6 of their last 8. Pittsburgh has scored 5 or more runs in 3 of its last 5 games and also hit the Over in 6 of its last 10. While Jones has been outstanding for the Pirates on the mound this season, expect the game to surpass the low total of 7.5 runs.

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