New York Mets at San Francisco Giants odds, picks and predictions

Analyzing Friday’s New York Mets at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The New York Mets (13-7) and San Francisco Giants (6-12) continue a 4-game series at Oracle Park Friday. First pitch is at 10:15 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Mets vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Mets lead 1-0

New York won Thursday’s series opener 9-4. The Mets have gone 6-1 with an .827 OPS on their current road trip that included previous stops at the Oakland Athletics and Los Angeles Dodgers.

San Francisco is back at home after a 1-4 road trip at the Detroit Tigers and Miami Marlins. The Giants are 3-9 with a .667 OPS over their last 12 outings.

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Mets at Giants projected starters

LHP Joey Lucchesi vs. RHP Anthony DeSclafani

Lucchesi is making his 1st MLB appearance since undergoing Tommy John surgery in June 2021.

  • Has a 4.24 ERA over 66 starts and 4 relief appearances in his career
  • Has made 3 starts at Triple-A this April: 15 2/3 IP, 4 ER, 11 H, 7 BB, 15K

DeSclafani (1-0, 1.42 ERA) is tabbed for his 4th start this season. He has a 0.63 WHIP, 0.0 BB/9 and 7.6 K/9 through 19 IP.

  • Owns a 2.95 ERA at Oracle Park over the last 3 seasons (2021-23)
  • Faces a left-leaning New York nine: career vs. left-handed batters .812 OPS allowed, vs. right-handed batters .651 OPSA

Mets at Giants odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:15 p.m. ET.

  • Moneyline: Mets +100 (bet $100 to win $100) | Giants -118 (bet $100 to win $118)
  • Run line (RL)/Against the spread (ATS): Mets -1.5 (+162) | Giants +1.5 (-196)
  • Over/Under (O/U): 8.5 (O: -120 | U: -102)

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Mets at Giants picks and predictions

Prediction

Giants 6, Mets 4

Moneyline

Analytics support numbers would say the Mets have been fortunate with their run-scoring and run-prevention numbers so far. Add in a weak New York schedule so far, and there is some lean on the Giants here. However, just go with a partial unit on SAN FRANCISCO (-118) due to Lucchesi being very much an unknown quantity.

Run line/Against the spread

Avoid the juice here: PASS.

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Over/Under

The Over is 5-0-1 in the last 6 meetings in this series. With a 10 mph wind helping the batters in this one and with some serious fade to New York’s pitching numbers, consider a partial-unit play on the OVER 8.5 (-120).

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