The Indianapolis Colts travel Saturday to Orchard Park, NY, for their first action in the Shane Steichen era. The Buffalo Bills host the Colts at Highmark Stadium for a preseason Week 1 game.
With so many new faces and schemes still being installed, there is a lot to work out, but perhaps the most exciting part: Colts football is back.
Here are the five things to know for Week 1 of the preseason: