Arizona Cardinals at Tennessee Titans odds, picks and predictions

Analyzing Saturday’s Arizona Cardinals at Tennessee Titans odds and lines, with expert NFL picks, predictions and best bets.

The Arizona Cardinals (1-1) and Tennessee Titans (1-1), after holding a joint practice with each other on Wednesday, close out the preseason with Saturday’s kickoff set for 7 p.m. ET at Nisson Stadium in Nashville. Below, we analyze Tipico Sportsbook‘s lines around the Cardinals vs. Titans odds, and make our best NFL picks, predictions and bets.

The Cardinals beat the Cincinnati Bengas 36-23 in their preseason opener,  and followed that up with a 24-17 loss to the Baltimore Ravens. They have not played their starters yet in the preseason and will not play their starters in the finale against the Titans. QB Trace McSorley will start for the Cardinals and play into the 2nd half, while undrafted rookie QB Jarrett Guarantano will close things out.

The Titans are also expected to keep their starters out of the game, giving rookie QB Malik Willis the opportunity to get game reps. After a 23-10 loss to the Ravens in their preseason opener, they beat the Tampa Bay Buccaneers 13-3 last week.

Cardinals at Titans odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 3:22 p.m. ET.

  • Money line (ML): Cardinals +133 (bet $100 to win $133) | Titans -165 (bet $165 to win $100)
  • Against the spread (ATS): Cardinals +3.5 (-135) | Titans -3.5 (+110)
  • Over/Under (O/U): 35.5 (O: -110 | U: -110)

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Cardinals at Titans picks and predictions

Prediction

Cardinals 24, Titans 17

Money line

Both teams are 1-1 this preseason and have not been playing their starters. The absence of starters creates highly variant potential outcomes.

If one team were playing its starters in this game, the pick would be easier, but without that, the best bet on a preseason game is to go with the best value, as backups and players battling to have an NFL job against each other is really a tossup. Take the CARDINALS (+133).

Against the spread

PASS on the spread. This is only because it is a preseason game. Both teams are 1-1 ATS in the preseason.

The Cardinals blew out the Titans in the regular season last year 38-13 in Week 1 and have won their only other preseason road game.

However, again, preseason games that don’t involve starters are tossups. You go with the best value. That is the money line in this case.

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Over/Under

The Cardinals’ 2 preseason games have had totals of 41 and 59 points. The Titans’ highest total was 33 points.

Arizona’s defense has allowed both preseason opponents to reach the 20s. The Titans haven’t scored more than 13 points in a game this preseason.

Are the Titans going to struggle to score again or will they be able to put points on the board as both of Arizona’s opponents have done?

I LEAN OVER 35.5 (-110).

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Los Angeles Rams at Cincinnati Bengals odds, picks and predictions

Analyzing Saturday’s Los Angeles Rams at Cincinnati Bengals odds and lines, with expert NFL picks, predictions and best bets.

The final week of the preseason includes a matchup between the 2  participants in Super Bowl 56 six months ago, the Los Angeles Rams (1-1) and Cincinnati Bengals (0-2). They’ll square off at Paycor Stadium in Cincinnati on Saturday, with kickoff set for 6 p.m. ET. Below, we analyze Tipico Sportsbook‘s lines around the Rams vs. Bengals odds, and make our best NFL picks, predictions and bets.

The Rams went 0-3 in the preseason last year, but they come into this game 1-1 after beating the Los Angeles Chargers in the opener 29-22 and losing to the Houston Texans 24-20 in Week 2. Their record should be taken with a grain of salt because they haven’t played any of their starters – nor will they on Saturday against the Bengals.

The Bengals are 0-2 after losing 25-22 to the New York Giants and 36-23 to the Arizona Cardinals. Like the Rams, they’ve taken a cautious approach to the preseason, only playing their backups and protecting their top players from injury. That’ll be the case on Saturday, too, especially after they got in 2 days of practice with the Rams on Wednesday and Thursday.

Rams at Bengals odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 3:21 p.m. ET.

  • Money line (ML): Rams +115 (bet $100 to win $115) | Bengals -140 (bet $140 to win $100)
  • Against the spread (ATS): Rams +2.5 (-103) | Bengals -2.5 (-117)
  • Over/Under (O/U): 37.5 (O: -115 | U: -105)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Rams at Bengals picks and predictions

Prediction

Rams 23, Bengals 20

Money line

Aside from some poor play up front, the Rams offense has actually looked pretty good in the preseason, especially with QB Bryce Perkins under center. QB John Wolford‘s status is unclear after he suffered a thumbnail injury on his right hand, so it could be Perkins getting every snap.

If that’s the case, I like the RAMS (+115) to win outright against the Bengals.

Against the spread

Preseason games have been fairly close this year, and the Rams have played 2 games that were decided by 1 possession. The Bengals were beaten handily by the Giants in Week 2, and while I don’t expect another lopsided game in this one, I do think it’ll be the Rams coming out on top.

Getting 2.5 points, I like the RAMS +2.5 (-103) to cover and at least keep the score close – even if the Bengals wind up winning.

[the_huddle]

Over/Under

The total has gone Over in each of the Rams and Bengals’ first 4 games of the preseason. Even without starters playing in this one, I expect both teams to put up enough points to push the total over the 37.5-point line.

Perkins provides a spark for the Rams and Brandon Allen is a capable quarterback in Cincinnati – even if he isn’t overly aggressive.

Bet the OVER (-115).

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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Fantasy football: Where to draft Los Angeles Rams QB Matthew Stafford

Analyzing Los Angeles Rams QB Matthew Stafford’s 2022 fantasy football ADP and where you should target him in your drafts.

About the worst thing a team aspiring to go back-to-back as Super Bowl champs can have is its franchise quarterback with elbow problems before the season starts. That’s the case for the Los Angeles Rams and quarterback Matthew Stafford, who has sat out almost all of training camp with elbow tendinitis.

Below, we look at Matthew Stafford‘s 2022 fantasy football average draft position (ADP) and where you should draft him.

The Rams swung a blockbuster trade prior to last season with the belief that Stafford was all that stood between Los Angeles and a Super Bowl title and they were right. Stafford threw for almost 5,000 yards with 41 touchdowns and consistently posted big fantasy numbers on a week-to-week basis. Yet, his elbow is getting all the attention now.

Matthew Stafford’s ADP: 91.64

(ADP data courtesy of MyFantasyLeague.com; last updated at time of this publishing – ADPs continually change as more drafts occur)

Coming off a season like he had last year, if healthy Stafford would be a top-5 or 6 quarterback. As it stands, his ADP has him as the 13th-ranked quarterback in the abyss of where QBs are going in drafts.

[the_huddle]

In the span of 5 rounds (the 9th to the 13th) only 4 quarterbacks are coming off the board. The drought begins after Aaron Rodgers (Green Bay Packers) at 76.17 and continues until Tua Tagovailoa (Miami Dolphins) at 122.74. In between (almost 50 picks) only 4 quarterbacks are coming off draft boards — Trey Lance (San Francisco 49ers) at 88.11, Stafford at 91.64, Derek Carr (Las Vegas Raiders) at 93.08 and Kirk Cousins (Minnesota Vikings) at 105.92.

Matthew Stafford’s 2021 stats

Games: 17

Passing yards: 4,886

Completions | attempts: 404 | 601

Passing touchdowns: 41

Interceptions: 17

Carries | rushing yards: 32 | 43

Rushing touchdowns: 0

Where should you draft Stafford?

The million-dollar question is how bad is Stafford’s elbow? From this ranking, it’s clear that the fear is that Stafford won’t make it through the season. He’s never going to give you value as a runner — he hasn’t scored a rushing touchdown in the last 5 years — but when you can pile up the passing yards and touchdowns that Stafford does, you don’t need to run.

I would definitely have him in front of Lance and probably Rodgers as well. That would put him at QB11 and he can be paired with another quarterback that can carry the load if he misses times.

It seems like a no-brainer that, unless his elbow is an ongoing issue that becomes obvious, grabbing Stafford as your QB2 is a gamble worth taking. As long as you have someone you like already on the roster, if Stafford plays anywhere close to his 2021 level in his 1st year in L.A., you will be making difficult decisions every week on who to play — and I’d go with the guy who has Cooper Kupp more times than not.

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Fantasy football: Where to draft Arizona Cardinals WR Marquise Brown

Analyzing Arizona Cardinals WR Marquise Brown’s 2022 fantasy football ADP and where you should target him in your drafts.

Things looked like they were heading in the right direction for Arizona Cardinals wide receiver Marquise Brown when he finished off his 3rd season in Baltimore. He had seen a steady increase in targets, receptions and yards every year and was emerging as the go-to wide receiver on the Ravens’ roster.

After initial contract extension talks proved fruitless, Brown was abruptly traded to the Cardinals, where he will be asked to be a major contributor to Kyler Murray and the Arizona offense while star receiver DeAndre Hopkins serves his suspension, as well as after he returns.

Below, we look at Marquise Brown‘s 2022 fantasy football average draft position (ADP) and where you should draft him.

Brown was a PPR dream last year, catching 91 passes as a bargain player in the low-20s for an ADP. He’s coming to an offense that throws a lot more and he remains as a WR29 in ADP rankings and a late-7th round pick in fantasy drafts.

Marquise Brown’s ADP: 67.75

(ADP data courtesy of MyFantasyLeague.com; last updated at time of this publishing – ADPs continually change as more drafts occur)

Given that his forte is running crossing routes to separate from defenders with the occasional bomb mixed in, it’s a little surprising that he is still on the board when a huge wide receiver run takes place in the middle to the end of the 7th round.

Brown is the middle of it, barely behind Chris Godwin (Tampa Bay Buccaneers) at 64.84 and Gabriel Davis (Buffalo Bills) at 66.69 and just ahead of Amari Cooper (Cleveland Browns) at 68.83 and Darnell Mooney (Chicago Bears) at 68.86.

[the_huddle]

Marquise Brown’s 2021 stats

Games: 16

Receptions | targets: 91 | 146

Receiving yards: 1,008

Receiving touchdowns: 6

Where should you draft Brown?

Brown has the ability to make plays and has the speed to do damage, but it wasn’t until last season when he was asked to be a primary target every game. Coming to Arizona plays to his strengths. He will have the ability to be a key component in an offense that wants to throw 40 or more times a game by design and force the issue in the strongest division in the NFL.

Brown seems to be underrated for this ranking, but I think it’s a nice place for someone looking for a WR3 or WR4 with some high upside. When Hopkins comes back, he will likely take on a reduced role, but the time he has with Murray until then will be valuable and, if they’re on the same page, Brown has strong sleeper potential.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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Fantasy football: Where to draft Tampa Bay Buccaneers WR Chris Godwin

Analyzing Tampa Bay Buccaneers WR Chris Godwin’s 2022 fantasy football ADP and where you should target him in your drafts.

Late in December of the 2021 season, Tampa Bay Buccaneers wide receiver Chris Godwin was on his way to blowing past 100 receptions as the leading target and receiver from QB Tom Brady. But that all came to a screeching halt when Godwin suffered a torn ACL and strained MCL that required surgery and abruptly ended his season.

Below, we look at Chris Godwin‘s 2022 fantasy football average draft position (ADP) and where you should draft him.

While reports out of Tampa Bay say that Godwin is making extremely good progress and the organization showed the confidence in him to re-sign him in the offseason without knowing how his recuperation would go, he is said to be targeting his return for Week 1. Where his ADP has him, if he is back anywhere close to 100 percent to start the season, he’s a bargain.

Chris Godwin’s ADP: 64.84

(ADP data courtesy of MyFantasyLeague.com; last updated at time of this publishing – ADPs continually change as more drafts occur)

There have been well-documented runs on positions according to ADP numbers and the 7th round of 10-player drafts sees a slew of wide receivers that have previously gone much higher still being available.

As ADP numbers stand now, Godwin is No. 27 among wide receivers — an incredibly low number for what he and Brady have done together. His ADP comes in the middle of a WR run that has JuJu Smith-Schuster (Kansas City Chiefs) ahead of him at 62.08, followed closely by Gabriel Davis (Buffalo Bills) at 66.69, Marquise Brown (Arizona Cardinals) at 67.75 and Amari Cooper (Cleveland Browns) at 68.63.

[the_huddle]

Chris Godwin’s 2021 stats

Games: 14

Receptions | targets: 98 | 127

Receiving yards: 1,103

Receiving touchdowns: 5

Where should you draft Godwin?

This is a roll of the dice on Godwin’s recuperative powers. His ADP has him as a low-end WR3 and for those who opt to wait on drafting quarterbacks and tight ends, he could be a 4th wide receiver on a fantasy roster, which should make him even more valuable when not required to start every week.

At this portion of the draft, I’m willing to roll the dice on players who may have some question marks. You don’t want too many dinged up players on your roster, but there comes a point when value meets risk.

Godwin finds himself in a “prove it” type of ranking (and in his NFL career on a 1-year deal) and there are some fantasy players that won’t have him rated this high. But there only needs to be 1 in any fantasy league and, if you’ve already got 2 good WRs on your roster, don’t hesitate to pull the trigger barring a setback prior to your draft.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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Fantasy football: Where to draft New Orleans Saints RB Alvin Kamara

Analyzing New Orleans Saints RB Alvin Kamara’s 2022 fantasy football ADP and where you should target him in your drafts.

There are always factors that can impact the fantasy football value of a player — a change in quarterback, a change in offensive coaching staff, an injury history or a potential suspension. In the case of New Orleans Saints running back Alvin Kamara, you can check all those boxes. Kamara is under investigation following a brutal altercation in Las Vegas in the offseason and, depending on how the case progresses, it could impact his 2022 season.

Below, we look at Alvin Kamara‘s 2022 fantasy football average draft position (ADP) and where you should draft him.

In his first year post-Drew Brees, Kamara saw the flip of his first 4 seasons. He set a career high with 240 carries, but had never had fewer than 80 receptions in his first 4 seasons before catching 47 last year in 13 games. He is at his best when he is catching the ball more and running it less, which is something the Saints will have to balance this season.

Alvin Kamara’s ADP: 18.04

(ADP data courtesy of MyFantasyLeague.com; last updated at time of this publishing – ADPs continually change as more drafts occur)

Without the potential suspension hanging over his head, Kamara might be ranked a little higher than his current ADP, which has him as the 10th ranked running back and coming off the draft board late in the 2nd round in 10-player leagues.

Kamara’s ADP finds him narrowly behind Nick Chubb (Cleveland Browns) at 18.02 and narrowly ahead of Saquon Barkley (New York Giants) at 18.66 and Aaron Jones (Green Bay Packers) at 20.50.

[the_huddle]

Alvin Kamara’s 2021 stats

Games: 13

Carries | rushing yards: 240 | 898

Rushing touchdowns: 4

Receptions | receiving yards: 47 | 439

Receiving touchdowns: 5

Where should you draft Kamara?

He may be a draft-day decision depending on when league’s conduct their annual drafts. Trying to get as much information as possible in the days and even hours leading up to your draft could be critical, but, as things stand at the moment, the buzz is that the case is currently moving slowly and could drag out beyond this season, which would leave Kamara fine for 2022.

For those being the last in a 10-player league to select a running back, which is where those fantasy owners would be sitting if the ADP numbers hold up,  Kamara comes with some red flags. Not only is his legal situation a concern, he hasn’t played every game in a season since his rookie year and missed 4 games last year.

While I would be likely to make a point to get a couple of other running backs in the next 3 picks if I was to take Kamara, his dual threat ability makes him one of the most dangerous fantasy players in the league and he is capable of putting up consistently good numbers and enormous totals 3 or 4  times a year.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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Seattle Seahawks at Dallas Cowboys odds, picks and predictions

Analyzing Friday’s Seattle Seahawks at Dallas Cowboys odds and lines, with expert NFL picks, predictions and best bets.

The Seattle Seahawks (0-2) visit the Dallas Cowboys (1-1) in the preseason finale Friday. Kickoff is 8 p.m. ET at AT&T Stadium (NFL Network). Below, we analyze Tipico Sportsbook‘s lines around the Seahawks vs. Cowboys odds, and make our best NFL picks, predictions and bets.

The Seahawks are coming off an offseason in which they traded away QB Russell Wilson. They lost their preseason opener 32-25 to the Pittsburgh Steelers and dropped their 2nd game 27-11 to the Chicago Bears.

The Cowboys lost their preseason opener 17-7 to the Denver Broncos and  followed that up with a 32-18 win over the Los Angeles Chargers. The Cowboys seek to defend their NFC East division title this coming season.

Seahawks at Cowboys odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 4:04 p.m. ET.

  • Money line (ML): Seahawks -320 (bet $320 to win $100) | Cowboys +250 (bet $100 to win $250)
  • Against the spread (ATS): Seahawks -6.5 (-115) | Cowboys +6.5 (-105)
  • Over/Under (O/U): 37.5  (O: -112 | U: -108)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Seahawks at Cowboys picks and predictions

Prediction

Seahawks 24, Cowboys 20

Money line

The Cowboys are going to sit their starters, while the Seahawks have shifted practice reps to their starters. They are expected to get playing time in the preseason finale.

So while the Cowboys will have young players in the lineup and guys who are battling to just make the roster, the Seahawks will have their starters on the field, at least to start things off.

The line reflects that, making a bet on the Seahawks worth very little. PASS on the money line

Against the spread

The focus for this final game, especially once the starters for Seattle come out of the game, will be to stay healthy. Yes, potential back-of-the-roster guys are battling for NFL jobs, but the last part of the game will definitely slow down.

Seattle’s starters are not considered to be among the league’s best, so it will be a matter of how big of a lead they build before things even out.

Expect the score to tighten as the game goes on.

Take the COWBOYS +6.5 (-105).

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Over/Under

The Seahawks have had both preseason games finish with at least 38 points. The Cowboys had their last game hit 50 total points but their opener had only 24.

Take OVER 37.5 (-112).

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If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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Los Angeles Chargers at New Orleans Saints odds, picks and predictions

Analyzing Friday’s Los Angeles Chargers at New Orleans Saints odds and lines, with expert NFL picks, predictions and best bets.

The Los Angeles Chargers (0-2) and New Orleans Saints (0-2) will wrap up their preseason slate on Friday night at the Caesars Superdome in New Orleans. Kickoff will be at 8 p.m. ET. Below, we analyze Tipico Sportsbook‘s lines around the Chargers vs. Saints odds, and make our best NFL picks, predictions and bets.

The Chargers lost 29-22 to the Los Angeles Rams in Week 1 and were blown out in Week 2 by the Cowboys 32-18, allowing 2 special teams touchdowns by KaVontae Turpin. QB Justin Herbert and most of the Chargers starters have not played this preseason, thus leading to Easton Stick and Chase Daniel as the top quarterbacks.

The Saints haven’t been much better this summer, also starting the preseason 0-2. They lost to the Houston Texans and Green Bay Packers, and like the Chargers have not been playing most of their starters as well as being without QB Jameis Winston. It’s unclear if Winston will play against the Chargers, and if he doesn’t, it’ll likely be QB Ian Book leading the offense again.

Chargers at Saints nickname odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 4:03 p.m. ET.

  • Money line (ML): Chargers +133 (bet $100 to win $133) | Saints -165 (bet $165 to win $100)
  • Against the spread (ATS): Chargers +3.5 (-135) | Saints -3.5 (+110)
  • Over/Under (O/U): 36.5 (O: -115 | U: -105)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Chargers at Saints picks and predictions

Prediction

Chargers 20, Saints 18

Money line

It’s been a sloppy preseason for both teams, combining for 8 turnovers through 2 games. The Saints are tied for the league-high with 5 turnovers of their own, which shows they’ve gotten away with the mistakes they’ve made.

Stick and Daniel are decent backup quarterbacks to have and I think they’ll have the offense playing well on Friday night. Take the CHARGERS (+133) to win outright.

Against the spread

If you want to protect your ML bet a little bit, you can do so by taking the Chargers to cover the 3.5-point spread. Obviously, the return on that bet is far less than an outright ML wager, but at least if the Chargers wind up losing by 3 points or less, you can still get back some money.

Neither the Saints nor the Texans have covered the spread yet this season, but I like the CHARGERS +3.5 (-135).

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Over/Under

The total went over pretty easily in the Chargers’ first 2 games, combining for 51 and 50 points in those contests. Saints games have been lower-scoring so far, totaling 30 points in each of their first 2 preseason games.

The Chargers defense hasn’t looked great so I expect the Saints to score more than the 13 and 10 points they put up the last 2 weeks, and L.A.’s offense has shown some signs of life so far. Bet the OVER 36.5 (-115).

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Buffalo Bills at Carolina Panthers odds, picks and prediction

Analyzing Friday’s Buffalo Bills at Carolina Panthers odds and lines, with expert NFL picks, predictions and best bets.

The Buffalo Bills (2-0) and Carolina Panthers (1-1) wrap up their preseason schedule Friday. Kickoff from Bank of America Stadium is scheduled for 7 p.m. ET. Below, we analyze Tipico Sportsbook‘s lines around the Bills vs. Panthers odds, and make our best NFL picks, predictions and bets.

The Bills throttled the visiting Denver Broncos 42-15 last weekend, playing the starters for most of the 1st quarter. But the run game continued to be impressive well after the 1st unit was out of there, showing some tremendous organizational depth.

Coach Sean McDermott confirmed early this week that most of his 1st-team players will not play Friday in Charlotte, including star QB Josh Allen.

The Panthers were on the short end of a 20-10 loss at New England after joint practices with the Patriots last week. The only touchdown came via pick-6 from DB Tae Hayes, too.

Carolina made headlines this week, officially naming QB Baker Mayfield as the starter, while also announcing rookie QB Matt Corral (foot) suffered a long-term injury. Mayfield is expected to play into the 2nd quarter Friday, with QBs Sam Darnold and PJ Walker finishing up.

Bills at Panthers odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 4:01 p.m. ET.

  • Money line (ML): Bills +220 (bet $100 to win $220) | Panthers -280 (bet $280 to win $100)
  • Against the spread (ATS): Bills +6.5 (-115) | Panthers -6.5 (-105)
  • Over/Under (O/U): 39.5 (O: -117 | U: -103)

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Bills at Panthers picks and predictions

Prediction

Panthers 22, Bills 16

Money line

The Panthers (-280) will use the 1st-team offense well into the 2nd quarter, while the Bills (+220) will take a low-key approach to this preseason finale, using mostly reserves.

The advantage is to the home side, but you can’t risk nearly 3 times your potential return on a favorite in a preseason game.

AVOID.

Against the spread

The PANTHERS -6.5 (-105) are worth playing lightly, as the starters on offense should feature well into the 2nd quarter in front of the home fans. Coach Matt Rhule will give us a glimpse of what to expect from the Panthers, and it might be a little better than the regular season, since they’ll be facing a Bills team using mostly reserves.

[the_huddle]

Over/Under

The UNDER 39.5 (-103) is the way to go here, as no Allen means the offense is likely to be a little slower for Buffalo. Of course, that wasn’t the case at home against Denver last week even after Allen exited.

Still, the Panthers offense managed just a field goal last weekend, and it is still a work in progress.

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If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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Bet Slippin’ podcast: 2022 AFC North gambling preview

Nathan Beighle invites back OutKick handicapper Geoff Clark to continue the Bet Slippin’s 2022 NFL preview series discussing the AFC North.

SportsbookWire.com handicapper Nathan Beighle connects with OutKick sports betting analyst Geoff Clark to preview the AFC North, including breakdowns of the Cincinnati Bengals, Pittsburgh Steelers, Cleveland Browns and Baltimore Ravens.

Listen as they offer up their picks, predictions and best bets. Visit SportsbookWire.com for more sports betting analysis.

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list.

(If the podcast player does not display, please click here.)

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Bet Slippin’ podcast rundown

Cincinnati Bengals | Time – 2:37

Pittsburgh Steelers | Time – 17:58

Cleveland Browns | Time – 31:01

Baltimore Ravens | Time – 39:48

Goin’ to the window (best bets) | Time – 45:31

More AFC North coverage:

Like, subscribe, rate and review SportsbookWire’s sports betting podcast on your favorite podcasting platform: Google PodcastsSpotify | Apple Podcasts.

Want some action on the 2022 NFL season or any other sport? Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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