Arizona Cardinals at Tennessee Titans odds, picks and predictions

Analyzing Saturday’s Arizona Cardinals at Tennessee Titans odds and lines, with expert NFL picks, predictions and best bets.

The Arizona Cardinals (1-1) and Tennessee Titans (1-1), after holding a joint practice with each other on Wednesday, close out the preseason with Saturday’s kickoff set for 7 p.m. ET at Nisson Stadium in Nashville. Below, we analyze Tipico Sportsbook‘s lines around the Cardinals vs. Titans odds, and make our best NFL picks, predictions and bets.

The Cardinals beat the Cincinnati Bengas 36-23 in their preseason opener,  and followed that up with a 24-17 loss to the Baltimore Ravens. They have not played their starters yet in the preseason and will not play their starters in the finale against the Titans. QB Trace McSorley will start for the Cardinals and play into the 2nd half, while undrafted rookie QB Jarrett Guarantano will close things out.

The Titans are also expected to keep their starters out of the game, giving rookie QB Malik Willis the opportunity to get game reps. After a 23-10 loss to the Ravens in their preseason opener, they beat the Tampa Bay Buccaneers 13-3 last week.

Cardinals at Titans odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 3:22 p.m. ET.

  • Money line (ML): Cardinals +133 (bet $100 to win $133) | Titans -165 (bet $165 to win $100)
  • Against the spread (ATS): Cardinals +3.5 (-135) | Titans -3.5 (+110)
  • Over/Under (O/U): 35.5 (O: -110 | U: -110)

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Cardinals at Titans picks and predictions

Prediction

Cardinals 24, Titans 17

Money line

Both teams are 1-1 this preseason and have not been playing their starters. The absence of starters creates highly variant potential outcomes.

If one team were playing its starters in this game, the pick would be easier, but without that, the best bet on a preseason game is to go with the best value, as backups and players battling to have an NFL job against each other is really a tossup. Take the CARDINALS (+133).

Against the spread

PASS on the spread. This is only because it is a preseason game. Both teams are 1-1 ATS in the preseason.

The Cardinals blew out the Titans in the regular season last year 38-13 in Week 1 and have won their only other preseason road game.

However, again, preseason games that don’t involve starters are tossups. You go with the best value. That is the money line in this case.

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Over/Under

The Cardinals’ 2 preseason games have had totals of 41 and 59 points. The Titans’ highest total was 33 points.

Arizona’s defense has allowed both preseason opponents to reach the 20s. The Titans haven’t scored more than 13 points in a game this preseason.

Are the Titans going to struggle to score again or will they be able to put points on the board as both of Arizona’s opponents have done?

I LEAN OVER 35.5 (-110).

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