The Arizona Wildcats will kick off their season Saturday against the USC Trojans (1-0). Kickoff is Saturday at 3:30 p.m. ET at Arizona Stadium in Tucson. Below, we analyze the USC-Arizona college football betting odds and lines, with picks and predictions.
USC is 20th in the Amway Coaches Poll.
USC at Arizona: Betting odds, spread and lines
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 9:25 a.m. ET.
- Money line: USC -556 (bet $556 to win $100) | Arizona +400 (bet $100 to win $400)
- Against the spread/ATS: USC -14 (-121) | Arizona +14 (+100)
- Over/Under: 67.5 (O: -110 | U: -110)
USC at Arizona: Three things to know
- USC erased a 13-point deficit against Arizona State in the final five minutes of the game to win 28-27, despite four turnovers.
- Arizona was scheduled to open the season last week against Utah, but the game was canceled due to COVID-19 concerns.
- USC QB Kedon Slovis had 381 passing yards, two touchdowns and an interception against Arizona State.
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USC at Arizona: Odds, betting lines, predictions and picks
Prediction
USC 41, Arizona 20
Money line (ML)
USC has offense. Arizona’s defense is developing, but the Wildcats are still building their team. They are not at all on the same level as the Trojans. Slovis will have no problem picking apart the secondary. There isn’t much money in it, so betting the money line won’t win you much, but it is a sure thing. If you want to bet the money line, take USC (-556), but you are better off betting the spread.
Against the spread (ATS)
USC narrowly got the win over Arizona State but failed to cover the spread. The Trojans have the advantage of being the better team and having played a game, while Arizona has not yet been able to get those first live snaps under its belt. This will be a blowout. Take USC -14 (-121).
Over/Under (O/U)
USC won’t have any problem scoring points, but it will keep Arizona from scoring enough to go Over the projected total. Take UNDER 67.5 (-110).
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