Toronto Blue Jays at San Diego Padres odds, picks and predictions

Analyzing Friday’s Toronto Blue Jays at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Toronto Blue Jays (10-9) and San Diego Padres (11-10) open a 3-game series at Petco Park Friday. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Blue Jays vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 2-1 last season

The Padres are returning home after 2 straight road series. They went 4-2 in those games, losing their last outing 1-0 to the Milwaukee Brewers Wednesday. San Diego is 5-5 straight up at home and 11-10 on the run line this season.

The Blue Jays had their 4-game winning streak snapped in a 6-4 series-finale loss to the New York Yankees Wednesday. They have won 4 of their last 5 and 6 of their last 9. Toronto is 10-9 on the run line this season.

Blue Jays at Padres projected starters

RHP Yariel Rodriguez vs. RHP Matt Waldron

Rodriguez (0-0, 2.45 ERA) makes his 2nd start. The rookie allowed 1 ER on 4 H and 2 BB with 6 K in 3 2/3 IP in his debut, a 5-3 home win, vs. the Colorado Rockies Saturday.

  • 2024 with Buffalo (AAA): Allowed 1 H and 3 BB with 10 K across 6 1/3 scoreless innings in 2 starts
  • Previously played with the Chunichi Dragons in Japan’s Central League

Waldron (0-1, 3.14 ERA) makes his 4th start. He has a 1.64 WHIP, 3.8 BB/9 and 10.0 K/9 in 14 1/3 innings.

  • Last start: No-decision, 5 IP, 1 ER, 3 H, 4 BB, 4 K in 5-2 road loss to Los Angeles Dodgers Saturday
  • Padres are 0-3 in his starts; they were 3-5 in his 8 appearances last season

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Blue Jays at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:25 a.m. ET.

  • Moneyline (ML): Blue Jays -102 (bet $102 to win $100) | Padres -116 (bet $116 to win $100)
  • Run line (RL)/Against the spread (ATS): Blue Jays -1.5 (+160) | Padres +1.5 (-194)
  • Over/Under (O/U): 8.5 (O: -104 | U: -118)

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Blue Jays at Padres picks and predictions

Prediction

Padres 6, Blue Jays 3

Moneyline

BET PADRES (-116).

San Diego has been playing well as of late, and its offense has been hot. The Padres have tallied 6 or more runs in 3 of their last 4 games, all of which came against either the Brewers or Dodgers. Milwaukee and Los Angeles each sit atop their respective divisions, and the Padres went 4-2 in back-to-back series against them from April 12-17.

While the Blue Jays have won consistently over their last 5, they haven’t scored more than 5 runs in a game since April 6, so keeping up with the efficient Padres offense could be difficult. Toronto is just 3-6 on the road as well.

Back PADRES (-116).

Run line/Against the spread

PASS.

There’s not great value here, as the Padres are too expensive as run-line underdogs and the Blue Jays don’t have playable odds as run-line favorites.

Over/Under

LEAN OVER 8.5 (-104).

The Blue Jays are 9-9 O/U on the season and have gone Over in 2 straight games. They have scored at least 4 runs in back-to-back games and tallied exactly 5 in 3 of their last 5.

San Diego has gone Over in 3 of its last 4 and in 5 of its last 7. It is 11-9-1 O/U on the season. The Padres have tallied at least 6 runs in 5 of their last 7 as well, so their offense has been consistently producing as of late.

Back OVER 8.5 (-104).

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