Big 12 week 1 predictions: West Virginia with a tough road matchup vs. Penn State

West Virginia goes on the road in week one to take on the Penn State Nittany Lions in a pivotal nonconference matchup. Here are this week’s Big 12 picks.

There aren’t a lot of big-time matchups in the Big 12 in week one, but there are a few intriguing contests. West Virginia goes on the road to take on Penn State. Texas Tech is the only other Big 12 team playing away from home this week, but take on Wyoming in what could be an interesting contest.

Houston hosts UTSA, a team that’s started to gain national recognition among Group of Five teams.

UCF got the Big 12 started off right with a huge win over Kent State on Thursday night. John Rhys Plumlee had 371 combined passing and rushing yards and four total touchdowns in their 56-6 win over Kent State.

Can the conference keep things going starting Friday night with Kansas hosting Missouri State?

There will be some big-time performances this week. Here are our Big 12 predictions for week one.

College Football Expert Picks, Predictions: Week 1 Saturday

Week 1 college football expert picks and predictions for Saturday including Oregon vs Georgia, Utah at Florida, and Notre Dame at Ohio State

College football expert picks, predictions for Week 1, highlighted by Oregon vs Georgia, Utah at Florida, and Notre Dame at Ohio State


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* next to the pick means the team will win, but not cover.
Click on each game for the game preview and CFN Prediction

Week 1 College Football Expert Picks
Colorado St at Mich | Cincinnati at Ark
Oregon at Georgia | Arizona at SDSU
UTEP at Oklahoma | Utah at Florida
Memphis at Miss St | UNC at App State
BYU at USF | Rice at USC
Utah St at BamaGa St at So Carolina
Notre Dame at Ohio StULM at Texas
Louisville at SyracuseBoise St at Oregon St
Kent St at WashingtonWKU at Hawaii
Florida St at LSUClemson at Ga Tech
Expert Pics Week 0 | Week 1 Thurs/Friday
CFN Predictions & Game Previews
2022 CFN Preview of all 131 Teams

Colorado State at Michigan

Line: Michigan -21, o/u: 57.5

Eric Bolin, RazorbacksWire.com: Michigan
Evan Bredeson, CornhuskersWire.com: Michigan
Tony Cosolo, ColoradoBuffaloesWire.com: Michigan
Jeff Feyerer, CFN: Michigan*
Pete Fiutak, CFN: Michigan
Dan Harralson, VolsWire.com: Michigan*
Phil Harrison, BuckeyesWire.com: Michigan
Jeremy Mauss, MWwire.com Michigan*
Big Game Ben Niewoehner, CFN Michigan
Ethan Niewoehner, CFN Michigan
Tyler Nettuno, LSUTigerswire.com Michigan
Zack Pearson, TarHeelswire.com Michigan
Johnny Rosenstein, SportsBookWire.com: Michigan
Nick Shepkowski, FightingIrishWire.com: Michigan
AJ Spurr, RollTidewire.com Michigan
Scott Steehn, WinnersandWhiners.com: Michigan*
Joe Vitale, UGAWire.com: Michigan
John Williams, SoonersWire.com: Michigan
Clucko the Chicken (a coin flip), CFN: Colorado State
CONSENSUS PICK: Michigan

Week 1 College Football Expert Picks
Colorado St at Mich | Cincinnati at Ark
Oregon at Georgia | Arizona at SDSU
UTEP at Oklahoma | Utah at Florida
Memphis at Miss St | UNC at App State
BYU at USF | Rice at USC
Utah St at BamaGa St at So Carolina
Notre Dame at Ohio StULM at Texas
Louisville at SyracuseBoise St at Oregon St
Kent St at WashingtonWKU at Hawaii
Florida St at LSUClemson at Ga Tech
Expert Pics Week 0 | Week 1 Thurs/Friday

NEXT: Cincinnati at Arkansas Expert Picks, Predictions

College Football Expert Picks, Predictions: Week 1 Thursday, Friday

Week 1 college football expert picks and predictions for Thursday and Friday including West Virginia at Pitt, Penn State at Purdue, and Illinois at Indiana

College football expert picks, predictions for Week 1, highlighted by West Virginia at Pitt, Penn State at Purdue, and Illinois at Indiana


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* next to the pick means the team will win, but not cover.
Click on each game for the game preview and CFN Prediction

Week 1 College Football Expert Picks
Ball St at Tennessee | WVU at Pitt
CMU at Ok State | La Tech at Missouri
Penn St at Purdue | NMSU at Minnesota
WMU at Mich St | Va Tech at ODU
Temple at Duke | Illinois at Indiana
TCU at ColoradoWeek 1 T/F Schedule Picks
CFN Predictions & Game Previews
2022 CFN Preview of all 131 Teams

Ball State at Tennessee

Line: Tennessee -32.5, o/u: 67.5

Eric Bolin, RazorbacksWire.com: Tennessee
Evan Bredeson, CornhuskersWire.com: Tennessee
Patrick Conn, College Wires Editor: Tennessee
Tony Cosolo, ColoradoBuffaloesWire.com: Tennessee*
Jeff Feyerer, CFN: Tennessee*
Pete Fiutak, CFN: Tennessee*
Dan Harralson, VolsWire.com: Tennessee
Phil Harrison, BuckeyesWire.com: Tennessee
Joey Ickes, AggiesWire.com: Tennessee
Jeremy Mauss, MWwire.com Tennessee*
Kevin McGuire, NittanyLionsWire.com: Tennessee
Big Game Ben Niewoehner, CFN Tennessee*
Ethan Niewoehner, CFN Tennessee*
Zack Pearson, TarHeelswire.com Tennessee
Johnny Rosenstein, SportsBookWire.com: Tennessee
Nick Shepkowski, FightingIrishWire.com: Tennessee*
AJ Spurr, RollTidewire.com Tennessee
Scott Steehn, WinnersandWhiners.com: Tennessee*
Joe Vitale, UGAWire.com: Tennessee*
John Williams, SoonersWire.com: Tennessee
Clucko the Chicken (a coin flip), CFN: Ball State
CONSENSUS PICK: Tennessee*

NEXT: West Virginia at Pitt Expert Picks, Predictions

College Football Predictions, Schedule, Game Previews, Lines, TV: Week 1 Friday

College football predictions, schedule, game previews, lines and TV listings for the Friday Week 1 games.

College football predictions, schedule, game previews, lines and TV listings for the Friday Week 1 games.


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North Carolina at Virginia Tech

6:00, ESPN
Line: North Carolina -5.5, o/u: 64

Duke at Charlotte

7:00, CBS Sports Network
Line: Duke -6.5, o/u: 60.5

CFN Week 1 Experts Picks: College

Old Dominion at Wake Forest

7:00, ACC Network
Line: Wake Forest -32, o/u: 62

St. Francis (PA) at Eastern Michigan

7:00, ESPN3
Line: Eastern Michigan -32.5, o/u: 54.5

5 Best Predictions ATS: Week 1 Thursday

South Dakota at Kansas

8:00, Big 12/ESPN+
Line: Kansas -13, o/u: 56

Michigan State at Northwestern

9:00, ESPN
Line: Northwestern -3, o/u: 46

Week 1 Schedule, Predictions For Every Game

Northern Colorado at Colorado

9:00, Pac-12 Network
Line: No Line, o/u: No Line

South Dakota State at Colorado State

9:00, FS1
Line: Colorado State -3, o/u: 52.5

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CFN Fearless Predictions & Game Previews

College Football Predictions, Schedule, Game Previews, Lines, TV: Week 1 Thursday

College football predictions, schedule, game previews, lines and TV listings for the Thursday Week 1 games.

College football predictions, schedule, game previews, lines and TV listings for the Thursday Week 1 games.


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Temple at Rutgers

6:30, Big Ten Network
Line: Rutgers -14.5, o/u: 52

CFN Week 1 Experts Picks: College

Boise State at UCF

7:00, ESPN
Line: UCF -5.5, o/u: 68

Long Island University at FIU

7:00, ESPN3
Line: FIU -7, o/u: 60.5

Wagner at Buffalo

7:00, ESPN3
Line: Buffalo -43.5, o/u: 56

Western Illinois at Ball State

7:00, ESPN+
Line: Ball State -29.5, o/u: 58.5

The Citadel at Coastal Carolina

7:00, ESPN+
Line: Coastal Carolina -35, o/u: 56.5

Houston Baptist at New Mexico

7:00, Mountain West Network
Line: New Mexico -24.5, o/u: 66

East Carolina vs. Appalachian State

7:30, ESPNU
Line: Appalachian State -10, o/u: 56

USF at NC State

7:30, ACC Network
Line: NC State -17.5, o/u: 60.5

UC Davis at Tulsa

7:30, ESPN+
Line: Tulsa -25.5, o/u: 55

Weber State at Utah

7:30, Pac-12 Network
Line: Utah -30.5, o/u: 49

5 Best Predictions ATS: Week 1 Thursday

Bowling Green at Tennessee

8:00, SEC Network
Line: Tennessee -35, o/u: 60.5

Ohio State at Minnesota

8:00, FOX
Line: Ohio State -14, o/u: 62.5

UT Martin at WKU

8:00, ESPN+
No Line, o/u: No Line

CFN Week 1 Experts Picks: NFL

Eastern Washington at UNLV

10:00, Stadium
Line: UCLA -17.5, o/u: 68.5

Southern Utah at Arizona State

10:30, Pac-12 Network
Line: Arizona State -47, o/u: 59

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CFN Fearless Predictions & Game Previews