10 Best College Football Predictions Against The Spread: Week 6

What college football games appear to be the best bets and the best picks against the spread going into Week 6?

What college football games appear to be the best bets and the best picks against the spread going into Week 6?


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Week 6 Fearless Predictions, Game Previews 
CFN Week 6 Experts Picks: College
CFN Week 5 Experts Picks: NFL 
Week 6 Schedule, Game Times, Game Previews
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I apologize for really and truly thinking Vanderbilt was going to act like the SEC program it is against UConn. Instead of it being a layup of a Commodore blowout, it took a late rally to survive 30-28 and not covering the 14.5

I failed you, America.

I promised you something special after going 4-6 in Week 4, and going 9-1 ATS isn’t good enough.

(Or, to move the dial off the snooty-brag setting, if you’ve followed me over the years you know this means the time for the HARD fade is soon to come.)

Pushing that boulder up the mountain again …

Results So Far ATS: 39-21-1

Click on each game for the preview

10. Arkansas at Ole Miss

LINE Point Total 66.5
ATS PICK Under

And it’ll probably get up to closer to 68 by gametime.

First, 66.5 is hard to get to, even for these two teams. Last year these two got the respective Os going and it still landed on 54.

Second, if you believe Arkansas is going to pull this off, it’ll probably do it controlling the game and tempo throughout.

No Hog game this year – even with 40 put up against Texas and 45 against Georgia Southern – got to 67. Three of the four Ole Miss games got past the mark, but the one that didn’t was against Alabama when the Rebels couldn’t stop the run.

Think of it this way. Georgia couldn’t have been better last week and it only got 37 on the Hogs.

Week 5 NFL Expert Picks

9. Maryland at Ohio State

LINE Point Total 71
ATS PICK Under

The hard and fast rule is to never, ever take the over when the world is asking for 80, and that worked out just fine with the under on Ole Miss and Alabama last week – they got to 63.

But what about 72? Ehhhhhh, not close enough, but worth a shot here on the biggest point total of the day.

Maryland-Ohio State opened at 72.5 and dipped down a bit. No one likes to take the under on a major game that everyone will watch, but getting past 71 is a large ask.

If the game gets there, then blow off the loss, sit back, and enjoy the show.

Maryland might be improved, but it only hung up a big number on Howard. It’s not getting 62 on Ohio State, and the second-best scoring output was 67.

Yeah, some might have visions of the wild 52-51 Buckeye win in 2018, and the 31 allowed to Minnesota and 35 to Oregon is enough to worry. This will get into the 60s, but 72 is a push even for these two.

Week 6 Schedule, Predictions For Every Game

8. Florida State at North Carolina

LINE North Carolina -17.5
ATS PICK North Carolina

Florida State was able to close out last year with a win over Duke, and it beat Jacksonville State along the way. The stunner for that awful, awful team was a 31-28 win over a North Carolina squad that did just about everything offensively but score more points than the other team.

That won’t be an issue this week.

The Tar Heels have been way flaky – hello, Georgia Tech 45, UNC 22 – but that wasn’t in Chapel Hill, and neither was the Virginia Tech game. They annihilated Georgia State, Virginia, and Duke, and now it’s a revenge game with FSU coning in.

Sam Howell will throw for over 300 yards getting off the bus.

Revenge Game Part 2 …

NEXT: College Football Pick Against The Spread No. 7: Michigan State at Rutgers

Pac-12 Predictions, Schedule, Game Previews, Lines, TV: Week 6

Pac-12 college football predictions, schedule, game previews, lines, how to watch, and TV listings for Week 6 of the season.

Pac-12 college football predictions, schedule, game previews, lines, how to watch, and TV listings for Week 6 of the season.


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Click on each game for game preview & prediction

Pac-12 Results So Far
SU: 31-15, ATS: 24-19-1, Point Total: 26-18

Friday, October 8

Stanford at Arizona State

10:30, ESPN
Line: Arizona State -13, o/u: 52

Saturday, October 9

Oregon State at Washington State

4:00, Pac-12 Network
Line: Oregon State -4, o/u: 59

Utah at USC

8:00, FOX
Line: USC -3, o/u: 52.5

UCLA at Arizona

10:30, ESPN
Line: UCLA -16, o/u: 61

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Fearless Predictions of Every Game
Bowl Projections | Rankings

UCLA vs Arizona Prediction, Game Preview

UCLA vs Arizona prediction, game preview, how to watch: Saturday, October 9

UCLA vs Arizona prediction, game preview, how to watch: Saturday, October 9


UCLA vs Arizona How To Watch

Date: Saturday, October 9
Game Time: 10:30 ET
Venue: Arizona Stadium, Tucson, AZ
How To Watch: ESPN
Record: UCLA (3-2), Arizona (0-4)
Sign up and live stream college football on ESPN+

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All of the CFN Fearless Predictions

UCLA vs Arizona Game Preview


Why UCLA Will Win

Arizona doesn’t have enough of an offense to keep up.

It played well for a while in the misleading 41-19 loss to Oregon – coming up with over 200 yards rushing and 200 passing – but late turnovers made it ugly.

Overall, though, the running game hasn’t been able to get going, third down conversions are rare, and there’s not enough help from the other side to make a difference.

Basically, Arizona’s lines aren’t good enough yet.

There isn’t nearly enough of a pass rush to get to Dorian Thompson-Robinson and the Bruins downfield passing game that should be able to come up with yards in chunks.

In a perfect world, though, the Bruins take advantage up front and start pounding away from the first drive.

However …

Week 6 CFN College Football Expert Picks

Why Arizona Will Win

UCLA is 3-0 on the year when it runs for over 200 yards, and it’s 0-2 when it doesn’t. Arizona allowed 254 yards on the ground to San Diego State,  and no one else – not BYU, not Oregon – has been able to get past the 200-yard mark.

The top guys aren’t in place quite yet for new Arizona head coach Jedd Fisch, but he made a major statement from the start that his program would play defense, and it’s happening.

The overall numbers aren’t amazing, but considering Arizona went on an impressive run of allowing over 400 yards in 18 of 19 games before the 2021 season – and 22 of 25 going back through 2018 – only allowing one 400-yard day in the first four games is a big step forward.

And now the Wildcat defense has had two weeks off to rest up.

Week 6 College Football Schedule, Predictions, Game Previews

What’s Going To Happen

UCLA will pick it back up again after failing to keep up in the second half against Arizona State.

It’s just the second away game so far – beating Stanford in the first one – with a balanced attack ready to be enough to overcome a strong first quarter start by Arizona.

The Cats won’t be able to keep up.

Week 5 CFN NFL Expert Picks

UCLA vs Arizona Prediction, Line

UCLA 37, Arizona 20
Line: UCLA -16, o/u: 61
ATS Confidence out of 5: 3.5

Must See Rating: 2

5: When Facebook and Instagram are down
1: The Bradshaw Bunch

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Fearless Predictions of Every Game
Bowl Projections | Rankings

College Football Expert Picks, Predictions: Week 6

College football expert picks, predictions for Week 6, highlighted by Oklahoma vs Texas, Penn State at Iowa, and Alabama at Texas A&M.

College football expert picks, predictions for Week 6, highlighted by Oklahoma vs Texas, Penn State at Iowa, and Alabama at Texas A&M.


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* next to the pick means the team will win, but not cover.
Click on each game for the game preview and CFN Prediction

Week 6 Fearless Predictions, Game Previews 
CFN Fearless Predictions & Game Previews

Week 6 Expert Picks
Houston at Tulane | Coastal Car at Ark St
Temple at Cincinnati | Charlotte at FIU
Stanford at Arizona St | Arkansas at Ole Miss
Michigan St at Rutgers | Maryland at Ohio St
Oklahoma vs Texas | South Carolina at Tenn
Vanderbilt at Florida | Boise State at BYU
Georgia at Auburn | Wisconsin at Illinois
Penn State at Iowa | LSU at Kentucky
Michigan at Nebraska | Notre Dame at VT
Alabama at Texas A&M | Utah at USC
UCLA at Arizona | Results So Far 

Houston at Tulane

7:30, ESPN
Line: Houston -6, o/u: 60

Gill Alexander, VSIN: Tulane
Eric Bolin, RazorbacksWire.com: Houston
Patrick Conn, LSUTigersWire.com Tulane
Adam Dubbin, GatorsWire.com Houston
Jeff Feyerer, CFN: Houston
Dan Harralson, VolsWire.com: Houston*
Phil Harrison, BuckeyesWire.com: Houston
Jeremy Mauss, MWwire.com: Houston
Kevin McGuire, NittanyLionsWire.com: Houston*
Big Game Ben Niewoehner, CFN Houston
Johnny Rosenstein, SportsBookWire.com: Houston
Nick Shepkowski, FightingIrishWire.com: Tulane
John Williams, SoonersWire.com: Tulane
Clucko the Chicken, CFN: Tulane
CONSENSUS PICK: Houston*

Week 6 Expert Picks
Houston at Tulane | Coastal Car at Ark St
Temple at Cincinnati | Charlotte at FIU
Stanford at Arizona St | Arkansas at Ole Miss
Michigan St at Rutgers | Maryland at Ohio St
Oklahoma vs Texas | South Carolina at Tenn
Vanderbilt at Florida | Boise State at BYU
Georgia at Auburn | Wisconsin at Illinois
Penn State at Iowa | LSU at Kentucky
Michigan at Nebraska | Notre Dame at VT
Alabama at Texas A&M | Utah at USC
UCLA at Arizona | Results So Far 

NEXT: Coastal Carolina at Arkansas State Expert Picks, Predictions