10 Best College Football Predictions Against The Spread Week 2

10 best predictions for the second full weekend of the college football season. Best bets and picks for Week 2’s Saturday games.

10 best predictions for the second full Saturday of college football. What games appear to be the best bets and best picks for Week 2’s games?


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Week 2 should be gettable.

We’re all supposed to be smart about this, and we’re all supposed to know what we’re doing, but how can you not overreact to how the teams looked in Week 1?

There are always corrections, changed ideas, and crazy thoughts both ways, but it takes about a month to get a real read on just how good all of these teams are.

So beware. All of the picks try to take out the eye-test – at least a little bit – and stick with logic, reason, and …

Whatever. Week 2 is where we go for it, and then clean up the mess in Week 3. It all starts, though, with a long held belief that won’t be broken now …

Results So Far: 15-5-1

Click on each game for the preview

10. Hawaii at Michigan

LINE Michigan -52
ATS PICK Hawaii

If you’ve been reading this piece over the years, you know that you’re supposed to be consistent. Over time, if you stay with it, you’ll be up as long as you don’t stray from the plan.  However …

I actually like Michigan as the pick, but a man is nothing without his principles.

As the schtick goes, if someone is giving you 50 points or more walking into the stadium, you thank them, you don’t ask questions, and you take grab the gift.

Too many things can go wrong. The favorite can pull all the starters early, the underdog can come up with a few late points, the home team bus could get lost – it’s really, really hard to win by more than 50.

The problem is that Hawaii is totally gutted. It can’t hang with the Wolverines in any way, and it’s going to get annihilated.  Michigan might be up 40 at halftime and just stop.

In any event, I’m beating Michigan 52-0 as we speak. Yay.

Unfortunately, though, we have two weeks of Hawaii football to have seen the problem with that, just like …

9. Georgia Southern at Nebraska

LINE Nebraska -23.5
ATS PICK Georgia Southern

I’m staying on the Nebraska Isn’t That Good At College Football train until it stops.

Northwestern with the points against the Huskers was a layup, and there were way too many sputters and coughs last week in the 38-17 win over North Dakota.

Georgia Southern and new head coach Clay Helton got in an easy tune-up against Morgan State, and so until proven otherwise by the Big Red – even though I actually think Scott Frost really will get this thing moving as the season goes on – give me the 23.5 points.

Speaking of sticking with something a tad too long …

8. Kansas at West Virginia

LINE West Virginia -13.5
ATS PICK West Virginia

I’m diving back in one more time to see if the magic happens again.

Kansas was an investment god over stretches in 2020 and 2021 – it never, ever, ever covered with any regularity.

Lance Leipold is a fantastic head coach, he has the program going in the right direction, and Kansas is better than it has been in a long, long time. Asking for a two touchdown win by West Virginia at home, though, isn’t a lot.

I’m buying into the Mountaineer defensive pressure, I’m buying into JT Daniels, and I’m buying into the possibility that Kansas goes back to being that.

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7. Syracuse at UConn

LINE Syracuse -23.5
ATS PICK Syracuse

I can’t believe I’m falling for Syracuse again.

I thought there was something there after a dominant performance at Ohio to start last year, and the next week came a 17-7 home clunker of a loss to Rutgers.

I bought in after an easy win over Georgia Tech in 2020, and then it collapsed in a 14-point home loss to a miserable Duke team.

I loved too much after the 2019 opener against Liberty, and then Maryland went 63-20 on the Orange.

I can’t quit this team.

I’m in that the 31-7 domination of Louisville was for real, I’m not sold that UConn hasn’t improved that much this quickly under Jim Mora Jr., and I’m buying that the Orange really are that good on the lines now.

Be careful if you go with this pick – picks from the heart end up hurting – and be extra wary of …

6. Southern Utah at Utah

LINE Utah -45.5
ATS PICK Southern Utah

I DESPISE FBS vs FCS games after Week 1.

They’re money grabs for the FCS, FBS fans don’t want to see them, and I fully believe that if you’re paying a team to come into your house so you can beat the holy hell out of them – you’re funding most of their athletic department budget – then go ahead and do it.

However, that’s not how coaches think. They want to secure the win, keep everyone healthy, work on some things, and then move on.

I DESPISE picking FBS vs FCS games – too many unknowables and variables – because the FBS teams could almost always win by a gajillion if they wanted.

Utah could beat Southern Utah by 90 if it chose to. However – one 70-7 win over 2013 Weber State aside – Kyle Whittingham usually keeps these games from getting crazy. His Utes haven’t scored more than 40 against an FCS team since taking out Idaho State 56-14 in 2014, and even then the number was 42.

Figure this is something like 41-0, but again, too many weird parts to FBS vs FCS games, so don’t go crazy here.

NEXT: College Football Pick Against the Spread No. 5: Iowa State vs Iowa point total

Syracuse vs UConn Prediction, Game Preview

Syracuse vs UConn game preview, prediction, and breakdown for the Week 2 game on Saturday, September 10

Syracuse vs UConn prediction, game preview, how to watch. Week 2, Saturday, September 10


Syracuse vs UConn How To Watch

Date: Saturday, September 10
Game Time: 7:00 ET
Venue: Pratt & Whitney Stadium, East Hartford, CT
How To Watch: CBS Sports Network
Record: Syracuse (1-0), UConn (1-1)
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Syracuse vs UConn Game Preview

Why Syracuse Will Win

Well that worked.

Syracuse changed up the offense a bit, went to more of a balanced attack, and the defense came up with a terrific performance in the somewhat stunning 31-7 win over Louisville.

RB Sean Tucker is a given – he ran 21 times for 100 yards and a score – but it was QB Garrett Shader who took his game up a few notches with a brilliant 18-of-25 passing day for 236 yards and two scores, and with 94 rushing yards and a touchdown.

And UConn won’t be able to stop any of it.

The Huskies came up with a nice win over Central Connecticut last week, and it wasn’t awful in the loss to Utah State. But the defensive front is going to have a tough time, and the offense can’t turn the ball over three times like it did against the Blue Devils. But …

CFN Expert Picks, Week 2

Why UConn Will Win

Syracuse wasn’t perfect in the opener.

It didn’t turn the ball over, but the 18 penalties kept the game from being easier than it turned out to be.

And yes, UConn is playing better. There’s a stronger ground game with Nathan Carter running well over the first two games. The team overall has been sharper under new head coach Jim Mora Jr., and the defense really is playing well enough to not get steamrolled.

Syracuse was able to pull away from Louisville partly because it was +3 in turnover margin – UConn can make this interesting if it’s perfect.

Week 2 Schedule, Predictions, Game Preview

What’s Going To Happen

Syracuse is going to air out the passing attack a little bit this week, too.

The less running Tucker and Shrader do, the better – Purdue is up next before the ACC season start.

UConn will play well in the first quarter and hang around early into the second half, but the Syracuse offense will own the clock and the game from then on.

CFN Week 2 Predictions

Syracuse vs UConn Prediction, Line

Syracuse 38, UConn 13
Line: Syracuse -23.5, o/u: 49.5
ATS Confidence out of 5: 3
Syracuse vs UConn Must See Rating (out of 5): 2

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