San Diego Padres at LA Dodgers odds, picks and predictions

Analyzing Thursday’s San Diego Padres at LA Dodgers odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (91-67) and LA Dodgers (94-64) meet Thursday as they wind up a 3-game series in Chavez Ravine. First pitch from Dodger Stadium is slated for 10:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Padres vs. Dodgers odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 8-4

San Diego and LA have split the 1st 2 games of the series. The Dodgers won Wednesday’s contest, snapping a 5-game Padre win streak. Since Sept. 13, San Diego is 9-2.

Los Angeles heads into Thursday’s game leading the Padres in the NL West by 3 games. The Dodgers are a half-game ahead of the Philadelphia Phillies for the top seed in the upcoming NL playoffs.

Padres at Dodgers projected starters

RHP Joe Musgrove vs. RHP Walker Buehler

Musgrove (6-5, 3.95 ERA) is making his 19th start. He has a 1.19 WHIP, 2.1 BB/9 and 9.2 K/9 through 93 1/3 IP.

  • Last outing: No-decision, 6 IP, 0 ER, 4 H, 0 BB, 9 K in 3-2 home win vs. Chicago White Sox Friday
  • Career vs. Dodgers (regular season): 0-7, 4.48 ERA (62 1/3 IP, 31 ER), 1.43 WHIP, 9.0 K/9 in 12 starts

Buehler (1-6, 5.63 ERA) is making his 16th start. He has a 1.58 WHIP, 3.5 BB/9 and 8.1 K/9 through 70 1/3 IP.

  • Last outing: Loss, 5 1/3 IP, 4 ER, 5 H, 1 BB, 9 K in 6-3 home defeat vs. Colorado Rockies Saturday
  • Owns 6.51 ERA over his last 8 starts
  • Career vs. Padres (regular season): 6-1, 1.80 ERA (70 IP, 14 ER), 0.86 WHIP, 10.0 K/9 in 11 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Dodgers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 11:30 a.m. ET.

  • Moneyline: Padres -105 (bet $105 to win $100) | Dodgers -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+165) | Dodgers +1.5 (-200)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Padres at Dodgers picks and predictions

Prediction

Padres 4, Dodgers 3

Moneyline

SAN DIEGO (-105) is 5-2 over its last 7 games at Dodger Stadium.

Musgrove is in excellent form. Over his last 2 starts, he’s held foes scoreless while whiffing 17 batters without issuing a base on balls.

The Friars are an excellent road club (45-31) and are 6-2 across their last 8 away games. Heading into this series, the Padres ranked 5th and 6th, respectively, in road scoring (5.11 runs per game) and run prevention (3.88).

Buehler does not typically get deep into games, and that potentially exposes an LA bullpen which has trended the wrong way this month, at least in its analytic indicator numbers.

BACK PADRES (-105).

Run line/Against the spread

No interest. PASS.

Over/Under

Eight of San Diego’s last 9 games have hit the Under. Across the last 7 San Diego-LA meetings, the Under has gone 5-2.

Look for the starting pitching to be a tad undervalued by surface numbers. TAKE THE UNDER 8.5 (-115).

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San Diego Padres at LA Dodgers odds, picks and predictions

Analyzing Wednesday’s San Diego Padres at LA Dodgers odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (91-66) and LA Dodgers (93-64) meet Wednesday as they continue a 3-game NL West series. The start time at Dodger Stadium is slated for 10:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s MLB odds around the Padres vs. Dodgers odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 8-3

San Diego won Tuesday 4-2 as a +107 underdog. The Padres, 9-1 in the last 10 games, closed out the series-opening win in dramatic fashion, turning a 5-4-3 triple-play to retire LA in the home half of the 9th with DH Shohei Ohtani on deck. The win clinched a postseason berth for the Friars, who are now just 2 games behind the NL West-leading Dodgers.

Los Angeles had been 6-2 with a plus-34 run differential over its last 8 games before Tuesday. The Dodgers have lost 2 in a row at home just twice in the 2nd half.

Padres at Dodgers projected starters

RHP Dylan Cease vs. RHP Jack Flaherty

Cease (14-11, 3.42 ERA) is making his 33rd start. He owns a 1.05 WHIP, 3.0 BB/9 and 10.7 K/9 in 184 1/3 innings.

  • Last outing: Win, 8 1/3 IP, 0 ER, 2 H, 0 BB, 5 K in 4-0 home shutout vs. Houston Astros Sept. 18
  • Career vs. Dodgers: 1-1, 1.72 ERA (15 2/3 IP, 3 ER), 1.40 WHIP, 24 K in 3 starts

Flaherty (13-7, 3.10 ERA) is tabbed for his 28th start combined between the Detroit Tigers and Dodgers. He has authored a 1.06 WHIP, 2.0 BB/9 and 10.8 K/9 through 157 innings between the 2 clubs.

  • Last outing: Win, 6 IP, 3 ER, 5 H, 2 BB, 5 K in 20-4 rout at Miami Marlins Thursday
  • Career vs. Padres (regular season): 2-1, 4.26 ERA (25 1/3 IP, 12 ER), 1.42 WHIP, 28 K in 5 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Dodgers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 4:11 p.m. ET.

  • Moneyline: Padres +120 (bet $100 to win $120) | Dodgers -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-190) | Dodgers -1.5 (+155)
  • Over/Under (O/U): 7.5 (O: -120 | U: +100)

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Padres at Dodgers picks and predictions

Prediction

Padres 5, Dodgers 4

Moneyline

San Diego is 8-2 over its last 10 games against LA.

The Friars are an excellent road club (45-30) and are 6-1 across their last 7 away games. Heading into this series, the Padres ranked 5th and 6th, respectively, in road scoring (5.11 runs per game) and run prevention (3.88).

Wednesday’s pitching matchup is near-level. Looking at recent starts, Cease — who has not allowed a run in his last 2 starts and his last 16 2/3 innings — is a bit more of a green check mark in the mound category.

BACK PADRES (+120).

Run line/Against the spread

No interest. PASS.

Over/Under

Look for both offenses to have just a sliver of an edge in where this one fits compared to expectations. Consider a partial-unit play on OVER 7.5 (-120).

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San Diego Padres at LA Dodgers odds, picks and predictions

Analyzing Tuesday’s San Diego Padres at Los Angeles Dodgers odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (90-66) and LA Dodgers (93-63) meet Tuesday as they open up a 3-game NL West series. Start time in the Tuesday opener is slated for 10:10 p.m. ET (TBS). Let’s analyze BetMGM Sportsbook’s MLB odds around the Padres vs. Dodgers odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 7-3

San Diego is on the road after a 5-1 homestand. The Padres are 8-1 since Sept. 13. Since Sept. 1, they have gained a couple games on Los Angeles in the NL West standings.

The Dodgers, who lead the NL West by 3 games — over the Padres with 6 games to go — are 6-2 with a plus-34 run differential over their last 8 games.

The Southern California foes have played just 2 games since mid-May, and the Friars have won 5 of the last 6 meetings.

Padres at Dodgers projected starters

RHP Michael King vs. RHP Landon Knack

King (12-9, 3.04 ERA) is making his 30th start and 31st appearance. He owns a 1.20 WHIP, 3.3 BB/9 and 10.6 K/9 through 168 2/3 innings.

  • Last outing: No-decision, 7 IP, 2 ER, 5 H, 1 BB, 7 K in 4-3 home loss in 10 innings vs. Houston Astros Sept. 17
  • Road splits: 8-4, 2.80 ERA (90 IP, 28 ER), 1.18 WHIP, 8.9 K/9 in 15 starts and 1 relief outing
  • Career vs. Dodgers: 1-0, 3.63 ERA (17 1/3 IP, 7 ER), 13 H, 8 BB, 23 K in 2 starts and 2 relief appearances
  • 2024 vs. Dodgers: 1-0, 4.11 ERA (15 1/3 IP, 7 ER), 12 H, 8 BB, 20 K in 2 starts and 1 relief appearance
  • Owns a 2.06 ERA (31 1/3 IP, 9 ER) over his last 7 starts

Knack (3-4, 3.39 ERA) is making his 12th start and 14th appearance. The rookie has a 1.07 WHIP, 2.5 BB/9 and 9.0 K/9 in 61 innings.

  • Last outing: Win, 5 IP, 0 ER, 2 H, 2 BB, 7 K in 8-4 win at Miami Marlins Wednesday
  • Home splits: 1-3, 3.00 ERA (30 IP, 10 ER), 0.87 WHIP, 9.3 K/9 in 6 starts
  • Has never faced the Padres

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Dodgers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 3 p.m. ET.

  • Moneyline: Padres +100 (bet $100 to win $100) | Dodgers -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+165) | Dodgers +1.5 (-200)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Padres at Dodgers picks and predictions

Prediction

Padres 6, Dodgers 5

Moneyline

San Diego has won 8 straight series openers. The Padres rank 5th and 6th, respectively in road scoring (5.11 runs per game) and run prevention (3.88).

King has made 10 starts in the 2nd half; he’s allowed more-than-2 earned runs just once. Since 2022, the righty owns a 2.45 ERA, 1.08 WHIP in road starts.

For Knack, strikeout totals (17 in 13 IP) have not been supported by peripherals, and too many baseballs have been barreled up over recent starts. A wind-blowing-out contest in Chavez Ravine has plenty of risk against a Friars club hitting the way it is. San Diego owns a .789 OPS over its last 16 games.

BACK PADRES (+100).

Run line/Against the spread

This play brings more juice and a higher profit hurdle into the equation. AVOID.

Over/Under

The Over is 5-2 across the last 7 series meetings at Dodger Stadium.

Both starting pitchers are solid but overrated by their surface stats. The Padres bullpen fits into the same category when looking at its September numbers, and the LA bullpen has been off its collective game for more than a few weeks.

With an outward breeze in the forecast and 2 good hitting clubs in the batter’s box, BET OVER 8.5 (-105).

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Chicago White Sox at San Diego Padres odds, picks and predictions

Analyzing Sunday’s Chicago White Sox at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (89-66) welcome the Chicago White Sox (36-119) to Petco Park Sunday for the finale of a 3-game series. First pitch is set for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the White Sox at Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 2-0

The Padres beat the White Sox 3-2 to open the series Friday and then continued that streak with a 6-2 win Saturday, closing as heavy favorites in both. They have won 7 of their last 8 games and sit 2nd in the NL West. San Diego is 44-36 at home on the season and 79-76 against the spread (ATS).

The White Sox did sustain a 3-game winning streak Sept. 14-16, but are now riding a 4-game skid. They lost a series 2-1 to the Los Angeles Angels Monday through Wednesday. Chicago, despite that win streak, has still dropped 8 of its last 11 games. It is 16-61 on the road and 63-92 ATS.

White Sox at Padres projected starters

RHP Sean Burke vs. RHP Yu Darvish

Burke (1-0, 2.25 ERA) makes his 2nd start and 3rd appearance. He has a 1.38 WHIP, 3.4 BB/9 and 9.0 K/9 through 8 innings.

  • Last start: Win, 5 IP, 2 ER, 5 H, 2 BB, 5 K in 4-3 home victory over Oakland A’s Sunday
  • 2024 stats with Triple-A Charlotte: 2-6, 4.62 ERA (64 1/3 IP, 33 ER), 1.29 WHIP, 12.0 K/9 in 16 starts
  • Has never faced Padres

Darvish (6-3, 3.21 ERA) makes his 15th start. He has a 1.11 WHIP, 2.4 BB/9 and 8.4 K/9 through 70 innings.

  • Last start: Win, 6 IP, 0 ER, 3 H, 2 BB, 3 K in 3-1 home victory over Houston Astros Monday
  • 2024 home stats: 3-3, 3.75 ERA (48 IP, 20 ER), 1.21 WHIP, 8.3 K/9 in 10 starts
  • Career vs. White Sox: 3-2, 3.57 ERA (45 1/3 IP, 18 ER), 1.30 WHIP, 9.7 K/9 in 7 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

White Sox at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 9:20 a.m. ET.

  • Moneyline (ML): White Sox +280 (bet $100 to win $280) | Padres -350 (bet $350 to win $100)
  • Run line (RL)/Against the spread: White Sox +2.5 (-130) | Padres -2.5 (+110)
  • Over/Under (O/U): 7.5 (O: -120 | U: +100)

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White Sox at Padres picks and predictions

Prediction

Padres 5, White Sox 2

Moneyline

PASS.

The Padres (-350) are again a hefty favorite in this one, so much so that there is no moneyline play. The White Sox are unlikely to avoid a sweep here.

Run line/Against the spread

BET PADRES -2.5 (+110).

The Padres have been winning with ease as of late. They won a series against the Astros 2-1 Monday through Wednesday and swept the San Francisco Giants in 3 games Sept. 13-15.

The White Sox have lost 2 of their last 4 games by more than 2 runs. Chicago has scored a total of 7 runs over its last 4 games and will be facing a strong starting option in Darvish. Expect the Padres to again win by a sizable margin, and take PADRES -2.5 (+110).

Over/Under

BET UNDER 7.5 (+100).

The White Sox haven’t been able to score consistently as of late and have gone Under in 3 of their last 4 games. They are 0-3-1 O/U in that stretch. They are 66-80 O/U on the season. Chicago is 3-8-1 O/U in its last 12.

The Padres have gone Under in 5 of their last 6 games (0-5-1 O/U) and allowed a total of just 4 runs over their last 3.

Take UNDER 7.5 (+100).

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Chicago White Sox at San Diego Padres odds, picks and predictions

Analyzing Friday’s Chicago White Sox at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago White Sox (36-117) open a 3-game series on the road against the San Diego Padres (87-66) Friday night. First pitch from Petco Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the White Sox vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 3-0 last season

The White Sox have only 9 wins since the All-Star break. They have lost 2 in a row after winning 3 straight and are coming off a 4-3 loss at the Los Angeles Angels on Wednesday.

The Padres lead the NL Wild Card race and trail the LA Dodgers by 4 games for the NL West lead. They have won 5 of their last 6 games and are coming off a series-clinching 4-0 win on Wednesday at home over the Houston Astros.

White Sox at Padres projected starters

LHP Garrett Crochet vs. RHP Joe Musgrove

Crochet (6-12, 3.78 ERA) makes his 31st start. He has a 1.09 WHIP, 2.1 BB/9 and 12.7 K/9 in 138 IP.

  • Last start: Loss, 4 IP, 1 ER, 3 H, 0 BB, 4 K in 2-0 home loss to Oakland A’s last Friday
  • Has not had a win since June 7
  • Has not pitched more than 4 IP in last 9 starts
  • Has pitched 1 scoreless inning in his career vs. Padres

Musgrove (6-5, 4.23 ERA) makes his 18th start. He has a 1.23 WHIP, 2.3 BB/9 and 8.9 K/9 in 87 1/3 IP.

  • Last start: Win, 6 IP, 0 R, 3 H, 0 BB,8 K in 8-0 road win over San Francisco Giants on Saturday
  • Is 3-1 with 2.37 ERA in 7 starts since returning from injured list
  • Has 7 1/3 scoreless innings in 3 career games (1 start) vs. Chicago

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

White Sox at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 8:46 a.m. ET.

  • Moneyline (ML): White Sox +200 (bet $100 to win $200) | Padres -250 (bet $250 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-110) | Padres -1.5 (-110)
  • Over/Under (O/U): 7 (O: -110 | U: -110)

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White Sox at Padres picks and predictions

Prediction

Padres 4, White Sox 2

Moneyline

At this point, you should probably never bet on the White Sox on the moneyline. They have the fewest wins in all of baseball. They have only 9 wins since the All-Star Game.

The Padres have won 10 of their last 15, but betting them at -250 isn’t worth the action.

PASS.

Run line/Against the spread

Twelve of Chicago’s last 13 losses have been by at least 2 runs while 10 of the Padres’ last 13 wins have been by 2 or more runs.

The White Sox are 31-44 ATS on the road.

BET PADRES -1.5 (-110).

Over/Under

Six of the Padres’ last 7 games have not reached 8 total runs while 4 of the last 6 for Chicago have not either. Five of their last 8 losses have not either.

Five of Musgrove’s 7 starts since returning from IL had not reached 8 total runs.

BET UNDER 7 (-110).

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Houston Astros at San Diego Padres odds, picks and predictions

Analyzing Wednesday’s Houston Astros at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (82-69) and San Diego Padres (86-66) meet Wednesday for the finale of a 3-game series. First pitch from Petco Park is set for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Astros vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

Houston escaped with a 4-3 win in 10 innings over San Diego Tuesday as a +108 road underdog. After 2B Jose Altuve was ejected in the 9th for taking his shoe off — he was pleading his case that he had fouled a ball off his foot — his replacement Grae Kessinger scored on a 10th-inning, go-ahead RBI single from RF Kyle Tucker.

The loss ended a 4-game win streak for the Padres. San Diego and Houston are essentially playoff locks at this point; their chances of making the postseason are 99.5 and 98.9 percent, respectively, according to FanGraphs.com.

Astros at Padres projected starters

LHP Framber Valdez vs. RHP Dylan Cease

Valdez (14-6, 2.91 ERA) makes his 27th start. He has a 1.09 WHIP, 2.8 BB/9 and 8.7 K/9 through 163 2/3 innings.

  • Last start: No-decision, 6 1/3 IP, 1 ER, 5 H, 1 BB, 6 K in 6-3 home win over Oakland A’s Thursday
  • Career vs. San Diego: 0-1, 4.50 ERA (10 IP, 5 ER), 1.20 WHIP, 7.2 K/9 in 2 starts in 2021

Cease (13-11, 3.58 ERA) makes his 32nd start. He has a 1.09 WHIP, 3.2 BB/9 and 11.0 K/9 through 176 innings.

  • Last start: Win, 6 IP, 0 ER, 4 H, 2 BB, 10 K in 5-0 victory at San Francisco Giants Friday
  • Career vs. Houston (regular season): 0-3, 4.18 ERA (32 1/3 IP, 15 ER), 1.27 WHIP, 9.7 K/9 across 6 starts, including 0-0 with 0.73 ERA (12 1/3 IP, 1 ER) in 2 starts last year

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Astros at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated Wednesday at 9:45 a.m. ET.

  • Moneyline (ML): Astros -115 (bet $115 to win $100) | Padres -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+155) | Padres +1.5 (-190)
  • Over/Under (O/U): 7 (O: -120 | U: +100)

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Astros at Padres picks and predictions

Prediction

Astros 3, Padres 2

Moneyline

LEAN HOUSTON (-115).

Houston is 4-1 in its last 5 road games and 5-1 in its last 6 overall, while the Padres are only 1-3 in their last 4 at home. The Astros are also 3-1 in the last 4 meetings between these teams.

This is a lean because these are 2 very evenly matched squads and the Padres are 3-2 in the last 5 meetings in San Diego.

Run line/Against the spread

PASS.

This should be a tight matchup, as both teams are 6-4 in their last 10 games overall and the last 10 meetings have been split 5-5, so I like the Padres to cover here as +1.5 (-190) underdogs. However, this line is set too favorably to risk betting, so bet the ML and/or total instead.

Over/Under

BET UNDER 7 (+100).

The Under has hit in each of San Diego’s last 3 games overall and is 3-2 in its last 5 at home.

Be aware that the Over is 6-3-1 in the last 10 meetings.

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Houston Astros at San Diego Padres odds, picks and predictions

Analyzing Tuesday’s Houston Astros at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (81-69) face the San Diego Padres (86-65) for the 2nd game of their 3-game series on Tuesday. First pitch from Petco Park is at 9:40 p.m. ET (TruTV). Let’s analyze BetMGM Sportsbook’s MLB odds around the Astros vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 1-0

The Astros lost the opener on Monday 3-1 to snap a 4-game winning streak. The Padres are riding a 4-game winning streak of their own. They are 3 1/2 games behind the NL West-leading LA Dodgers and are in the Wild Card lead.

Astros at Padres projected starters

RHP Hunter Brown vs. RHP Michael King

Brown (11-8, 3.59 ERA) makes his 29th start and 30th appearance. He has a 1.29 WHIP, 3.2 BB/9 and 9.6 K/9 in 158 IP.

  • Last start: Loss, 5 IP, 5 ER, 9 H, 1 BB, 7 K in 5-4 home loss to Oakland A’s on Wednesday
  • In 6 previous starts allowed 2 or fewer ER
  • Is 0-1 with 12.46 ERA in 1 career start vs. Padres

King (12-9, 3.06 ERA) makes his 29th start and 30th appearance. He has a 1.21 WHIP, 3.3 BB/9 and 10.6 K/9 in 161 2/3 IP.

  • Last start: Loss, 5 IP, 3 R (1 ER), 4 H, 2 BB, 6 K in 5-2 road loss to Seattle Mariners on Wednesday
  • Padres 1-3 in his last 4 starts
  • Is 3-1 with 2.61 ERA in 6 career appearances (1 start) vs. Astros

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Astros at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 10:41 a.m. ET.

  • Moneyline (ML): Astros +100 (bet $100 to win $100) | Padres -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+170) | Padres +1.5 (-210)
  • Over/Under (O/U): 7.5 (O: +105 | U: -125)

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Astros at Padres picks and predictions

Prediction

Padres 4, Astros 2

Moneyline

The Padres’ staff has been very good in their winning streak. They have allowed 4 combined runs in 4 games. Their opponents have scored 3 or fewer runs in their last 6 wins. King is 3-1 with a 1.57 ERA in his last 4 starts at Petco.

But be aware the Astros have scored 5 or more runs in 7 of their last 10 games.

BET PADRES (-120). 

Run line/Against the spread

With -210 odds for the Padres to cover the +1.5, there isn’t any need to bed them on the spread. Plus, San Diego’s last 39 covers have been outright wins.

PASS.

Over/Under

Four of the Padres’ last 5 games have not reached 8 total runs and King’s last 3 starts have stayed Under 8 runs.

Seven of the Astros’ last 12 losses have not reached 8 total runs, but they have had 8 of their last 10 games overall go for 8 or more total runs.

BET UNDER 7.5 (-125).

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Houston Astros at San Diego Padres odds, picks and predictions

Analyzing Monday’s Houston Astros at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (81-68) and San Diego Padres (85-65) meet Monday as they swing into a 3-game set. First pitch from Petco Park is slated for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Astros vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Houston won 2-1 in 2023

Houston is continuing a road swing that opened with the club sweeping a 3-game series from the Los Angeles Angels Friday-Sunday. Overall, the Astros have won 4 straight games and 11 of their last 17.

The Padres are back at home after a 4-1 road trip. That short spell away from home concluded with the Friars taking 3 of 3 from the San Francisco Giants over the weekend.

Astros at Padres projected starters

RHP Spencer Arrighetti vs. RHP Yu Darvish

Arrighetti (7-12, 4.72 ERA) is making his 27th start. He has a 1.42 WHIP, 4.2 BB/9 and 10.8 K/9 through 131 2/3 IP.

  • Last outing: No-decision, 6 2/3 IP, 2 ER, 7 H, 1 BB, 7 K in 4-3 home loss vs. Oakland A’s Tuesday
  • Has held opposing batters to .679 OPS while logging 3.31 ERA in 2nd half of season
  • Has never faced Padres

Darvish (5-3, 3.52 ERA) is tabbed for his 14th start. He owns a 1.14 WHIP, 2.4 BB/9 and 8.7 K/9 in 64 IP.

  • Last outing: Win, 5 IP, 2 ER, 7 H, 0 BB, 5 K in 7-3 win at Seattle Mariners Tuesday
  • Career vs. Astros (regular season): 5-5, 3.64 ERA (94 IP, 38 ER), 1.09 WHIP, 11.8 K/9 in 15 starts
  • Making his 3rd start since returning from IL stint (elbow) Sept. 4

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Astros at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 10:50 a.m. ET.

  • Moneyline: Astros +105 (bet $100 to win $105) | Padres -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros +1.5 (-210) | Padres -1.5 (+170)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Astros at Padres picks and predictions

Prediction

Astros 4, Padres 3

Moneyline

HOUSTON (+105) is 14-4 over its last 18 games against the NL West.

The Astros have inexplicably gone just 15-26 in 1-run games and 5-10 in extra-inning contests. They have underplayed their 4.63 runs per game and 4.00 RPG allowed and should be a lean in few games down the stretch.

That lean gets pushed out with this mound matchup. Arrighetti has been quite good. He has the look of a 27-year-old putting things together, and he owns a tidy 3.06 ERA over his last 6 road starts. His rest interval fits as a green check mark also. Arrighetti has scuffled with long rest and on 4-day rest. His 5-day (applicable for this start) interval figures: 3.58 ERA with 3.3 K/BB.

San Diego is just 5-6 over its last 11 games at home. Peg the ASTROS (+105) as the value play.

Run line/Against the spread

PASS on bringing all the juice into play on this RL offering.

Over/Under

The Under has cashed in 6 of Houston’s last 9 games and in 11 of the club’s last 16 on the road.

Arrighetti’s prognosis applies some downward pressure here. Add in a cool-weather evening and 2 first-division bullpens. TAKE THE UNDER 8 (-115).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Saturday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (83-65) face the San Francisco Giants (72-76) in the 2nd game of their 3-game series Saturday. First pitch from Oracle Park is at 9:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 6-5.

The Padres won the opener Friday night 5-0 and retook the Wild Card lead over the Arizona Diamondbacks by a half game. They are 6-4 in  their last 10 games.

The Giants were shut out for the 2nd straight game Friday and have lost 3 of their last 4 games. They are 4-8 in their last 12 games.

Padres at Giants projected starters

RHP Joe Musgrove vs. RHP Mason Black

Musgrove (5-5, 4.54 ERA) makes his 17th start. He has a 1.28 WHIP, 2.4 BB/9 and 8.6 K/9 through 81 1/3 innings.

  • Last start: Loss, 4 1/3 IP, 6 ER, 8 H, 1 BB, 7 K in 7-6 home loss to the Giants Sunday
  • Had allowed only 4 ER in previous 5 starts combined
  • 4-5 with 4.46 ERA in 15 career starts vs. Giants

Black (0-3, 7.50 ERA) makes his 6th start and 7th appearance. He has a 1.63 WHIP, 3.0 BB/9 and 8.3 K/9 through 24 innings.

  • Last start: Loss, 4 2/3 IP, 4 ER, 6 H, 1 BB, 6 K in 5-1 road loss to the Padres last Friday, his only career game against the them
  • Has allowed 4+ ER in 3 of 5 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 12:40 p.m. ET.

  • Moneyline (ML): Padres -160 (bet $160 to win $100) | Giants +135 (bet $100 to win $135)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+105) | Giants +1.5 (-125)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Padres at Giants picks and predictions

Prediction

Padres 5, Giants 2

Moneyline

The Giants have scored 2 or fewer runs in their last 4 losses. They beat Musgrove last week, but Black has not been great thus far,

Musgrove got lit up for 6 runs in his last start, but his ERA was 1.16 in his previous 4.

He will bounce back, but the run line is the better bet for the Padres.

PASS. 

Run line/Against the spread

Seven of the Padres’ last 9 wins have been by more than 1 run. All 5 of their wins over the Giants this season have been by 2+ runs.

Seven of the Giants’ last 10 losses have been my multiple runs.

BET PADRES -1.5 (+105). 

Over/Under

Six of the 11 games they have played against each other this season have had 8 or more runs.

The Giants’ last 4 losses have not reached 8 total runs.

Six of the Padres’ last 10 games have not reached 8 total runs.

BET UNDER 7.5 (-105). 

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Friday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (82-65) and San Francisco Giants (72-75) open a 3-game series Friday. First pitch from Oracle Park is at 10:15 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 6-4

The Padres were off Thursday after Wednesday’s 5-2 loss at the Seattle Mariners for a 2-game series split. They have lost 3 of their last 4 games and trail the Arizona Diamondbacks by a half-game for the top NL Wild Card spot.

The Giants are coming off a 2-1 series loss to the visiting Milwaukee Brewers, dropping the Thursday finale 3-0. They are 4-7 in their last 11 games.

Padres at Giants projected starters

RHP Dylan Cease vs. RHP Logan Webb

Cease (12-11, 3.71 ERA) makes his 31st start. He has a 1.09 WHIP, 3.2 BB/9 and 10.9 K/9 through 170 innings.

  • Last start: Loss, 6 IP, 4 ER, 6 H, 2 BB, 4 K in 6-3 home defeat to Giants Saturday; Webb was San Francisco’s starter
  • 2024 vs. Giants: 0-2, 4.32 ERA (16 2/3 IP, 8 ER), 1.08 WHIP, 9.2 K/9 in 3 starts
  • Career vs. Giants: 2-2, 3.38 ERA (26 2/3 IP, 10 ER), 1.16 WHIP, 9.8 K/9 in 5 starts

Webb (12.9, 3.46 ERA) makes his 31st start. He has a 1.23 WHIP, 2.2 BB/9 and 7.4 K/9 through 189 2/3 innings.

  • Last start: Win, 6 IP, 3 ER, 10 H, 2 BB, 3 K Saturday
  • 2024 vs. Padres: 1-0, 3.32 ERA (19 IP, 7 ER), 1.53 WHIP, 5.2 K/9 in 3 starts
  • Career vs. Padres: 4-2, 2.70 ERA (76 2/3 IP, 23 ER), 1.19 WHIP, 7.2 K/9 in 13 appearances (12 starts)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 11 a.m. ET.

  • Moneyline (ML): Padres -115 (bet $115 to win $100) | Giants -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+155) | Giants +1.5 (-190)
  • Over/Under (O/U): 7 (O: -105 | U: -115)

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Padres at Giants picks and predictions

Prediction

Giants 5, Padres 3

Moneyline

The GIANTS (-105) are 6-2 in Webb’s last 8 starts. They took 2 out of 3 games last weekend in San Diego over the Padres. They have held opponents to 3 or fewer runs in 5 of their last 7 games.

The Padres are 2-7 in their last 9 games when they allow 4 or more runs.

The Giants have scored 4 or more in 6 of their last 10 games.

BET GIANTS (-105).

Run line/Against the spread

The Giants are 4-1 ATS in their last 5 games. The Padres are 4-9 ATS in their last 13 games.

The Padres are 14-17 ATS as road favorites.

But If you like the Giants +1.5, the -190 odds aren’t it. With -105 odds for them to win outright, go with the ML.

PASS.

Over/Under

Six of 10 games between the 2 teams have had more than 7 total runs.

Seven of the Giants’ last 11 games have had at least 7 total runs. Webb’s last 4 starts have all had more than 7 total runs.

Nine of the last 11 for the Padres have had totals of 7 or more.

BET OVER 7 (-105).

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

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