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The San Diego Padres (82-65) and San Francisco Giants (72-75) open a 3-game series Friday. First pitch from Oracle Park is at 10:15 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.
Season series: Giants lead 6-4
The Padres were off Thursday after Wednesday’s 5-2 loss at the Seattle Mariners for a 2-game series split. They have lost 3 of their last 4 games and trail the Arizona Diamondbacks by a half-game for the top NL Wild Card spot.
The Giants are coming off a 2-1 series loss to the visiting Milwaukee Brewers, dropping the Thursday finale 3-0. They are 4-7 in their last 11 games.
Padres at Giants projected starters
RHP Dylan Cease vs. RHP Logan Webb
Cease (12-11, 3.71 ERA) makes his 31st start. He has a 1.09 WHIP, 3.2 BB/9 and 10.9 K/9 through 170 innings.
- Last start: Loss, 6 IP, 4 ER, 6 H, 2 BB, 4 K in 6-3 home defeat to Giants Saturday; Webb was San Francisco’s starter
- 2024 vs. Giants: 0-2, 4.32 ERA (16 2/3 IP, 8 ER), 1.08 WHIP, 9.2 K/9 in 3 starts
- Career vs. Giants: 2-2, 3.38 ERA (26 2/3 IP, 10 ER), 1.16 WHIP, 9.8 K/9 in 5 starts
Webb (12.9, 3.46 ERA) makes his 31st start. He has a 1.23 WHIP, 2.2 BB/9 and 7.4 K/9 through 189 2/3 innings.
- Last start: Win, 6 IP, 3 ER, 10 H, 2 BB, 3 K Saturday
- 2024 vs. Padres: 1-0, 3.32 ERA (19 IP, 7 ER), 1.53 WHIP, 5.2 K/9 in 3 starts
- Career vs. Padres: 4-2, 2.70 ERA (76 2/3 IP, 23 ER), 1.19 WHIP, 7.2 K/9 in 13 appearances (12 starts)
Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.
Padres at Giants odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 11 a.m. ET.
- Moneyline (ML): Padres -115 (bet $115 to win $100) | Giants -105 (bet $105 to win $100)
- Run line (RL)/Against the spread (ATS): Padres -1.5 (+155) | Giants +1.5 (-190)
- Over/Under (O/U): 7 (O: -105 | U: -115)
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Padres at Giants picks and predictions
Prediction
Giants 5, Padres 3
Moneyline
The GIANTS (-105) are 6-2 in Webb’s last 8 starts. They took 2 out of 3 games last weekend in San Diego over the Padres. They have held opponents to 3 or fewer runs in 5 of their last 7 games.
The Padres are 2-7 in their last 9 games when they allow 4 or more runs.
The Giants have scored 4 or more in 6 of their last 10 games.
BET GIANTS (-105).
Run line/Against the spread
The Giants are 4-1 ATS in their last 5 games. The Padres are 4-9 ATS in their last 13 games.
The Padres are 14-17 ATS as road favorites.
But If you like the Giants +1.5, the -190 odds aren’t it. With -105 odds for them to win outright, go with the ML.
PASS.
Over/Under
Six of 10 games between the 2 teams have had more than 7 total runs.
Seven of the Giants’ last 11 games have had at least 7 total runs. Webb’s last 4 starts have all had more than 7 total runs.
Nine of the last 11 for the Padres have had totals of 7 or more.
BET OVER 7 (-105).
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