Pittsburgh Pirates at San Francisco Giants odds, picks and predictions

Analyzing Wednesday’s Pittsburgh Pirates at San Francisco Giants odds and lines, with expert MLB picks, predictions and best bets.

The Pittsburgh Pirates (27-27) wrap up a 3-game series with the San Francisco Giants (28-27) Wednesday at Oracle Park. First pitch is scheduled for 3:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Pirates vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: tied 1-1

The Pirates halted a 3-game losing skid with a 2-1 victory vs. the Giants in the middle game of the series Tuesday night. It was a well-pitched game, which was in stark contrast to a 14-4 setback in the series opener on Memorial Day.

Pittsburgh is still just 7-19 in the past 26 games overall, cashing in just 2 of the past 7 games on the road. The Bucs haven’t been good at stacking wins, going just 1-6 in the past 7 outings after a victory.

The Giants have alternated losses and wins in the past 4 games. Plating just 1 run Tuesday was a disappointment, as the wind was blowing out to left-center field and the Giants had managed 42 runs in the 5 games prior to the setback.

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Pirates at Giants projected starters

RHP Mitch Keller vs. LHP Alex Wood

Keller (6-1, 3.01 ERA) makes his 12th start. He has a 1.02 WHIP, 2.1 BB/9 and 11.1 K/9 in 68 2/3 innings.

  • Last start: Win, 6 IP, 6 ER, 7 H, 2 BB, 8 K in an 11-6 road win vs. the Seattle Mariners Friday
  • 2023 Road splits: 3-1, 3.79 ERA (35 2/3 IP, 15 ER) with a .230 opponent batting average (OBA) in 6 starts

Wood (1-0, 3.51 ERA) makes his 7th start and 8th overall appearance. He has a 1.44 WHIP, 4.6 BB/9 and 9.1 K/9 in 25 2/3 innings.

  • Last start: Win, 5 2/3 IP, 1 ER, 3 H, 5 BB, 5 K in a 15-1 road win vs. the Milwaukee Brewers Friday
  • 2023 Home splits: 0-0, 3.95 ERA (13 2/3 IP, 6 ER) with 4 BB, 14 K and a .212 OBA in 3 starts

Pirates at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:10 a.m. ET.

  • Moneyline (ML): Pirates +105 (bet $100 to win $105) | Giants -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Pirates +1.5 (-210) | Giants -1.5 (+170)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Pirates at Giants picks and predictions

Prediction

Giants 4, Pirates 3

Moneyline

The GIANTS (-125) are worth playing in the getaway day game.

Both pitchers have been tremendous to start the season, and like we saw Tuesday, even if the wind is blowing out briskly to the power alley in left-center field, good pitchers can still keep the ball in the yard.

The Bucs have failed to win in 6 of their past 7 tries following a victory, and Tuesday’s win was their first in 6 tries at Oracle Park.

Run line/Against the spread

The Pirates +1.5 (-210) will cost you over 2 times your potential return, if you require a little bit of insurance, and just cannot bring yourself to play Pittsburgh straight up.

AVOID.

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Over/Under

The UNDER 7.5 (-105) is worth a look in this day game on the Bay.

Keller seems to enjoy pitching in the daytime, allowing just 12 ER in 36 2/3 innings under the sun while allowing a .206 OBA.

The Under is 17-8-1 in the past 26 games during Game 3 of a series for Pittsburgh, while going 4-1 in the past 5 following a win.

The Under is 3-1-1 in San Francisco’s past 5 home games against a right-handed starting pitcher, too.

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MLB best bets: Pittsburgh Pirates at San Francisco Giants game predictions

Analyzing Friday’s Pittsburgh Pirates at San Francisco Giants odds and lines, with expert MLB betting picks and predictions.

The San Francisco Giants (61-35) start a three-game set with the visiting Pittsburgh Pirates (36-60) Friday at Oracle Park. First pitch is scheduled for 9:45 p.m. ET. Let’s analyze BetMGM Sportsbook‘s lines around the Pirates vs. Giants odds with MLB picks and predictions.

Season series: Tied 2-2.

RHP Chad Kuhl is on the bump for the Pirates. He is 3-5 with a 4.31 ERA (56 1/3 IP, 27 ER), 1.37 WHIP, 5.3 BB/9 and 7.2 K/9 across 12 starts.

  • Last outing: Win, 4-1, with 5 IP, 0 ER, 2 H, 5 BB and 3 K last Friday against the New York Mets.
  • 2021 road stats: 1-4 with a 6.07 ERA (29 2/3 IP, 20 ER), 1.55 WHIP and 1.5 K/BB rate through seven starts.

RHP Johnny Cueto is San Francisco’s projected starter. He is 6-5 with a 4.01 ERA (83 IP, 37 ER), 1.29 WHIP, 1.7 BB/9 and 7.6 K/9 over 15 starts.

  • Last outing: No-decision with 5 IP, 1 ER, 2 H, 1 BB and 5 K in San Francisco’s 2-1 loss at the St. Louis Cardinals Sunday.
  • Cueto earned a no-decision against Pittsburgh May 15, with 4 1/3 IP, 2 ER, 8 H, 0 BB and 2 K in San Francisco’s 8-6 road loss.
    • vs. Pirates on the current roster (44 PA): 2.40 FIP with a .268 batting average, .277 wOBA, .438 expected slugging percentage, 15.9 K% and 86.5 mph exit velocity.

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Pirates at Giants odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 2 p.m. ET.

  • Money line: Pirates +155 (bet $100 to win $155) | Giants -190 (bet $190 to win $100)
  • Against the spread/ATS: Pirates +1.5 (-130) | Giants -1.5 (+105)
  • Over/Under: 8 (O: -115 | U: -105)

Prediction

Giants 4, Pirates 1

Money line (ML)

“LEAN” to the GIANTS (-190) because they are better than the Pirates in every facet of the game and San Francisco has the best winning percentage both at home and against right-handed starters.

However, these things are already baked into the line and close to 90% of the cash wagered is on the Giants, according to Pregame.com.

Their money line is a little pricier than I’d like with Cueto on the bump; however, this isn’t the NFL where the “any given Sunday” mantra applies and there’s an ocean-sized gap between these two sides.

That said, I’d play it safe here and risk only 1 unit on San Francisco’s money line. As in, if your standard wager is $100, put that on the GIANTS (-190) to earn a profit of $52.63.

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Run line/Against the spread (ATS)

BET the GIANTS -1.5 (+105) based on all the previous analysis combined with San Francisco having the second-best cover rate as a home favorite with a 20-14 ATS record. Pittsburgh has the second-worst cover rate on the road at 19-30 ATS.

Personally, I’ll be greedy and take San Francisco’s run line instead of the money line to go for a bigger payout but, either way, the Giants are the right side in this contest.

Over/Under (O/U)

PASS with a slight “lean” to the Under 8 (-105) because three of the four Pirates-Giants meetings went Under the total and San Francisco is 5-9 O/U when Cueto gets the start.

However, the Pirates are 8-4 O/U in games Kuhl starts and I’m even less confident in Pittsburgh’s bullpen than Kuhl.

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