Pittsburgh Pirates at San Francisco Giants odds, picks and predictions

Analyzing Wednesday’s Pittsburgh Pirates at San Francisco Giants odds and lines, with expert MLB picks, predictions and best bets.

The Pittsburgh Pirates (27-27) wrap up a 3-game series with the San Francisco Giants (28-27) Wednesday at Oracle Park. First pitch is scheduled for 3:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Pirates vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: tied 1-1

The Pirates halted a 3-game losing skid with a 2-1 victory vs. the Giants in the middle game of the series Tuesday night. It was a well-pitched game, which was in stark contrast to a 14-4 setback in the series opener on Memorial Day.

Pittsburgh is still just 7-19 in the past 26 games overall, cashing in just 2 of the past 7 games on the road. The Bucs haven’t been good at stacking wins, going just 1-6 in the past 7 outings after a victory.

The Giants have alternated losses and wins in the past 4 games. Plating just 1 run Tuesday was a disappointment, as the wind was blowing out to left-center field and the Giants had managed 42 runs in the 5 games prior to the setback.

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Pirates at Giants projected starters

RHP Mitch Keller vs. LHP Alex Wood

Keller (6-1, 3.01 ERA) makes his 12th start. He has a 1.02 WHIP, 2.1 BB/9 and 11.1 K/9 in 68 2/3 innings.

  • Last start: Win, 6 IP, 6 ER, 7 H, 2 BB, 8 K in an 11-6 road win vs. the Seattle Mariners Friday
  • 2023 Road splits: 3-1, 3.79 ERA (35 2/3 IP, 15 ER) with a .230 opponent batting average (OBA) in 6 starts

Wood (1-0, 3.51 ERA) makes his 7th start and 8th overall appearance. He has a 1.44 WHIP, 4.6 BB/9 and 9.1 K/9 in 25 2/3 innings.

  • Last start: Win, 5 2/3 IP, 1 ER, 3 H, 5 BB, 5 K in a 15-1 road win vs. the Milwaukee Brewers Friday
  • 2023 Home splits: 0-0, 3.95 ERA (13 2/3 IP, 6 ER) with 4 BB, 14 K and a .212 OBA in 3 starts

Pirates at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:10 a.m. ET.

  • Moneyline (ML): Pirates +105 (bet $100 to win $105) | Giants -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Pirates +1.5 (-210) | Giants -1.5 (+170)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Pirates at Giants picks and predictions

Prediction

Giants 4, Pirates 3

Moneyline

The GIANTS (-125) are worth playing in the getaway day game.

Both pitchers have been tremendous to start the season, and like we saw Tuesday, even if the wind is blowing out briskly to the power alley in left-center field, good pitchers can still keep the ball in the yard.

The Bucs have failed to win in 6 of their past 7 tries following a victory, and Tuesday’s win was their first in 6 tries at Oracle Park.

Run line/Against the spread

The Pirates +1.5 (-210) will cost you over 2 times your potential return, if you require a little bit of insurance, and just cannot bring yourself to play Pittsburgh straight up.

AVOID.

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Over/Under

The UNDER 7.5 (-105) is worth a look in this day game on the Bay.

Keller seems to enjoy pitching in the daytime, allowing just 12 ER in 36 2/3 innings under the sun while allowing a .206 OBA.

The Under is 17-8-1 in the past 26 games during Game 3 of a series for Pittsburgh, while going 4-1 in the past 5 following a win.

The Under is 3-1-1 in San Francisco’s past 5 home games against a right-handed starting pitcher, too.

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Pittsburgh Pirates at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s Pittsburgh Pirates at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

The Pittsburgh Pirates (26-27) and San Francisco Giants (28-26) face each other Tuesday for the 2nd game of a 3-game series. First pitch is scheduled for 9:45 p.m. ET at Oracle Park (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Pirates vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0

The Giants won the series opener 14-4 on Monday behind C Patrick Bailey’s 2-run homer and 2-run double. San Francisco has won 11 of their last 14 games.

The Pirates have lost 3 in a row and 5 of their last 6 games overall. They are 6-19 in their last 25 games.

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Pirates at Giants projected starters

RHP Johan Oviedo vs. RHP John Brebbia

Oviedo (3-4, 4.70 ERA) makes his 11th start. He has a 1.53 WHIP, 4.2 BB/9 and 8.0 K/9 in 53 2/3 innings.

  • Pirates are 1-5 in his last 6 starts
  • Has 2.70 ERA in last 3 starts (16 2/3 IP)

Brebbia (2-0, 3.68 ERA) makes his 24th appearance (and 4th  start). He has a 1.09 WHIP, 2.9 BB/9 and 12.7 K/9 in 22 innings.

  • Has not allowed a run in 3 other openers (3 1/3 IP)
  • Has not allowed a run in last 7 appearances

Pirates at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:53 a.m. ET.

  • Moneyline (ML): Pirates +120 (bet $100 to win $120) | Giants -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Pirates +1.5 (-165) | Giants -1.5 (+140)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Pirates at Giants picks and predictions

Prediction

Giants 6, Pirates 4

Moneyline

The Pirates have only 6 wins in their last 25 games while the Giants have 11 wins in their last 14.

The Pirates have been held to 3 runs or fewer in 6 of their last 8 games.

The Giants will rely on their bullpen in this game. Their bullpen ERA this year is 4.48.

While the line for the Giants on the moneyline isn’t bad, the run line is better and trends favor going with that bet.

PASS.

Run line/Against the spread

Of the Giants’ last 15 wins, 12 have been by more than 1 run while the Pirates have lost by 2 or more runs in 15 of their last 19 losses.

BET GIANTS -1.5 (+140).

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Over/Under

For both teams, 3 of their last 4 games have had had more than 8 total runs. They combined for 18 runs in Monday’s opener. Also, in 2 of Brebbia’s 3 openers, the total surpassed 8 runs.

BET OVER 8.5 (-115).

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Pittsburgh Pirates at San Francisco Giants odds, picks and predictions

Analyzing Monday’s Pittsburgh Pirates at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

The Pittsburgh Pirates (26-26) open a 3-game series against the San Francisco Giants (27-26) Monday. First pitch from Oracle Park is at 5:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Pirates vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting

The Pirates have lost 6 of their last 8 games and have started a 6-game road trip by dropping 2 of 3 at the Seattle Mariners over the weekend. Pittsburgh won the series opener but lost 6-3 in 10 innings Sunday and 5-0 Saturday.

The Giants failed to complete the sweep of a 4-game series over the Milwaukee Brewers with a 7-5 loss Sunday. San Francisco returns home after winning 5 games across a 7-game road trip last week.

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Pirates at Giants projected starters

LHP Rich Hill vs. RHP Anthony DeSclafani

Hill (4-4, 4.27 ERA) makes his 11th start. He has a 1.39 WHIP, 2.9 BB/9 and 8.9 K/9 through 52 2/3 IP.

  • Last start: Loss, 5 1/3 IP, 5 ER, 7 H, 2 BB, 9 K in a 6-1 loss vs. the Texas Rangers Tuesday
  • Career vs. Giants: 8-2 with a 2.34 ERA across 18 starts

DeSclafani (3-4, 3.43 ERA) makes his 11th start. He has a 1.04 WHIP, 1.3 BB/9 and 7.0 K/9 through 60 1/3 IP.

  • 0-3 with a 5.64 ERA over his last 4 starts
  • Career vs. Pirates: 3-7 with a 5.13 ERA across 17 starts

Pirates at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:07 a.m. ET.

  • Moneyline (ML): Pirates +115 (bet $100 to win $115) | Giants -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Pirates +1.5 (-175) | Giants -1.5 (+145)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Pirates at Giants picks and predictions

Prediction

Pirates 4, Giants 3

Moneyline

The Pirates have won their last 2 series openers they have played and then have lost 2 in a row. They are 14-13 on the road this season and Hill has had great career success against the Giants.

San Francisco is 10-3 in its last 13 games and DeSclafani has not been as effective in his last 4 starts and has struggled throughout his career against the Pirates.

If there is a game in this series to pick the underdog Pirates to win, it is this one.

BET PIRATES (+115).

Run line/Against the spread

The Pirates are 27-25 ATS on the season while the Giants are 27-26 ATS.

The Pirates are 21-18 ATS as the underdog, but betting them on the moneyline is far more profitable. Of the last 6 games they covered, they won 5 of them outright.

PASS.

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Over/Under

Four of the 6 games these teams played against each other last season had totals of fewer than 9 runs.

Ten of the Pirates’ last 17 games have had 8 or fewer total runs.

Five of the Giants’ last 7 outings have had 8 or fewer.

BET UNDER 8.5 (-115).

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MLB best bets: Pittsburgh Pirates at San Francisco Giants game predictions

Analyzing Friday’s Pittsburgh Pirates at San Francisco Giants odds and lines, with expert MLB betting picks and predictions.

The San Francisco Giants (61-35) start a three-game set with the visiting Pittsburgh Pirates (36-60) Friday at Oracle Park. First pitch is scheduled for 9:45 p.m. ET. Let’s analyze BetMGM Sportsbook‘s lines around the Pirates vs. Giants odds with MLB picks and predictions.

Season series: Tied 2-2.

RHP Chad Kuhl is on the bump for the Pirates. He is 3-5 with a 4.31 ERA (56 1/3 IP, 27 ER), 1.37 WHIP, 5.3 BB/9 and 7.2 K/9 across 12 starts.

  • Last outing: Win, 4-1, with 5 IP, 0 ER, 2 H, 5 BB and 3 K last Friday against the New York Mets.
  • 2021 road stats: 1-4 with a 6.07 ERA (29 2/3 IP, 20 ER), 1.55 WHIP and 1.5 K/BB rate through seven starts.

RHP Johnny Cueto is San Francisco’s projected starter. He is 6-5 with a 4.01 ERA (83 IP, 37 ER), 1.29 WHIP, 1.7 BB/9 and 7.6 K/9 over 15 starts.

  • Last outing: No-decision with 5 IP, 1 ER, 2 H, 1 BB and 5 K in San Francisco’s 2-1 loss at the St. Louis Cardinals Sunday.
  • Cueto earned a no-decision against Pittsburgh May 15, with 4 1/3 IP, 2 ER, 8 H, 0 BB and 2 K in San Francisco’s 8-6 road loss.
    • vs. Pirates on the current roster (44 PA): 2.40 FIP with a .268 batting average, .277 wOBA, .438 expected slugging percentage, 15.9 K% and 86.5 mph exit velocity.

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Pirates at Giants odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 2 p.m. ET.

  • Money line: Pirates +155 (bet $100 to win $155) | Giants -190 (bet $190 to win $100)
  • Against the spread/ATS: Pirates +1.5 (-130) | Giants -1.5 (+105)
  • Over/Under: 8 (O: -115 | U: -105)

Prediction

Giants 4, Pirates 1

Money line (ML)

“LEAN” to the GIANTS (-190) because they are better than the Pirates in every facet of the game and San Francisco has the best winning percentage both at home and against right-handed starters.

However, these things are already baked into the line and close to 90% of the cash wagered is on the Giants, according to Pregame.com.

Their money line is a little pricier than I’d like with Cueto on the bump; however, this isn’t the NFL where the “any given Sunday” mantra applies and there’s an ocean-sized gap between these two sides.

That said, I’d play it safe here and risk only 1 unit on San Francisco’s money line. As in, if your standard wager is $100, put that on the GIANTS (-190) to earn a profit of $52.63.

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Run line/Against the spread (ATS)

BET the GIANTS -1.5 (+105) based on all the previous analysis combined with San Francisco having the second-best cover rate as a home favorite with a 20-14 ATS record. Pittsburgh has the second-worst cover rate on the road at 19-30 ATS.

Personally, I’ll be greedy and take San Francisco’s run line instead of the money line to go for a bigger payout but, either way, the Giants are the right side in this contest.

Over/Under (O/U)

PASS with a slight “lean” to the Under 8 (-105) because three of the four Pirates-Giants meetings went Under the total and San Francisco is 5-9 O/U when Cueto gets the start.

However, the Pirates are 8-4 O/U in games Kuhl starts and I’m even less confident in Pittsburgh’s bullpen than Kuhl.

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