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The San Francisco Giants (29-27) welcome the Philadelphia Phillies (38-18) to Oracle Park Wednesday. First pitch in the final of their 3-game series is set for 3:45 p.m.ET. Let’s analyze FanDuel Sportsbook’s lines around the Phillies vs. Giants odds and make our expert MLB picks and predictions for the best bets.
Season series: Phillies lead 4-2
The Phillies swept the Giants in a 4-game series earlier in the season, but the Giants have won the last 2. San Francisco won 8-4 Monday and 1-0 Tuesday, closing as a +173 underdog in the latter of the 2 games. The Giants have won 6 of their last 7 games and are 10-2 over their last 12. San Francisco is a strong 17-10 at home this season.
The Phillies, who are 16-10 on the road, are riding a 3-game losing streak. Only 2 other times this season have they lost even back-to-back games, and their current 3-game streak is their longest losing streak this season. Philadelphia is still 7-4 straight up over its last 11 games and is 31-25 ATS on the season.
Phillies at Giants projected starters
LHP Cristopher Sanchez vs. LHP Kyle Harrison
Sanchez (2-3, 3.15 ERA) makes his 11th start. He has a 1.45 WHIP, 3.1 BB/9 and 8.1 K/9 in 54 1/3 IP.
- Last start: No-decision, 5 1/3 IP, 1 ER, 7 H, 1 BB, 2 K in a 3-2 road loss to the Colorado Rockies Friday
- 2024 road splits: 0-2, 4.63 ERA (23 1/3 IP, 12 ER), 31 H, 1 HR, 12 BB, 12 K in 5 starts
- Career vs. Giants: 0-0, 1.93 ERA (9 IP, 4 ER), 0.89 WHIP, 7.0 K/9 in 1 start and 1 relief appearance
Harrison (4-1, 3.90 ERA) makes his 12th start. He has a 1.30 WHIP, 3.2 BB/9 and 8.3 K/9 in 60 IP.
- Last start: No-decision, 5 IP, 4 ER, 6 H, 2 BB, 6 K in an 8-7 road win over the New York Mets Friday
- 2024 home splits: 1-0, 4.15 ERA (26 IP, 12 ER), 24 H, 1 HR, 8 BB, 29 K in 5 starts
- Career vs. Phillies: 0-0, 5.40 ERA (3 1/3 IP, 2 ER), 1.80 WHIP, 13.5 K/9 in 1 start, a 4-3 road loss in his career debut on Aug. 22, 2023
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Phillies at Giants odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:07 a.m. ET.
- Moneyline (ML): Phillies -132 (bet $132 to win $100) | Giants +112 (bet $100 to win $112)
- Run line (RL)/Against the spread (ATS): Phillies -1.5 (+132) | Giants +1.5 (-160)
- Over/Under (O/U): 7.5 (O: -120 | U: -102)
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Phillies at Giants picks and predictions
Prediction
Phillies 5, Giants 3
Moneyline
BET PHILLIES (-132).
The Phillies are one of the best teams in the MLB, and they have won 3 of the last 4 games in which Sanchez has started. They are on an uncharacteristically long losing streak, and that should be snapped here.
The Giants are hot, and they have won 3 straight with Harrison starting. However, they have allowed 16 runs as a team through those 3 games and have scored 3 or fewer in 2 of their last 3.
Considering their struggling bats and the Giants inability to keep runners off the bases with Harrison on the mound, back PHILLIES (-132) to snap their season-long losing streak.
Run line/Against the spread
PASS.
Neither value here is great. The Giants are hot and have won 3 in a row with Harrison. And while the Phillies have performed well with Sanchez on the mound, 2 of those 3 wins were by 1 run. They are too risky to play as a run-line favorite.
Over/Under
LEAN OVER 7.5 (-120).
The Giants have gone Over in 6 of their last 8 games and are 29-25-2 O/U on the season. They have scored at least 6 runs in 6 of their last 8.
Philadelphia is 27-26-3 O/U and has traded off going Over and Under in its last 5 games. It is primed to go Over after a 1-0 defeat Tuesday. Back OVER 7.5 (-120).
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