Baltimore Orioles at Cleveland Guardians odds, picks and predictions

Analyzing Saturday’s Baltimore Orioles at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (65-46) and Cleveland Guardians (67-42) play the 3rd contest of a 4-game series Saturday. First pitch from Progressive Field is at 7:15 p.m. ET (FOX). Let’s analyze FanDuel Sportsbook’s lines around the Orioles vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 4-1

The Guardians doubled up the Orioles 8-4 in Friday’s game, and Cleveland has now outscored Baltimore 18-7 in the first 2 games of the series.

The Guards have won 5 in a row, averaging 7.0 runs per game (RPG) during the span, while allowing just 2.8 RPG. The Over is 3-1 in the past 4 contests, too.

The O’s have dropped 3 of the past 5 games while going a dismal 5-8 across the previous 13 outings. The Over has connected in both games of this series, and the total has gone high at an 11-1 clip in the past 12 contests while going 14-2 in the past 16 outings.

Orioles at Guardians projected starters

RHP Zach Eflin vs. LHP Joey Cantillo

Eflin (6-7, 4.11 ERA) makes his 21st start. He has a 1.19 WHIP, 1.0 BB/9 and 7.3 K/9 in 116 IP with the Tampa Bay Rays and Orioles.

  • Last start: Win, 6 IP, 3 ER, 10 H (1 HR), 0 BB, 7 K in 11-5 home victory vs. Toronto Blue Jays in his team debut Monday
  • 2024 road splits: 2-5, 5.32 ERA (66 IP, 39 ER), 1.30 WHIP, .285 opponents’ batting average, 9 BB, 54 K in 8 starts with Rays
  • Career vs. Guardians: 0-1, 18.00 ERA (3 IP, 6 ER), 9 H, 1 BB, 3 K in 1 start, a 9-2 home loss Aug. 13, 2023, with Rays

Cantillo (0-0, 8.10 ERA) makes his 2nd career start. He allowed 3 earned runs on 4 hits and 3 walks with 3 K’s in 3 1/3 innings in his debut, a 4-3 victory at the Philadelphia Phillies Sunday.

  • 2024 stats with Triple-A Columbus: 1-1, 2.79 ERA (29 IP, 9 ER), 1.48 WHIP, 12.1 K/9 in 8 appearances (7 starts)
  • Is starting in place of RHP Tanner Bibee (shoulder)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Orioles at Guardians odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:15 a.m. ET.

  • Moneyline (ML): Orioles -118 (bet $118 to win $100) | Guardians +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+134) | Guardians +1.5 (-162)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Orioles at Guardians picks and predictions

Prediction

Orioles 7, Guardians 4

Moneyline

The ORIOLES (-118) are a solid play behind the veteran Eflin, who looks to have a new lease on life after coming over from AL East rival Tampa Bay.

The Guardians (+100) have played well in this series, piling up the offense against Baltimore pitching, but they cannot be trusted behind the rookie Cantillo. The pitching scales are tipped in Baltimore’s favor Saturday.

Run line/Against the spread

Obviously, don’t play both the moneyline and the run line. But, if you’re a little less conservative, take ORIOLES -1.5 (+134). Baltimore has 4 wins in the past 7 games, and it won each of those outings by at least 2 runs. So, if you like the O’s to win, you should also like them to get the job done on the run line.

Over/Under

OVER 8.5 (-110) is a strong play, especially with the rookie going up against an angry Baltimore offense which has struggled in the first 2 games of the series.

The Over is on an 11-1 run in the past 12 games for the O’s while going 3-1 in the past 4 outings for the Guardians. Go high, and feel confidently in doing so.

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Baltimore Orioles at Cleveland Guardians odds, picks and predictions

Analyzing Friday’s Baltimore Orioles at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (65-45) and the Cleveland Guardians (66-42) play the 2nd contest of a 4-game series Friday. First pitch from Progressive Field is at 6:40 p.m. ET (ESPN+). Let’s analyze FanDuel Sportsbook’s lines around the Orioles vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 3-1

The Guardians rolled up an impressive 10-3 win in the series opener Thursday behind RHP Ben Lively. Cleveland produced 11 hits, with 4 players posting 2 or more knocks. Newcomer OF Lane Thomas, a deadline acquisition, went 2-for-4 with a pair of doubles, a walk and 2 runs scored.

The Orioles saw LHP Trevor Rogers get pounded in the opener, allowing 5 ER, 6 H and 3 BB across 4 1/3 IP in his team debut on Friday.

The 10 runs allowed by the O’s was the most since a 19-8 loss on the road against the Oakland Athletics. The Over (9) cashed Thursday, and the total has now went high at a 10-1 pace in the past 11 games for Baltimore, while going 13-2 in the past 15 outings since July 14, the final game prior to the All-Star break.

Orioles at Guardians projected starters

RHP Dean Kremer vs. RHP Carlos Carrasco

Kremer (4-7, 4.20 ERA) makes his 15th start. He has a 1.23 WHIP, 3.5 BB/9 and 8.8 K/9 in 75 IP.

  • Last start: Loss, 6 IP, 4 R (1 ER), 7 H, 1 BB, 7 K in 9-4 home setback vs. San Diego Padres last Saturday
  • 2024 road splits: 3-3, 3.05 ERA (38 1/3 IP, 13 ER), 0.97 WHIP, .174 opponents’ batting average (OBA), 13 BB, 37 K in 7 starts
  • Career vs. Guardians: 0-2, 6.23 ERA (13 IP, 9 ER), 1.46 WHIP, 5.5 K/9 in 3 starts

Carrasco (3-9, 5.68 ERA) makes his 20th start. He has a 1.40 WHIP, 2.6 BB/9 and 7.5 K/9 in 95 IP.

  • Last start: Loss, 3 2/3 IP, 6 ER, 6 H (2 HR), 1 BB, 5 K in 8-0 setback at Philadelphia Phillies last Saturday
  • 2024 home splits: 2-4, 5.36 ERA (42 IP, 25 ER), 1.45 WHIP, .307 OBA, 11 BB, 38 K in 8 starts
  • 2024 vs. Orioles: No-decision, 5 IP, 2 ER, 6 H (1 HR), 2 BB, 3 K in 4-2 road loss June 26
  • Career vs. Orioles: 4-2, 2.23 ERA (44 1/3 IP, 11 ER), 1.06 WHIP, 8.1 K/9 in 7 starts (8 appearances)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Orioles at Guardians odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:48 a.m. ET.

  • Moneyline (ML): Orioles -122 (bet $122 to win $100) | Guardians +104 (bet $100 to win $104)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+128) | Guardians +1.5 (-154)
  • Over/Under (O/U): 9 (O: -115 | U: -105)

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Orioles at Guardians picks and predictions

Prediction

Orioles 6, Guardians 5

Moneyline

The ORIOLES (-122) are worth a look as they look to avenge Thursday’s beatdown with the southpaw Rogers.

The Guardians (+104) have struggled in games which Carrasco has started, going 0-3 in his past 3 outings. Cleveland has been outscored 18-2 in those 3 starts. Cookie took a no-decision in a 4-2 loss in Baltimore on June 26, too.

Back the O’s, as they get the rebound win.

Run line/Against the spread

If you’re a little more on the conservative side, consider the GUARDIANS +1.5 (-154) catching the run and a half at home.

The Guardians are 3-1 in 4 meetings against the Orioles this season, but that only setback was a game Carrasco started, so be careful.

Over/Under

OVER 9 (-115) might be the best play on the board.

The Under might be 5-3 in the past 8 games for the Guardians at home. However, the total has gone high in 13 of the past 15 games for the Orioles.

With these 2 sub-.500 pitchers on the bump, the offenses should be able to pile up the runs.

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Baltimore Orioles at Cleveland Guardians odds, picks and predictions

Analyzing Thursday’s Baltimore Orioles at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (65-44) and the Cleveland Guardians (65-42) open a 4-game series Thursday. First pitch from Progressive Field is at 6:40 p.m. ET (ESPN+). Let’s analyze FanDuel Sportsbook’s lines around the Orioles vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 2-1

The Guardians swept a quick 2-game series at the Detroit Tigers Monday and Tuesday. They have won 3 in a row, while going 6-2 across the past 8 games. The Under is 6-1 in the past 7 for Cleveland, while cashing at a 12-3 clip in the previous 15 contests.

The Orioles took 3 of 4 games at home from the Toronto Blue Jays earlier this week, including a doubleheader split Monday. Opposite of the Guards, the O’s have hit the Over in 9 of the past 10 games, and 12-2 across the past 14 outings.

These teams met June 24-26 in Baltimore, with Cleveland taking 2 of 3 and the Under hitting in 2 of the contests.

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Orioles at Guardians projected starters

TBD vs. RHP Ben Lively

The Orioles haven’t named a starting pitcher at the time of this publishing.

Lively (9-6, 3.44 ERA) makes his 19th start. He has a 1.17 WHIP, 2.6 BB/9 and 7.8 K/9 through 99 1/3 innings.

  • Last start: Win, 6 IP, 1 ER, 3 H (1 solo HR), 2 BB, 6 K in 3-1 victory at Philadelphia Phillies last Friday
  • 2024 home splits: 5-1, 2.66 ERA (40 2/3 IP, 12 ER), 1.08 WHIP, .233 opponents’ batting average, 9 BB, 35 K in 7 starts
  • Has never faced Orioles

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Orioles at Guardians odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:28 a.m. ET.

  • Moneyline (ML): Orioles -108 (bet $108 to win $100) | Guardians -108 (bet $108 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+136) | Guardians +1.5 (-164)
  • Over/Under (O/U): 9.5 (O: -102 | U: -120)

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Orioles at Guardians picks and predictions

Prediction

Guardians 4, Orioles 3

Moneyline

The GUARDIANS (-108) are a strong play in this clash of potential playoff teams.

Lively has been one of the more consistent starting pitchers for Cleveland, and he’ll get the job done against Baltimore in this series opener.

The Guardians are an MLB-best 33-15 at home, easily the best mark in the American League. This should be a close contest, though, as the Orioles are 31-19 on the road, the 2nd-best mark in the AL — behind the Yankees (38-22).

Run line/Against the spread

If you’re a much more conservative bettor, and you don’t want to play the Guardians on the moneyline, Cleveland +1.5 (-164) isn’t priced out of line if you prefer a bit of insurance.

As a favorite, Cleveland is 4-1 on the run line in the past 5 tries.

Over/Under

UNDER 9.5 (-120) is an outstanding bet in this series opener.

The Under has cashed in 3 straight starts for Lively, while cashing at a 12-3 mark in the past 15 outings. At home, Cleveland has hit the Under at a 5-2 clip in the previous 7 outings.

For the O’s, while the Over is 12-2 across the past 14 games, the Under is 2-1 in 3 meetings with Cleveland this season.

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Baltimore Orioles at Cleveland Guardians odds, picks and predictions

Analyzing Sunday’s Baltimore Orioles at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (96-69) and the Cleveland Guardians (74-82) wrap up a 4-game series Sunday at Progressive Field. First pitch is scheduled for 1:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 4-2

The Orioles picked up a low-scoring 2-1 road victory in Saturday’s game, and Baltimore looks to grab the split in the 4-game series after losing the 1st 2 contests Thursday and Friday. The Under has cashed in 3 of the past 4 games overall for the Orioles. Despite the recent losses, Baltimore is still 1 1/2 games clear of the Tampa Bay Rays for 1st place in the AL East.

The Guardians have been eliminated from the postseason chase, but Cleveland isn’t showing any quit. It is above .500 in the past 9 games overall, including wins in 2 of the past 3 games in this series. The Under is 3-1 in the past 4 games for the Guardians, too.

Orioles at Guardians projected starters

RHP Kyle Gibson vs. RHP Triston McKenzie

Gibson (14-9, 5.00 ERA) makes his 32nd start. He has a 1.33 WHIP, 2.7 BB/9 and 7.5 K/9 in 180 innings.

  • Last start: No-decision, 4 2/3 IP, 3 ER, 5 H, 2 BB, 5 K in 9-5 in a road win vs. the Houston Astros Tuesday
  • 2023 road splits: 8-4, 4.78 ERA (105 1/3 IP, 56 ER), 13 HR, .266 OBA in 18 starts

McKenzie (0-1, 4.50 ERA) makes his 3rd start. He has a 1.20 WHIP, 3.6 BB/9 and 13.5 K/9 in 10 innings.

  • Last start: Loss, 5 IP, 5 ER, 7 H, 3 BB, 5 K in 6-4 home loss vs. the Houston Astros June 10
  • Has been on the 60-day injured list since June due to a sprained right elbow
  • Allowed 3 ER, 3 H and 1 BB with 2 K across 3 2/3 IP in a minor-league rehab start for Triple-A Columbus Tuesday

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Orioles at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:21 p.m. ET.

  • Moneyline (ML): Orioles -110 (bet $110 to win $100) | Guardians -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+155) | Guardians +1.5 (-190)
  • Over/Under (O/U):  8 (O: -115 | U: -105)

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Orioles at Guardians picks and predictions

Prediction

Orioles 4, Guardians 2

Moneyline

The ORIOLES (-110) are the play in this series finale. While the Guardians (-110) have really given the AL East leaders a hard time in Cleveland, the pitching matchup is squarely in the favor of the O’s in the final game of the set.

McKenzie is likely to be on a pitch count, and Cleveland will be very careful easing him back into the mix. Gibson, on the other hand, is a 14-game winner, and allowed 3 ER, 7 H and 1 BB across 5 2/3 IP in a win against the Guardians at Camden Yards back on May 30. Look for Gibby to handle his business again Sunday.

Run line/Against the spread

The ORIOLES -1.5 (+155) are worth a roll of the dice on the run line, although go lightly.

Baltimore failed to cover the run line Saturday, and it is 0-7 in the past 7 games on the run line as a favorite, losing 5 of the game outright.

Over/Under

The UNDER 8 (-105) is worth playing, although be cautious with McKenzie being a wild card of sorts. We don’t know what his pitch count will be, and how effective he can be against a contending Orioles team with a high-octane offense. The O’s have managed just 13 total runs of offense in the past 4 games, cashing the Under in 3 of the past 4, but you get a feeling they’re about to bust out soon.

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Baltimore Orioles at Cleveland Guardians odds, picks and predictions

Analyzing Thursday’s Baltimore Orioles at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (95-57) and Cleveland Guardians (72-81) start a 4-game series Thursday with 1st pitch from Progressive Field at 7:15 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 2-1

The Orioles had their 4-game win streak snapped on Wednesday in 2-1 loss to the Houston Astros. They look to make it 6 straight road series victories when they travel to Cleveland this weekend. Baltimore currently sits 2 1/2 games ahead of the Tampa Bay Rays in the AL East.

Cleveland returns home after being swept by the Royals in Kansas City. They allowed at least 6 runs in each of those games. The Guardians begin a 7-game homestand where they are 39-36 on the season.

Orioles at Guardians projected starters

RHP Grayson Rodriguez vs. TBD

Rodriguez (6-4, 4.53 ERA) makes his 22nd start. The rookie has a 1.34 WHIP, 3.2 BB/9 and 9.5 K/9 in 111 1/3 innings.

  • Last start: Win, 8 IP, 0 ER, 5 H, 0 BB, 7 K in 8-0 home victory against the Tampa Bay Rays
  • 2023 road stats: 3-2, 4.13 ERA (52 1/3 IP, 24 ER), .240 OBA over 10 starts
  • Never faced the Guardians as a starter

When the article was published, the Guardians had not named a starter

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Orioles at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:55 a.m. ET.

  • Moneyline (ML): Orioles -185 (bet $185 to win $100) | Guardians +150 (bet $100 to win $150)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (-110) | Guardians +1.5 (-110)
  • Over/Under (O/U): 8.5 (O: -105 | U: +115)

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Orioles at Guardians picks and predictions

Prediction

Orioles 7, Guardians 3

Moneyline

PASS.

The Orioles will likely win this game, but I’m not putting up nearly 2 units to win back 1. It’s never a good bet.

Run line/Against the spread

BET ORIOLES -1.5 (-110).

The -110 is not crazy appealing, but I don’t mind taking it in this one.

I believe Rodriguez has figured it out at the big league level. He has the tools to be a dominant starter, but struggled to get a handle on things in the majors. He manhandled the Rays in his last start over 8 innings and they are a much better team than the Guardians.

Over/Under

PASS.

We do not know the starter for the Guardians in this one and that is why I’m going to just avoid this bet completely. I really want to know the starters if I’m even going to look at the total.

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Baltimore Orioles at Cleveland Guardians odds, picks and predictions

Analyzing Thursday’s Baltimore Orioles at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Baltimore Orioles (68-61) meet the Cleveland Guardians (68-50) Thursday in the finale of a 3-game set at Progressive Field. First pitch is set for 6:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Orioles vs. Guardians odds with MLB picks and predictions.

Season series: Guardians lead 3-2.

The Orioles shut out the Guardians 4-0 Wednesday to even this series at 1. RHP Jordan Lyles pitched around 4 hits and 3 walks over 6 2/3 shutout innings. DH Ramon Urias had 3 RBIs, including a 2-run HR late to put it out of reach. Baltimore is 6-4 in its last 10 and 18-12 in the last 30.

Cleveland could only muster 5 hits Wednesday, and 4 of them came from SS Amed Rosario and 3B Jose Ramirez in the 2-3 holes in the lineup. RHP Triston McKenzie deserved a better fate, allowing just 2 ER in 5 IP with 7 K’s. The Guardians cling to a 1.5-game lead over the Minnesota Twins in the division. They need this game with their ace on the hill.

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Orioles at Guardians projected starters

RHP Kyle Bradish vs. RHP Shane Bieber

Bradish (2-5, 5.63 ERA) makes his 16th start. He has a 1.54 WHIP, 3.3 BB/9 and 8.9 K/9 in 80 IP.

  • Rookie was brilliant in last start against the Houston Astros Friday: 8 IP, 2 H, 2 BB, 6 K
  • Road warrior: 2-1, 4.79 ERA, 1.29 WHIP, 9.8 K/9 vs. 0-4, 6.29 ERA, 1.74 WHIP and 8.1 K/9

Bieber (8-7, 3.02 ERA) makes his 25th start. He has a 1.09 WHIP, 1.9 BB/9 and 9.1 K/9 in 152 IP.

  • June 3 at Baltimore: 7 IP, 2 ER, 3 H, 2 BB, 11 K
  • Last 6 starts: 1.56 ERA, 0.92 WHIP and 9.6 K/9

Orioles at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:36 a.m. ET.

  • Money line (ML): Orioles +155 (bet $100 to win $155) | Guardians -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-140) | Guardians -1.5 (+115)
  • Over/Under (O/U): 7.5 (O: -102 | U: -122)

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Orioles at Guardians picks and predictions

Prediction

Guardians 4, Orioles 2

Money line

Bieber has been one of the best pitchers no one is talking about over the last month. Two of his 3 starts against the Orioles came in 2019, but Bieber is a ridiculous 3-0 with a 0.75 ERA, 0.54 WHIP and 37 K’s in 27 IP in his career against them. The Guardians ride him to a series win Thursday. I’m not so hot on the -190 ML, but there is a SPECIAL SHANE BIEBER TO RECORD 7 K’S AND A WIN BOOSTED to +260. Strikeouts in his 3 starts against Baltimore: 11, 11 and 15. He has 8+ K’s in 4 of 6 GS so it’s worth a shot.

Run line/Against the spread

Eight of Cleveland’s last 9 victories have been by 2 or more runs. Go lightly, because these teams are pretty evenly matched, but LEAN GUARDIANS -1.5 (+115).

Over/Under

The wind is blowing in at 5 mph, which supports the gut feeling I had to go with the Under in the first place. Cleveland’s last 10 games have had 7 runs or fewer. Seven of 10 of Baltimore’s have been Under 8 as well. Money is flying in on the Under because the price went up twice during publication. Go with the UNDER 7.5 (-122).

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Baltimore Orioles at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Baltimore Orioles at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Baltimore Orioles (67-61) and the Cleveland Guardians (68-59) play the middle contest of a 3-game set at Progressive Field Wednesday. First pitch is scheduled for 6:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Orioles at Guardians odds with MLB picks and predictions.

Season series: Guardians lead 3-1

The Orioles have dropped 2 games in a row, and the offense has hit the collective skids lately. Baltimore has amassed just 2 total runs in the past 2 losses, and 14 combined runs — or 2.3 runs per game — across its last 6 showings.

The Guardians are clinging to first place in the AL Central with a 1.5 game buffer ahead of the Minnesota Twins after Cleveland’s 5-1 win over Baltimore in the series opener Tuesday.

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Orioles at Guardians projected starters

RHP Jordan Lyles vs. RHP Triston McKenzie

Lyles (9-9, 4.45 ERA) makes his 27th start. He has a 1.46 WHIP, 2.8 BB/9 and 7.5 K/9 through 145 2/3 IP.

  • Has a dismal 5.85 ERA across 75 1/3 IP over 14 road starts vs. a 2.94 ERA in 70 1/3 IP across 12 home outings
  • Is 2-1 with a 3.95 ERA over 27 1/3 IP through 5 August starts
  • Looking for back-to-back winning months for the first time Aug.-Sept. 2019 when he was a member of the Milwaukee Brewers

McKenzie (9-10, 3.17 ERA) makes his 24th start and 25th appearance. He has a 0.96 WHIP, 2.3 BB/9 and 8.7 K/9 through 147 2/3 IP.

  • Is 5-2 with a 2.78 ERA and .185 opponent batting average across 58 1/3 IP over 9 home starts
  • Allowed 5 ER with 3 HR on 3 H and 3 BB with 4 K across 7 IP in a loss at Baltimore June 4

Orioles at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6 a.m. ET.

  • Money line (ML): Orioles +140 (bet $100 to win $140) | Guardians -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-150) | Guardians -1.5 (+122)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Orioles at Guardians picks and predictions

Prediction

Guardians 4, Orioles 2

Money line

The GUARDIANS (-175) are rather heavy favorites, but they’re a good play behind McKenzie. He has been lights out at home, while Lyles has been very giving on the road. McKenzie should also have revenge on his mind after serving up 3 HR to the O’s in his first meeting with them back in early June.

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Run line/Against the spread

The GUARDIANS -1.5 (+122) are worth a roll of the dice at plus money but don’t expect this one to be a blowout. The Orioles have had trouble scoring lately, but Cleveland has dropped 3 of its last 5 games to allow Minnesota to reel it in somewhat for the division crown.

Over/Under

The UNDER 7.5 (+105) is a decent value at plus money.

The O’s have had a power outage lately, averaging just more than 2 runs per game across the previous 6 outings. The Guardians haven’t exactly set the world afire either, scoring just 12 total runs across their previous 5 contests — just 2.4 runs per game.

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